Aliases for MIA2 Gene
- Melanoma Inhibitory Activity 2 2 3
- CTAGE Family Member 5, ER Export Factor 3 5
- CTAGE5 3 5
- Meningioma Expressed Antigen 6 (Coiled-Coil Proline-Rich) 3
- Cutaneous T-Cell Lymphoma-Associated Antigen 5 3
- Melanoma Inhibitory Activity Protein 2 3
- Meningioma-Expressed Antigen 6/11 3
- CTAGE Family, Member 5 3
External Ids for MIA2 Gene
Previous GeneCards Identifiers for MIA2 Gene
This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]
GeneCards Summary for MIA2 Gene
MIA2 (Melanoma Inhibitory Activity 2) is a Protein Coding gene. Diseases associated with MIA2 include Melanoma. Among its related pathways are Transport to the Golgi and subsequent modification and Vesicle-mediated transport. An important paralog of this gene is CTAGE1.
UniProtKB/Swiss-Prot for MIA2 Gene
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed:27138255). Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity).