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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MICALL1 Gene

protein-coding GIFtS: 48
GCID: GC22P038301

MICAL-like 1

Search for MICALL1
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
MICAL-Like 1¹ ²		Molecule Interacting With Rab13² ³
MIRAB13¹ ² ³		MICAL-Like Protein 1²
MICAL-L1¹ ²		MIRab13³
KIAA1668¹ ³

External Ids:	HGNC: 29804¹	Entrez Gene: 85377²	Ensembl: ENSG00000100139⁷	UniProtKB: Q8N3F8³

Export aliases for MICALL1 gene to outside databases

Previous GC identifers: GC22P036632 GC22P021269

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MILK1_HUMAN, Q8N3F8

Function: May be a cytoskeletal regulator

Gene Wiki entry for MICALL1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000022.10 NC_018933.1 NT_011520.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MICALL1 gene promoter:
POU2F2 (Oct-2.1) Oct-B1 oct-B3 oct-B2 POU2F2 POU2F2C POU2F1 POU2F1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MICALL1 promoter sequence

Search SABiosciences Chromatin IP Primers for MICALL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MICALL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q13.1 HGNC cytogenetic band: 22q13.1

MICALL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MICALL1 gene location

GeneLoc information about chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P038301: view genomic region (about GC identifiers)

Start:	38,301,664 bp from pter	End:	38,338,829 bp from pter
Size:	37,166 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MILK1_HUMAN, Q8N3F8 (See protein sequence)

Recommended Name: MICAL-like protein 1

Size: 863 amino acids; 93441 Da

Subunit: Binds to Rab13

Subcellular location: Cytoplasm, cytoskeleton (By similarity)

Sequence caution: Sequence=CAD39036.1; Type=Frameshift; Positions=486, 507;

1 PDB 3D structure from and Proteopedia for MICALL1:

2KSP (3D)

Secondary accessions: Q5TI16 Q7RTP5 Q8N3N8 Q9BVL9 Q9BY92 Q9UH43 Q9UH44 Q9UH45

Explore the universe of human proteins at neXtProt for MICALL1: NX_Q8N3F8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N3F8

MICALL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_203744.1

ENSEMBL proteins:

ENSP00000404543 ENSP00000215957 ENSP00000406053 ENSP00000384608 ENSP00000416766

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
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	OriGene Purified Protein: MICALL1 Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for MICALL1
	GenScript Custom Purified and Recombinant Proteins Services for MICALL1
	Novus Biologicals MICALL1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MICALL1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--

MICALL1 for ontologies About GeneDecksing

MICALL1 Antibody Products:

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	GenScript Custom Superior Antibodies Services for MICALL1
	Novus Biologicals MICALL1 Antibodies
	Search for Antibodies for MICALL1 at Abcam
	Uscn Antibodies for MICALL1
	ThermoFisher Antibodies for MICALL1

Assay Products for MICALL1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MICALL1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for MICALL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MICALL1 for domains About GeneDecksing

3 InterPro domains/families:

IPR022735 DUF3585

IPR001715 CH-domain

IPR001781 Znf_LIM

Graphical View of Domain Structure for InterPro Entry Q8N3F8

ProtoNet protein and cluster: Q8N3F8

2 Blocks protein families:

IPB001715 Calponin-like actin-binding

IPB001781 Zn-binding protein

UniProtKB/Swiss-Prot: MILK1_HUMAN, Q8N3F8

Similarity: Contains 1 CH (calponin-homology) domain

Similarity: Contains 1 LIM zinc-binding domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MILK1_HUMAN, Q8N3F8

Function: May be a cytoskeletal regulator

miRNA Products:		OriGene 3'-UTR Clone: MICALL1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MICALL1
		8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate MICALL1 (see all 17):
		hsa-miR-520f hsa-miR-328 hsa-miR-125a-5p hsa-miR-3167 hsa-miR-374c hsa-miR-9 hsa-miR-3150b-3p hsa-miR-125b

		SwitchGear 3'UTR luciferase reporter plasmid: MICALL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MICALL1 (see all 4) OriGene shRNA RFP: MICALL1 OriGene siRNA: MICALL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MICALL1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MICALL1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MICALL1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MICALL1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MICALL1 (NM_033386)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MICALL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MICALL1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MICALL1
		Search LifeMap BioReagents cell lines for MICALL1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MICALL1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	19945174
GO:0008270	zinc ion binding	IEA	--

