MIP Gene
protein-coding GIFtS: 56
GCID: GC12M056843
|
|
major intrinsic protein of lens fiber
| |
Aliases
for MIP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Major Intrinsic Protein Of Lens Fiber1 2 | | MIP262 3 | | AQP01 2 3 5 | | Aquaporin 02 | | MP261 2 3 | | Lens Fiber Major Intrinsic Protein2 | | LIM11 2 | | Aquaporin-03 |
Export aliases for MIP gene to outside databasesPrevious GC identifers: GC12P056780 GC12M057069 GC12M056561 GC12M055131 GC12M053882 |
Summaries
for MIP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MIP:
Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIPfamily of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yetthis protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocularlens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in apotential gene cluster at 12q13. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MIP_HUMAN, P30301Function: Water channel. May be responsible for regulating the osmolarity of the lens. Interactions betweenhomotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity)
Gene Wiki entry for MIP
|
Genomic Views
for MIP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MIP gene promoter:
Sp1 AP-2alpha isoform 3 ATF-2 AP-2alpha isoform 2 Max AP-2alpha isoform 4 AP-2alpha AP-2alphaA c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for MIP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13MIP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M056843: view genomic region
(about GC identifiers)
Start:
|
56,843,286 bp from pter |
End:
|
56,862,950 bp from pter |
Size:
|
19,665 bases |
Orientation:
|
minus strand |
|
Proteins
for MIP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MIP_HUMAN, P30301 (See
protein sequence)Recommended Name: Lens fiber major intrinsic protein Size: 263 amino acids; 28122 Da
Subunit: Homotetramer. Homooctamer formed by head-to-head interaction between homotetramers from adjoining membranes(By similarity)
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Secondary accessions: Q17R41Explore the universe of human proteins at neXtProt for MIP: NX_P30301
Post-translational modifications:
Subject to partial proteolytic cleavage in the eye lens core. Partial proteolysis promotes interactions betweentetramers from adjoining membranes (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P30301
MIP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036196.1
ENSEMBL proteins: ENSP00000257979 Reactome Protein details: P30301
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
MIP for ontologies About GeneDecksing
MIP Antibody Products:
Assay Products for MIP: |
Protein
Domains /
Families
for MIP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MIP for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P30301ProtoNet protein and cluster: P30301 1 Blocks protein family: IPB000425 MIP family
UniProtKB/Swiss-Prot: MIP_HUMAN, P30301Domain: Aquaporins contain two tandem repeats each containing two membrane-spanning helices and a pore-forming loopwith the signature motif Asn-Pro-Ala (NPA). Each tandem repeat contains a loop and a short helix that enter and leavethe lipid bilayer on the same side (By similarity)Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family |
Function
for MIP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MIP_HUMAN, P30301Function: Water channel. May be responsible for regulating the osmolarity of the lens. Interactions betweenhomotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity) Genatlas biochemistry entry for MIP:major intrinsic protein of lens fiber,1 (MP26),with water channel properties
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MIP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MIP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MIP (NM_012064) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MIP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MIP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIP |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
MIP for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MIP:
Animal Models:
1 MGI mutant phenotype (inferred from 5 alleles ) (MGI details for Mip):
MIP for phenotypes About GeneDecksing
|
Pathways & Interactions
for MIP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Passive Transport by Aquaporins | | | 2 | Regulation of Water Balance by Renal Aquaporins | | | 3 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for MIP
MIP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MIP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/13 Interacting proteins for MIP (P303013 ENSP000002579794) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
