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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MFF Gene

protein-coding   GIFtS: 49
GCID: GC02P228189

Mitochondrial Fission Factor

(Previous name: chromosome 2 open reading frame 33)
(Previous symbol: C2orf33)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mitochondrial Fission Factor1 2
C2orf331 2 3
Chromosome 2 Open Reading Frame 331
GL0042

External Ids:    HGNC: 248581   Entrez Gene: 569472   Ensembl: ENSG000001689587   OMIM: 6147855   UniProtKB: Q9GZY83   

Export aliases for MFF gene to outside databases

Previous GC identifers: GC02P227899 GC02P220036


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MFF Gene:
This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded
protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on
chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Mar
2013)

GeneCards Summary for MFF Gene: 
MFF (mitochondrial fission factor) is a protein-coding gene. Diseases associated with MFF include sclerosing keratitis, and elephantiasis. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: MFF_HUMAN, Q9GZY8
Function: Plays a role in mitochondrial and peroxisomal fission

Gene Wiki entry for MFF (Mitochondrial fission factor) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MFF gene promoter:
         C/EBPbeta   MEF-2   Pax-6   MyoD   Meis-1b   MEF-2A   aMEF-2   Meis-1a   MRF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMFF promoter sequence
   Search SABiosciences Chromatin IP Primers for MFF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MFF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q36.3   Ensembl cytogenetic band:  2q36.3   HGNC cytogenetic band: 2q36

MFF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MFF gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P228189:  view genomic region     (about GC identifiers)

Start:
228,189,867 bp from pter      End:
228,222,550 bp from pter
Size:
32,684 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MFF_HUMAN, Q9GZY8 (See protein sequence)
Recommended Name: Mitochondrial fission factor  
Size: 342 amino acids; 38465 Da
Subcellular location: Mitochondrion outer membrane; Single-pass type IV membrane protein
Secondary accessions: Q567U1 Q658R6 Q9BVZ1 Q9H690 Q9NRG8
Alternative splicing: 5 isoforms:  Q9GZY8-1   Q9GZY8-2   Q9GZY8-3   Q9GZY8-4   Q9GZY8-5   (Contains a phosphoserine at position 146)

Explore the universe of human proteins at neXtProt for MFF: NX_Q9GZY8

Explore proteomics data for MFF at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9GZY8

  • MFF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MFF Protein Expression
    REFSEQ proteins (9 alternative transcripts): 
    NP_001263990.1  NP_001263991.1  NP_001263992.1  NP_001263993.1  NP_001263994.1  NP_001263995.1  NP_001263996.1  NP_001263997.1  
    NP_064579.3  

    ENSEMBL proteins: 
     ENSP00000390165   ENSP00000304898   ENSP00000302037   ENSP00000346498   ENSP00000431725  
     ENSP00000432447   ENSP00000386964   ENSP00000415996   ENSP00000386641   ENSP00000338412  
     ENSP00000436920   ENSP00000435354   ENSP00000436289   ENSP00000304134   ENSP00000411386  
     ENSP00000391829   ENSP00000407547   ENSP00000415313   ENSP00000375912  

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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MFF 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion ----
    GO:0005741mitochondrial outer membrane IDA--
    GO:0005777peroxisome IDA18353969
    GO:0032592integral to mitochondrial membrane IDA18353969

    MFF for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008518 FATE/Miff/Tango-11

    Graphical View of Domain Structure for InterPro Entry Q9GZY8

    ProtoNet protein and cluster: Q9GZY8

    UniProtKB/Swiss-Prot: MFF_HUMAN, Q9GZY8
    Similarity: Belongs to the Tango11 family


    MFF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MFF_HUMAN, Q9GZY8
    Function: Plays a role in mitochondrial and peroxisomal fission

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042803protein homodimerization activity IDA--
         
    MFF for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MFF:
     Decreased viability with pacli  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MFF 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MFF

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate MFF:
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    SwitchGear 3'UTR luciferase reporter plasmidMFF 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFF


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MFF

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for MFF (Q9GZY83 ENSP000003020374) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SQSTM1Q135013I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000266mitochondrial fission ISS--
    GO:0001836release of cytochrome c from mitochondria IMP18353969
    GO:0006626protein targeting to mitochondrion IMP--
    GO:0008053mitochondrial fusion IMP--
    GO:0010821regulation of mitochondrion organization IMP18353969

    MFF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MFF

    Search CenterWatch for drugs/clinical trials and news about MFF

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MFF gene (9 alternative transcripts): 
    NM_001277061.1  NM_001277062.1  NM_001277063.1  NM_001277064.1  NM_001277065.1  NM_001277066.1  NM_001277067.1  NM_001277068.1  
    NM_020194.5  

    Unigene Cluster for MFF:

    Mitochondrial fission factor
    Hs.471528  [show with all ESTs]
    Unigene Representative Sequence: NM_001277061
    18/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000423098 ENST00000304593(uc002vot.3 uc021vxu.1) ENST00000476924
    ENST00000489696 ENST00000353339(uc002vos.3) ENST00000354503 ENST00000530359
    ENST00000531278 ENST00000409565 ENST00000452930 ENST00000409616 ENST00000460756
    ENST00000337110(uc002vow.3 uc002voz.3) ENST00000525195 ENST00000470090
    ENST00000534203 ENST00000524634 ENST00000349901
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFF
    1 QIAGEN miScript miRNA Assays for microRNA that regulate MFF:
    hsa-miR-450b-5p
    SwitchGear 3'UTR luciferase reporter plasmidMFF 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFF

    Additional mRNA sequence: 

    AF226049.1 AF246239.1 AF258660.1 AK026137.1 BC000797.1 BC093024.1 NR_102266.1 

    24/43 DOTS entries (see all 43):

    DT.100039364  DT.95095294  DT.91862879  DT.419092  DT.100039362  DT.100889797  DT.100039363  DT.91776269 
    DT.92017025  DT.100889748  DT.100889791  DT.95342457  DT.121013360  DT.91776249  DT.121013432  DT.121013429 
    DT.95342420  DT.100889784  DT.91735333  DT.100889790  DT.40211143  DT.437069  DT.95342398  DT.100889785 

    24/466 AceView cDNA sequences (see all 466):

    NM_020194 AW131824 F37015 BU683953 AA444123 AW004973 BM969628 W74362 
    AA666306 AA451805 CR610466 AI005034 CD515895 BU626027 AI445623 BG924948 
    BM998418 AI342923 AA767495 BM856464 BQ014605 AA548624 BM973677 AW512653 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for MFF (see all 16)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^
    SP1:                                            -                 -     -     -     -                                         -     -     -     -     -     -   
    SP2:                                            -                 -     -     -     -                                         -     -     -     -               
    SP3:                                            -                 -     -     -     -                                         -     -     -     -     -     -   
    SP4:                                                              -     -     -     -                                                     -     -               
    SP5:                                                                                                                                            -               

    ExUns: 11 ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c · 14d · 14e · 14f
    SP1:  -                                                         
    SP2:                                                            
    SP3:  -     -                                                   
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for MFF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MFF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGTGAACAAT
    MFF Expression
    About this image


    See MFF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MFF

    SOURCE GeneReport for Unigene cluster: Hs.471528

    UniProtKB/Swiss-Prot: MFF_HUMAN, Q9GZY8
    Tissue specificity: Highly expressed in heart, kidney, liver, brain, muscle, and stomach

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MFF gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mff1 , 5 mitochondrial fission factor1, 5 91.87(n)1
    94.85(a)1
      1 (42.45 cM)5
    757341  NM_029409.21  NP_083685.21 
     827248905 
    chicken
    (Gallus gallus)
    Aves MFF1 mitochondrial fission factor 81.71(n)
    84.45(a)
      424796  XM_001233529.2  XP_001233530.1 
    lizard
    (Anolis carolinensis)
    Reptilia MFF6
    mitochondrial fission factor
    81(a)
    1 ↔ 1
    3(23430606-23458997)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.314322 Xenopus laevis transcribed sequences 74.08(n)    CF548786.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc660222 hypothetical protein MGC66022 71.93(n)   393508  BC056301.1 


    ENSEMBL Gene Tree for MFF (if available)
    TreeFam Gene Tree for MFF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MFF gene

