Aliases for MIA3 Gene
External Ids for MIA3 Gene
Previous GeneCards Identifiers for MIA3 Gene
GeneCards Summary for MIA3 Gene
MIA3 (Melanoma Inhibitory Activity Family Member 3) is a Protein Coding gene. Diseases associated with MIA3 include inflammatory and toxic neuropathy and alcoholic neuropathy. Among its related pathways are Transport to the Golgi and subsequent modification and Vesicle-mediated transport. An important paralog of this gene is CTAGE9.
UniProtKB/Swiss-Prot for MIA3 Gene
Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.