MICALL1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MICALL1

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/8 Interacting proteins for MICALL1 (Q8N3F8^{2, 3} ENSP00000215957⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946²^,³, ENSP00000300161⁴	MINT-50981 I2D: score=4 STRING: ENSP00000300161
YWHAG	P61981²^,³, ENSP00000306330⁴	MINT-50881 I2D: score=4 STRING: ENSP00000306330
PACSIN3	Q9UKS6³, ENSP00000298838⁴	I2D: score=1 STRING: ENSP00000298838
RAB1A	P62820³, ENSP00000387286⁴	I2D: score=1 STRING: ENSP00000387286
PACSIN1	Q9BY11³, ENSP00000244458⁴	I2D: score=1 STRING: ENSP00000244458

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MICALL1
Search CenterWatch for drugs/clinical trials and news about MICALL1 / MILK1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MICALL1 gene:

NM_033386.3

Unigene Cluster for MICALL1:

MICAL-like 1

Hs.517610 [show with all ESTs]

Unigene Representative Sequence: AB051455

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000445494 ENST00000215957(uc003aui.3) ENST00000489812 ENST00000454685

ENST00000402631 ENST00000424008

miRNA Products:		OriGene 3'-UTR Clone: MICALL1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MICALL1
		8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate MICALL1 (see all 17):
		hsa-miR-520f hsa-miR-328 hsa-miR-125a-5p hsa-miR-3167 hsa-miR-374c hsa-miR-9 hsa-miR-3150b-3p hsa-miR-125b

		SwitchGear 3'UTR luciferase reporter plasmid: MICALL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MICALL1 (see all 4) OriGene shRNA RFP: MICALL1 OriGene siRNA: MICALL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MICALL1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MICALL1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MICALL1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MICALL1 (NM_033386)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MICALL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MICALL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MICALL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat MICALL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MICALL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MICALL1

Additional cDNA sequence:

AB051455.1 AJ496196.1 AK056603.1 AK127819.1 AL833860.1 AL834373.1 BC001090.2 BC082243.1

CR456437.1 CR749566.1

9 DOTS entries:

DT.91987893 DT.445384 DT.40119502 DT.95275035 DT.100000098 DT.100791892 DT.120675737 DT.95275044

DT.121618611

24/180 AceView cDNA sequences (see all 180):

CD369120 AL833860 CB322062 CA307559 BU542642 BQ641566 BM977064 BG392350

BK000466 BU784516 BE906912 H55178 AW955290 CD369909 BU788189 AA938082

CA431485 M79089 CA306483 BG319575 AA299470 BC001090 BC082243 AK127819

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MICALL1 (see all 9) About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10a	·	10b	^	11	^	12	^	13a	·	13b	·	13c	^	14a	·	14b	^	15a	·	15b	^	16	^	17	^	18	^	19	^
SP1:
SP2:			-		-		-
SP3:							-
SP4:							-				-						-		-		-
SP5:

ExUns:	20
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for MICALL1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MICALL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTCATCACTG

About this image

MICALL1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

PureStem™ progenitor T42 (Embryonic Progenitor Cell)

PureStem™ progenitor U31 (Embryonic Progenitor Cell)

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MICALL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MICALL1

SOURCE GeneReport for Unigene cluster: Hs.517610

SABiosciences Custom PCR Arrays for MICALL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MICALL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat MICALL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MICALL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MICALL1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MICALL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MICALL1 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MICALL1¹	MICAL-like 1	69.34(n) 66.12(a)		418032 NM_001201448.1 NP_001188377.1
lizard (Anolis carolinensis)	Reptilia	MICALL1⁶	--	61(a)	1 ↔ 1	GL343460.1(59847-97079)
African clawed frog (Xenopus laevis)	Amphibia	Xl.30156²	Xenopus laevis transcribed sequence with weak similarity more	77.43(n)		48022287
zebrafish (Danio rerio)	Actinopterygii	micall1¹	MICAL-like 1	54.9(n) 52.19(a)		100149741 XM_001922140.2 XP_001922175.2
fruit fly (Drosophila melanogaster)	Insecta	MICAL-like¹	CG11259-PA	43.33(n) 32.84(a)		39475 NM_140364.2 NP_648621.1

ENSEMBL Gene Tree for MICALL1 (if available)
TreeFam Gene Tree for MICALL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MICALL1 gene

MICALL2² MICAL2² MICALCL² MICAL1² EHBP1² MICAL3² EHBP1L1²

6 SIMAP similar genes for MICALL1 using alignment to 4 protein entries: MILK1_HUMAN (see all proteins):

DKFZp686M2226 MICAL-L1 MICAL3 MICALCL EHBP1 MICALL2

MICALL1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144587532^1,2		--	38300304(+)	`GATCCA/GCCCAC`	1	--	us2k¹		0	--	--	--	--
rs191102378^1,2		--	38300447(+)	`GCCTCA/GGCCTC`	1	--	us2k¹		0	--	--	--	--
rs4346487^1,2	C,F,A,	--	38300474(+)	`acaggT/Catgag`	1	--	us2k¹		8		NA WA CSA EA	133
rs181840172^1,2		--	38300497(+)	`ACCCCC/GCCCCC`	1	--	us2k¹		0	--	--	--	--
rs201663466^1,2		--	38300497(+)	`ACCCC-/GCCCCC`	1	--	us2k¹		0	--	--	--	--
rs186359386^1,2		--	38300556(+)	`TGCTGA/GTGTCA`	1	--	us2k¹		0	--	--	--	--
rs148475423^1,2		--	38300563(+)	`GTCAGG/TATCCT`	1	--	us2k¹		0	--	--	--	--
rs12166310^1,2	H	--	38300642(+)	`GGACAG/CGGCAG`	1	--	us2k¹ tfbs³		4		NS EA	420
rs5750507^1,2	C,F,H,	--	38300785(+)	`AGCCCA/TGATTG`	1	--	us2k¹		9		NS EA NA	1048
rs61032413^1,2	C,F,	--	38300795(+)	`GGCAAG/ACTGGG`	1	--	us2k¹		4		WA CSA	123

HapMap Linkage Disequilibrium report for MICALL1 (38301664 - 38338829 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MICALL1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MICALL1

DNA2.0 Custom Variant and Variant Library Synthesis for MICALL1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MICALL1 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with MICALL1)

Utopia: connect your pdf to the dynamic
world of online information

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion. (PubMed id 12110185)^{1, 2, 3} Terman J.R.... Kolodkin A.L. (2002)
Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PubMed id 11258795)^{1, 2, 3} Hirosawa M....Ohara O. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{1, 2} Collins J.E.... Dunham I. (2004)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{1, 2} Dunham I....O'Brien K.P. (1999)
Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function. (PubMed id 22284051)¹ Zhang J....Caplan S. (2012)
MICAL-L1 is a tubular endosomal membrane hub that conn ects Rab35 and Arf6 with Rab8a. (PubMed id 21951725)¹ Rahajeng J....Caplan S. (2012)
MICAL-like1 mediates epidermal growth factor receptor endocytosis. (PubMed id 21795389)¹ Abou-Zeid N....Zahraoui A. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 85377	HGNC: 29804	AceView: MICAL-L1	Ensembl:ENSG00000100139	euGenes: HUgn85377
ECgene: MICALL1	H-InvDB: MICALL1

(According to HUGE)
About This Section

HUGE: KIAA1668

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MICALL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MICALL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MICALL1 gene:
Search GeneIP for patents involving MICALL1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MICALL1

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ThermoFisher Antibodies for MICALL1

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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes MICALL1 gene at Home site.

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MICALL1 Gene

MICAL-like 1

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MICALL1 Gene

MICAL-like 1

Aliasesfor MICALL1 gene

Summariesfor MICALL1 gene

Genomic Viewsfor MICALL1 gene

Proteinsfor MICALL1 gene

Protein Domains /Familiesfor MICALL1 gene

Functionfor MICALL1 gene

Pathways & Interactionsfor MICALL1 gene

Drugs & Compoundsfor MICALL1 gene

Transcriptsfor MICALL1 gene

Expression for MICALL1 gene

Orthologsfor MICALL1 gene

Paralogsfor MICALL1 gene

Genomic Variantsfor MICALL1 gene

Disorders / Diseasesfor MICALL1 gene

Publicationsfor MICALL1 gene

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Genome Databases showing MICALL1 gene

Other Databases showing MICALL1 gene

Specialized Databases showing MICALL1 gene

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for MICALL1 gene

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for MICALL1 gene

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for MICALL1 gene

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for MICALL1 gene

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for MICALL1 gene

Transcripts
for MICALL1 gene

Expression
for MICALL1 gene

Orthologs
for MICALL1 gene

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for MICALL1 gene

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for MICALL1 gene

Disorders / Diseases
for MICALL1 gene

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for MICALL1 gene

Intellectual Property
for MICALL1 gene

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for MICALL1 gene