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Aliases for MIR101-1 Gene

Subcategory (RNA class) for MIR101-1 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR101-1 Gene

  • MicroRNA 101-1 2 3
  • MIRN101-1 3 6
  • Hsa-Mir-101-1 3

External Ids for MIR101-1 Gene

Previous HGNC Symbols for MIR101-1 Gene

  • MIRN101-1

Previous GeneCards Identifiers for MIR101-1 Gene

  • GC01M065297
  • GC01M065524

Summaries for MIR101-1 Gene

Entrez Gene Summary for MIR101-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR101-1 Gene

MIR101-1 (MicroRNA 101-1) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR101-1 include adult t-cell leukemia. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR101-1 Gene

Genomics for MIR101-1 Gene

Genomic Location for MIR101-1 Gene

Start:
65,058,434 bp from pter
End:
65,058,508 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for MIR101-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR101-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR101-1 Gene

ORGUL Member Location for MIR101-1 Gene

ORGUL Member Location for MIR101-1 gene

No data available for Regulatory Elements for MIR101-1 Gene

Proteins for MIR101-1 Gene

Post-translational modifications for MIR101-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR101-1 Gene

Domains for MIR101-1 Gene

Gene Families for MIR101-1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR101-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR101-1 Gene

Function for MIR101-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR101-1 Gene

Localization for MIR101-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR101-1 Gene

Pathways for MIR101-1 Gene

SuperPathways for MIR101-1 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR101-1: view

Pathways by source for MIR101-1 Gene

1 KEGG pathway for MIR101-1 Gene

Interacting Proteins for MIR101-1 Gene

Gene Ontology (GO) - Biological Process for MIR101-1 Gene

None

Transcripts for MIR101-1 Gene

mRNA/cDNA for MIR101-1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR101-1 Gene

No ASD Table

Relevant External Links for MIR101-1 Gene

GeneLoc Exon Structure for
MIR101-1
ECgene alternative splicing isoforms for
MIR101-1

Expression for MIR101-1 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR101-1 Gene

Orthologs for MIR101-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR101-1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-101-1 36
  • 89 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-101-1 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-101-1 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir101a 36
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-101-1 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-101-1 36
  • 89 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-101-2 36
  • 95 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-101-1 36
  • 88 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-101a 36
  • 86 (a)
OneToOne
Species with no ortholog for MIR101-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR101-1 Gene

ENSEMBL:
Gene Tree for MIR101-1 (if available)
TreeFam:
Gene Tree for MIR101-1 (if available)

Paralogs for MIR101-1 Gene

No data available for Paralogs for MIR101-1 Gene

Variants for MIR101-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR101-1 Gene

Variant ID Type Subtype PubMed ID
nsv830059 CNV Loss 17160897
esv2676423 CNV Deletion 23128226

Relevant External Links for MIR101-1 Gene

HapMap Linkage Disequilibrium report
MIR101-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR101-1 Gene

Disorders for MIR101-1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR101-1 Gene including...

Search for MIR101-1 Gene in MalaCards »

Relevant External Links for MIR101-1

Human Genome Epidemiology (HuGE) Navigator
MIR101-1
genes like me logo Genes that share disorders with MIR101-1: view

No data available for UniProtKB/Swiss-Prot for MIR101-1 Gene

Publications for MIR101-1 Gene

  1. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. (PMID: 11914277) Mourelatos Z. … Dreyfuss G. (Genes Dev. 2002) 3
  2. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR101-1 Gene

Sources for MIR101-1 Gene

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