Aliases for MGP Gene
External Ids for MGP Gene
The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
GeneCards Summary for MGP Gene
MGP (Matrix Gla Protein) is a Protein Coding gene. Diseases associated with MGP include acute apical periodontitis and keutel syndrome. Among its related pathways are Endochondral Ossification and PTM- gamma carboxylation, hypusine formation and arylsulfatase activation. GO annotations related to this gene include calcium ion binding and structural constituent of bone.
UniProtKB/Swiss-Prot for MGP Gene
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation