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Aliases for MFSD14C Gene

Aliases for MFSD14C Gene

  • Major Facilitator Superfamily Domain Containing 14C 2 3 5
  • Hippocampus Abundant Transcript-Like 2 2 3
  • HIATL2 3 4
  • Major Facilitator Superfamily Domain-Containing 14C 4
  • Hippocampus Abundant Gene Transcript-Like 2 3

External Ids for MFSD14C Gene

Previous HGNC Symbols for MFSD14C Gene

  • HIATL2

Summaries for MFSD14C Gene

GeneCards Summary for MFSD14C Gene

MFSD14C (Major Facilitator Superfamily Domain Containing 14C) is a Pseudogene. An important paralog of this gene is MFSD14B.

Additional gene information for MFSD14C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MFSD14C Gene

Genomics for MFSD14C Gene

Regulatory Elements for MFSD14C Gene

Enhancers for MFSD14C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H097918 1.8 FANTOM5 ENCODE dbSUPER 44 -907.5 -907530 5.9 ZFP64 FEZF1 DMAP1 YY1 ZNF416 ZNF143 SP3 NFYC MEF2D ZNF610 NCBP1 TSTD2 MFSD14C TRMO ZNF322P1 ENSG00000235494 NUTM2G ZNF782 LOC286359 TCEA1P1
GH09H097631 1.4 ENCODE dbSUPER 32.5 -619.7 -619706 4 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF766 NCBP1 MFSD14C LOC441454 ZNF782 NUTM2G TSTD2 ZNF322P1 ENSG00000224848 ZNF510 ENSG00000254633
GH09H097236 1.1 ENCODE 23.4 -224.7 -224690 2.9 HDGF ARNT ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF766 ZNF143 SP3 ANKRD18CP CCDC180 MFSD14C NCBP1 LOC441454 NUTM2G ZNF782 ENSG00000235494 LOC100499484-C9ORF174 VN1R52P
GH09H097411 1.1 ENCODE 21.9 -398.8 -398838 2.3 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF766 ZNF207 ZNF143 MXD4 REST NCBP1 ZNF782 MFSD14C ZNF322P1 NUTM2G LOC441454 FAM220CP CCDC180 TDRD7 TMOD1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MFSD14C on UCSC Golden Path with GeneCards custom track

Promoters for MFSD14C Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000238479 508 2400 ATF1 ARID4B SIN3A DMAP1 ZBTB7B GLIS2 ATF7 SP3 ZNF518A KAT8

Genomic Locations for MFSD14C Gene

Genomic Locations for MFSD14C Gene
115,792 bases
Minus strand

Genomic View for MFSD14C Gene

Genes around MFSD14C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MFSD14C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MFSD14C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MFSD14C Gene

Proteins for MFSD14C Gene

  • Protein details for MFSD14C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Hippocampus abundant transcript-like protein 2
    Protein Accession:
    Secondary Accessions:
    • Q9BSG7

    Protein attributes for MFSD14C Gene

    134 amino acids
    Molecular mass:
    14477 Da
    Quaternary structure:
    No Data Available
    • Sequence=BC005058; Type=Miscellaneous discrepancy; Note=The sequence differs at the 3 end.; Evidence={ECO:0000305};

neXtProt entry for MFSD14C Gene

Post-translational modifications for MFSD14C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MFSD14C Gene

No data available for DME Specific Peptides for MFSD14C Gene

Domains & Families for MFSD14C Gene

Gene Families for MFSD14C Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for MFSD14C Gene

Suggested Antigen Peptide Sequences for MFSD14C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the major facilitator superfamily.
  • Belongs to the major facilitator superfamily.
genes like me logo Genes that share domains with MFSD14C: view

Function for MFSD14C Gene

Phenotypes From GWAS Catalog for MFSD14C Gene

Gene Ontology (GO) - Molecular Function for MFSD14C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity IBA --
genes like me logo Genes that share ontologies with MFSD14C: view

