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Aliases for MIR101-2 Gene

Subcategory (RNA class) for MIR101-2 Gene


Quality Score for this RNA gene is


Aliases for MIR101-2 Gene

  • MicroRNA 101-2 2 3
  • Hsa-Mir-101-2 3
  • Mir-101-2 3
  • MIRN101-2 3

External Ids for MIR101-2 Gene

Previous HGNC Symbols for MIR101-2 Gene

  • MIRN101-2

Previous GeneCards Identifiers for MIR101-2 Gene

  • GC09P004843
  • GC09P004852
  • GC09P004855
  • GC09P004854

Summaries for MIR101-2 Gene

Entrez Gene Summary for MIR101-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR101-2 Gene

MIR101-2 (MicroRNA 101-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR101-2 Gene

Genomics for MIR101-2 Gene

Genomic Location for MIR101-2 Gene

4,850,291 bp from pter
4,850,381 bp from pter
91 bases
Plus strand

Genomic View for MIR101-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR101-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR101-2 Gene

No data available for Regulatory Elements for MIR101-2 Gene

Proteins for MIR101-2 Gene

Post-translational modifications for MIR101-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR101-2 Gene

Domains & Families for MIR101-2 Gene

Gene Families for MIR101-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR101-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR101-2 Gene

Function for MIR101-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR101-2 Gene

Localization for MIR101-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR101-2 Gene

Pathways & Interactions for MIR101-2 Gene

SuperPathways for MIR101-2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR101-2: view

Pathways by source for MIR101-2 Gene

1 KEGG pathway for MIR101-2 Gene

Interacting Proteins for MIR101-2 Gene

Gene Ontology (GO) - Biological Process for MIR101-2 Gene


No data available for SIGNOR curated interactions for MIR101-2 Gene

Drugs & Compounds for MIR101-2 Gene

No Compound Related Data Available

Transcripts for MIR101-2 Gene

mRNA/cDNA for MIR101-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR101-2 Gene

No ASD Table

Relevant External Links for MIR101-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR101-2 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR101-2 Gene

Orthologs for MIR101-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR101-2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-101-2 36
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-101-2 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-101-2 36
  • 99 (a)
(Mus musculus)
Mammalia Mir101b 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-101-2 36
  • 97 (a)
oan-mir-101-2 36
  • 97 (a)
(Pan troglodytes)
Mammalia ptr-mir-101-2 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-101-1 36
  • 95 (a)
(Anolis carolinensis)
Reptilia aca-mir-101-2 36
  • 98 (a)
(Danio rerio)
Actinopterygii dre-mir-101b 36
  • 64 (a)
Species with no ortholog for MIR101-2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR101-2 Gene

Gene Tree for MIR101-2 (if available)
Gene Tree for MIR101-2 (if available)

Paralogs for MIR101-2 Gene

No data available for Paralogs for MIR101-2 Gene

Variants for MIR101-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR101-2 Gene

Variant ID Type Subtype PubMed ID
nsv892131 CNV Loss 21882294
nsv892132 CNV Gain 21882294
nsv892133 CNV Gain 21882294

Relevant External Links for MIR101-2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR101-2 Gene

Disorders for MIR101-2 Gene

Relevant External Links for MIR101-2

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR101-2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR101-2 Gene

Publications for MIR101-2 Gene

  1. miR-101 acts as a tumor suppressor by targeting Kruppel-like factor 6 in glioblastoma stem cells. (PMID: 25230316) Yao Y.L. … Liu Y.H. (CNS Neurosci Ther 2015) 67
  2. Genetic variations in the flanking regions of miR-101-2 are associated with increased risk of breast cancer. (PMID: 24475105) Chen J. … Shen H. (PLoS ONE 2014) 67
  3. miR-101 regulates expression of EZH2 and contributes to progression of and cisplatin resistance in epithelial ovarian cancer. (PMID: 25260883) Liu L. … Wang Z. (Tumour Biol. 2014) 67
  4. MiR-101, downregulated in retinoblastoma, functions as a tumor suppressor in human retinoblastoma cells by targeting EZH2. (PMID: 24807198) Lei Q. … Zhang L. (Oncol. Rep. 2014) 67
  5. A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells. (PMID: 25260594) Liu J.J. … Yang J. (Nucleic Acids Res. 2014) 67

Products for MIR101-2 Gene

Sources for MIR101-2 Gene

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