Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



MFSD6 Gene

protein-coding   GIFtS: 48
GCID: GC02P191273

Major Facilitator Superfamily Domain Containing 6

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Major Facilitator Superfamily Domain Containing 61 2
MMR22 3 5
Macrophage MHC Class I Receptor 2 Homolog2 3
hMMR22
Macrophage MHC Receptor 22
Major Facilitator Superfamily Domain-Containing Protein 62

External Ids:    HGNC: 247111   Entrez Gene: 548422   Ensembl: ENSG000001516907   OMIM: 6134765   UniProtKB: Q6ZSS73   

Export aliases for MFSD6 gene to outside databases

Previous GC identifers: GC02P190981 GC02P183132


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for MFSD6 Gene:
MFSD6 (major facilitator superfamily domain containing 6) is a protein-coding gene. Diseases associated with MFSD6 include loeys-dietz syndrome, and ehlers-danlos syndrome. An important paralog of this gene is MFSD6L.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MFSD6 gene promoter:
         MyoD   AP-4   E47   HEN1   SRY   FOXJ2 (long isoform)   FOXJ2   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MFSD6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MFSD6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q32.2   Ensembl cytogenetic band:  2q32.2   HGNC cytogenetic band: 2q32.2

MFSD6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MFSD6 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P191273:  view genomic region     (about GC identifiers)

Start:
191,273,081 bp from pter      End:
191,373,931 bp from pter
Size:
100,851 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: MFSD6_HUMAN, Q6ZSS7 (See protein sequence)
Recommended Name: Major facilitator superfamily domain-containing protein 6  
Size: 791 amino acids; 88088 Da
Subunit: May interact with HLA-B62
Sequence caution: Sequence=AAY24173.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA90987.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=EAX10868.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: D3KSZ4 Q86TH2 Q9NXM3

Explore the universe of human proteins at neXtProt for MFSD6: NX_Q6ZSS7

Explore proteomics data for MFSD6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MFSD6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060164.3  
    ENSEMBL proteins: 
     ENSP00000398737   ENSP00000400131   ENSP00000376141   ENSP00000403762   ENSP00000397276  
     ENSP00000406837   ENSP00000404511   ENSP00000281416   ENSP00000440917  

    MFSD6 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for MFSD6
    OriGene Protein Over-expression Lysate for MFSD6
    OriGene Custom MassSpec
    OriGene Custom Protein Services for MFSD6
    GenScript Custom Purified and Recombinant Proteins Services for MFSD6
    Novus Biologicals MFSD6 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MFSD6

    MFSD6 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for MFSD6
    OriGene Custom Antibody Services for MFSD6
    Novus Biologicals MFSD6 Antibodies
    Abcam antibodies for MFSD6
    Cloud-Clone Corp. Antibodies for MFSD6
    ThermoFisher Antibodies for MFSD6
    LSBio Antibodies in human, mouse, rat for MFSD6

    MFSD6 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MFSD6
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MFSD6
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MFSD6
    Cloud-Clone Corp. CLIAs for MFSD6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR024989 MFS_assoc_dom
     IPR011701 MFS
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q6ZSS7

    ProtoNet protein and cluster: Q6ZSS7

    UniProtKB/Swiss-Prot: MFSD6_HUMAN, Q6ZSS7
    Similarity: Belongs to the major facilitator superfamily. MFSD6 family


    MFSD6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 GenomeRNAi human phenotype for MFSD6:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MFSD6
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MFSD6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MFSD6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MFSD6

    miRNA
    Products:
        
    miRTarBase miRNAs that target MFSD6:
    hsa-mir-101-3p (MIRT027391), hsa-mir-335-5p (MIRT019038), hsa-mir-130b-5p (MIRT038299)

    Block miRNA regulation of human, mouse, rat MFSD6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MFSD6 (see all 58):
    hsa-miR-607 hsa-miR-3607-3p hsa-miR-139-5p hsa-miR-30d hsa-miR-301a hsa-miR-138-2* hsa-miR-519a hsa-miR-548m
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MFSD6
    Predesigned siRNA for gene silencing in human, mouse, rat MFSD6

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MFSD6

    Clone
    Products:
         
    OriGene clones in human, mouse for MFSD6 (see all 6)
    OriGene ORF clones in mouse, rat for MFSD6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MFSD6 (NM_017694)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFSD6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD6

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MFSD6
    Browse ESI BIO Cell Lines and PureStem Progenitors for MFSD6 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    MFSD6_HUMAN, Q6ZSS7: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytoskeleton1
    cytosol1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    MFSD6 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MFSD6
    Interactions:

