Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MFSD11 Gene

Aliases for MFSD11 Gene

  • Major Facilitator Superfamily Domain Containing 11 2 3
  • Major Facilitator Superfamily Domain-Containing Protein 11 3 4
  • Protein ET 3 4
  • ET 3 4
  • UNC93-Like Protein MFSD11 3

External Ids for MFSD11 Gene

Previous GeneCards Identifiers for MFSD11 Gene

  • GC17P072245
  • GC17P074733
  • GC17P070161

Summaries for MFSD11 Gene

GeneCards Summary for MFSD11 Gene

MFSD11 (Major Facilitator Superfamily Domain Containing 11) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MFSD11 Gene

Genomics for MFSD11 Gene

Regulatory Elements for MFSD11 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MFSD11 Gene

Start:
76,735,865 bp from pter
End:
76,781,449 bp from pter
Size:
45,585 bases
Orientation:
Plus strand

Genomic View for MFSD11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MFSD11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MFSD11 Gene

Proteins for MFSD11 Gene

  • Protein details for MFSD11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O43934-MFS11_HUMAN
    Recommended name:
    UNC93-like protein MFSD11
    Protein Accession:
    O43934
    Secondary Accessions:
    • O43442
    • Q9NXI5

    Protein attributes for MFSD11 Gene

    Size:
    449 amino acids
    Molecular mass:
    49202 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MFSD11 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MFSD11 Gene

Proteomics data for MFSD11 Gene at MOPED

Post-translational modifications for MFSD11 Gene

  • Glycosylation at Asn40
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for MFSD11 Gene

Domains for MFSD11 Gene

Protein Domains for MFSD11 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MFSD11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O43934

UniProtKB/Swiss-Prot:

MFS11_HUMAN :
  • O43934
Family:
  • Belongs to the unc-93 family.
genes like me logo Genes that share domains with MFSD11: view

No data available for Gene Families for MFSD11 Gene

Function for MFSD11 Gene

Gene Ontology (GO) - Molecular Function for MFSD11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MFSD11: view

Phenotypes for MFSD11 Gene

GenomeRNAi human phenotypes for MFSD11:
genes like me logo Genes that share phenotypes with MFSD11: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MFSD11 Gene

Localization for MFSD11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MFSD11 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MFSD11 Gene COMPARTMENTS Subcellular localization image for MFSD11 gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MFSD11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MFSD11: view

Pathways for MFSD11 Gene

SuperPathways for MFSD11 Gene

No Data Available

Interacting Proteins for MFSD11 Gene

Gene Ontology (GO) - Biological Process for MFSD11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with MFSD11: view

No data available for Pathways by source for MFSD11 Gene

Transcripts for MFSD11 Gene

Unigene Clusters for MFSD11 Gene

Major facilitator superfamily domain containing 11:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MFSD11

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MFSD11 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c · 16d · 16e ^ 17
SP1: - - - -
SP2: - - -
SP3: - -
SP4:
SP5:
SP6: - - - -
SP7: - - - - -
SP8: - - - -

Relevant External Links for MFSD11 Gene

GeneLoc Exon Structure for
MFSD11
ECgene alternative splicing isoforms for
MFSD11

Expression for MFSD11 Gene

mRNA expression in normal human tissues for MFSD11 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MFSD11 Gene

SOURCE GeneReport for Unigene cluster for MFSD11 Gene Hs.73965

genes like me logo Genes that share expressions with MFSD11: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MFSD11 Gene

Orthologs for MFSD11 Gene

This gene was present in the common ancestor of animals.

Orthologs for MFSD11 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MFSD11 35
  • 99.85 (n)
  • 100 (a)
MFSD11 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MFSD11 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MFSD11 35
  • 90.65 (n)
  • 95.55 (a)
MFSD11 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mfsd11 35
  • 87.53 (n)
  • 93.1 (a)
Mfsd11 16
Mfsd11 36
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MFSD11 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MFSD11 36
  • 90 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mfsd11 35
  • 86.93 (n)
  • 93.54 (a)
chicken
(Gallus gallus)
Aves MFSD11 35
  • 76.91 (n)
  • 81.96 (a)
MFSD11 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MFSD11 36
  • 82 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC68544 35
tropical clawed frog
(Silurana tropicalis)
Amphibia mfsd11 35
  • 69.14 (n)
  • 72.13 (a)
Str.14929 35
zebrafish
(Danio rerio)
Actinopterygii LOC799265 35
  • 59.72 (n)
  • 57.85 (a)
mfsd11 36
  • 66 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000311 35
  • 51.7 (n)
  • 48.79 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG18549 35
  • 52.69 (n)
  • 45.3 (a)
CG18549 36
  • 43 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea B0554.5 36
  • 22 (a)
OneToMany
B0554.7 36
  • 21 (a)
OneToMany
C08D8.1 36
  • 30 (a)
OneToMany
C27C12.4 35
  • 44.91 (n)
  • 35.21 (a)
C27C12.4 36
  • 30 (a)
OneToMany
F31D5.1 36
  • 24 (a)
OneToMany
F31D5.2 36
  • 28 (a)
OneToMany
F36G9.3 36
  • 29 (a)
OneToMany
M153.2 36
  • 32 (a)
OneToMany
Y11D7A.3 36
  • 19 (a)
OneToMany
Y37A1A.2 36
  • 18 (a)
OneToMany
Y39B6A.27 36
  • 19 (a)
OneToMany
Y39B6A.29 36
  • 20 (a)
OneToMany
Y39D8A.1 36
  • 23 (a)
OneToMany
Y52E8A.4 36
  • 23 (a)
OneToMany
Y52E8A.6 36
  • 27 (a)
OneToMany
ZK6.6 36
  • 18 (a)
OneToMany
ZK6.8 36
  • 19 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.10944 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 47 (a)
OneToOne
Species with no ortholog for MFSD11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MFSD11 Gene

ENSEMBL:
Gene Tree for MFSD11 (if available)
TreeFam:
Gene Tree for MFSD11 (if available)

Paralogs for MFSD11 Gene

No data available for Paralogs for MFSD11 Gene

Variants for MFSD11 Gene

Sequence variations from dbSNP and Humsavar for MFSD11 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs116719 -- 76,754,249(+) TCTCT(C/T)TAACA intron-variant
rs237050 -- 76,754,419(-) aggcg(C/T)gagtc intron-variant
rs237051 -- 76,746,460(-) tggtc(C/T)acatt intron-variant
rs237052 -- 76,742,575(-) CAGTA(A/C)GCCGA intron-variant
rs471943 -- 76,758,736(+) AAACA(C/T)TCCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MFSD11 Gene

Variant ID Type Subtype PubMed ID
nsv908833 CNV Loss 21882294
nsv833550 CNV Loss 17160897
nsv828110 CNV Gain 20364138

Relevant External Links for MFSD11 Gene

HapMap Linkage Disequilibrium report
MFSD11

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MFSD11 Gene

Disorders for MFSD11 Gene

Relevant External Links for MFSD11

Genetic Association Database (GAD)
MFSD11
genes like me logo Genes that share disorders with MFSD11: view

No data available for UniProtKB/Swiss-Prot for MFSD11 Gene

Publications for MFSD11 Gene

  1. Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene. (PMID: 9358160) Sureau A. … Perbal B. (Nucleic Acids Res. 1997) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Genetic loci for retinal arteriolar microcirculation. (PMID: 23776548) Sim X. … Wong T.Y. (PLoS ONE 2013) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for MFSD11 Gene

Sources for MFSD11 Gene

Back to Top

Content