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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MFHAS1 Gene

protein-coding GIFtS: 50
GCID: GC08M008680

malignant fibrous histiocytoma amplified sequence 1

Explore 7 diseases affiliated with
MFHAS1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Malignant Fibrous Histiocytoma Amplified Sequence 1¹ ²		Leucine Rich Repeat Containing 65²
MASL1¹ ² ³ ⁵		Malignant Fibrous Histiocytoma-Amplified Sequence 1²
LRRC65¹ ²		MFH-Amplified Sequences With Leucine-Rich Tandem Repeats 1²
Malignant Fibrous Histiocytoma-Amplified Sequence With Leucine-Rich Tandem Repeats 1² ³

External Ids:	HGNC: 16982¹	Entrez Gene: 9258²	Ensembl: ENSG00000147324⁷	OMIM: 605352⁵	UniProtKB: Q9Y4C4³

Export aliases for MFHAS1 gene to outside databases

Previous GC identifers: GC08M008564 GC08M007566

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MFHAS1:

Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant

fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine

zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among

proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH.

(provided by RefSeq, Jul 2008)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.1 NT_077531.4

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MFHAS1 gene promoter:
GR Pax-5 GR-beta HNF-4alpha1 YY1 PPAR-gamma1 HSF2 c-Myb PPAR-gamma2 GR-alpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MFHAS1 promoter sequence

Search SABiosciences Chromatin IP Primers for MFHAS1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MFHAS1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p23.1 Ensembl cytogenetic band: 8p23.1 HGNC cytogenetic band: 8p23.1

MFHAS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MFHAS1 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M008680: view genomic region (about GC identifiers)

Start:	8,640,864 bp from pter	End:	8,751,155 bp from pter
Size:	110,292 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MFHA1_HUMAN, Q9Y4C4 (See protein sequence)

Recommended Name: Malignant fibrous histiocytoma-amplified sequence 1

Size: 1052 amino acids; 116950 Da

Miscellaneous: Tumorigenic in nude mice

Secondary accessions: Q96CI0

Explore the universe of human proteins at neXtProt for MFHAS1: NX_Q9Y4C4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9Y4C4

MFHAS1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_004216.2

ENSEMBL proteins:

ENSP00000276282

Human Recombinant Protein Products for MFHAS1:

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	Uscn ELISAs and CLIAs for MFHAS1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MFHAS1 for domains About GeneDecksing

3 InterPro domains/families:

IPR001611 Leu-rich_rpt

IPR003591 Leu-rich_rpt_typical-subtyp

IPR020859 ROC_GTPase

Graphical View of Domain Structure for InterPro Entry Q9Y4C4

ProtoNet protein and cluster: Q9Y4C4

1 Blocks protein family: IPB001611 Leucine-rich repeat signature

UniProtKB/Swiss-Prot: MFHA1_HUMAN, Q9Y4C4

Similarity: Contains 13 LRR (leucine-rich) repeats

Similarity: Contains 1 Roc domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 GenomeRNAi human phenotype for MFHAS1:

Increased cell death in breast

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MFHAS1

miRNA Products:		OriGene 3'-UTR Clone: MFHAS1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFHAS1
		8/68 QIAGEN miScript miRNA Assays for microRNAs that regulate MFHAS1 (see all 68):
		hsa-miR-576-3p hsa-miR-3130-5p hsa-miR-642a hsa-miR-605 hsa-miR-128 hsa-miR-30d hsa-miR-30a hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: MFHAS1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MFHAS1 (see all 7) OriGene shRNA RFP: MFHAS1 OriGene siRNA: MFHAS1
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		Sirion Biotech Custom design and validation of potent shRNA sequences against MFHAS1

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MFHAS1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MFHAS1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MFHAS1 (NM_004225)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFHAS1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MFHAS1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for MFHAS1 (Q9Y4C4³ ENSP00000276282⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MFHAS1
Search CenterWatch for drugs/clinical trials and news about MFHAS1 / MFHA1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MFHAS1 gene:

NM_004225.2

Unigene Cluster for MFHAS1:

Malignant fibrous histiocytoma amplified sequence 1

Hs.379414 [show with all ESTs]

Unigene Representative Sequence: NM_004225

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000276282(uc003wsj.1) ENST00000521881 ENST00000520715 ENST00000520091

miRNA Products:		OriGene 3'-UTR Clone: MFHAS1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFHAS1
		8/68 QIAGEN miScript miRNA Assays for microRNAs that regulate MFHAS1 (see all 68):
		hsa-miR-576-3p hsa-miR-3130-5p hsa-miR-642a hsa-miR-605 hsa-miR-128 hsa-miR-30d hsa-miR-30a hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: MFHAS1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MFHAS1 (see all 7) OriGene shRNA RFP: MFHAS1 OriGene siRNA: MFHAS1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MFHAS1
		Sirion Biotech Custom design and validation of potent shRNA sequences against MFHAS1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MFHAS1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MFHAS1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MFHAS1 (NM_004225)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFHAS1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFHAS1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MFHAS1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFHAS1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFHAS1

