MINPP1 Gene
protein-coding GIFtS: 64
GCID: GC10P089264
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multiple inositol-polyphosphate phosphatase 1(Previous names: multiple inositol polyphosphate histidine phosphatase,...)
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Aliases for MINPP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Multiple Inositol-Polyphosphate Phosphatase 11 2 | | EC 3.1.3.623 8 | | MIPP1 2 3 | | HIPER12 5 | | Multiple Inositol Polyphosphate Histidine Phosphatase, 11 2 | | MINPP22 | | Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase2 3 | | Multiple Inositol Polyphosphate Phosphatase 12 | | Ins(1,3,4,5)P(4) 3-Phosphatase2 3 | | Multiple Inositol Polyphosphate Phosphatase 22 | | 2,3-Bisphosphoglycerate 3-Phosphatase2 3 | | EC 3.1.3.803 | | 2,3-BPG Phosphatase2 3 | | |
Export aliases for MINPP1 gene to outside databasesPrevious GC identifers: GC10P088146 GC10P088486 GC10P089395 GC10P088929 GC10P089254 GC10P082898 |
Summaries for MINPP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for MINPP1: This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositolphosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositolhexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activityformerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of theglycolytic pathway.(provided by RefSeq, Sep 2009) UniProtKB/Swiss-Prot: MINP1_HUMAN, Q9UNW1Function: Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositolpentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase,by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate withoutformation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification) Gene Wiki entry for MINPP1
|
Genomic Views for MINPP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MINPP1 gene promoter: AML1a Tal-1 Lmo2 Nkx2-5 E47 FOXL1 HEN1 POU2F1 POU2F1a Other transcription factors
Search SABiosciences Chromatin IP Primers for MINPP1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MINPP1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q23 Ensembl cytogenetic band: 10q23.2 HGNC cytogenetic band: 10q23MINPP1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P089264: view genomic region
(about GC identifiers)
Start:
|
89,264,223 bp from pter |
End:
|
89,313,218 bp from pter |
Size:
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48,996 bases |
Orientation:
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plus strand |
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Proteins for MINPP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: MINP1_HUMAN, Q9UNW1 (See
protein sequence)Recommended Name: Multiple inositol polyphosphate phosphatase 1 precursor Size: 487 amino acids; 55051 Da
Subcellular location: Endoplasmic reticulum lumen (By similarity)
Sequence caution: Sequence=BAD93056.1; Type=Erroneous initiation;
Secondary accessions: F5H683 O95172 O95286 Q59EJ2 Q9UGA3Alternative splicing: 4 isoforms: Q9UNW1-1 Q9UNW1-2 Q9UNW1-3 Q9UNW1-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MINPP1: NX_Q9UNW1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UNW1 3 DME Specific Peptides for MINPP1 (Q9UNW1)
MINPP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001171588.1 NP_001171589.1 NP_004888.2 ENSEMBL proteins: ENSP00000361064 ENSP00000361062 ENSP00000437823 Reactome Protein details: Q9UNW1 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MINPP1 for ontologies About GeneDecksing
MINPP1 Antibody Products: Assay Products for MINPP1: |
Protein
Domains / Families for MINPP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MINPP1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UNW1ProtoNet protein and cluster: Q9UNW1 1 Blocks protein family: IPB000560 Histidine acid phosphatase
UniProtKB/Swiss-Prot: MINP1_HUMAN, Q9UNW1Similarity: Belongs to the histidine acid phosphatase family. MINPP1 subfamily |
Function for MINPP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: MINP1_HUMAN, Q9UNW1Function: Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositolpentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase,by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate withoutformation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification)Catalytic activity: Myo-inositol hexakisphosphate + H(2)O = myo-inositol pentakisphosphate (mixed isomers) + phosphateCatalytic activity: 2,3-bisphospho-D-glycerate + H(2)O = 2-phospho-D-glycerate + phosphateBiophysicochemical properties: Kinetic parameters: KM=0.61 mM for 2,3-bisphosphoglycerate; Vmax=15.8 nmol/min/mg enzymewith 2,3-bisphospho-D-glycerate as substrate; Genatlas biochemistry entry for MINPP1:multiple inositol polyphosphate phosphatase 1,belonging to a distinct group of histidine phosphatase Enzyme Numbers (IUBMB): EC 3.1.3.621 2 EC 3.1.3.801
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MINPP1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MINPP1 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): MINPP1 (NM_004897) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MINPP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MINPP1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MINPP1 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003993 | acid phosphatase activity |
IEA | -- | | GO:0008969 | phosphohistidine phosphatase activity |
TAS | 10087200 | | GO:0030351 | inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity |
-- | -- | | GO:0030352 | inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity |
-- | -- | | GO:0034417 | bisphosphoglycerate 3-phosphatase activity |
IDA | 18413611 |
MINPP1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for MINPP1: Animal Models: Mouse knock-out Minpp1tm1Prr for MINPP1 1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Minpp1):
MINPP1 for phenotypes About GeneDecksing
|
Pathways & Interactions for MINPP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | | | 2 | Inositol phosphate metabolism | | | 3 | D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis | | | 4 | Rapoport-Luebering glycolytic shunt | | | 5 | Metabolism | |
Pathway sources See GeneCards unified pathways Show all pathways
5 BioSystems Pathways for MINPP1 
3
Reactome Pathways for MINPP1
1
Kegg Pathway (Kegg details for MINPP1):
MINPP1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MINPP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/30 Interacting proteins for MINPP1 (Q9UNW13 ENSP000003610644) via UniProtKB, MINT, STRING, and/or I2D (see all 30)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
MINPP1 for ontologies About GeneDecksing
|
Drugs & Compounds for MINPP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MINPP1 for compounds About GeneDecksing
Browse Tocris compounds for MINPP1
5 HMDB Compounds for MINPP1 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Inositol 1,3,4,5-tetraphosphate | 1,3,4,5-tetrakis(dihydrogen phosphate) myo-Inositol (see all 16) | 102850-29-3 | -- | | Inositol 1,4,5-trisphosphate | 1D-myo-Inositol 1,4,5-trisphosphate (see all 4) | 88269-39-0 | -- | | Myo-inositol hexakisphosphate | 1D-myo-Inositol 1,2,3,4,5,6-hexakisphosphate (see all 9) | 83-86-3 | -- | | Phosphate | NFB Orthophosphate (see all 13) | 14265-44-2 | -- | | Water | Dihydrogen oxide (see all 2) | 7732-18-5 | -- | 2 Novoseek chemical compound relationships for MINPP1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| phytate |
67.7 |
2 |
15979280 (2) |
| inositol |
54.8 |
1 |
9923613 (1) |
Search CenterWatch for drugs/clinical trials and news about MINPP1 / MINP1 
|
Transcripts for MINPP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for MINPP1 gene (3 alternative transcripts): NM_001178117.1 NM_001178118.1 NM_004897.4 Unigene Cluster for MINPP1: Multiple inositol-polyphosphate phosphatase 1 Hs.121260 [show with all ESTs]Unigene Representative Sequence: NM_0048974 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371996(uc001keu.3 uc009xtf.2) ENST00000371994(uc001kev.3) ENST00000472891 ENST00000536010(uc021pvv.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MINPP1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MINPP1 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): MINPP1 (NM_004897) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MINPP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MINPP1  |
Additional cDNA sequence: AB209819.1 AF046914.1 AF084943.1 AF084944.1 AK304624.1 AK309176.1 AK312937.1 AL050356.1 AY358938.1 BC032504.1 6 DOTS entries: DT.410746 DT.100817951 DT.100817947 DT.100817952 DT.100817954 DT.121249170 24/117 AceView cDNA sequences (see all 117): AW961214 AF084944 CR595009 BU625626 BX351615 BX396922 BQ002769 AA666012 Z44288 AA315402 BQ004246 BC032504 F10100 BQ575074 BF968487 BQ632253 BQ003601 AU279759 AW204904 F12482 NM_004897 CA442671 BE048544 Z40249 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for MINPP1 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for MINPP1
|
Expression for MINPP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MINPP1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AAATGTAAGA
About this image See MINPP1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MINPP1
SOURCE GeneReport for Unigene cluster: Hs.121260 UniProtKB/Swiss-Prot: MINP1_HUMAN, Q9UNW1Tissue specificity: Widely expressed with highest levels in kidney, liver and placenta SABiosciences Custom PCR Arrays for MINPP1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MINPP1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MINPP1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MINPP1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MINPP1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MINPP1 |
Orthologs for MINPP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MINPP1 gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Minpp11 , 5 |
multiple inositol polyphosphate histidine phosphatase more1, 5 |
81.7(n)1 83.16(a)1 |
  |
19 (27.25 cM)5 173301 NM_010799.21 NP_034929.11 324857695 |
chicken (Gallus gallus) |
Aves |
MINPP11 |
multiple inositol-polyphosphate phosphatase 1 |
66.12(n) 60.84(a) |
  |
395356 NM_204644.1 NP_989975.1 |