MIP for ontologies About GeneDecksing
|
Drugs & Compounds
for MIP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MIP for compounds About GeneDecksing
 Browse Tocris compounds for MIP
10/47 Novoseek chemical compound relationships for MIP gene (see all 47) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| glycerol |
76.8 |
77 |
9430617 (4), 10066730 (4), 14646142 (3), 19273130 (2) (see all 45) |
| hgcl2 |
63.2 |
8 |
18565621 (2), 11351098 (1), 19513079 (1), 14739264 (1) (see all 6) |
| pcmbs |
56.8 |
5 |
10684866 (1), 11297562 (1), 19484468 (1), 8584435 (1) |
| mp 26 |
55.6 |
2 |
1840563 (1), 1911643 (1) |
| cp-49 |
52.8 |
3 |
16565393 (2), 15593327 (1) |
| mercury chloride |
50.5 |
1 |
19772916 (1) |
| urea |
45.7 |
18 |
20149227 (2), 8810261 (2), 19096786 (2), 18444909 (1) (see all 9) |
| arsenite |
32 |
5 |
19442679 (1), 19096773 (1), 18626020 (1), 19350206 (1) (see all 5) |
| abscisic acid |
31.9 |
2 |
20047666 (1), 18266903 (1) |
| mercury |
30.4 |
14 |
16926168 (3), 8624437 (3), 12435590 (1), 17376483 (1) (see all 6) |
Search CenterWatch for drugs/clinical trials and news about MIP
|
Transcripts
for MIP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MIP gene: NM_012064.3 Unigene Cluster for MIP: Major intrinsic protein of lens fiber Hs.574026 [show with all ESTs]Unigene Representative Sequence: NM_0120643 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000257979(uc001slh.3) ENST00000557333 ENST00000555551
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MIP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MIP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MIP (NM_012064) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MIP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MIP |
Additional cDNA sequence: AK307357.1 BC074913.2 BC117474.1 2 DOTS entries: DT.97842105 DT.97822611 24/31 AceView cDNA sequences (see all 31): BM706175 BM699762 BC074913 BF727073 BF727203 BM931729 BF727058 CD675949 NM_012064 BM931718 BM680375 BU738134 BM696300 CD675761 BF727057 BM720012 BM712038 BM544430 BM700190 BU735357 BM705682 BM705396 BM670318 AV702421
GeneLoc Exon Structure
|
Expression
for MIP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MIP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See MIP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MIP
SOURCE GeneReport for Unigene cluster: Hs.574026
UniProtKB/Swiss-Prot: MIP_HUMAN, P30301Tissue specificity: Major component of lens fiber gap junctions
SABiosciences Custom PCR Arrays for MIP
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MIP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MIP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIP |
Orthologs
for MIP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MIP gene from 5/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
MIP6 |
-- |
74(a) |
1 ↔ 1 |
2(93204104-93211524) |
zebrafish
(Danio rerio) |
Actinopterygii |
mipa1 |
major intrinsic protein of lens fiber a |
67.68(n)
70.34(a) |
|
445140 NM_001003534.1 NP_001003534.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG77773 |
water transporter |
38(a) |
|
47F13 -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
TIP2;21 |
putative aquaporin TIP2-2 |
48.48(n)
38.76(a) |
|
827446 NM_117838.3 NP_193465.1 |
rice
(Oryza sativa) |
Liliopsida |
Os02g06581001 |
hypothetical protein |
52.86(n)
41.9(a) |
|
4330207 NM_001054167.1 NP_001047632.1 |
ENSEMBL Gene Tree for MIP (if available)
TreeFam Gene Tree for MIP (if available) |
Paralogs
for MIP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MIP gene
- ENSG000002504242 AQP22 AQP82 AQP52 AQP12 AQP42 AQP62
7 SIMAP similar genes for MIP using alignment to 1 protein entry: MIP_HUMAN:AQP5 AQP6 AQP2 AQP1 DKFZp434D2030 AQP4
AQP8
MIP for paralogs About GeneDecksing
|
Genomic Variants
for MIP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MIP (56843286 - 56862950 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MIP
1 CNV: 0164
Human Gene Mutation Database (HGMD): MIP
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIP |
|
Disorders
/ Diseases
for MIP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MIP for disorders About GeneDecksing
OMIM gene information: 154050
OMIM disorders: 604219
UniProtKB/Swiss-Prot: MIP_HUMAN, P30301
Defects in MIP are a cause of cataract autosomal dominant (ADC) [MIM:604219]. Cataract is an opacification ofthe crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary inmorphology, are often confined to a portion of the lens, and may be static or progressive. In general, the moreposteriorly located and dense an opacity, the greater the impact on visual function. Cataract is the most commontreatable cause of visual disability in childhood
20/50  diseases for MIP (see all 50): About MalaCardscataract, polymorphic and lamellar endolymphatic hydrops diabetes insipidus nephrogenic diabetes insipidus
cataract cerulean cataract cataracts, autosomal dominant traumatic brain injury
duchenne muscular dystrophy muscular dystrophy arachnoid cysts brain edema
meniere's disease menieres disease brain injury arachnoiditis
congenital cataracts corneal edema legionellosis insulin resistance
2 diseases from the University of Copenhagen DISEASES database for MIP:Senile cataract Diabetic cataract 10/44 Novoseek disease relationships for MIP gene (see all 44) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| water balance disorders |
92.7 |
11 |
11320486 (2), 9818197 (1), 20142913 (1), 17222168 (1) (see all 10) |
| diabetes insipidus nephrogenic |
82.8 |
4 |
19448080 (1), 8717630 (1) |
| brain edema |
67.5 |
16 |
16313100 (3), 16181079 (2), 15120208 (2), 11115728 (1) (see all 12) |
| congenital cataract |
48.7 |
2 |
20361015 (2) |
| cerebral edema |
43.5 |
4 |
14753494 (2), 20168229 (1), 17618977 (1) |
| cataract |
40.1 |
23 |
11090476 (2), 19023964 (2), 11001937 (2), 19448080 (1) (see all 14) |
| edema |
39.9 |
12 |
19566827 (2), 10652478 (1), 15561416 (1), 11243009 (1) (see all 11) |
| water intoxication |
37.5 |
1 |
15120208 (1) |
| endolymphatic hydrops |
36 |
1 |
15377953 (1) |
| aqueous humor |
33.4 |
5 |
9497312 (1), 10694901 (1), 10873606 (1), 9733591 (1) (see all 5) |
Human Genome Epidemiology (HuGE) Navigator: MIP (21 documents)
Export disorders for MIP gene to outside databases
|
Publications
for MIP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MIP gene, integrated from 9 sources (see all 407):
(articles sorted by number of sources associating them with MIP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens. (PubMed id 1840563)1, 2, 3, 9 Pisano M.M. and Chepelinsky A.B. (1991)
- Missense mutations in MIP underlie autosomal dominant 'polymorphic' and lamellar cataracts linked to 12q. (PubMed id 10802646)1, 2, 9 Berry V.... Bhattacharya S. (2000)
- Functional impairment of lens aquaporin in two families with dominantly inherited cataracts. (PubMed id 11001937)1, 2, 9 Francis P.... Agre P. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Characterization of human lens major intrinsic protein structure. (PubMed id 10634618)1, 2 Schey K.L.... Crouch R.K. (2000)
- Water channel properties of major intrinsic protein o f lens. (PubMed id 7536742)1, 3 Mulders S.M....Agre P. (1995)
- Intact AQP0 performs cell-to-cell adhesion. (PubMed id 19857466)1, 9 Kumari S.S. and Varadaraj K. (2009)
- Interactions of lipids with aquaporin-0 and other membrane proteins. (PubMed id 17932686)1, 9 Hite R.K....Walz T. (2008)
- Post-translational modifications of aquaporin 0 (AQP0) in the normal human lens: spatial and temporal occurrence. (PubMed id 15274640)1, 9 Ball L.E....Schey K.L. (2004)
- Functional characterization of a human aquaporin 0 mutation that leads to a congenital dominant lens cataract. (PubMed id 18501347)1, 9 Varadaraj K....Mathias R.T. (2008)
|
External Searches for MIP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MIP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MIP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MIP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MIP | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MIP gene:
Search GeneIP for patents involving MIP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MIP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MIP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MIP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MIP | | | OriGene Protein Over-expression Lysate for MIP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MIP | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MIP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MIP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MIP | | OriGene Custom Protein Services for MIP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MIP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MIP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIP |
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| | | | Search Tocris compounds for MIP |
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 | | | MIP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIP |
|  |  |  | | | | Search ThermoFisher Antibodies for MIP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MIP |
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