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Aliases for MINOS1-NBL1 Gene

Aliases for MINOS1-NBL1 Gene

  • MINOS1-NBL1 Readthrough 2 3 5
  • C1orf151-NBL1 3

External Ids for MINOS1-NBL1 Gene

Previous GeneCards Identifiers for MINOS1-NBL1 Gene

  • GC01P019925

Summaries for MINOS1-NBL1 Gene

Entrez Gene Summary for MINOS1-NBL1 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring chromosome 1 open reading frame 151 (GeneID 440574) and neuroblastoma suppressor of tumorigenicity 1 (GeneID 4681) genes on chromosome 1. The read-through transcripts produce at least two proteins, each of which share identity with proteins translated from the downstream neuroblastoma suppressor of tumorigenicity 1 locus. [provided by RefSeq, Feb 2011]

GeneCards Summary for MINOS1-NBL1 Gene

MINOS1-NBL1 (MINOS1-NBL1 Readthrough) is a Protein Coding gene. Among its related pathways are TGF-beta signaling pathway (KEGG). GO annotations related to this gene include protein homodimerization activity and morphogen activity. An important paralog of this gene is NBL1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MINOS1-NBL1 Gene

Genomics for MINOS1-NBL1 Gene

Regulatory Elements for MINOS1-NBL1 Gene

Enhancers for MINOS1-NBL1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MINOS1-NBL1 on UCSC Golden Path with GeneCards custom track

Promoters for MINOS1-NBL1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MINOS1-NBL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MINOS1-NBL1 Gene

Chromosome:
1
Start:
19,596,977 bp from pter
End:
19,658,456 bp from pter
Size:
61,480 bases
Orientation:
Plus strand

Genomic View for MINOS1-NBL1 Gene

Genes around MINOS1-NBL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MINOS1-NBL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MINOS1-NBL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MINOS1-NBL1 Gene

Proteins for MINOS1-NBL1 Gene

  • Protein details for MINOS1-NBL1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    R4GMM1
    Recommended name:
    Protein MINOS1-NBL1
    Protein Accession:
    R4GMM1

    Protein attributes for MINOS1-NBL1 Gene

    Size:
    46 amino acids
    Molecular mass:
    5154 Da
    Quaternary structure:
    No Data Available
  • Protein details for MINOS1-NBL1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    R4GMY4
    Recommended name:
    MICOS complex subunit MIC10
    Protein Accession:
    R4GMY4

    Protein attributes for MINOS1-NBL1 Gene

    Size:
    70 amino acids
    Molecular mass:
    7931 Da
    Quaternary structure:
    • Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
  • Protein details for MINOS1-NBL1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    R4GNA1
    Recommended name:
    MICOS complex subunit MIC10
    Protein Accession:
    R4GNA1

    Protein attributes for MINOS1-NBL1 Gene

    Size:
    71 amino acids
    Molecular mass:
    8074 Da
    Quaternary structure:
    • Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.

neXtProt entry for MINOS1-NBL1 Gene

Proteomics data for MINOS1-NBL1 Gene at MOPED

Post-translational modifications for MINOS1-NBL1 Gene

No Post-translational modifications

Other Protein References for MINOS1-NBL1 Gene

No data available for DME Specific Peptides for MINOS1-NBL1 Gene

Domains & Families for MINOS1-NBL1 Gene

Protein Domains for MINOS1-NBL1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MINOS1-NBL1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MINOS1-NBL1 Gene

Function for MINOS1-NBL1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MINOS1-NBL1 Gene

Localization for MINOS1-NBL1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MINOS1-NBL1 Gene

Pathways & Interactions for MINOS1-NBL1 Gene

SuperPathways for MINOS1-NBL1 Gene

genes like me logo Genes that share pathways with MINOS1-NBL1: view

Pathways by source for MINOS1-NBL1 Gene

1 KEGG pathway for MINOS1-NBL1 Gene

Interacting Proteins for MINOS1-NBL1 Gene

Gene Ontology (GO) - Biological Process for MINOS1-NBL1 Gene

None

No data available for SIGNOR curated interactions for MINOS1-NBL1 Gene

Drugs & Compounds for MINOS1-NBL1 Gene

No Compound Related Data Available

Transcripts for MINOS1-NBL1 Gene

mRNA/cDNA for MINOS1-NBL1 Gene

(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MINOS1-NBL1 Gene

No ASD Table

Relevant External Links for MINOS1-NBL1 Gene

GeneLoc Exon Structure for
MINOS1-NBL1
ECgene alternative splicing isoforms for
MINOS1-NBL1

Expression for MINOS1-NBL1 Gene

mRNA expression in normal human tissues for MINOS1-NBL1 Gene

genes like me logo Genes that share expression patterns with MINOS1-NBL1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MINOS1-NBL1 Gene

Orthologs for MINOS1-NBL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MINOS1-NBL1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NBL1 35
  • 89.12 (n)
  • 92.11 (a)
-- 36
  • 95 (a)
OneToMany
dog
(Canis familiaris)
Mammalia NBL1 35
  • 91.58 (n)
  • 96.15 (a)
-- 36
  • 98 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Nbl1 35
  • 89.51 (n)
  • 93.82 (a)
Nbl1 36
  • 94 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Nbl1 35
  • 88.39 (n)
  • 92.7 (a)
chicken
(Gallus gallus)
Aves NBL1 35
  • 79.31 (n)
  • 79.19 (a)
NBL1 36
  • 71 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 61 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia nbl1 35
  • 80.15 (n)
  • 80.15 (a)
zebrafish
(Danio rerio)
Actinopterygii nbl1 35
  • 69.39 (n)
  • 68.71 (a)
NBL1 36
  • 52 (a)
OneToMany
Species with no ortholog for MINOS1-NBL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MINOS1-NBL1 Gene

ENSEMBL:
Gene Tree for MINOS1-NBL1 (if available)
TreeFam:
Gene Tree for MINOS1-NBL1 (if available)

Paralogs for MINOS1-NBL1 Gene

Paralogs for MINOS1-NBL1 Gene

(3) SIMAP similar genes for MINOS1-NBL1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with MINOS1-NBL1: view

Variants for MINOS1-NBL1 Gene

Sequence variations from dbSNP and Humsavar for MINOS1-NBL1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs2792060 -- 19,631,045(+) AACAG(A/T)TTTTG intron-variant
rs2792061 -- 19,632,235(+) TAGCC(A/G)ACATA intron-variant
rs2792062 -- 19,633,285(+) CCCTG(C/G)GTCAC intron-variant
rs2792063 -- 19,633,575(+) CAGAC(A/G)TGACT intron-variant
rs6426816 -- 19,633,013(+) AGCCT(A/G)GAGTA intron-variant

Variation tolerance for MINOS1-NBL1 Gene

Gene Damage Index Score: 0.66; 14.11% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MINOS1-NBL1 Gene

HapMap Linkage Disequilibrium report
MINOS1-NBL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MINOS1-NBL1 Gene

Disorders for MINOS1-NBL1 Gene

Relevant External Links for MINOS1-NBL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MINOS1-NBL1

No disorders were found for MINOS1-NBL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MINOS1-NBL1 Gene

Publications for MINOS1-NBL1 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 67

Products for MINOS1-NBL1 Gene

Sources for MINOS1-NBL1 Gene

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