lizard (Anolis carolinensis) |
Reptilia |
MINPP16 |
-- |
54(a) |
1 ↔ 1 |
GL343246.1(1154804-1173426) |
zebrafish (Danio rerio) |
Actinopterygii |
zgc560802 |
similar to multiple inositol polyphosphate histidine more |
74.82(n) |
  |
394075 BC047824.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Mipp21 , 3 |
inositol/phosphatidylinositol phosphatase3 Multiple inositol polyphosphate phosphatase 21 |
26(a)3 42.25(n)1 30.27(a)1 |
  |
5D43 315441 NM_078500.31 NP_511055.11 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT1G098701 |
histidine acid phosphatase-like protein |
42.09(n) 28.91(a) |
  |
837519 NM_100861.3 NP_563856.1 |
rice (Oryza sativa) |
Liliopsida |
Os03g08181001 |
hypothetical protein |
43.4(n) 28.96(a) |
  |
4334577 NM_001058240.1 NP_001051705.1 |
ENSEMBL Gene Tree for MINPP1 (if available) TreeFam Gene Tree for MINPP1 (if available)  |
Paralogs for MINPP1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for MINPP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 10 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for MINPP1 (89264223 - 89313218 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 13 variations for MINPP1 7 CNVs: 58478 58477 65747 2885 65750 65749 3815 6 Indels: 85421 39773 75350 75349 85422 75348 Human Gene Mutation Database (HGMD): MINPP1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MINPP1 |
|
Disorders
/ Diseases for MINPP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MINPP1 for disorders About GeneDecksing
OMIM gene information: 605391 OMIM disorders: 188470 UniProtKB/Swiss-Prot: MINP1_HUMAN, Q9UNW1
Note=Defects in MINPP1 may be involved in follicular thyroid tumors development 12 diseases for MINPP1: About MalaCardsbannayan-riley-ruvalcaba syndrome ruvalcaba syndrome cowden disease follicular thyroid carcinoma fanconi's anemia thyroid carcinoma thyroiditis anemia alzheimer's disease carcinoma prostate cancer prostatitis 1 disease from the University of Copenhagen DISEASES database for MINPP1:Bannayan-Riley-Ruvalcaba syndrome 1 Novoseek disease relationship for MINPP1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
5 |
11297621 (3) |
Human Genome Epidemiology (HuGE) Navigator: MINPP1 (3 documents) Export disorders for MINPP1 gene to outside databases
|
Publications for MINPP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MINPP1 gene, integrated from 9 sources (see all 26): (articles sorted by number of sources associating them with MINPP1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. (PubMed id 10087200)1, 2, 3, 9 Chi H.... Reynolds P.R. (1999)
- Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas. (PubMed id 11297621)1, 2, 9 Gimm O.... Eng C. (2001)
- The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up- regulated during endochondral ossification. (PubMed id 9923613)1, 2, 9 Caffrey J.J.... Shears S.B. (1999)
- Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. (PubMed id 18413611)1, 2 Cho J....Shears S.B. (2008)
- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas. (PubMed id 11536049)1, 9 VanHouten J.N....Asch B.B. (2001)
|
External Searches for MINPP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MINPP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MINPP1 gene
(According to HUGE)
About This Section
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Specialized Databases showing MINPP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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About This Section
| Patent Information for MINPP1 gene: Search GeneIP for patents involving MINPP1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for MINPP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | OriGene Antibodies for MINPP1 | | OriGene shRNA RFP for MINPP1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MINPP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MINPP1 | | OriGene Protein Over-expression Lysate for MINPP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for MINPP1 | | OriGene 3'-UTR Clone for MINPP1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MINPP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MINPP1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for MINPP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for MINPP1 | | OriGene Custom Protein Services for MINPP1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MINPP1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MINPP1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MINPP1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MINPP1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MINPP1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MINPP1 |
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| | | Search Tocris compounds for MINPP1 |
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 | | MINPP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MINPP1 |
|  |  |  | | | ThermoFisher Antibody for MINPP1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MINPP1 |
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