Phenotypes for MFSD14C Gene

GenomeRNAi human phenotypes for MFSD14C:
genes like me logo Genes that share phenotypes with MFSD14C: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MFSD14C Gene

Localization for MFSD14C Gene

Subcellular locations from UniProtKB/Swiss-Prot for MFSD14C Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MFSD14C gene
Compartment Confidence
cytosol 2
plasma membrane 1
mitochondrion 1
peroxisome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MFSD14C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MFSD14C: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MFSD14C Gene

Pathways & Interactions for MFSD14C Gene

SuperPathways for MFSD14C Gene

No Data Available

Interacting Proteins for MFSD14C Gene

Gene Ontology (GO) - Biological Process for MFSD14C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0055085 transmembrane transport IBA --
genes like me logo Genes that share ontologies with MFSD14C: view

No data available for Pathways by source and SIGNOR curated interactions for MFSD14C Gene

Drugs & Compounds for MFSD14C Gene

No Compound Related Data Available

Transcripts for MFSD14C Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MFSD14C Gene

No ASD Table

Relevant External Links for MFSD14C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MFSD14C Gene

NURSA nuclear receptor signaling pathways regulating expression of MFSD14C Gene:


Evidence on tissue expression from TISSUES for MFSD14C Gene

  • Skin(4.1)
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MFSD14C Gene

Orthologs for MFSD14C Gene

This gene was present in the common ancestor of animals.

Orthologs for MFSD14C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia HIATL2 34
  • 96 (a)
(Canis familiaris)
Mammalia -- 34
  • 24 (a)
(Bos Taurus)
Mammalia HIATL1 34
  • 23 (a)
(Mus musculus)
Mammalia Hiatl1 34
  • 21 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 19 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
(Anolis carolinensis)
Reptilia -- 34
  • 19 (a)
(Danio rerio)
Actinopterygii CU856539.1 34
  • 17 (a)
si:ch211-87m7.2 34
  • 17 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5078 34
  • 14 (a)
CG11537 34
  • 10 (a)
CG17637 34
  • 9 (a)
CG18281 34
  • 8 (a)
(Caenorhabditis elegans)
Secernentea T25D3.4 34
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6723 34
  • 15 (a)
Species where no ortholog for MFSD14C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MFSD14C Gene

Gene Tree for MFSD14C (if available)
Gene Tree for MFSD14C (if available)

Paralogs for MFSD14C Gene

Paralogs for MFSD14C Gene

genes like me logo Genes that share paralogs with MFSD14C: view

Variants for MFSD14C Gene

Sequence variations from dbSNP and Humsavar for MFSD14C Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000048418 -- 96,993,657(+) TCTTG(A/G)AAAAA intron-variant
rs1000050105 -- 96,956,416(+) TTCAT(A/G)AATTA intron-variant
rs1000064461 -- 96,962,545(+) ACTCA(A/G)GAACT intron-variant
rs1000183504 -- 96,951,061(+) AGTCT(C/T)TTAGC intron-variant
rs1000245088 -- 96,961,984(+) TCTAG(A/C)ATATC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MFSD14C Gene

Variant ID Type Subtype PubMed ID
nsv972790 CNV duplication 23825009
nsv972789 CNV duplication 23825009
nsv831662 CNV gain 17160897
nsv831661 CNV loss 17160897
nsv6625 CNV insertion 18451855
nsv520001 CNV loss 19592680
nsv1147999 OTHER inversion 26484159
nsv1075257 CNV deletion 25765185
esv3621177 CNV loss 21293372
esv3621176 CNV loss 21293372
esv2738813 CNV deletion 23290073

Variation tolerance for MFSD14C Gene

Gene Damage Index Score: 3.64; 56.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MFSD14C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MFSD14C Gene

Disorders for MFSD14C Gene

Relevant External Links for MFSD14C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MFSD14C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MFSD14C Gene

Publications for MFSD14C Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for MFSD14C Gene

Sources for MFSD14C Gene

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