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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MICU1 Gene

protein-coding   GIFtS: 44
GCID: GC10M074128

mitochondrial calcium uptake 1

(Previous name: calcium binding atopy-related autoantigen 1 )
(Previous symbol: CBARA1)
 Explore 4 diseases affiliated with
MICU1 via our new
 Human Malady Compendium 
Biological research products
for MICU1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Mitochondrial Calcium Uptake 11 2     Ara CALC2 3
CALC1 2 3     FLJ126841
CBARA11 2 3     Calcium Binding Atopy-Related Autoantigen 11
EFHA31 2     Atopy Related Autoantigen2
Atopy-Related Autoantigen CALC2 3     Calcium Uptake Protein 1, Mitochondrial2
Calcium-Binding Atopy-Related Autoantigen 12 3     Allergen Hom S 43

External Ids:    HGNC: 15301   Entrez Gene: 103672   Ensembl: ENSG000001077457   OMIM: 6050845   UniProtKB: Q9BPX63   

Export aliases for MICU1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MICU1_HUMAN, Q9BPX6
Function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when
cytoplasmic calcium is low. Acts as a gatekeeper that senses calcium level via its EF-hand domains and sets a
threshold for mitochondrial calcium uptake by MCU, thereby preventing mitochondrial calcium overload. Regulates
glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Induces
T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG

Gene Wiki entry for MICU1 (CBARA1)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for MICU1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMICU1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MICU1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MICU1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.1   HGNC cytogenetic band: 10q22.1

MICU1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MICU1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M074128:  view genomic region     (about GC identifiers)

Start:
74,127,098 bp from pter      End:
74,385,899 bp from pter
Size:
258,802 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MICU1_HUMAN, Q9BPX6 (See protein sequence)
Recommended Name: Calcium uptake protein 1, mitochondrial precursor  
Size: 476 amino acids; 54351 Da
Subunit: Interacts with MCU
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein
Allergen: Causes an allergic reaction in human. Binds to IgE from atopic dermatitis (AD) patients. Identified as an IgE
autoantigen in atopic dermatitis (AD) patients with severe skin manifestations
Sequence caution: Sequence=BAB14187.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAA76830.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the
N-terminal part;
Secondary accessions: A8MV96 B3KN20 B4DJH9 B4DPI1 B5MBY3 D3YTJ3 O75785 Q9H9N6 Q9UFX0
Alternative splicing: 5 isoforms:  Q9BPX6-1   Q9BPX6-2   Q9BPX6-3   Q9BPX6-4   Q9BPX6-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MICU1: NX_Q9BPX6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BPX6

  • MICU1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001182447.1  NP_001182448.1  NP_006068.2  

    ENSEMBL proteins: 
     ENSP00000354415   ENSP00000432492   ENSP00000381745   ENSP00000384068   ENSP00000402470  
     ENSP00000381747  

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    Uscn Proteins for MICU1

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular TAS9806765
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IDA--
    GO:0016021integral to membrane ----
    GO:0032592integral to mitochondrial membrane IDA--


    MICU1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MICU1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry Q9BPX6

    ProtoNet protein and cluster: Q9BPX6

    UniProtKB/Swiss-Prot: MICU1_HUMAN, Q9BPX6
    Domain: The EF-hand domains have high affinity for calcium and act as sensors of mitochondrial matrix calcium levels
    (PubMed:23101630)
    Similarity: Belongs to the MICU1 family
    Similarity: Contains 2 EF-hand domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MICU1_HUMAN, Q9BPX6
    Function: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when
    cytoplasmic calcium is low. Acts as a gatekeeper that senses calcium level via its EF-hand domains and sets a
    threshold for mitochondrial calcium uptake by MCU, thereby preventing mitochondrial calcium overload. Regulates
    glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Induces
    T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG

    miRNA
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    hsa-miR-3689b hsa-miR-146a hsa-miR-3689a-5p hsa-miR-3689e hsa-miR-544b hsa-miR-214 hsa-miR-518a-5p hsa-miR-589
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IDA--
    GO:0005515protein binding IPI--


    MICU1 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for MICU1:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa  Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MICU1

    5 Interacting proteins for MICU1 (Q9BPX63) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BABAM1Q9NWV83I2D: score=2 
    SQSTM1Q135013I2D: score=2 
    ATG2AQ2TAZ03I2D: score=1 
    CLN3Q132863I2D: score=1 
    SLX4Q8IY923I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006851mitochondrial calcium ion transport IMP--
    GO:0006952defense response TAS9806765
    GO:0051560mitochondrial calcium ion homeostasis IMP--
    GO:0051561elevation of mitochondrial calcium ion concentration ----
    GO:0070509calcium ion import IDA--


    MICU1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MICU1
    Search CenterWatch for drugs/clinical trials and news about MICU1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MICU1 gene (3 alternative transcripts): 
    NM_001195518.1  NM_001195519.1  NM_006077.3  

    Unigene Cluster for MICU1:

    Mitochondrial calcium uptake 1
    Hs.524367  [show with all ESTs]
    Unigene Representative Sequence: NM_006077
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361114(uc010qjx.2 uc010qjw.2) ENST00000476605(uc009xqo.2)
    ENST00000489666 ENST00000398761(uc001jtb.2) ENST00000401998 ENST00000418483
    ENST00000398763

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    hsa-miR-3689b hsa-miR-146a hsa-miR-3689a-5p hsa-miR-3689e hsa-miR-544b hsa-miR-214 hsa-miR-518a-5p hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmidMICU1 3' UTR sequence
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    Additional cDNA sequence: 

