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MFSD2A Gene

protein-coding   GIFtS: 46
GCID: GC01P040421

Major Facilitator Superfamily Domain Containing 2A

(Previous name: major facilitator superfamily domain containing 2)
(Previous symbol: MFSD2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Major Facilitator Superfamily Domain Containing 2A1 2
MFSD21 2 3
Major Facilitator Superfamily Domain Containing 21
Major Facilitator Superfamily Domain-Containing Protein 2A2

External Ids:    HGNC: 258971   Entrez Gene: 848792   Ensembl: ENSG000001683897   OMIM: 6143975   UniProtKB: Q8NA293   

Export aliases for MFSD2A gene to outside databases

Previous GC identifers: GC01P040194 GC01P038539


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MFSD2A Gene:
MFSD2A (major facilitator superfamily domain containing 2A) is a protein-coding gene. Diseases associated with MFSD2A include hepatoblastoma, and choriocarcinoma. An important paralog of this gene is MFSD2B.

UniProtKB/Swiss-Prot: MFS2A_HUMAN, Q8NA29
Function: Plays a role in thermogenesis via beta-adrenergic signaling pathway. May be the main plasma membrane
tunicamycin transporter

Gene Wiki entry for MFSD2A (MFSD2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for MFSD2A
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMFSD2A promoter sequence
   Search Chromatin IP Primers for MFSD2A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MFSD2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.2   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34.2

MFSD2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MFSD2A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P040421:  view genomic region     (about GC identifiers)

Start:
40,420,784 bp from pter      End:
40,435,638 bp from pter
Size:
14,855 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MFS2A_HUMAN, Q8NA29 (See protein sequence)
Recommended Name: Major facilitator superfamily domain-containing protein 2A  
Size: 543 amino acids; 60170 Da
Secondary accessions: A8K675 Q6UWU5 Q96F59 Q9BRC8
Alternative splicing: 3 isoforms:  Q8NA29-1   Q8NA29-2   Q8NA29-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MFSD2A: NX_Q8NA29

Explore proteomics data for MFSD2A at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn230, Asn240

  • See MFSD2A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001129965.1  NP_001274737.1  NP_001274738.1  NP_116182.2  

    ENSEMBL proteins: 
     ENSP00000361898   ENSP00000407606   ENSP00000361895   ENSP00000391261  

    MFSD2A Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MFSD2A

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    LSBio Antibodies in human, mouse, rat for MFSD2A

    MFSD2A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for MFSD2A
    Cloud-Clone Corp. CLIAs for MFSD2A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q8NA29

    ProtoNet protein and cluster: Q8NA29

    UniProtKB/Swiss-Prot: MFS2A_HUMAN, Q8NA29
    Similarity: Belongs to the major facilitator superfamily


    MFSD2A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MFS2A_HUMAN, Q8NA29
    Function: Plays a role in thermogenesis via beta-adrenergic signaling pathway. May be the main plasma membrane
    tunicamycin transporter

    Phenotypes:
         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mfsd2a):

     adipose tissue  behavior/neurological  cellular  growth/size/body  homeostasis/metabolism 
     liver/biliary system  mortality/aging 

    MFSD2A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Mfsd2atm1Dls for MFSD2A

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MFSD2A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MFSD2A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MFSD2A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MFSD2A

    miRNA
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    Block miRNA regulation of human, mouse, rat MFSD2A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MFSD2A (see all 10):
    hsa-miR-513a-5p hsa-miR-27a hsa-miR-4255 hsa-miR-128 hsa-miR-3681* hsa-miR-3647-3p hsa-miR-633 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidMFSD2A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MFSD2A
    Predesigned siRNA for gene silencing in human, mouse, rat MFSD2A

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for MFSD2A

    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): MFSD2A (NM_032793)
    Sino Biological Human cDNA Clone for MFSD2A
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFSD2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD2A

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for MFSD2A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD2A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MFS2A_HUMAN, Q8NA29: Cell membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum membrane (By
    similarity); Multi-pass membrane protein (Potential). Note=Cytoplasmic punctae that may represent vesicles
    shuttling between the endoplasmic reticulum and the plasma membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum2
    cytosol1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005886plasma membrane IDA--
    GO:0016021integral component of membrane IEA--

    MFSD2A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MFSD2A
    Interactions:

        Search GeneGlobe Interaction Network for MFSD2A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for MFSD2A (ENSP000003618954) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZMYM1ENSP000003529204STRING: ENSP00000352920
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0055085transmembrane transport ----

    MFSD2A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MFSD2A (MFS2A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MFSD2A gene (4 alternative transcripts): 
    NM_001136493.2  NM_001287808.1  NM_001287809.1  NM_032793.4  

    Unigene Cluster for MFSD2A:

    Major facilitator superfamily domain containing 2A
    Hs.655177  [show with all ESTs]
    Unigene Representative Sequence: AF370364
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372811(uc010ojb.1 uc001ceu.3 uc010ojc.2 uc009vvy.3)
    ENST00000434861 ENST00000372809(uc001cev.3) ENST00000483824 ENST00000469745
    ENST00000480630 ENST00000491515 ENST00000459917 ENST00000481612 ENST00000420632

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MFSD2A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MFSD2A (see all 10):
    hsa-miR-513a-5p hsa-miR-27a hsa-miR-4255 hsa-miR-128 hsa-miR-3681* hsa-miR-3647-3p hsa-miR-633 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidMFSD2A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MFSD2A
    Predesigned siRNA for gene silencing in human, mouse, rat MFSD2A
    Clone
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    OriGene ORF clones in mouse, rat for MFSD2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MFSD2A (NM_032793)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFSD2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFSD2A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MFSD2A
    OriGene qSTAR qPCR primer pairs in human, mouse for MFSD2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MFSD2A
      QuantiTect SYBR Green Assays in human, mouse, rat MFSD2A
      QuantiFast Probe-based Assays in human, mouse, rat MFSD2A