    MFF for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for MFF (see all 6)
    PGOHUM00000243904 PGOHUM00000243905 PGOHUM00000245103 PGOHUM00000235421 PGOHUM00000241732


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/697 SNPs in MFF are shown (see all 697)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0360284
    A colorectal cancer sample4--see VAR_0360282 E K mis40--------
    rs3678387561,2
    C--220040268(+) TTTGT-/TTTTTA 10 -- int10--------
    rs75765101,2
    C,F,H--227562870(+) GAAATC/ATGAAA 10 -- int1 us2k123Minor allele frequency- A:0.08NS EA NA WA CSA 1970
    rs1493888071,2
    C--227562928(+) AATCAA/C/TGTACT 10 -- int1 us2k10--------
    rs1925631991,2
    --227562966(+) AACTTA/CTGGAA 10 -- int1 us2k10--------
    rs1423364221,2
    C--227563049(+) GGGAG-/AAAAAA 10 -- int1 us2k10--------
    rs76034141,2
    C,F,H--227563195(+) GTTGGC/GATTTC 10 -- int1 us2k18Minor allele frequency- G:0.09NS EA WA NA 776
    rs1827428911,2
    --227563208(+) CATCCA/GCCTTT 10 -- int1 us2k10--------
    rs1447861351,2
    --227563291(+) TAGTAC/GTGAGA 10 -- int1 us2k10--------
    rs1129151611,2
    C,F--227563311(+) TGTACT/CACTAG 10 -- int1 us2k11Minor allele frequency- C:0.04NA 120

    HapMap Linkage Disequilibrium report for MFF (228189867 - 228222550 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for MFF:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2721556CNV Deletion23290073
    esv2721554CNV Deletion23290073
    esv2721558CNV Deletion23290073
    esv2721555CNV Deletion23290073
    esv2721557CNV Deletion23290073


    Human Gene Mutation Database (HGMD): MFF
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MFF
    DNA2.0 Custom Variant and Variant Library Synthesis for MFF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614785    OMIM disorders: --

    11 diseases for MFF:    About MalaCards
    sclerosing keratitis    elephantiasis    hypermobility syndrome    hydrocele
    intestinal volvulus    keratitis    trichuriasis    folliculitis
    filariasis    papillary thyroid carcinoma    thyroiditis

    5 diseases from the University of Copenhagen DISEASES database for MFF:
    Filariasis     Elephantiasis     Hydrocele     Sclerosing keratitis
    Intestinal volvulus

    MFF for disorders           About GeneDecksing


    Export disorders for MFF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MFF gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with MFF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells. (PubMed id 18353969)1, 2, 3 Gandre-Babbe S. and van der Bliek A.M. (2008)
    2. Interchangeable adaptors regulate mitochondrial dynami n assembly for membrane scission. (PubMed id 23530241)1 Koirala S....Shaw J.M. (2013)
    3. 14-3-3 proteins sequester a pool of soluble TRIM32 ubi quitin ligase to repress autoubiquitylation and cytoplasmic body formation. (PubMed id 23444366)1 Ichimura T....Hachiya N. (2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. TRAP1 controls mitochondrial fusion/fission balance th rough Drp1 and Mff expression. (PubMed id 23284813)1 Takamura H....Katayama T. (2012)
    6. Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes. (PubMed id 22499341)1 Shamseldin H.E.... Alkuraya F.S. (2012)
    7. PEX11 proteins attract Mff and human Fis1 to coordinat e peroxisomal fission. (PubMed id 22595523)1 Koch J. and Brocard C. (2012)
    8. Allosteric modulation of Drp1 mechanoenzyme assembly a nd mitochondrial fission by the variable domain. (PubMed id 22334657)1 Strack S. and Cribbs J.T. (2012)
    9. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and ea rly tumor growth. (PubMed id 22878233)1 Guido C....Lisanti M.P. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56947 HGNC: 24858 AceView: C2orf33 Ensembl:ENSG00000168958 euGenes: HUgn56947
    ECgene: MFF H-InvDB: MFF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MFF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MFF gene:
    Search GeneIP for patents involving MFF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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