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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MFAP5 Gene

protein-coding   GIFtS: 56
GCID: GC12M008798

Microfibrillar Associated Protein 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Microfibrillar Associated Protein 51 2     MFAP-52 3
MAGP22 3 5     MP252 3
Microfibril-Associated Glycoprotein 22 3     Microfibril-Associated Glycoprotein-22
MAGP-22 3     Microfibrillar-Associated Protein 52

External Ids:    HGNC: 296731   Entrez Gene: 80762   Ensembl: ENSG000001976147   OMIM: 6011035   UniProtKB: Q133613   

Export aliases for MFAP5 gene to outside databases

Previous GC identifers: GC12M008690 GC12M008689 GC12M008585


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MFAP5 Gene:
This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It
lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are
characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between
these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues
occurs. The structural differences suggest that this encoded protein has some functions that are distinct from
those of MFAP2. (provided by RefSeq, Jul 2008)

GeneCards Summary for MFAP5 Gene: 
MFAP5 (microfibrillar associated protein 5) is a protein-coding gene. Diseases associated with MFAP5 include marfan syndrome, and scleroderma, and among its related super-pathways are Molecules associated with elastic fibres and Collagen formation. GO annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is MFAP2.

UniProtKB/Swiss-Prot: MFAP5_HUMAN, Q13361
Function: Component of the elastin-associated microfibrils

Gene Wiki entry for MFAP5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009714.17  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MFAP5 gene promoter:
         Bach1   RFX1   Brachyury   GCNF   MIF-1   Cdc5   HSF2   GCNF-1   GCNF-2   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMFAP5 promoter sequence
   Search SABiosciences Chromatin IP Primers for MFAP5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MFAP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.1-p12.3   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.1-p12.3

MFAP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MFAP5 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M008798:  view genomic region     (about GC identifiers)

Start:
8,789,942 bp from pter      End:
8,815,484 bp from pter
Size:
25,543 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MFAP5_HUMAN, Q13361 (See protein sequence)
Recommended Name: Microfibrillar-associated protein 5 precursor  
Size: 173 amino acids; 19612 Da
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: B0AZL6 D3DUV1

Explore the universe of human proteins at neXtProt for MFAP5: NX_Q13361

Explore proteomics data for MFAP5 at MOPED 

Post-translational modifications:

  • UniProtKB: Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the
    microfibrils
  • UniProtKB: N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycan heterogeneity at Thr-54:
    HexHexNAc (major) and HexHexNAc + sulfate (minor)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13361

  • MFAP5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MFAP5 Protein Expression
    REFSEQ proteins: NP_003471.1  
    ENSEMBL proteins: 
     ENSP00000441185   ENSP00000444531   ENSP00000352455   ENSP00000411997   ENSP00000379798  
     ENSP00000441492   ENSP00000443839   ENSP00000438525   ENSP00000439289   ENSP00000445799  
     ENSP00000440496  
    Reactome Protein details: Q13361
    Human Recombinant Protein Products for MFAP5: 
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    R&D Systems Recombinant & Natural Proteins for MFAP5 (MAGP-2/MFAP5)
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    Novus Biologicals MFAP5 Proteins
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    Sino Biological Recombinant Protein for MFAP5
    Sino Biological Cell Lysate for MFAP5 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MFAP5 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001527microfibril IEA--
    GO:0005576extracellular region TAS--
    GO:0031012extracellular matrix ----

    MFAP5 for ontologies           About GeneDecksing



    MFAP5 Antibody Products: 
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    ThermoFisher Antibodies for MFAP5
    LSBio Antibodies in human, mouse, rat for MFAP5 

    Assay Products for MFAP5: 
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    Cloud-Clone Corp. ELISAs for MFAP5 
    Cloud-Clone Corp. CLIAs for MFAP5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008673 MAGP

    Graphical View of Domain Structure for InterPro Entry Q13361

    ProtoNet protein and cluster: Q13361

    1 Blocks protein domain: IPB008673 Microfibril-associated glycoprotein

    UniProtKB/Swiss-Prot: MFAP5_HUMAN, Q13361
    Similarity: Belongs to the MFAP family


    MFAP5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MFAP5_HUMAN, Q13361
    Function: Component of the elastin-associated microfibrils

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005201extracellular matrix structural constituent TAS8557636
         