    Additional mRNA sequence: 

    AB073383.1 AF289609.1 AF370364.1 AF370393.1 AK074186.1 AK075183.1 AK093223.1 AK291540.1 
    AK297991.1 AL834184.1 AY358636.1 BC006353.2 BC011587.1 BC069694.1 BC069771.1 BC092414.1 

    23 DOTS entries:

    DT.100025632  DT.455069  DT.100025634  DT.97823445  DT.121393426  DT.91871632  DT.121393337  DT.95265519 
    DT.121393425  DT.97816338  DT.101986336  DT.91965396  DT.121393349  DT.121393352  DT.91746908  DT.95193735 
    DT.121393328  DT.121393401  DT.121393415  DT.114349  DT.121393421  DT.95109872  DT.95193737 

    Selected AceView cDNA sequences (see all 232):

    BM746770 BM827369 BG485328 AK093223 AL042399 CR611403 AL514028 CB152391 
    BM763764 BP353143 AB073383 CR621139 BI916322 AL834184 BC006353 AL543601 
    BC011587 BC069771 CR608085 AK027396 AL548198 BM764676 AK075183 AA367854 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MFSD2A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAAGGCCA
    MFSD2A Expression
    About this image


    MFSD2A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Adult Endothelial Cells Blood Brain Barrier
             Oligodendrocyte-like cells
     
     Endothelium (Cardiovascular System)    fully expand to see all 3 entries
             Adult Endothelial Cells Blood Brain Barrier
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Interscapular Brown Adipose Depot
             HyStem+BMP4-induced 7SMOO32 cells
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Spinal Cord (Nervous System)
             Oligodendrocyte-like cells
    MFSD2A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MFSD2A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655177
        Custom PCR Arrays for MFSD2A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFSD2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MFSD2A gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mfsd2a1 , 5 major facilitator superfamily domain containing 2A1, 5 84.25(n)1
    85.26(a)1
      4 (57.34 cM)5
    765741  NM_029662.21  NP_083938.21 
     1229468505 
    chicken
    (Gallus gallus)
    Aves MFSD2A1 major facilitator superfamily domain containing 2A 74.9(n)
    76.48(a)
      419679  XM_417826.4  XP_417826.3 
    lizard
    (Anolis carolinensis)
    Reptilia MFSD2A6
    major facilitator superfamily domain containing 2A...
    73(a)
    1 ↔ 1
    GL343498.1(241021-281658)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mfsd2a1 major facilitator superfamily domain containing 2A 67.32(n)
    71.23(a)
      780091  NM_001079167.1  NP_001072635.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mfsd2ab1 major facilitator superfamily domain containing 2ab 65.12(n)
    66.09(a)
      445176  NM_001003570.1  NP_001003570.1 


    ENSEMBL Gene Tree for MFSD2A (if available)
    TreeFam Gene Tree for MFSD2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MFSD2A gene
    MFSD2B2  
    1 SIMAP similar gene for MFSD2A using alignment to 3 protein entries:     MFS2A_HUMAN (see all proteins):
    MFSD2B

    MFSD2A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MFSD2A (see all 389)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1122918571,2
    C--40418790(+) ATTAA-/T/TT  
            
    TTTTT
    2 -- us2k11CSA 2
    rs40685441,2
    C--40418805(+) ttttt-/TT/TTT
            
    gagac
    4 -- us2k1 cds10--------
    rs1492321411,2
    --40418852(+) GGCACA/GATCTC 2 -- us2k10--------
    rs1876096871,2
    --40419007(+) TGGTCA/CGGAAC 2 -- us2k10--------
    rs46601551,2
    C,F,A--40419022(+) GACTTC/TGTGAT 2 -- us2k14Minor allele frequency- T:0.21NA WA 242
    rs1917164481,2
    --40419023(+) ACTTCA/GTGATC 2 -- us2k10--------
    rs1444459361,2
    --40419150(+) CAGCCA/GCACAG 2 -- us2k10--------
    rs1842210691,2
    --40419298(+) AAGATA/GCGGTT 2 -- us2k10--------
    rs1379031501,2
    --40419301(+) ATGCGA/GTTCCT 2 -- us2k10--------
    rs1881680491,2
    --40419326(+) TTGTCA/CACCGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for MFSD2A (40420784 - 40435638 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MFSD2A:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv49e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): MFSD2A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MFSD2A
    DNA2.0 Custom Variant and Variant Library Synthesis for MFSD2A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614397    OMIM disorders: --

    4 diseases for MFSD2A:    
    About MalaCards
    hepatoblastoma    choriocarcinoma    lung cancer    endotheliitis


    MFSD2A for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: MFSD2A (0 documents)

    Export disorders for MFSD2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MFSD2A gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with MFSD2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mfsd2a encodes a novel major facilitator superfamily domain- containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis. (PubMed id 18694395)1, 2, 3 Angers M.... Jetten A.M. (Biochem. J. 2008)
    2. A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin. (PubMed id 21677192)1, 2 Reiling J.H.... Sabatini D.M. (Proc. Natl. Acad. Sci. U.S.A. 2011)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    5. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (Oncogene 2004)
    6. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    10. MFSD2a, the Syncytin-2 receptor, is important for trophoblast fusion. (PubMed id 23177091)1 Toufaily C....Barbeau B. (Placenta 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84879 HGNC: 25897 AceView: FLJ14490 Ensembl:ENSG00000168389 euGenes: HUgn84879
    ECgene: MFSD2A H-InvDB: MFSD2A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MFSD2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MFSD2A gene:
    Search GeneIP for patents involving MFSD2A

    GeneCards and IP:
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