        Search GeneGlobe Interaction Network for MFSD6

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0055085transmembrane transport IEA--

    MFSD6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MFSD6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for MFSD6 gene: 
    NM_017694.3  

    Unigene Cluster for MFSD6:

    Major facilitator superfamily domain containing 6
    Hs.418581  [show with all ESTs]
    Unigene Representative Sequence: NM_017694
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417958 ENST00000432036 ENST00000392328(uc002urz.2) ENST00000445546
    ENST00000434582 ENST00000489793 ENST00000444317 ENST00000486123 ENST00000412482
    ENST00000281416(uc010zge.1) ENST00000535751
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MFSD6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MFSD6 (see all 58):
    hsa-miR-607 hsa-miR-3607-3p hsa-miR-139-5p hsa-miR-30d hsa-miR-301a hsa-miR-138-2* hsa-miR-519a hsa-miR-548m
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MFSD6
    Predesigned siRNA for gene silencing in human, mouse, rat MFSD6
    Clone
    Products:
         
    OriGene clones in human, mouse for MFSD6 (see all 6)
    OriGene ORF clones in mouse, rat for MFSD6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MFSD6 (NM_017694)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFSD6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD6
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MFSD6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MFSD6
      QuantiTect SYBR Green Assays in human, mouse, rat MFSD6
      QuantiFast Probe-based Assays in human, mouse, rat MFSD6

    Additional mRNA sequence: AK127176.1 

    3 DOTS entries:

    DT.443107  DT.121021039  DT.95323745 

    Selected AceView cDNA sequences (see all 158):

    BM782857 AA259115 AW002378 BX505356 AW473896 AK000167 BP334524 AA932492 
    AA348014 BM819285 AA736690 BC039058 AA133178 BC050537 AA436105 BU731494 
    AI096536 BM842555 BI489781 AA846303 AI362676 BM969012 AK127176 BM761320 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    MFSD6 expression in normal human tissues (normalized intensities)      MFSD6 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGAAATAAA
    MFSD6 Expression
    About this image


    MFSD6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Heart (Cardiovascular System)
             Outflow Tract
     
     Bone (Muscoskeletal System)
             Zeugopod Growth Plate
     
     Intestine (Gastrointestinal Tract)
     
     Colon (Gastrointestinal Tract)
    MFSD6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MFSD6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.418581

    UniProtKB/Swiss-Prot: MFSD6_HUMAN, Q6ZSS7
    Tissue specificity: Widely expressed. Expression levels in peripheral blood mononuclear cells are highly variable
    between individuals, including no expression at all

        Custom PCR Arrays for MFSD6
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for MFSD6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MFSD6
    QuantiTect SYBR Green Assays in human, mouse, rat MFSD6
    QuantiFast Probe-based Assays in human, mouse, rat MFSD6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for MFSD6 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mfsd61 , 5 major facilitator superfamily domain containing 61, 5 86.5(n)1
    87.97(a)1
      1 (26.99 cM)5
    986821  NM_133829.21  NP_598590.21 
     526562865 
    chicken
    (Gallus gallus)
    Aves MFSD61 major facilitator superfamily domain containing 6 73.87(n)
    80.64(a)
      423978  XM_421837.3  XP_421837.1 
    lizard
    (Anolis carolinensis)
    Reptilia MFSD66
    major facilitator superfamily domain containing 6
    76(a)
    1 ↔ 1
    2(134648332-134699125)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mfsd61 major facilitator superfamily domain containing 6 66.81(n)
    70.72(a)
      100170426  XM_002941594.2  XP_002941640.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CF348520.12   -- 76.28(n)    CF348520.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG128581 CG12858 51.18(n)
    41.77(a)
      36634  NM_001259394.1  NP_001246323.1 
    worm
    (Caenorhabditis elegans)
    Secernentea R13A5.91 R13A5.9 45.08(n)
    35.42(a)
      176073  NM_066261.4  NP_498662.1 


    ENSEMBL Gene Tree for MFSD6 (if available)
    TreeFam Gene Tree for MFSD6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for MFSD6 gene
    MFSD6L2  

