MFSD9 Gene
protein-coding GIFtS: 40
GCID: GC02M103332
|
|
major facilitator superfamily domain containing 9
| |
Aliases
for MFSD9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Major Facilitator Superfamily Domain Containing 91 2 | | MGC113321 | | Major Facilitator Superfamily Domain-Containing Protein 92 |
Export aliases for MFSD9 gene to outside databasesPrevious GC identifers: GC02M102700 GC02M097097 |
Summaries
for MFSD9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MFSD9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022171.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MFSD9 gene promoter:
SRF C/EBPbeta SRF (504 AA) LUN-1 STAT5A C/EBPalpha c-Ets-1 FOXO1a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MFSD9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MFSD9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q12.1 Ensembl cytogenetic band: 2q12.1 HGNC cytogenetic band: 2q12.1MFSD9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M103332: view genomic region
(about GC identifiers)
Start:
|
103,332,299 bp from pter |
End:
|
103,353,347 bp from pter |
Size:
|
21,049 bases |
Orientation:
|
minus strand |
|
Proteins
for MFSD9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MFSD9_HUMAN, Q8NBP5 (See
protein sequence)Recommended Name: Major facilitator superfamily domain-containing protein 9 Size: 474 amino acids; 50619 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q4ZG89 Q53TU0 Q96GQ4 Q9BRI8Explore the universe of human proteins at neXtProt for MFSD9: NX_Q8NBP5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NBP5
MFSD9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116107.3
ENSEMBL proteins: ENSP00000258436 ENSP00000408630 ENSP00000414870 ENSP00000392605 ENSP00000413641 ENSP00000402411
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
MFSD9 for ontologies About GeneDecksing
MFSD9 Antibody Products:
Assay Products for MFSD9: |
Protein
Domains /
Families
for MFSD9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MFSD9 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NBP5ProtoNet protein and cluster: Q8NBP5 UniProtKB/Swiss-Prot: MFSD9_HUMAN, Q8NBP5Similarity: Belongs to the major facilitator superfamily |
Function
for MFSD9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MFSD9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MFSD9 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MFSD9 (NM_032718) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MFSD9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD9 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD9 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005215 | transporter activity |
IEA | -- |
MFSD9 for ontologies About GeneDecksing
|
Pathways & Interactions
for MFSD9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MFSD9
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0055085 | transmembrane transport |
IEA | -- |
MFSD9 for ontologies About GeneDecksing
|
Drugs & Compounds
for MFSD9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MFSD9
Search CenterWatch for drugs/clinical trials and news about MFSD9
|
Transcripts
for MFSD9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MFSD9 gene: NM_032718.3 Unigene Cluster for MFSD9: Major facilitator superfamily domain containing 9 Hs.720914 [show with all ESTs]Unigene Representative Sequence: NM_0327188 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000496253 ENST00000258436 ENST00000438943(uc002tcb.2 uc010fja.2 uc021vls.1)
ENST00000437075 ENST00000411991 ENST00000428085 ENST00000421966 ENST00000462099
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MFSD9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MFSD9 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MFSD9 (NM_032718) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MFSD9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD9 |
Additional cDNA sequence: AK075376.1 AK290589.1 AK296768.1 AK307178.1 BC006242.2 BC009310.2 2 DOTS entries: DT.70103459 DT.92418044 24/114 AceView cDNA sequences (see all 114): BC006242 AA805395 AW020878 BG259808 AW513816 AI343521 BM792865 BC009310 BM311581 AI697733 R46013 U79290 AW001194 AI659212 CF890731 AW135925 BM310992 BM142327 BM845861 AI422195 CR599593 BG747312 AI280116 BP383312
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for MFSD9 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MFSD9
|
Expression
for MFSD9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MFSD9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTGCAGTTG
About this image
See MFSD9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MFSD9
SOURCE GeneReport for Unigene cluster: Hs.720914
SABiosciences Custom PCR Arrays for MFSD9
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MFSD9
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MFSD9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFSD9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFSD9 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD9 |
Orthologs
for MFSD9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MFSD9 gene from 3/15 species (see all 15) About this table
ENSEMBL Gene Tree for MFSD9 (if available)
TreeFam Gene Tree for MFSD9 (if available) |
Paralogs
for MFSD9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MFSD9 gene
- MFSD102 SLC22A182
2 SIMAP similar genes for MFSD9 using alignment to 5 protein entries: MFSD9_HUMAN (see all proteins):SLC46A1 MFSD10
MFSD9 for paralogs About GeneDecksing
|
Genomic Variants
for MFSD9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MFSD9 (103332299 - 103353347 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MFSD9: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MFSD9 |
|
Disorders
/ Diseases
for MFSD9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MFSD9 for disorders About GeneDecksing
1  disease for MFSD9: About MalaCardsmalaria
Export disorders for MFSD9 gene to outside databases
|
Publications
for MFSD9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MFSD9 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MFSD9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for MFSD9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MFSD9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MFSD9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MFSD9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MFSD9 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MFSD9 gene:
Search GeneIP for patents involving MFSD9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MFSD9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MFSD9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MFSD9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MFSD9 | | | OriGene Protein Over-expression Lysate for MFSD9 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MFSD9 | | OriGene 3'-UTR Clone for MFSD9 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MFSD9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MFSD9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MFSD9 | | OriGene Custom Protein Services for MFSD9 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MFSD9 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MFSD9 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MFSD9 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MFSD9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFSD9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFSD9 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MFSD9 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | MFSD9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD9 |
|  |  |  | | | | Search ThermoFisher Antibodies for MFSD9 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD9 |
|
|
|
|
