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Aliases for MFSD6L Gene

Aliases for MFSD6L Gene

  • Major Facilitator Superfamily Domain Containing 6-Like 2 3

External Ids for MFSD6L Gene

Previous GeneCards Identifiers for MFSD6L Gene

  • GC17M008642

Summaries for MFSD6L Gene

GeneCards Summary for MFSD6L Gene

MFSD6L (Major Facilitator Superfamily Domain Containing 6-Like) is a Protein Coding gene. An important paralog of this gene is MFSD6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MFSD6L Gene

Genomics for MFSD6L Gene

Regulatory Elements for MFSD6L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MFSD6L Gene

8,797,110 bp from pter
8,799,349 bp from pter
2,240 bases
Minus strand

Genomic View for MFSD6L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MFSD6L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MFSD6L Gene

Proteins for MFSD6L Gene

  • Protein details for MFSD6L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Major facilitator superfamily domain-containing protein 6-like
    Protein Accession:
    Secondary Accessions:
    • Q6YL34
    • Q8NA76

    Protein attributes for MFSD6L Gene

    586 amino acids
    Molecular mass:
    64005 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAM98769.1; Type=Frameshift; Positions=365; Evidence={ECO:0000305};

neXtProt entry for MFSD6L Gene

Proteomics data for MFSD6L Gene at MOPED

Post-translational modifications for MFSD6L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MFSD6L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MFSD6L Gene

Domains for MFSD6L Gene

Protein Domains for MFSD6L Gene


Suggested Antigen Peptide Sequences for MFSD6L Gene

Graphical View of Domain Structure for InterPro Entry



  • Q8IWD5
  • Belongs to the major facilitator superfamily. MFSD6 family.
genes like me logo Genes that share domains with MFSD6L: view

No data available for Gene Families for MFSD6L Gene

Function for MFSD6L Gene

Animal Model Products

CRISPR Products

miRNA for MFSD6L Gene

miRTarBase miRNAs that target MFSD6L

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MFSD6L Gene

Localization for MFSD6L Gene

Subcellular locations from UniProtKB/Swiss-Prot for MFSD6L Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for MFSD6L Gene COMPARTMENTS Subcellular localization image for MFSD6L gene
Compartment Confidence
plasma membrane 3
cytoskeleton 1
cytosol 1

Gene Ontology (GO) - Cellular Components for MFSD6L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MFSD6L: view

Pathways for MFSD6L Gene

SuperPathways for MFSD6L Gene

No Data Available

Interacting Proteins for MFSD6L Gene

Gene Ontology (GO) - Biological Process for MFSD6L Gene


No data available for Pathways by source for MFSD6L Gene

Transcripts for MFSD6L Gene

mRNA/cDNA for MFSD6L Gene

(3) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MFSD6L Gene

Major facilitator superfamily domain containing 6-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MFSD6L

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for MFSD6L

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MFSD6L Gene

No ASD Table

Relevant External Links for MFSD6L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MFSD6L Gene

mRNA expression in normal human tissues for MFSD6L Gene

mRNA differential expression in normal tissues according to GTEx for MFSD6L Gene

This gene is overexpressed in Testis (22.2), Pancreas (5.6), and Pituitary (4.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MFSD6L Gene

SOURCE GeneReport for Unigene cluster for MFSD6L Gene Hs.213603

genes like me logo Genes that share expressions with MFSD6L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MFSD6L Gene

Orthologs for MFSD6L Gene

This gene was present in the common ancestor of animals.

Orthologs for MFSD6L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MFSD6L 35
  • 98.98 (n)
  • 97.95 (a)
  • 97 (a)
(Bos Taurus)
Mammalia MFSD6L 35
  • 79.41 (n)
  • 69.97 (a)
  • 65 (a)
(Canis familiaris)
Mammalia MFSD6L 35
  • 78.67 (n)
  • 74.3 (a)
  • 73 (a)
(Mus musculus)
Mammalia Mfsd6l 35
  • 77.34 (n)
  • 68.5 (a)
Mfsd6l 16
Mfsd6l 36
  • 67 (a)
(Monodelphis domestica)
Mammalia MFSD6L 36
  • 53 (a)
(Rattus norvegicus)
Mammalia Mfsd6l 35
  • 77.44 (n)
  • 66.5 (a)
(Anolis carolinensis)
Reptilia MFSD6L 36
  • 44 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia mfsd6l 35
  • 53.22 (n)
  • 44.44 (a)
(Danio rerio)
Actinopterygii mfsd6l 35
  • 49.86 (n)
  • 41.34 (a)
mfsd6l 36
  • 33 (a)
fruit fly
(Drosophila melanogaster)
Insecta Sug 36
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 31 (a)
Species with no ortholog for MFSD6L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MFSD6L Gene

Gene Tree for MFSD6L (if available)
Gene Tree for MFSD6L (if available)

Paralogs for MFSD6L Gene

Paralogs for MFSD6L Gene

genes like me logo Genes that share paralogs with MFSD6L: view

Variants for MFSD6L Gene

Sequence variations from dbSNP and Humsavar for MFSD6L Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs197078 -- 8,799,485(-) GCTCA(A/G)AACGC upstream-variant-2KB
rs367945 -- 8,799,344(-) cGCCT(C/T)TCCCT utr-variant-5-prime
rs904168 -- 8,799,810(-) cttgg(A/T)cagtg upstream-variant-2KB
rs1826924 -- 8,800,296(-) AGGTG(A/G)CTTGG upstream-variant-2KB
rs1826925 -- 8,800,102(-) TGTAG(A/G)TTAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MFSD6L Gene

Variant ID Type Subtype PubMed ID
nsv518675 CNV Gain 19592680
nsv907668 CNV Loss 21882294
nsv1969 CNV Loss 18451855

Relevant External Links for MFSD6L Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MFSD6L Gene

Disorders for MFSD6L Gene

Relevant External Links for MFSD6L

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with MFSD6L: view

No data available for UniProtKB/Swiss-Prot for MFSD6L Gene

Publications for MFSD6L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MFSD6L Gene

Sources for MFSD6L Gene

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