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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MIA3 Gene

protein-coding GIFtS: 51
GCID: GC01P222791

melanoma inhibitory activity family, member 3

Explore 12 diseases affiliated with
MIA3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Melanoma Inhibitory Activity Family, Member 3¹ ²		D320² ³
TANGO¹ ² ³ ⁵		C219-Reactive Peptide² ³
KIAA0268¹ ³ ⁵		FLJ39207¹
TANGO1² ³ ⁵		ARNT²
UNQ6077¹ ²		C219 Reactive Peptide²
Transport And Golgi Organization Protein 1² ³		Melanoma Inhibitory Activity Protein 3²

External Ids:	HGNC: 24008¹	Entrez Gene: 375056²	Ensembl: ENSG00000154305⁷	OMIM: 613455⁵	UniProtKB: Q5JRA6³

Export aliases for MIA3 gene to outside databases

Previous GC identifers: GC01U901180 GC01P220858 GC01P193465

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MIA3_HUMAN, Q5JRA6

Function: Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in

cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding

SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific

to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete

COL7A1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_167186.1

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for MIA3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MIA3 promoter sequence

Search SABiosciences Chromatin IP Primers for MIA3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIA3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41 Ensembl cytogenetic band: 1q41 HGNC cytogenetic band: 1p36.33

MIA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MIA3 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P222791: view genomic region (about GC identifiers)

Start:	222,791,428 bp from pter	End:	222,841,354 bp from pter
Size:	49,927 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MIA3_HUMAN, Q5JRA6 (See protein sequence)

Recommended Name: Melanoma inhibitory activity protein 3 precursor

Size: 1907 amino acids; 213702 Da

Subunit: Interacts (via SH3 domain) with COL7A1. Associates with the COPII coat subunits Sec23/Sec24

Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Localizes at

endoplasmic reticulum exit sites. After loading of COL7A1 into transport carriers, it is not incorporated into COPII

carriers and remains in the endoplasmic reticulum membrane

Sequence caution: Sequence=BAC04810.1; Type=Erroneous initiation; Sequence=BAF83024.1; Type=Erroneous initiation;

Sequence=CAI40474.1; Type=Erroneous gene model prediction;

Secondary accessions: A8K2S0 A8MT05 A8MT13 B7Z430 Q14083 Q3S4X3 Q5JRA5 Q5JRB0 Q5JRB1 Q5JRB2 Q6UVY8

Q86Y60 Q8N8M5 Q92580

Alternative splicing: 4 isoforms: Q5JRA6-1 Q5JRA6-2 Q5JRA6-3 Q5JRA6-4

Explore the universe of human proteins at neXtProt for MIA3: NX_Q5JRA6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q5JRA6

MIA3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_940953.2

ENSEMBL proteins:

ENSP00000340900 ENSP00000341348 ENSP00000355062 ENSP00000345866 ENSP00000396598

ENSP00000340587

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MIA3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005789	endoplasmic reticulum membrane	IDA	19269366
GO:0016021	integral to membrane	IDA	19269366

MIA3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for MIA3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MIA3 for domains About GeneDecksing

2 InterPro domains/families:

IPR001452 SH3_domain

IPR011511 SH3_2

Graphical View of Domain Structure for InterPro Entry Q5JRA6

ProtoNet protein and cluster: Q5JRA6

UniProtKB/Swiss-Prot: MIA3_HUMAN, Q5JRA6

Domain: The proline-rich region (PRD) mediates the interaction with COPII coat subunits Sec23/24

Domain: Although 2 transmembrane domains are predicted, PubMed:19269366 showed that it only contains one transmembrane

domain. The other predicted transmembrane region is probably a hairpin-type region embedded into the membrane, which

does not cross the membrane. It is unclear which of the 2 predicted transmembrane regions is the transmembrane or the

hairpin-type region

Similarity: Belongs to the MIA/OTOR family. Tango1 subfamily

Similarity: Contains 1 SH3 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MIA3_HUMAN, Q5JRA6

Function: Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in

cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding

SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific

to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete

COL7A1

miRNA Products:		miRTarBase miRNAs that target MIA3: hsa-mir-107 (MIRT004537)

		OriGene 3'-UTR Clone: MIA3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MIA3
		8/54 QIAGEN miScript miRNA Assays for microRNAs that regulate MIA3 (see all 54):
		hsa-miR-21* hsa-miR-3164 hsa-miR-323-3p hsa-miR-607 hsa-miR-3146 hsa-miR-1245 hsa-miR-25 hsa-miR-30d

		SwitchGear 3'UTR luciferase reporter plasmid: MIA3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MIA3 (see all 4) OriGene shRNA RFP: MIA3 OriGene siRNA: MIA3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MIA3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MIA3

