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Aliases for MFSD12 Gene

Aliases for MFSD12 Gene

  • Major Facilitator Superfamily Domain Containing 12 2 3
  • C19orf28 3 4
  • Major Facilitator Superfamily Domain-Containing Protein 12 3
  • Chromosome 19 Open Reading Frame 28 2
  • PP3501 3

External Ids for MFSD12 Gene

Previous HGNC Symbols for MFSD12 Gene

  • C19orf28

Summaries for MFSD12 Gene

GeneCards Summary for MFSD12 Gene

MFSD12 (Major Facilitator Superfamily Domain Containing 12) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MFSD12 Gene

Genomics for MFSD12 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MFSD12 Gene

Start:
3,538,261 bp from pter
End:
3,574,290 bp from pter
Size:
36,030 bases
Orientation:
Minus strand

Genomic View for MFSD12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MFSD12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MFSD12 Gene

No data available for Regulatory Elements for MFSD12 Gene

Proteins for MFSD12 Gene

  • Protein details for MFSD12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NUT3-MFS12_HUMAN
    Recommended name:
    Major facilitator superfamily domain-containing protein 12
    Protein Accession:
    Q6NUT3
    Secondary Accessions:
    • A8MXP7
    • D6W615
    • E9PAJ8
    • Q8N459

    Protein attributes for MFSD12 Gene

    Size:
    480 amino acids
    Molecular mass:
    52075 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MFSD12 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MFSD12 Gene

Proteomics data for MFSD12 Gene at MOPED

Post-translational modifications for MFSD12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MFSD12 Gene

Domains for MFSD12 Gene

Protein Domains for MFSD12 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q6NUT3

UniProtKB/Swiss-Prot:

MFS12_HUMAN :
  • Q6NUT3
Family:
  • Belongs to the major facilitator superfamily.
genes like me logo Genes that share domains with MFSD12: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for MFSD12 Gene

Function for MFSD12 Gene

Phenotypes for MFSD12 Gene

GenomeRNAi human phenotypes for MFSD12:
genes like me logo Genes that share phenotypes with MFSD12: view

Animal Model Products

CRISPR Products

miRNA for MFSD12 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MFSD12

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for MFSD12 Gene

Localization for MFSD12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MFSD12 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for MFSD12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005765 lysosomal membrane IDA 17897319
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MFSD12: view

No data available for Subcellular locations from COMPARTMENTS for MFSD12 Gene

Pathways for MFSD12 Gene

SuperPathways for MFSD12 Gene

No Data Available

Interacting Proteins for MFSD12 Gene

Gene Ontology (GO) - Biological Process for MFSD12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with MFSD12: view

No data available for Pathways by source for MFSD12 Gene

Transcripts for MFSD12 Gene

Unigene Clusters for MFSD12 Gene

Major facilitator superfamily domain containing 12:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MFSD12

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MFSD12 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c
SP1:
SP2: -
SP3:

Relevant External Links for MFSD12 Gene

GeneLoc Exon Structure for
MFSD12
ECgene alternative splicing isoforms for
MFSD12

Expression for MFSD12 Gene

mRNA expression in normal human tissues for MFSD12 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for MFSD12 Gene

SOURCE GeneReport for Unigene cluster for MFSD12 Gene Hs.656901

genes like me logo Genes that share expressions with MFSD12: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for MFSD12 Gene

Orthologs for MFSD12 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MFSD12 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia MFSD12 35
  • 86.02 (n)
  • 85.55 (a)
MFSD12 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mfsd12 35
  • 83.33 (n)
  • 87.01 (a)
Mfsd12 16
Mfsd12 36
  • 83 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MFSD12 35
  • 99.07 (n)
  • 98.37 (a)
MFSD12 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mfsd12 35
  • 82.61 (n)
  • 85.71 (a)
cow
(Bos Taurus)
Mammalia MFSD12 36
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MFSD12 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MFSD12 36
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves C28H19ORF28 35
  • 74.8 (n)
  • 72.73 (a)
MFSD12 36
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mfsd12 35
  • 64.56 (n)
  • 68.69 (a)
Str.19055 35
zebrafish
(Danio rerio)
Actinopterygii mfsd12a 36
  • 59 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011492 35
  • 52.74 (n)
  • 38.46 (a)
worm
(Caenorhabditis elegans)
Secernentea F16H11.1 35
  • 45.36 (n)
  • 42.45 (a)
F16H11.1 36
  • 37 (a)
OneToOne
rice
(Oryza sativa)
Liliopsida Os03g0168000 35
  • 47.62 (n)
  • 35.45 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 46 (a)
OneToOne
Species with no ortholog for MFSD12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MFSD12 Gene

ENSEMBL:
Gene Tree for MFSD12 (if available)
TreeFam:
Gene Tree for MFSD12 (if available)

Paralogs for MFSD12 Gene

genes like me logo Genes that share paralogs with MFSD12: view

No data available for Paralogs for MFSD12 Gene

Variants for MFSD12 Gene

Sequence variations from dbSNP and Humsavar for MFSD12 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs734452 -- 3,558,007(+) GGTCC(C/G)CTGAC upstream-variant-2KB
rs734453 -- 3,557,891(+) CCCGC(A/G)CCACC upstream-variant-2KB
rs734454 -- 3,557,787(-) CGGGG(G/T)TCGCC upstream-variant-2KB
rs1627527 -- 3,555,500(-) GGTTA(C/T)GTTGG intron-variant
rs1638539 -- 3,555,050(+) TGAGG(C/T)CTGCT intron-variant

Relevant External Links for MFSD12 Gene

HapMap Linkage Disequilibrium report
MFSD12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MFSD12 Gene

Disorders for MFSD12 Gene

No disorders were found for MFSD12 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MFSD12 Gene

Publications for MFSD12 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Integral and associated lysosomal membrane proteins. (PMID: 17897319) Schroeder B. … Hasilik A. (Traffic 2007) 3
  4. Novel protein pp3501 mediates the inhibitory effect of sodium butyrate on SH-SY5Y cell proliferation. (PMID: 22441875) Wang Y. … Wu J. (J. Cell. Biochem. 2012) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for MFSD12 Gene

Sources for MFSD12 Gene

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