Additional cDNA sequence:

AB016816.1 AK027007.1 AK096504.1 BC014226.2

7 DOTS entries:

DT.309263 DT.86847162 DT.95163888 DT.97838607 DT.116339 DT.121485911 DT.97782560

24/185 AceView cDNA sequences (see all 185):

AA805075 AW731706 BE501097 AI365160 BM665683 AW576433 BX339424 AA906538

BC014226 BX339425 AA911805 AA088779 AA883662 CR625839 AA278545 BG150354

AA989152 AA283137 AA262515 BX426133 BE671977 BQ432068 AW576432 BM756370

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for MFHAS1 About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4	^	5a	·	5b
SP1:
SP2:			-		-				-
SP3:									-

ECgene alternative splicing isoforms for MFHAS1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MFHAS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTTGTGAAT

About this image
See MFHAS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MFHAS1

SOURCE GeneReport for Unigene cluster: Hs.379414

UniProtKB/Swiss-Prot: MFHA1_HUMAN, Q9Y4C4

Tissue specificity: Ubiquitously expressed. Overexpressed in malignant fibrous histiocytomas

SABiosciences Custom PCR Arrays for MFHAS1

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFHAS1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFHAS1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFHAS1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MFHAS1 gene from 4/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MFHAS1⁶ MFHAS1⁶	Uncharacterized protein	91(a) 73(a)	1 ↔ many 1 ↔ many	4(50967952-50986662) 4(50873758-50967804)
lizard (Anolis carolinensis)	Reptilia	MFHAS1⁶	--	72(a)	1 ↔ 1	GL343257.1(1096460-1099669)
African clawed frog (Xenopus laevis)	Amphibia	Xl.20538²	Xenopus laevis transcribed sequence with moderate similarity to protein refNP_004216.1 (H.sapiens) MFH-amplified sequences with leucine-rich tandem repeats 1 [Homo sapiens] less	76.8(n)		CD327089.1
zebrafish (Danio rerio)	Actinopterygii	LOC797005¹	malignant fibrous histiocytoma-amplified sequence 1 homolog less	63.79(n) 68.12(a)		797005 XM_001335166.4 XP_001335202.2

ENSEMBL Gene Tree for MFHAS1 (if available)
TreeFam Gene Tree for MFHAS1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MFHAS1 gene

LRRC7² LRRC2² ERBB2IP² LRRC18² LRRC30² LRRC1² PIDD² LRRIQ4²

SCRIB² SHOC2² LRRD1² LRRC10B² LRRC39² LRRC40² LRRC10²

1 SIMAP similar gene for MFHAS1 using alignment to 2 protein entries: MFHA1_HUMAN (see all proteins):

LRRC57

MFHAS1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs114118146^1,2	F	--	8641504(+)	`TGACAG/CCATAA`	1	--	ds500¹		1		WA	118
rs13031^1,2	C,F,H	--	8641592(-)	`CTTTGG/TGTGAC`	1	--	ds500¹		15		MN NS EA NA WA	1822
rs60951794^1,2	F	--	8641606(+)	`CATTTT/CTGTCA`	1	--	ds500¹		1		WA	118
rs77877563^1,2	F	--	8641613(+)	`GTCATT/ATAATA`	1	--	ds500¹		1		NA	120
rs187540098^1,2		--	8641738(+)	`CTTCCA/CAACTA`	1	--	ds500¹		0	--	--	--	--
rs35854457^1,2	C	--	8641775(+)	`GTGAC-/CATT CAGTT`	1	--	ds500¹		0	--	--	--	--
rs66638210^1,2	C	--	8641777(+)	`GACCA-/TTCA GTTTT`	1	--	ds500¹		1		NA	2
rs189950579^1,2		--	8641818(+)	`GACGCA/GCACAC`	1	--	ds500¹		0	--	--	--	--
rs183276526^1,2		--	8641828(+)	`CACACA/TCGAGA`	1	--	ds500¹		0	--	--	--	--
rs187947650^1,2		--	8641834(+)	`CGAGAA/GCTGTG`	1	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MFHAS1 (8640864 - 8751155 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 21 variations for MFHAS1
     4 CNVs: 62777 70276 9594 2734
     1 Indel: 100265
     15/16 Inversions (see all 16): 37318 37316 37307 37317 37311 37319 37320 37315 37312 37321 37304 37313 37314 37305 37306

