Aliases for MIER1 Gene
External Ids for MIER1 Gene
This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]
GeneCards Summary for MIER1 Gene
MIER1 (Mesoderm Induction Early Response 1, Transcriptional Regulator) is a Protein Coding gene. GO annotations related to this gene include chromatin binding and signal transducer activity. An important paralog of this gene is MIER2.
UniProtKB/Swiss-Prot for MIER1 Gene
Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing.