Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR103A2 Gene

Subcategory (RNA class) for MIR103A2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR103A2 Gene

  • MicroRNA 103a-2 2 3 5
  • MicroRNA 103-2 2 3
  • Hsa-Mir-103a-2 3
  • Hsa-Mir-103-2 3
  • Mir-103a-2 3
  • MIRN103-2 3
  • MIR103-2 3

External Ids for MIR103A2 Gene

ORGUL Members for MIR103A2 Gene

Previous HGNC Symbols for MIR103A2 Gene

  • MIRN103-2
  • MIR103-2

Previous GeneCards Identifiers for MIR103A2 Gene

  • GC20P003899
  • GC20P003902
  • GC20P003906

Summaries for MIR103A2 Gene

Entrez Gene Summary for MIR103A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR103A2 Gene

MIR103A2 (MicroRNA 103a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cardiomyocyte hypertrophy and MicroRNAs in cancer.

Additional gene information for MIR103A2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR103A2 Gene

Genomics for MIR103A2 Gene

Regulatory Elements for MIR103A2 Gene

Enhancers for MIR103A2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20H003871 0.5 ENCODE 11.6 -45.7 -45655 0 ZNF664 RFX1 BMI1 EP300 MIR103A2 CDC25B CENPB AP5S1 SPEF1 RNF24 PIR51563 MAVS
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR103A2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR103A2 Gene

Chromosome:
20
Start:
3,917,494 bp from pter
End:
3,917,571 bp from pter
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR103A2 Gene

Genes around MIR103A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR103A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR103A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR103A2 Gene

Proteins for MIR103A2 Gene

Post-translational modifications for MIR103A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR103A2 Gene

Domains & Families for MIR103A2 Gene

Gene Families for MIR103A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR103A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR103A2 Gene

Function for MIR103A2 Gene

Gene Ontology (GO) - Molecular Function for MIR103A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 15131085
genes like me logo Genes that share ontologies with MIR103A2: view

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR103A2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR103A2 Gene

Localization for MIR103A2 Gene

Gene Ontology (GO) - Cellular Components for MIR103A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 18766170
genes like me logo Genes that share ontologies with MIR103A2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR103A2 Gene

Pathways & Interactions for MIR103A2 Gene

genes like me logo Genes that share pathways with MIR103A2: view

Pathways by source for MIR103A2 Gene

1 BioSystems pathway for MIR103A2 Gene
1 KEGG pathway for MIR103A2 Gene

Interacting Proteins for MIR103A2 Gene

Gene Ontology (GO) - Biological Process for MIR103A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 15131085
genes like me logo Genes that share ontologies with MIR103A2: view

No data available for SIGNOR curated interactions for MIR103A2 Gene

Drugs & Compounds for MIR103A2 Gene

No Compound Related Data Available

Transcripts for MIR103A2 Gene

mRNA/cDNA for MIR103A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR103A2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR103A2 Gene

No ASD Table

Relevant External Links for MIR103A2 Gene

GeneLoc Exon Structure for
MIR103A2
ECgene alternative splicing isoforms for
MIR103A2

Expression for MIR103A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR103A2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR103A2 Gene:

MIR103A2
genes like me logo Genes that share expression patterns with MIR103A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR103A2 Gene

Orthologs for MIR103A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR103A2 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia cfa-mir-103-2 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-103-2 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-103-2 34
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir103-2 34
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-103-2 34
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-103-2 34
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-103-2 34
  • 87 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CT573279.1 34
  • 72 (a)
ManyToMany
Species where no ortholog for MIR103A2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR103A2 Gene

ENSEMBL:
Gene Tree for MIR103A2 (if available)
TreeFam:
Gene Tree for MIR103A2 (if available)

Paralogs for MIR103A2 Gene

No data available for Paralogs for MIR103A2 Gene

Variants for MIR103A2 Gene

Sequence variations from dbSNP and Humsavar for MIR103A2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs137852968 Pathogenic 3,916,955(+) AGAAG(A/C/T)GAGAG nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs148987163 Pathogenic 3,916,926(+) TCACA(G/T)CTTTG upstream-variant-2KB, splice-acceptor-variant
rs766251466 Pathogenic 3,916,956(+) GAAGC(-/GAG)AGGCT nc-transcript-variant, upstream-variant-2KB, cds-indel
rs886056651 Likely benign 3,916,913(+) TTTTT(-/CCCCCT)TCCCC intron-variant, upstream-variant-2KB
rs10679953 Benign 3,916,912(+) TCCCC(-/TCCCC/TCCCCC/TTCCCC/TTCCCCC)CATCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR103A2 Gene

Variant ID Type Subtype PubMed ID
esv3645053 CNV loss 21293372
esv3645054 CNV gain 21293372
nsv828673 CNV gain 20364138

Relevant External Links for MIR103A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR103A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR103A2 Gene

Disorders for MIR103A2 Gene

Relevant External Links for MIR103A2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR103A2

No disorders were found for MIR103A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR103A2 Gene

Publications for MIR103A2 Gene

  1. Novel MicroRNA Regulators of Atrial Natriuretic Peptide Production. (PMID: 27185878) Wu C … Newton-Cheh C (Molecular and cellular biology 2016) 3 60
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  3. miRNA-103: molecular link between insulin resistance and nonalcoholic fatty liver disease. (PMID: 25593466) Xu Q … Yao MX (World journal of gastroenterology 2015) 3 60
  4. Investigation of Gene Regulatory Networks Associated with Autism Spectrum Disorder Based on MiRNA Expression in China. (PMID: 26061495) Huang F … Jiang H (PloS one 2015) 3 60
  5. Overexpression of blood microRNAs 103a, 30b, and 29a in L-dopa-treated patients with PD. (PMID: 25596505) Serafin A … Schwienbacher C (Neurology 2015) 3 60

Products for MIR103A2 Gene

Sources for MIR103A2 Gene

Content
Loading form....