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Aliases for MIR1-1 Gene

Subcategory (RNA class) for MIR1-1 Gene


Quality Score for this RNA gene is


Aliases for MIR1-1 Gene

  • MicroRNA 1-1 2 3 5
  • Hsa-Mir-1-1 3
  • MiRNA1-1 3
  • Mir-1-1 3
  • MIRN1-1 3

External Ids for MIR1-1 Gene

ORGUL Members for MIR1-1 Gene

Previous HGNC Symbols for MIR1-1 Gene

  • MIRN1-1

Previous GeneCards Identifiers for MIR1-1 Gene

  • GC20P060563
  • GC20P061153
  • GC20P061156
  • GC20P061159
  • GC20P062652
  • GC20P062656
  • GC20P062704
  • GC20P062723
  • GC20P062779

Summaries for MIR1-1 Gene

Entrez Gene Summary for MIR1-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1-1 Gene

MIR1-1 (MicroRNA 1-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRs in Muscle Cell Differentiation and Heart Development.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1-1 Gene

Genomics for MIR1-1 Gene

Regulatory Elements for MIR1-1 Gene

Enhancers for MIR1-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20G062738 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.5 +186.4 186378 4.9 PKNOX1 ATF1 SIN3A ZNF766 GLIS2 GATA2 ELK1 FOS JUNB MIER2 OGFR NTSR1 LINC00659 LINC00686 OGFR-AS1 MIR1-1 C20orf166-AS1 MIR1-1HG ENSG00000229882 ENSG00000232121
GH20G062425 1.5 Ensembl ENCODE dbSUPER 11 -125.3 -125296 6.4 HDGF PKNOX1 ATF1 SIN3A ZBTB7B ZNF207 FOS SP5 REST ZNF592 CABLES2 LOC105372710 ARFGAP1 LAMA5 MIR1-1 C20orf166-AS1 MIR1-1HG RBBP8NL GATA5
GH20G062589 1.3 FANTOM5 ENCODE dbSUPER 11.7 +35.9 35872 1.8 GTF2F1 TBP MXI1 TAF1 MAX SIN3A PAX8 RAD21 POLR2A SMC3 MIR1-1HG C20orf166-AS1 MIR133A2 ENSG00000229882 ENSG00000232121 MIR1-1 ENSG00000264490 WI2-87327B8.2
GH20G062641 1.3 ENCODE dbSUPER 11 +91.1 91076 8.0 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B SLCO4A1-AS1 OGFR OGFR-AS1 MIR1-1HG MIR1-1 C20orf166-AS1 TCFL5 NKAIN4 GC20P062803 ENSG00000167046
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR1-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR1-1 Gene

62,554,306 bp from pter
62,554,376 bp from pter
71 bases
Plus strand

Genomic View for MIR1-1 Gene

Genes around MIR1-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1-1 Gene

Proteins for MIR1-1 Gene

Post-translational modifications for MIR1-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1-1 Gene

Domains & Families for MIR1-1 Gene

Gene Families for MIR1-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1-1 Gene

Function for MIR1-1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1-1 Gene

Localization for MIR1-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR1-1 Gene

Pathways & Interactions for MIR1-1 Gene

genes like me logo Genes that share pathways with MIR1-1: view

Pathways by source for MIR1-1 Gene

Interacting Proteins for MIR1-1 Gene

Gene Ontology (GO) - Biological Process for MIR1-1 Gene


No data available for SIGNOR curated interactions for MIR1-1 Gene

Drugs & Compounds for MIR1-1 Gene

No Compound Related Data Available

Transcripts for MIR1-1 Gene

mRNA/cDNA for MIR1-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1-1 Gene

No ASD Table

Relevant External Links for MIR1-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1-1 Gene

genes like me logo Genes that share expression patterns with MIR1-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1-1 Gene

Orthologs for MIR1-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR1-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia cfa-mir-1-1 35
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-1-1 35
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-1-1 35
  • 97 (a)
(Mus musculus)
Mammalia Mir1a-1 35
  • 96 (a)
(Monodelphis domestica)
Mammalia mdo-mir-1-2 35
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 68 (a)
(Gallus gallus)
Aves gga-mir-1a-1 35
  • 90 (a)
(Anolis carolinensis)
Reptilia aca-mir-1a-2 35
  • 70 (a)
(Danio rerio)
Actinopterygii mir1-1 35
  • 63 (a)
Species where no ortholog for MIR1-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR1-1 Gene

Gene Tree for MIR1-1 (if available)
Gene Tree for MIR1-1 (if available)

Paralogs for MIR1-1 Gene

No data available for Paralogs for MIR1-1 Gene

Variants for MIR1-1 Gene

Sequence variations from dbSNP and Humsavar for MIR1-1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000690030 -- 62,554,625(+) GGCGC(A/G)GGGTC intron-variant, downstream-variant-500B
rs1001697706 -- 62,554,278(+) CGGGG(C/T)CTTGG intron-variant, upstream-variant-2KB
rs1003105531 -- 62,553,370(+) CGAGG(C/T)GGGGA intron-variant, upstream-variant-2KB
rs1005200081 -- 62,554,419(+) CACCA(C/T)GGGGG intron-variant, downstream-variant-500B
rs1006474434 -- 62,554,082(+) GAGGG(A/G)CGCCG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR1-1 Gene

Variant ID Type Subtype PubMed ID
dgv4343n100 CNV gain 25217958
dgv4344n100 CNV gain 25217958
esv2422398 CNV duplication 17116639
nsv459065 CNV gain 19166990
nsv459068 CNV gain 19166990
nsv470556 CNV loss 18288195
nsv586496 CNV gain 21841781
nsv586501 CNV gain 21841781
nsv953302 CNV deletion 24416366

Relevant External Links for MIR1-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1-1 Gene

Disorders for MIR1-1 Gene

Relevant External Links for MIR1-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR1-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1-1 Gene

Publications for MIR1-1 Gene

  1. Analysis of Circulating miR-1, miR-23a, and miR-26a in Atrial Fibrillation Patients Undergoing Coronary Bypass Artery Grafting Surgery. (PMID: 28422282) Feldman A. … Farsky P. (Ann. Hum. Genet. 2017) 3 64
  2. Dual-receptor (EGFR and c-MET) inhibition by tumor-suppressive miR-1 and miR-206 in head and neck squamous cell carcinoma. (PMID: 27169691) Koshizuka K. … Seki N. (J. Hum. Genet. 2017) 3 64
  3. Analysis of the Indicating Value of Cardiac Troponin I, Tumor Necrosis Factor-I+, Interleukin-18, Mir-1 and Mir-146b for Viral Myocarditis among Children. (PMID: 27997912) Wang D. … Zhang Y. (Cell. Physiol. Biochem. 2016) 3 64
  4. miR-1 association with cell proliferation inhibition and apoptosis in vestibular schwannoma by targeting VEGFA. (PMID: 27819721) Li S.L. … Zhang Y. (Genet. Mol. Res. 2016) 3 64
  5. miR-1 Inhibits Cell Growth, Migration, and Invasion by Targeting VEGFA in Osteosarcoma Cells. (PMID: 27777493) Niu J. … Liu B. (Dis. Markers 2016) 3 64

Products for MIR1-1 Gene

Sources for MIR1-1 Gene

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