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MFHAS1

DNA2.0 Custom Variant and Variant Library Synthesis for MFHAS1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MFHAS1 for disorders About GeneDecksing

OMIM gene information: 605352 OMIM disorders: --

UniProtKB/Swiss-Prot: MFHA1_HUMAN, Q9Y4C4

Note=A chromosomal aberration involving MFHAS1 may be a cause of B-cell lymphoma. Translocation

t(8;14)(p23.1;q21) with a cryptic exon named '14q21 element'. The resulting fusion protein named 'chimeric MASL1' is

tumorigenic in nude mice

7 diseases for MFHAS1: About MalaCards

malignant fibrous histiocytoma fibrous histiocytoma histiocytoma atypical lipomatous tumor

b-cell lymphomas adhd gastric cancer

1 disease from the University of Copenhagen DISEASES database for MFHAS1:

Malignant fibroxanthoma

Human Genome Epidemiology (HuGE) Navigator: MFHAS1 (2 documents)

Export disorders for MFHAS1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MFHAS1 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with MFHAS1)

Utopia: connect your pdf to the dynamic
world of online information

Identification of a novel gene, MASL1, within an amplicon at 8p23.1 detected in malignant fibrous histiocytomas by comparative genomic hybridization. (PubMed id 9973190)^{1, 2, 3, 9} Sakabe T.... Inazawa J. (1999)
MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8. (PubMed id 14691450)^{1, 2} Tagawa H....Seto M. (2004)
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP. (PubMed id 22210626)¹ Mead S....Collinge J. (2012)
Human leucine-rich repeat proteins: a genome-wide bio informatic categorization and functional analysis in innate immunity. (PubMed id 20616063)¹ Ng A.C....Xavier R.J. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)¹ He C....Hunter D.J. (2010)
Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)² Choudhary C.... Mann M. (2009)
Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan. (PubMed id 18846501)¹ Sonuga-Barke E.J....Faraone S.V. (2008)
DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)² Nusbaum C....Lander E.S. (2006)
Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PubMed id 16094384)¹ Tao W.A.... Aebersold R. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 9258	HGNC: 16982	AceView: MFHAS1	Ensembl:ENSG00000147324	euGenes: HUgn9258
ECgene: MFHAS1	H-InvDB: MFHAS1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MFHAS1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for MFHAS1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for MFHAS1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MFHAS1 gene:
Search GeneIP for patents involving MFHAS1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for MFHAS1
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MFHAS1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MFHAS1
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	GenScript Custom Purified and Recombinant Proteins Services for MFHAS1		GenScript cDNA clones with any tag delivered in your preferred vector for MFHAS1
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFHAS1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MFHAS1

Sirion Biotech Customized:

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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes MFHAS1 gene at Home site.

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MFHAS1 Gene

malignant fibrous histiocytoma amplified sequence 1

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Pathways & Interactions
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Export list of displayed genes

MFHAS1 Gene

malignant fibrous histiocytoma amplified sequence 1

Aliasesfor MFHAS1 gene

Summariesfor MFHAS1 gene

Genomic Viewsfor MFHAS1 gene

Proteinsfor MFHAS1 gene

Protein Domains /Familiesfor MFHAS1 gene

Functionfor MFHAS1 gene

Pathways & Interactionsfor MFHAS1 gene

Drugs & Compoundsfor MFHAS1 gene

Transcriptsfor MFHAS1 gene

Expression for MFHAS1 gene

Orthologsfor MFHAS1 gene

Paralogsfor MFHAS1 gene

Genomic Variantsfor MFHAS1 gene

Disorders / Diseasesfor MFHAS1 gene

Publicationsfor MFHAS1 gene

External Searches for MFHAS1 gene

Genome Databases showing MFHAS1 gene

Other Databases showing MFHAS1 gene

Specialized Databases showing MFHAS1 gene

Intellectual Propertyfor MFHAS1 gene

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Aliases
for MFHAS1 gene

Summaries
for MFHAS1 gene

Genomic Views
for MFHAS1 gene

Proteins
for MFHAS1 gene

Protein Domains /
Families
for MFHAS1 gene

Function
for MFHAS1 gene

Pathways & Interactions
for MFHAS1 gene

Drugs & Compounds
for MFHAS1 gene

Transcripts
for MFHAS1 gene

Expression
for MFHAS1 gene

Orthologs
for MFHAS1 gene

Paralogs
for MFHAS1 gene

Genomic Variants
for MFHAS1 gene

Disorders / Diseases
for MFHAS1 gene

Publications
for MFHAS1 gene

Intellectual Property
for MFHAS1 gene

Products
for MFHAS1 gene