    AK022697.1 AK023318.1 AK225298.1 AK225695.1 AK296086.1 AK298347.1 AL117423.1 BC004190.2 
    BC004216.2 BC016641.1 Y17711.1 

    15 DOTS entries:

    DT.101963475  DT.80101824  DT.121222050  DT.95210823  DT.100813495  DT.95210831  DT.121221895  DT.100813489 
    DT.100813490  DT.87005401  DT.95216707  DT.121221924  DT.95210837  DT.95210870  DT.99943725 

    24/324 AceView cDNA sequences (see all 324):

    BM826024 BM666296 BM711296 AW085844 AI470013 CB143744 BM743254 AA989138 
    BF970142 CR615459 BU186079 AA250785 BC004190 CR616781 AI016960 BM835430 
    AA716132 T32756 AA917754 AI206577 BQ267875 CA313400 BM836611 BC016641 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MICU1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                          -                 -                                   -               
    SP2:                                            -                                                   
    SP3:                                                                                                
    SP4:                                                                                                


    ECgene alternative splicing isoforms for MICU1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MICU1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCCCTGCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MICU1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MICU1

    SOURCE GeneReport for Unigene cluster: Hs.524367

    UniProtKB/Swiss-Prot: MICU1_HUMAN, Q9BPX6
    Tissue specificity: Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal
    endothelial cells

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MICU1 gene from 9/27 species (see all 27)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Micu11 , 5 mitochondrial calcium uptake 11, 5 86.88(n)1
    93.05(a)1
      10 (29.60 cM)5
    2160011  NM_144822.21  NP_659071.11 
     597024775 
    chicken
    (Gallus gallus)
    Aves MICU11 mitochondrial calcium uptake 1 77.82(n)
    81.47(a)
      769141  XM_001231721.2  XP_001231722.2 
    lizard
    (Anolis carolinensis)
    Reptilia MICU16
    --
    79(a)
    1 ↔ 1
    3(51988964-52095970)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.217022 Xenopus laevis transcribed sequence with weak similarity more 79.62(n)    CA788097.1 
    zebrafish
    (Danio rerio)
    Actinopterygii micu11 mitochondrial calcium uptake 1 71.08(n)
    76.47(a)
      561210  NM_001083833.1  NP_001077302.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG44951 CG4495 59.14(n)
    55.84(a)
      33999  NM_001103640.1  NP_001097110.1 
    worm
    (Caenorhabditis elegans)
    Secernentea micu-11 Protein MICU-1 55.17(n)
    51.6(a)
      178287  NM_070154.3  NP_502555.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G320601 EF-hand, calcium binding motif-containing protein 46.93(n)
    33.05(a)
      829337  NM_119358.3  NP_194934.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g06130001 hypothetical protein 45.58(n)
    33.78(a)
      4329968  NM_001053952.1  NP_001047417.1 


    ENSEMBL Gene Tree for MICU1 (if available)
    TreeFam Gene Tree for MICU1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MICU1 gene
    EFHA12  EFHA22  

    MICU1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4090 NCBI SNPs in MICU1 are shown (see all 4090    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1903996471,2
    --74126719(+) ATTGCA/GCCACT 3 -- int10--------
    rs1463155231,2
    --74126733(+) TTCCAC/GCCTGG 3 -- int10--------
    rs1819363011,2
    --74126758(+) CCCTGC/TCTCAA 3 -- int10--------
    rs1144117381,2
    --74126914(+) CTGTGC/TGGGGA 3 -- int11Minor allele frequency- T:0.01WA 118
    rs412822681,2
    --74127076(+) GAGGAA/CCCTAA 3 -- int10--------
    rs1396210211,2
    --74127096(+) GACAGA/GGAACT 3 -- ut310--------
    rs1442945891,2
    --74127157(+) TTTAAC/GACAGA 3 -- ut310--------
    rs1507602041,2
    --74127178(+) GCTCTC/GAGCCA 3 -- ut310--------
    rs136881,2
    C,--74127221(+) NNNNGG/ACACTT 3 -- ut314Minor allele frequency- A:0.03MN NA 308
    rs1391544631,2
    --74127276(+) TCACAA/CTGGAG 3 -- ut310--------

    HapMap Linkage Disequilibrium report for MICU1 (74127098 - 74377098 bp, first 250kb of MICU1)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MICU1: --

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MICU1 for disorders           About GeneDecksing

    OMIM gene information: 605084    OMIM disorders: --

    4 diseases for MICU1:    About MalaCards
    atopy    atopic dermatitis    dermatitis    alzheimer's disease


    Export disorders for MICU1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MICU1 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with MICU1)
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    1. MICU1 encodes a mitochondrial EF hand protein require d for Ca(2+) uptake. (PubMed id 20693986)1, 2, 3 Perocchi F....Mootha V.K. (2010)
    2. Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients. (PubMed id 9806765)1, 2, 3 Natter S.... Valenta R. (1998)
    3. MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival. (PubMed id 23101630)1, 2 Mallilankaraman K.... Madesh M. (2012)
    4. Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic beta-cells. (PubMed id 22904319)1, 2 Alam M.R.... Graier W.F. (2012)
    5. Integrative genomics identifies MCU as an essential c omponent of the mitochondrial calcium uniporter. (PubMed id 21685886)1, 2 Baughman J.M....Mootha V.K. (2011)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    8. MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism. (PubMed id 23178883)2 Mallilankaraman K.... Madesh M. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10367 HGNC: 1530 AceView: CBARA1 Ensembl:ENSG00000107745 euGenes: HUgn10367
    ECgene: MICU1 H-InvDB: MICU1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MICU1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MICU1 gene:
    Search GeneIP for patents involving MICU1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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