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Aliases for MFSD11 Gene

Aliases for MFSD11 Gene

  • Major Facilitator Superfamily Domain Containing 11 2 3 5
  • Major Facilitator Superfamily Domain-Containing Protein 11 3 4
  • Protein ET 3 4
  • ET 3 4

External Ids for MFSD11 Gene

Previous GeneCards Identifiers for MFSD11 Gene

  • GC17P072245
  • GC17P074733
  • GC17P070161

Summaries for MFSD11 Gene

GeneCards Summary for MFSD11 Gene

MFSD11 (Major Facilitator Superfamily Domain Containing 11) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MFSD11 Gene

Genomics for MFSD11 Gene

Regulatory Elements for MFSD11 Gene

Enhancers for MFSD11 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MFSD11 on UCSC Golden Path with GeneCards custom track

Promoters for MFSD11 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MFSD11 on UCSC Golden Path with GeneCards custom track

Genomic Location for MFSD11 Gene

76,735,865 bp from pter
76,804,356 bp from pter
68,492 bases
Plus strand

Genomic View for MFSD11 Gene

Genes around MFSD11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MFSD11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MFSD11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MFSD11 Gene

Proteins for MFSD11 Gene

  • Protein details for MFSD11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UNC93-like protein MFSD11
    Protein Accession:
    Secondary Accessions:
    • O43442
    • Q9NXI5

    Protein attributes for MFSD11 Gene

    449 amino acids
    Molecular mass:
    49202 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MFSD11 Gene


neXtProt entry for MFSD11 Gene

Proteomics data for MFSD11 Gene at MOPED

Post-translational modifications for MFSD11 Gene

  • Glycosylation at Asn 40
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for MFSD11 Gene

Domains & Families for MFSD11 Gene

Protein Domains for MFSD11 Gene


Suggested Antigen Peptide Sequences for MFSD11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the unc-93 family.
  • Belongs to the unc-93 family.
genes like me logo Genes that share domains with MFSD11: view

No data available for Gene Families for MFSD11 Gene

Function for MFSD11 Gene

genes like me logo Genes that share phenotypes with MFSD11: view

Animal Model Products

  • Taconic Biosciences Mouse Models for MFSD11

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MFSD11 Gene

Localization for MFSD11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MFSD11 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for MFSD11 Gene COMPARTMENTS Subcellular localization image for MFSD11 gene
Compartment Confidence
plasma membrane 3
cytosol 2
nucleus 2

No data available for Gene Ontology (GO) - Cellular Components for MFSD11 Gene

Pathways & Interactions for MFSD11 Gene

SuperPathways for MFSD11 Gene

No Data Available

Interacting Proteins for MFSD11 Gene

Gene Ontology (GO) - Biological Process for MFSD11 Gene


No data available for Pathways by source and SIGNOR curated interactions for MFSD11 Gene

Drugs & Compounds for MFSD11 Gene

No Compound Related Data Available

Transcripts for MFSD11 Gene

Unigene Clusters for MFSD11 Gene

Major facilitator superfamily domain containing 11:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MFSD11 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b · 16c · 16d · 16e ^ 17
SP1: - - - -
SP2: - - -
SP3: - -
SP6: - - - -
SP7: - - - - -
SP8: - - - -

Relevant External Links for MFSD11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MFSD11 Gene

mRNA expression in normal human tissues for MFSD11 Gene

Protein differential expression in normal tissues from HIPED for MFSD11 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MFSD11 Gene

SOURCE GeneReport for Unigene cluster for MFSD11 Gene Hs.73965

genes like me logo Genes that share expression patterns with MFSD11: view

Protein tissue co-expression partners for MFSD11 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MFSD11 Gene

Orthologs for MFSD11 Gene

This gene was present in the common ancestor of animals.