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIA3

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	17726152

MIA3 for ontologies About GeneDecksing

Animal Models:
10 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mia3):

cardiovascular system	cellular	craniofacial	growth/size	homeostasis/metabolism
integument	limbs/digits/tail	mortality/aging	respiratory system	skeleton

MIA3 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MIA3

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/8 Interacting proteins for MIA3 (Q5JRA6^{1, 2, 3} ENSP00000340900⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COL7A1	Q02388¹^,²^,³, ENSP00000332371⁴	EBI-2803073,EBI-724237 MINT-7217948 MINT-7217938 MINT-7217905 MINT-7217969 MINT-7217990 MINT-7217980 MINT-7217958 I2D: score=2 STRING: ENSP00000332371
SEC23A	Q15436²^,³, ENSP00000306881⁴	MINT-7217893 I2D: score=1 STRING: ENSP00000306881
SEC24C	P53992²^,³, ENSP00000321845⁴	MINT-7217922 I2D: score=1 STRING: ENSP00000321845
MINOS1	Q5TGZ0³, ENSP00000325562⁴	I2D: score=1 STRING: ENSP00000325562
CACNA1A	O00555³	I2D: score=1

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002687	positive regulation of leukocyte migration	IDA	17726152
GO:0006887	exocytosis	IMP	19269366
GO:0007162	negative regulation of cell adhesion	IDA	17726152
GO:0015031	protein transport	IMP	19269366
GO:0030336	negative regulation of cell migration	IDA	17044017

MIA3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MIA3
Search CenterWatch for drugs/clinical trials and news about MIA3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MIA3 gene:

NM_198551.2

Unigene Cluster for MIA3:

Melanoma inhibitory activity family, member 3

Hs.118474 [show with all ESTs]

Unigene Representative Sequence: NM_198551

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000344922(uc009xea.1 uc001hnl.3 uc001hnm.3) ENST00000470521

ENST00000344507 ENST00000354906 ENST00000340535 ENST00000495210 ENST00000467190

ENST00000476400 ENST00000475451 ENST00000479370 ENST00000450260 ENST00000477519

ENST00000344441

miRNA Products:		OriGene 3'-UTR Clone: MIA3 Browse OriGene MicroRNA Expression Plasmids
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		8/54 QIAGEN miScript miRNA Assays for microRNAs that regulate MIA3 (see all 54):
		hsa-miR-21* hsa-miR-3164 hsa-miR-323-3p hsa-miR-607 hsa-miR-3146 hsa-miR-1245 hsa-miR-25 hsa-miR-30d

		SwitchGear 3'UTR luciferase reporter plasmid: MIA3 3' UTR sequence

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		GenScript: all cDNA clones in your preferred vector: MIA3 (NM_198551)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MIA3
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIA3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIA3

Additional cDNA sequence:

AK025122.1 AK025506.1 AK026489.1 AK096526.1 AK290335.1 AK296712.1 AK307412.1 AY359091.1

BC031805.1 BC047116.1 D87742.1 DQ166034.1 L34688.1

22 DOTS entries:

DT.100030191 DT.100797779 DT.95238479 DT.40132318 DT.99942138 DT.121395400 DT.95165351 DT.100797778

DT.121395386 DT.118949 DT.91777140 DT.121395342 DT.121395352 DT.100797777 DT.95325611 DT.91777143

DT.91886157 DT.95165331 DT.95239479 DT.99941461 DT.102834231 DT.97797499

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MIA3 (see all 12) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	·	9c	·	9d	^	10	^	11	^	12	^	13	^	14	^	15a	·	15b	^	16	^	17a	·	17b	^	18	^	19a	·
SP1:
SP2:
SP3:
SP4:							-		-		-				-		-		-
SP5:

ExUns:	19b	^	20	^	21	^	22	^	23a	·	23b	^	24	^	25	^	26	^	27	^	28a	·	28b	^	29
SP1:																			-
SP2:																			-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for MIA3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MIA3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTTCCATT

About this image

MIA3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Cap Mesenchyme

Cap Mesenchyme Cells

Kidney

Kidney

S-shaped Body

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MIA3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MIA3

SOURCE GeneReport for Unigene cluster: Hs.118474

UniProtKB/Swiss-Prot: MIA3_HUMAN, Q5JRA6

Tissue specificity: Broadly expressed, except in bone marrow and peripheral blood mononuclear cells. Down-regulated in

melanoma tissue

SABiosciences Custom PCR Arrays for MIA3

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIA3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MIA3 gene from 4/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MIA3¹	melanoma inhibitory activity family, member 3	56.47(n) 44.6(a)		421337 XM_419399.3 XP_419399.3
lizard (Anolis carolinensis)	Reptilia	MIA3⁶	--	38(a)	1 ↔ 1	1(244435473-244469048)
zebrafish (Danio rerio)	Actinopterygii	mia3¹	melanoma inhibitory activity family, member 3	50.19(n) 41.45(a)		567041 XM_003200775.1 XP_003200823.1
fruit fly (Drosophila melanogaster)	Insecta	Tango1⁶	Transport and Golgi organization 1	12(a)	1 → many	2L(6649388-6654574)

