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Aliases for MINOS1 Gene

Aliases for MINOS1 Gene

  • Mitochondrial Inner Membrane Organizing System 1 2 3
  • Mitochondrial Inner Membrane Organizing System Protein 1 3 4
  • C1orf151 3 4
  • Chromosome 1 Open Reading Frame 151 2
  • MICOS Complex Subunit MIC10 3
  • UPF0327 Protein C1orf151 3
  • RP5-1056L3.2 3
  • MIC10 4
  • MIO10 3

External Ids for MINOS1 Gene

Previous HGNC Symbols for MINOS1 Gene

  • C1orf151

Previous GeneCards Identifiers for MINOS1 Gene

  • GC01P019924

Summaries for MINOS1 Gene

GeneCards Summary for MINOS1 Gene

MINOS1 (Mitochondrial Inner Membrane Organizing System 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MINOS1 Gene

  • Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MINOS1 Gene

Genomics for MINOS1 Gene

Genomic Location for MINOS1 Gene

Start:
19,596,977 bp from pter
End:
19,629,821 bp from pter
Size:
32,845 bases
Orientation:
Plus strand

Genomic View for MINOS1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MINOS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MINOS1 Gene

No data available for Regulatory Elements for MINOS1 Gene

Proteins for MINOS1 Gene

  • Protein details for MINOS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TGZ0-MIC10_HUMAN
    Recommended name:
    MICOS complex subunit MIC10
    Protein Accession:
    Q5TGZ0
    Secondary Accessions:
    • Q96G68

    Protein attributes for MINOS1 Gene

    Size:
    78 amino acids
    Molecular mass:
    8808 Da
    Quaternary structure:
    • Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MINOS1/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27 and IMMT/MIC60. The complex associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2, and with HSPA9.
    SequenceCaution:
    • Sequence=AAH09927.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for MINOS1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MINOS1 Gene

Proteomics data for MINOS1 Gene at MOPED

Post-translational modifications for MINOS1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MINOS1 Gene

No data available for DME Specific Peptides for MINOS1 Gene

Domains for MINOS1 Gene

Protein Domains for MINOS1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5TGZ0

UniProtKB/Swiss-Prot:

MIC10_HUMAN :
  • Q5TGZ0
Family:
  • Belongs to the MICOS complex subunit Mic10 family.
genes like me logo Genes that share domains with MINOS1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for MINOS1 Gene

Function for MINOS1 Gene

Molecular function for MINOS1 Gene

UniProtKB/Swiss-Prot Function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

Gene Ontology (GO) - Molecular Function for MINOS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MINOS1: view

miRNA for MINOS1 Gene

miRTarBase miRNAs that target MINOS1

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MINOS1 Gene

Localization for MINOS1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MINOS1 Gene

Mitochondrion inner membrane; Single-pass membrane protein. Note=The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (PubMed:22114354). {ECO:0000250, ECO:0000269 PubMed:22114354}.

Gene Ontology (GO) - Cellular Components for MINOS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA --
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MINOS1: view

No data available for Subcellular locations from COMPARTMENTS for MINOS1 Gene

Pathways for MINOS1 Gene

SuperPathways for MINOS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MINOS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with MINOS1: view

No data available for Pathways by source for MINOS1 Gene

Transcripts for MINOS1 Gene

Unigene Clusters for MINOS1 Gene

Mitochondrial inner membrane organizing system 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MINOS1 Gene

No ASD Table

Relevant External Links for MINOS1 Gene

GeneLoc Exon Structure for
MINOS1
ECgene alternative splicing isoforms for
MINOS1

Expression for MINOS1 Gene

mRNA expression in normal human tissues for MINOS1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MINOS1 Gene

SOURCE GeneReport for Unigene cluster for MINOS1 Gene Hs.466662

genes like me logo Genes that share expressions with MINOS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MINOS1 Gene

Orthologs for MINOS1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MINOS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MINOS1 35
  • 99.05 (n)
  • 100 (a)
MINOS1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MINOS1 35
  • 89.78 (n)
  • 94.67 (a)
dog
(Canis familiaris)
Mammalia MINOS1 35
  • 94.67 (n)
  • 94.67 (a)
MINOS1 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Minos1 35
  • 88.89 (n)
  • 93.33 (a)
Minos1 16
Minos1 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MINOS1 36
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MINOS1 36
  • 68 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100361944 35
  • 88 (n)
  • 90.67 (a)
chicken
(Gallus gallus)
Aves MINOS1 35
  • 81.08 (n)
  • 82.43 (a)
MINOS1 36
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100135143 35
  • 72.97 (n)
  • 78.38 (a)
zebrafish
(Danio rerio)
Actinopterygii minos1 35
  • 66.67 (n)
  • 69.57 (a)
minos1 36
  • 66 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F54A3.5 36
  • 40 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 38
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5565 36
  • 27 (a)
OneToOne
Species with no ortholog for MINOS1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MINOS1 Gene

ENSEMBL:
Gene Tree for MINOS1 (if available)
TreeFam:
Gene Tree for MINOS1 (if available)

Paralogs for MINOS1 Gene

Selected SIMAP similar genes for MINOS1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MINOS1: view

No data available for Paralogs for MINOS1 Gene

Variants for MINOS1 Gene

Relevant External Links for MINOS1 Gene

HapMap Linkage Disequilibrium report
MINOS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MINOS1 Gene

Disorders for MINOS1 Gene

No disorders were found for MINOS1 Gene.

No data available for UniProtKB/Swiss-Prot for MINOS1 Gene

Publications for MINOS1 Gene

  1. Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. (PMID: 21944719) von der Malsburg K. … van der Laan M. (Dev. Cell 2011) 2 3
  2. MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. (PMID: 22114354) Alkhaja A.K. … Deckers M. (Mol. Biol. Cell 2012) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PMID: 16712791) Wang A.G. … Kim N.S. (Biochem. Biophys. Res. Commun. 2006) 3

Products for MINOS1 Gene

  • antibodies-online peptides for MINOS1
  • antibodies-online antibodies for MINOS1
  • antibodies-online kits for MINOS1

Sources for MINOS1 Gene

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