    MFSD6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for MFSD6 (see all 1665)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1473560561,2
    --183130546(+) TTTGGA/GAGGCT 1 -- us2k10--------
    rs38410881,2
    C--190686373(+) ATAAA-/CAGTGTT 1 -- int1 tfbs31Minor allele frequency- CA:0.00NA 2
    rs1394214701,2
    C--191271210(+) AGCTAC/TTCAGG 1 -- us2k10--------
    rs621809891,2
    C--191271244(+) GAACCT/CGGGAG 1 -- us2k12Minor allele frequency- C:0.25NA 4
    rs1450489351,2
    --191271266(+) AGTGAC/GCTGAG 1 -- us2k10--------
    rs1121168211,2
    C--191271288(+) GCAATC/ACGGCC 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1421642671,2
    --191271514(+) GTGAGA/GGAATT 1 -- us2k10--------
    rs1131571031,2
    C--191271570(+) CCCAAA/GGAAAA 1 -- us2k10--------
    rs562787381,2
    C,F--191271709(+) GAAGAG/CAAGGG 1 -- us2k14Minor allele frequency- C:0.20WA CSA NA 242
    rs1830452121,2
    --191271805(+) CAATAC/TTGAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MFSD6 (191273081 - 191373931 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MFSD6:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2318138CNV Deletion18987734
    esv2721268CNV Deletion23290073
    esv1062211CNV Insertion17803354
    esv33134CNV Gain17666407

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MFSD6
    DNA2.0 Custom Variant and Variant Library Synthesis for MFSD6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613476    OMIM disorders: --

    4 diseases for MFSD6:    About MalaCards
    loeys-dietz syndrome    ehlers-danlos syndrome    malaria    neuronitis

    1 disease from the University of Copenhagen DISEASES database for MFSD6:
    Loeys-Dietz syndrome

    MFSD6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MFSD6
    Human Genome Epidemiology (HuGE) Navigator: MFSD6 (3 documents)

    Export disorders for MFSD6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for MFSD6 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with MFSD6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. HLA-B62 as a possible ligand for the human homologue of mouse macrophage MHC receptor 2 (MMR2) on monocytes. (PubMed id 20123006)1, 2 Shimizu T.... Yoshida R. (Gene 2010)
    3. High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. (PubMed id 19401682)1, 4 Maestrini E....Monaco A.P. (Mol. Psychiatry 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    6. Gene-environment interaction in the etiology of mathematical ability using SNP sets. (PubMed id 20978832)1 Docherty S.J....Plomin R. (Behav. Genet. 2011)
    7. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 54842 HGNC: 24711 AceView: FLJ20160 Ensembl:ENSG00000151690 euGenes: HUgn54842
    ECgene: MFSD6 H-InvDB: MFSD6

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for MFSD6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for MFSD6 gene:
    Search GeneIP for patents involving MFSD6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for MFSD6   OriGene RNAi products in human, mouse, rat for MFSD6  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for MFSD6  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for MFSD6  
     OriGene qSTAR qPCR primer pairs in human, mouse for MFSD6   OriGene Purified Protein for MFSD6  
     OriGene ORF clones in mouse, rat for MFSD6   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MFSD6   OriGene Custom Protein Services for MFSD6  

     
     
     Block miRNA regulation of human, mouse, rat MFSD6 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MFSD6
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MFSD6 Predesigned siRNA for gene silencing in human, mouse, rat MFSD6
     QuantiFast Probe-based Assays in human, mouse, rat MFSD6 QuantiTect SYBR Green Assays in human, mouse, rat MFSD6
     Custom PCR Arrays for MFSD6 Search Chromatin IP Primers for MFSD6
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MFSD6  Search GeneGlobe Interaction Network for MFSD6
     Regulatory tfbs in MFSD6 promoter
     GenScript Custom Purified and Recombinant Proteins Services for MFSD6 GenScript cDNA clones with any tag delivered in your preferred vector for MFSD6
     GenScript Custom Assay Services for MFSD6 GenScript Custom overexpressing Cell Line Services for MFSD6
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for MFSD6
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     MFSD6 antibodies
     MFSD6 proteins
     Antibodies for MFSD6
     See all of Abcam's Antibodies, Kits and Proteins for MFSD6
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for MFSD6
     Antibodies for MFSD6
     ELISAs for MFSD6
     CLIAs for MFSD6



     Browse ESI BIO Cell Lines and PureStem Progenitors for MFSD6
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD6
     Browse SwitchGear 3'UTR luciferase reporter plasmids for MFSD6
     Browse SwitchGear Promoter luciferase reporter plasmids for MFSD6
     ThermoFisher Antibodies for MFSD6
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD6
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MFSD6
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MFSD6
     LSBio Antibodies in human, mouse, rat for MFSD6
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MFSD6 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4