ENSEMBL Gene Tree for MIA3 (if available)
TreeFam Gene Tree for MIA3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MIA3 gene

CTAGE4² CTAGE9² ENSG00000258941² CTAGE1² CTAGE5² CTAGE8²

3 SIMAP similar genes for MIA3 using alignment to 4 protein entries: MIA3_HUMAN (see all proteins):

OTOR MIA CTAGE5

MIA3 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for MIA3
PGOHUM00000251382

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs78171378^1,2	C,F,	--	222789458(+)	`AATGGT/CCTCAT`	1	--	us2k¹		1		EA	120
rs139477190^1,2		--	222789491(+)	`TTATCA/GTTGTA`	1	--	us2k¹		0	--	--	--	--
rs116045112^1,2	C,	--	222789714(+)	`AGAAAA/GAGATA`	1	--	us2k¹		1		NA	120
rs149664320^1,2		--	222789850(+)	`TTGTCC/TGTGAC`	1	--	us2k¹		0	--	--	--	--
rs145439363^1,2		--	222789868(+)	`AATGTA/GTATTT`	1	--	us2k¹		0	--	--	--	--
rs145724891^1,2	C,	--	222790001(+)	`CCACA-/TTCT TTCTT`	1	--	us2k¹		0	--	--	--	--
rs73122900^1,2	C,	--	222790020(+)	`TTTTAA/GGTAAT`	1	--	us2k¹		2		WA	120
rs67083268^1,2	C,	--	222790141(+)	`CAGGG-/CTGGAGAGCAT TGTAGCCACTCTTCTGGA`	1	--	us2k¹		0	--	--	--	--
rs67050541^1,2	C	--	222790143(+)	`CTTCT-/GGAGAGCATTG TAGCCACTCTTCTCTGGG`	1	--	us2k¹		1		NA	2
rs202225952^1,2		--	222790163(+)	`ACTCT-/TCTCTGG`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MIA3 (222791428 - 222841354 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MIA3
1 CNV: 97642
Human Gene Mutation Database (HGMD): MIA3

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIA3

DNA2.0 Custom Variant and Variant Library Synthesis for MIA3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MIA3 for disorders           About GeneDecksing

OMIM gene information: 613455    OMIM disorders: --

12 diseases for MIA3:    About MalaCards

melanoma coronary heart disease macular degeneration myocardial infarction

gigantism nephropathy pertussis hepatocellular carcinoma

meningioma atherosclerosis ataxia carcinoma

Human Genome Epidemiology (HuGE) Navigator: MIA3 (9 documents)

Export disorders for MIA3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MIA3 gene, integrated from 9 sources (see all 37):
(articles sorted by number of sources associating them with MIA3)

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Characterization and expression pattern of the novel MIA homolog TANGO. (PubMed id 15183315)^{1, 2, 3} Bosserhoff A.K.... Buettner R. (2004)
TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites. (PubMed id 19269366)^{1, 2} Saito K.... Malhotra V. (2009)
TANGO is a tumor suppressor of malignant melanoma. (PubMed id 17044017)^{1, 2} Arndt S. and Bosserhoff A.K. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{1, 2} Nagase T....Nomura N. (1996)
Analysis of a novel cDNA encoding a C219-reactive peptide isolated from methotrexate-selected multidrug-resistant human leukemic cells. (PubMed id 7758977)^{2, 9} Norris M.D.... Haber M. (1995)
Association study of MIA3 rs17465637 polymorphism with cardiovascular disease in rheumatoid arthritis patients. (PubMed id 22577832)¹ Garcia-Bermudez M....Gonzalez-Gay M.A. (2012)
MINOS1 is a conserved component of mitofilin complexe s and required for mitochondrial function and cristae organization. (PubMed id 22114354)¹ Alkhaja A.K....Deckers M. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 375056	HGNC: 24008	Ensembl:ENSG00000154305	euGenes: HUgn375056	ECgene: MIA3
H-InvDB: MIA3

(According to HUGE)
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HUGE: KIAA0268

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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Name	Description
PharmGKB entry for MIA3	Pharmacogenomics, SNPs, Pathways

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melanoma inhibitory activity family, member 3

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melanoma inhibitory activity family, member 3

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