Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR103A1 Gene

Subcategory (RNA class) for MIR103A1 Gene

miRNA

Quality Score for this RNA gene is

14.2

Aliases for MIR103A1 Gene

  • MicroRNA 103a-1 2 3 5
  • MicroRNA 103-1 2 3
  • Hsa-Mir-103a-1 3
  • Hsa-Mir-103-1 3
  • Mir-103a-1 3
  • MIRN103-1 3
  • MIR103-1 3

External Ids for MIR103A1 Gene

Previous HGNC Symbols for MIR103A1 Gene

  • MIRN103-1
  • MIR103-1

Previous GeneCards Identifiers for MIR103A1 Gene

  • GC05M167988

Summaries for MIR103A1 Gene

Entrez Gene Summary for MIR103A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR103A1 Gene

MIR103A1 (MicroRNA 103a-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and MicroRNAs in cardiomyocyte hypertrophy.

fRNAdb sequence ontologies for MIR103A1 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR103A1

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR103A1 Gene

Genomics for MIR103A1 Gene

Genomic Location for MIR103A1 Gene

Chromosome:
5
Start:
168,560,892 bp from pter
End:
168,560,977 bp from pter
Size:
86 bases
Orientation:
Minus strand

Genomic View for MIR103A1 Gene

Genes around MIR103A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR103A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR103A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR103A1 Gene

ORGUL Member Location for MIR103A1 Gene

ORGUL Member Location for MIR103A1 gene

No data available for Regulatory Elements for MIR103A1 Gene

Proteins for MIR103A1 Gene

Post-translational modifications for MIR103A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR103A1 Gene

Domains & Families for MIR103A1 Gene

Gene Families for MIR103A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR103A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR103A1 Gene

Function for MIR103A1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR103A1 Gene

Localization for MIR103A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR103A1 Gene

Pathways & Interactions for MIR103A1 Gene

genes like me logo Genes that share pathways with MIR103A1: view

Pathways by source for MIR103A1 Gene

1 BioSystems pathway for MIR103A1 Gene
1 KEGG pathway for MIR103A1 Gene

Interacting Proteins for MIR103A1 Gene

Gene Ontology (GO) - Biological Process for MIR103A1 Gene

None

No data available for SIGNOR curated interactions for MIR103A1 Gene

Drugs & Compounds for MIR103A1 Gene

No Compound Related Data Available

Transcripts for MIR103A1 Gene

fRNAdb Secondary structures for MIR103A1 Gene

  • hsa-mir-103a-1_MI0000109_Homo_sapiens_miR-103a-1_stem-loop_hairpin
  • AF480545

mRNA/cDNA for MIR103A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR103A1 Gene

No ASD Table

Relevant External Links for MIR103A1 Gene

GeneLoc Exon Structure for
MIR103A1
ECgene alternative splicing isoforms for
MIR103A1

Expression for MIR103A1 Gene

mRNA expression in normal human tissues for MIR103A1 Gene

genes like me logo Genes that share expression patterns with MIR103A1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR103A1 Gene

Orthologs for MIR103A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR103A1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-103-1 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-103-1 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir103-1 36
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-103-1 36
  • 65 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-103-1 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-103-1 36
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-103 36
  • 68 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-103 36
  • 72 (a)
ManyToMany
Species with no ortholog for MIR103A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR103A1 Gene

ENSEMBL:
Gene Tree for MIR103A1 (if available)
TreeFam:
Gene Tree for MIR103A1 (if available)

Paralogs for MIR103A1 Gene

No data available for Paralogs for MIR103A1 Gene

Variants for MIR103A1 Gene

Relevant External Links for MIR103A1 Gene

HapMap Linkage Disequilibrium report
MIR103A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR103A1 Gene

Disorders for MIR103A1 Gene

Relevant External Links for MIR103A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR103A1

No disorders were found for MIR103A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR103A1 Gene

Publications for MIR103A1 Gene

  1. miR-103/107 modulates multidrug resistance in human gastric carcinoma by downregulating Cav-1. (PMID: 25407491) Zhang Y. … Liu Y. (Tumour Biol. 2015) 3
  2. miRNA-103: molecular link between insulin resistance and nonalcoholic fatty liver disease. (PMID: 25593466) Xu Q. … Yao M.X. (World J. Gastroenterol. 2015) 3
  3. Overexpression of blood microRNAs 103a, 30b, and 29a in L-dopa-treated patients with PD. (PMID: 25596505) Serafin A. … Schwienbacher C. (Neurology 2015) 3
  4. MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN. (PMID: 24828205) Geng L. … Fang X.D. (Int J Mol Sci 2014) 3
  5. MiR-103a-3p targets the 5' UTR of GPRC5A in pancreatic cells. (PMID: 24984703) Zhou H. … Rigoutsos I. (RNA 2014) 3

Products for MIR103A1 Gene

Sources for MIR103A1 Gene

Back to Top

Content