Orthologs for MFSD11 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia MFSD11 35
  • 90.65 (n)
  • 95.55 (a)
MFSD11 36
  • 96 (a)
(Mus musculus)
Mammalia Mfsd11 35
  • 87.53 (n)
  • 93.1 (a)
Mfsd11 16
Mfsd11 36
  • 93 (a)
(Pan troglodytes)
Mammalia MFSD11 35
  • 99.85 (n)
  • 100 (a)
MFSD11 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Mfsd11 35
  • 86.93 (n)
  • 93.54 (a)
(Bos Taurus)
Mammalia MFSD11 36
  • 95 (a)
(Monodelphis domestica)
Mammalia MFSD11 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia MFSD11 36
  • 90 (a)
(Gallus gallus)
Aves MFSD11 35
  • 76.91 (n)
  • 81.96 (a)
MFSD11 36
  • 81 (a)
(Anolis carolinensis)
Reptilia MFSD11 36
  • 82 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia mfsd11 35
  • 69.14 (n)
  • 72.13 (a)
Str.14929 35
African clawed frog
(Xenopus laevis)
Amphibia MGC68544 35
(Danio rerio)
Actinopterygii LOC799265 35
  • 59.72 (n)
  • 57.85 (a)
mfsd11 36
  • 66 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000311 35
  • 51.7 (n)
  • 48.79 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG18549 35
  • 52.69 (n)
  • 45.3 (a)
CG18549 36
  • 43 (a)
(Caenorhabditis elegans)
Secernentea C27C12.4 35
  • 44.91 (n)
  • 35.21 (a)
B0554.5 36
  • 22 (a)
B0554.7 36
  • 21 (a)
C08D8.1 36
  • 30 (a)
C27C12.4 36
  • 30 (a)
F31D5.1 36
  • 24 (a)
F31D5.2 36
  • 28 (a)
F36G9.3 36
  • 29 (a)
M153.2 36
  • 32 (a)
Y11D7A.3 36
  • 19 (a)
Y37A1A.2 36
  • 18 (a)
Y39B6A.27 36
  • 19 (a)
Y39B6A.29 36
  • 20 (a)
Y39D8A.1 36
  • 23 (a)
Y52E8A.4 36
  • 23 (a)
Y52E8A.6 36
  • 27 (a)
ZK6.6 36
  • 18 (a)
ZK6.8 36
  • 19 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.10944 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 47 (a)
Species with no ortholog for MFSD11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MFSD11 Gene

Gene Tree for MFSD11 (if available)
Gene Tree for MFSD11 (if available)

Paralogs for MFSD11 Gene

No data available for Paralogs for MFSD11 Gene

Variants for MFSD11 Gene

Sequence variations from dbSNP and Humsavar for MFSD11 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs3198672 - 76,778,285(-) AGAAA(A/G)AAATT intron-variant, reference, missense
rs116719 -- 76,754,249(+) TCTCT(C/T)TAACA intron-variant
rs471943 -- 76,758,736(+) AAACA(C/T)TCCAG intron-variant
rs472646 -- 76,765,490(+) caggg(G/T)gttgc intron-variant
rs475186 -- 76,796,809(-) tttgg(G/T)atttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MFSD11 Gene

Variant ID Type Subtype PubMed ID
nsv908833 CNV Loss 21882294
nsv833550 CNV Loss 17160897
nsv828110 CNV Gain 20364138

Variation tolerance for MFSD11 Gene

Residual Variation Intolerance Score: 22.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.33; 26.34% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for MFSD11 Gene

Disorders for MFSD11 Gene

Relevant External Links for MFSD11

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MFSD11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MFSD11 Gene

Publications for MFSD11 Gene

  1. Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene. (PMID: 9358160) Sureau A. … Perbal B. (Nucleic Acids Res. 1997) 2 3 4 67
  2. Genetic loci for retinal arteriolar microcirculation. (PMID: 23776548) Sim X. … Wong T.Y. (PLoS ONE 2013) 3
  3. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MFSD11 Gene

Sources for MFSD11 Gene