Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



MICD Gene

pseudogene   GIFtS: 17
GCID: GC06M030026

MHC Class I Polypeptide-Related Sequence D (Pseudogene)

(Previous names: MHC class I polypeptide-related sequence D, MHC class I...)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
MHC Class I Polypeptide-Related Sequence D (Pseudogene)1 2     FBN15
MHC Class I Polypeptide-Related Sequence D1     GPHYSD25
MHC Class I Polypeptide-Related Sequence D, Pseudogene1     MFS15
PERB11.42     SSKS5
ACECTOL15     WMS25

External Ids:    HGNC: 70931   Entrez Gene: 42792   Ensembl: ENSG000002293907   OMIM: 1347975   

Export aliases for MICD gene to outside databases

Previous GC identifers: GC06U990082 GC06M030043 GC06M030046 GC06M029939 GC06M029940 GC06Mj29929 GC06M029943 GC06M029957


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for MICD Gene:
MICD (MHC class I polypeptide-related sequence D (pseudogene)) is a pseudogene. Diseases associated with MICD include multiple sclerosis.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Search for regulatory transcription factor binding sites for MICD
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMICD promoter sequence
   Search Chromatin IP Primers for MICD

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MICD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21.3

MICD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MICD gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M030026:  view genomic region     (about GC identifiers)

Start:
29,938,149 bp from pter      End:
29,943,522 bp from pter
Size:
5,374 bases      Orientation:
minus strand

6 alternative locations:
Chr6-,NT_167245 1,231,498-1,236,854      Chr6-,NT_167246 1,236,726-1,242,098      Chr6-,NT_113891.2 1,449,867-1,455,223     
Chr6-,NT_167248 1,230,951-1,236,312      Chr6-,NT_167247 1,320,000-1,325,381      Chr6-,NT_167249 1,267,465-1,272,841     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB: --


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:
     Genatlas biochemistry entry for MICD:
MHC class I,chain-related gene D

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MICD
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MICD

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MICD
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MICD

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat MICD using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate MICD
SwitchGear 3'UTR luciferase reporter plasmidMICD 3' UTR sequence
Inhib. RNA
Products:
    
Browse OriGene RNAi
Predesigned siRNA for gene silencing in human, mouse, rat MICD

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for MICD

Clone
Products:
     
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for MICD
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MICD
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MICD

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for MICD
Browse ESI BIO Cell Lines and PureStem Progenitors for MICD 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MICD


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus
  --

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for MICD (see all 13)
    MAPK Signaling
Molecular Mechanisms of Cancer
PTEN Pathway
Transendothelial Migration of Leukocytes
UPA-UPAR Pathway


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MICD
Interactions:

    Search GeneGlobe Interaction Network for MICD

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MICD



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000413248
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat MICD using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate MICD
SwitchGear 3'UTR luciferase reporter plasmidMICD 3' UTR sequence
Inhib. RNA
Products:
     
Browse OriGene RNAi
Predesigned siRNA for gene silencing in human, mouse, rat MICD
Clone
Products:
     
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for MICD
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MICD
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MICD
Primer
Products:
    
Browse OriGene qPCR
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MICD
  QuantiTect SYBR Green Assays in human, mouse, rat MICD
  QuantiFast Probe-based Assays in human, mouse, rat MICD

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

MICD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
MICD Expression
About this image

MICD Protein expression data from MOPED1, PaxDb2 and MaxQB3 --
    Custom PCR Arrays for MICD
Primer
Products:
Browse OriGene qPCR
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MICD
QuantiTect SYBR Green Assays in human, mouse, rat MICD
QuantiFast Probe-based Assays in human, mouse, rat MICD
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MICD

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus
  --

ENSEMBL Gene Tree for MICD (if available)
TreeFam Gene Tree for MICD (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus
Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing MICD
DNA2.0 Custom Variant and Variant Library Synthesis for MICD

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 134797   
OMIM disorders: 154700  129600  604308  608328  184900  102370  614185  
1 disease for MICD:    About MalaCards
multiple sclerosis


MICD for disorders           About GeneDecksing

Genetic Association Database (GAD): MICD
Human Genome Epidemiology (HuGE) Navigator: MICD (1 document)

Export disorders for MICD gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for MICD gene integrated from 10 sources:
(articles sorted by number of sources associating them with MICD)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. (PubMed id 20593013)1, 4 Cree B.A.... . (PLoS ONE 2010)
  2. Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region. (PubMed id 10557312)1, 3 Shiina T....Inoko H. (Proc. Natl. Acad. Sci. U.S.A. 1999)
  3. A second lineage of mammalian major histocompatibility complex class I genes. (PubMed id 8022771)1, 3 Bahram S.... Spies T. (Proc. Natl. Acad. Sci. U.S.A. 1994)
  4. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with BehAset's disease. (PubMed id 20622878)4 Remmers E.F....GA1l A. (Nat. Genet. 2010)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 4279 HGNC: 7093 Ensembl:ENSG00000229390 euGenes: HUgn4279 ECgene: MICD
H-InvDB: MICD

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for MICD Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for MICD gene:
Search GeneIP for patents involving MICD

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   Browse OriGene RNAi products  
 Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
 OriGene Custom Mass Spec   Browse OriGene clones  
 Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for MICD   OriGene Custom Protein Services for MICD  

 
 
 Block miRNA regulation of human, mouse, rat MICD using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MICD
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MICD Predesigned siRNA for gene silencing in human, mouse, rat MICD
 QuantiFast Probe-based Assays in human, mouse, rat MICD QuantiTect SYBR Green Assays in human, mouse, rat MICD
 Custom PCR Arrays for MICD Search Chromatin IP Primers for MICD
 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MICD Search GeneGlobe Interaction Network for MICD
 Search Regulatory tfbs for MICD
 GenScript Custom Purified and Recombinant Proteins Services for MICD GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for MICD
 GenScript Custom Assay Services for MICD GenScript Custom overexpressing Cell Line Services for MICD
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for MICD
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Biologicals
 Novus Tissue Slides
 Search for Antibodies for MICD at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for MICD
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for MICD
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MICD
 SwitchGear 3'UTR luciferase reporter plasmids for MICD
 SwitchGear Promoter luciferase reporter plasmids for MICD
 Search ThermoFisher Antibodies for MICD
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MICD
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MICD
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MICD
 Search LSBio for Antibodies for MICD
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      MICD gene at Home site.
Version: 3.12.130 7 July 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4