Aliases for MICALL2 Gene
GeneCards Summary for MICALL2 Gene
MICALL2 (MICAL-Like 2) is a Protein Coding gene. GO annotations related to this gene include actin filament binding and filamin binding. An important paralog of this gene is SMTNL2.
UniProtKB/Swiss-Prot for MICALL2 Gene
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).