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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MIR100HG Gene

RNA gene GIFtS: 22
GCID: GC11M121961

mir-100-let-7a-2 cluster host gene (non-protein coding)

Explore 2 diseases affiliated with
MIR100HG via

MalaCards

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 2

Aliases
Mir-100-Let-7a-2 Cluster Host Gene (Non-Protein Coding)¹ ²

External Ids:	HGNC: 39522¹	Entrez Gene: 399959²

ORGUL members:
	NONCODE:n386026 n381788 n341142 n381786

Export aliases for MIR100HG gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_033899.8

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for MIR100HG
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

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Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR100HG

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.1 HGNC cytogenetic band: 11q24.1

MIR100HG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MIR100HG gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M121961: view genomic region (about GC identifiers)

Start:	121,959,811 bp from pter	End:	122,073,770 bp from pter
Size:	113,960 bases	Orientation:	minus strand

MIR100HG has overlapping exons with:

ENSG00000255248

ORGUL member locations:
Legend (see complete legend)

n381786
n386026
n341142
n381788

lncRNA
Full Legend

121959810 122016790 122073770 chr11

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
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UniProtKB: --

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

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Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MIR100HG

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
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Browse Small Molecules at EMD Millipore

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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Clusters for MIR100HG:

Mir-100-let-7a-2 cluster host gene (non-protein coding)

Hs.44098 [show with all ESTs], Hs.732590 [show with all ESTs]

Unigene Representative Sequences: AK123947, AB075498

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Additional cDNA sequence:

AB075498.1 AK091713.1 AK311309.1 AL832469.1 BC040599.1 BX538058.1 NR_024430.1

23 DOTS entries:

DT.95089767 DT.211601 DT.92053401 DT.95264897 DT.120737828 DT.97842184 DT.100752275 DT.120737783

DT.120737767 DT.95264898 DT.97842182 DT.120737786 DT.120737871 DT.40243724 DT.40315345 DT.101964246

DT.120737703 DT.120737776 DT.120737860 DT.120737867 DT.75143417 DT.91979339 DT.97800803

24/139 AceView cDNA sequences (see all 139):

CA418008 AW169201 AA428694 AU117663 BQ021459 BM541657 BI753385 BM672072

AA401861 AI027125 CA396628 CA396990 BM460512 BX538058 BF060946 AI783770

BX381192 BM893692 BM966955 BQ959997 BM462594 AA887671 AA613964 AU118519

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for MIR100HG:none

MIR100HG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATAATTGTTG

About this image

MIR100HG expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

CD31, CD144 positive cells (Two-step protocol fo...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Genevestigator expression for MIR100HG

SOURCE GeneReport for Unigene clusters: Hs.44098 Hs.732590

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs12801593^1,2		--	117906265(+)	`TTCCTC/G/TGTGGA`	2	--	ds500¹ int¹		0	--	--	--	--
rs12801936^1,2	H,	--	117906266(+)	`TCCTCA/G/TTGGAT`	2	--	ds500¹ int¹		5		NS EA WA	538
rs12801452^1,2	H	--	117906282(+)	`AACTAA/TCTTTG`	2	--	int¹ ds500¹		4		NS EA	420
rs12801866^1,2	H	--	117906435(+)	`TTGTGC/TTTGGC`	2	--	int¹ nc-transcript-variant		4		NS EA	416
rs3087678^1,2	C,F,A,H,	--	117906795(-)	`AGCCAC/TAGAAA`	2	--	nc-transcript-variantint¹		14		MN NS EA NA WA CSA	971
rs7940586^1,2	H	--	117906865(+)	`ATTTTT/AAAAAA`	2	--	nc-transcript-variantint¹		4		NS EA	416
rs112066170^1,2		--	117907072(+)	`AACCAT/CTGACA`	2	--	int¹ nc-transcript-variant		2		CSA EA	122
rs78343022^1,2		--	117907485(+)	`AAAAAA/CAAGTC`	2	--	nc-transcript-variantint¹		1		CSA	1
rs661788^1,2	H,	--	117907525(+)	`TTTTTT/CCCCAA`	2	--	nc-transcript-variantint¹		4		NS EA	420
rs12276240^1,2	F,H,	--	117907650(+)	`GGAATA/TTAAAA`	2	--	int¹ nc-transcript-variant		4		NS EA	414

HapMap Linkage Disequilibrium report for MIR100HG (121959811 - 122073770 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MIR100HG: --

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIR100HG

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MIR100HG for disorders About GeneDecksing

2 diseases for MIR100HG: About MalaCards

myopia 11 myopia

Export disorders for MIR100HG gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MIR100HG gene integrated from 9 sources:
(articles sorted by number of sources associating them with MIR100HG)

Utopia: connect your pdf to the dynamic
world of online information

Evaluation of BLID and LOC399959 as candidate genes f or high myopia in the Chinese Han population. (PubMed id 21031016)¹ Zhao F....Zhou X. (2010)
A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. (PubMed id 19779542)¹ Nakanishi H....Matsuda F. (2009)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 399959	HGNC: 39522	AceView: LOC399959	euGenes: HUgn399959	ECgene: MIR100HG
H-InvDB: MIR100HG

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Intellectual Property for MIR100HG gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MIR100HG gene:
Search GeneIP for patents involving MIR100HG

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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MIR100HG Gene

mir-100-let-7a-2 cluster host gene (non-protein coding)

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mir-100-let-7a-2 cluster host gene (non-protein coding)

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