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Aliases for MFSD13A Gene

Aliases for MFSD13A Gene

  • Major Facilitator Superfamily Domain Containing 13A 2 3 5
  • Major Facilitator Superfamily Domain-Containing 13A 3 4
  • Transmembrane Protein 180 2 3
  • C10orf77 3 4
  • TMEM180 3 4
  • BA18I14.8 3

External Ids for MFSD13A Gene

Previous HGNC Symbols for MFSD13A Gene

  • C10orf77
  • TMEM180

Summaries for MFSD13A Gene

GeneCards Summary for MFSD13A Gene

MFSD13A (Major Facilitator Superfamily Domain Containing 13A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MFSD13A Gene

Genomics for MFSD13A Gene

Regulatory Elements for MFSD13A Gene

Enhancers for MFSD13A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MFSD13A on UCSC Golden Path with GeneCards custom track

Promoters for MFSD13A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MFSD13A on UCSC Golden Path with GeneCards custom track

Genomic Location for MFSD13A Gene

Chromosome:
10
Start:
102,461,381 bp from pter
End:
102,480,118 bp from pter
Size:
18,738 bases
Orientation:
Plus strand

Genomic View for MFSD13A Gene

Genes around MFSD13A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MFSD13A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MFSD13A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MFSD13A Gene

Proteins for MFSD13A Gene

  • Protein details for MFSD13A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14CX5-MF13A_HUMAN
    Recommended name:
    Transmembrane protein 180
    Protein Accession:
    Q14CX5
    Secondary Accessions:
    • Q6NWM8
    • Q6NWM9
    • Q6PEZ7
    • Q9H679

    Protein attributes for MFSD13A Gene

    Size:
    517 amino acids
    Molecular mass:
    57381 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH67530.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH67531.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB15385.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI12524.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for MFSD13A Gene

Post-translational modifications for MFSD13A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MFSD13A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MFSD13A Gene

Domains & Families for MFSD13A Gene

Protein Domains for MFSD13A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MFSD13A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MFSD13A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MFSD13A Gene

Function for MFSD13A Gene

genes like me logo Genes that share phenotypes with MFSD13A: view

Animal Model Products

  • Taconic Biosciences Mouse Models for MFSD13A

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MFSD13A Gene

Localization for MFSD13A Gene

Subcellular locations from UniProtKB/Swiss-Prot for MFSD13A Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for MFSD13A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MFSD13A: view

No data available for Subcellular locations from COMPARTMENTS for MFSD13A Gene

Pathways & Interactions for MFSD13A Gene

SuperPathways for MFSD13A Gene

No Data Available

Interacting Proteins for MFSD13A Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000238936%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000238936 Q14CX5-MF13A_HUMAN for MFSD13A Gene via STRING IID

Gene Ontology (GO) - Biological Process for MFSD13A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MFSD13A Gene

Drugs & Compounds for MFSD13A Gene

No Compound Related Data Available

Transcripts for MFSD13A Gene

Unigene Clusters for MFSD13A Gene

Transmembrane protein 180:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MFSD13A Gene

No ASD Table

Relevant External Links for MFSD13A Gene

GeneLoc Exon Structure for
MFSD13A
ECgene alternative splicing isoforms for
MFSD13A

Expression for MFSD13A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of MFSD13A Gene:

MFSD13A

SOURCE GeneReport for Unigene cluster for MFSD13A Gene:

Hs.309069
genes like me logo Genes that share expression patterns with MFSD13A: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MFSD13A Gene

Orthologs for MFSD13A Gene

This gene was present in the common ancestor of animals.

Orthologs for MFSD13A Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia TMEM180 34
  • 90.46 (n)
  • 91.49 (a)
TMEM180 35
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mfsd13a 16
Tmem180 35
  • 89 (a)
OneToOne
Tmem180 34
  • 86.59 (n)
  • 88.59 (a)
cow
(Bos Taurus)
Mammalia TMEM180 35
  • 91 (a)
OneToOne
TMEM180 34
  • 89.88 (n)
  • 91.1 (a)
chimpanzee
(Pan troglodytes)
Mammalia TMEM180 35
  • 99 (a)
OneToOne
TMEM180 34
  • 96.7 (n)
  • 96.14 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM180 35
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM180 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM180 34
  • 70.44 (n)
  • 72.37 (a)
TMEM180 35
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM180 35
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.2014 34
tmem180 34
  • 65.87 (n)
  • 69.7 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem180 35
  • 69 (a)
OneToOne
tmem180 34
  • 69.24 (n)
  • 70.12 (a)
worm
(Caenorhabditis elegans)
Secernentea C27H5.4 34
  • 39.46 (n)
  • 27.98 (a)
C27H5.4 35
  • 20 (a)
OneToMany
F10E7.3 35
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 54 (a)
OneToOne
Species where no ortholog for MFSD13A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MFSD13A Gene

ENSEMBL:
Gene Tree for MFSD13A (if available)
TreeFam:
Gene Tree for MFSD13A (if available)

Paralogs for MFSD13A Gene

No data available for Paralogs for MFSD13A Gene

Variants for MFSD13A Gene

Sequence variations from dbSNP and Humsavar for MFSD13A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1984795 -- 102,467,073(+) TGCTC(C/T)GTCGC intron-variant, upstream-variant-2KB
rs2015583 -- 102,467,226(+) AGACG(A/G)GGTTG intron-variant, upstream-variant-2KB
rs2025712 -- 102,470,307(+) CTTGG(C/T)TGGCC intron-variant
rs2025713 -- 102,470,399(+) CCCCA(A/G)CCTTG intron-variant
rs727804 -- 102,459,830(+) CTGTA(G/T)CCCCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MFSD13A Gene

Variant ID Type Subtype PubMed ID
nsv1129499 CNV tandem duplication 24896259

Variation tolerance for MFSD13A Gene

Residual Variation Intolerance Score: 11.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.70; 32.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MFSD13A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MFSD13A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MFSD13A Gene

Disorders for MFSD13A Gene

Relevant External Links for MFSD13A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MFSD13A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MFSD13A

No disorders were found for MFSD13A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MFSD13A Gene

Publications for MFSD13A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65

Products for MFSD13A Gene

Sources for MFSD13A Gene

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