    MFAP5 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MFAP5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MFAP5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MFAP5 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MFAP5 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFAP5
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate MFAP5 (see all 14):
    hsa-miR-374b* hsa-miR-549 hsa-miR-1288 hsa-miR-130a* hsa-miR-586 hsa-miR-23c hsa-miR-545 hsa-miR-583
    SwitchGear 3'UTR luciferase reporter plasmidMFAP5 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MFAP5
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    Gene Editing
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    Clone
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFAP5
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFAP5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MFAP5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Elastic fibre formation
    Molecules associated with elastic fibres0.84
    Elastic fibre formation0.84
    2Collagen biosynthesis and modifying enzymes
    Extracellular matrix organization0.39
    3Notch signaling pathway
    Notch signaling pathway
    4Notch Signaling Pathways
    Notch Signaling Pathways

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for MFAP5
        Notch Signaling Pathways


    1 BioSystems Pathway for MFAP5
        Notch signaling pathway


    3        Reactome Pathways for MFAP5
        Molecules associated with elastic fibres
    Extracellular matrix organization
    Elastic fibre formation



    MFAP5 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MFAP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/14 Interacting proteins for MFAP5 (Q133613 ENSP000003524554) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FBN2P355563, ENSP000002624644I2D: score=2 STRING: ENSP00000262464
    JAG1P785043, ENSP000002549584I2D: score=1 STRING: ENSP00000254958
    JAG2Q9Y2193, ENSP000003281694I2D: score=1 STRING: ENSP00000328169
    MEGF6O750953, ENSP000003489824I2D: score=1 STRING: ENSP00000348982
    VWFP042753, ENSP000002614054I2D: score=1 STRING: ENSP00000261405
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030198extracellular matrix organization TAS--
    GO:0043206extracellular fibril organization IEA--

    MFAP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MFAP5

    Search CenterWatch for drugs/clinical trials and news about MFAP5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MFAP5 gene: 
    NM_003480.2  

    Unigene Cluster for MFAP5:

    Microfibrillar associated protein 5
    Hs.512842  [show with all ESTs]
    Unigene Representative Sequence: NM_003480
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000535411 ENST00000543467 ENST00000359478(uc001qut.1 uc001qus.2 uc009zge.1)
    ENST00000433590 ENST00000396549 ENST00000543369 ENST00000544211 ENST00000535336
    ENST00000538694 ENST00000537009 ENST00000534833 ENST00000544889 ENST00000538107
    ENST00000537128 ENST00000540087
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFAP5
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate MFAP5 (see all 14):
    hsa-miR-374b* hsa-miR-549 hsa-miR-1288 hsa-miR-130a* hsa-miR-586 hsa-miR-23c hsa-miR-545 hsa-miR-583
    SwitchGear 3'UTR luciferase reporter plasmidMFAP5 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MFAP5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MFAP5
    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFAP5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFAP5
    Sirion Biotech Customized lentivirus for stable overexpression of MFAP5 
                         Customized lentivirus expression plasmids for stable overexpression of MFAP5 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for MFAP5
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFAP5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFAP5

    Additional mRNA sequence: 

    AK124368.1 AK290585.1 AK299475.1 AK315807.1 AL833019.1 AY339060.1 BC005901.1 U37283.1 

    13 DOTS entries:

    DT.113811  DT.95159281  DT.95200920  DT.100793261  DT.100793263  DT.100793260  DT.121146226  DT.121146234 
    DT.75102969  DT.92442590  DT.95136801  DT.100736320  DT.100736337 

    24/166 AceView cDNA sequences (see all 166):

    CR603417 BQ010205 BM678444 CB998277 AA694112 BQ019383 BQ009839 AA423884 
    CR619112 CA446239 AI090889 BF439813 CB052517 BQ721977 AA256939 AA236499 
    CA414334 AU280458 AI802950 CA407069 AL833019 W86673 AI741710 CB143610 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MFAP5 expression in normal human tissues (normalized intensities)      MFAP5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATCCTTCTG
    MFAP5 Expression
    About this image


    MFAP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 5 entries
             Mature Cardiac Fibroblasts Myocardium
             Atrioventricular Node
             Coronary Artery Smooth Muscle Cells (CASMC)   
             Cardiac Myocytes   
     
     Fibroblast
             Detroit 551
             Human Prostate Fibroblasts (HPrF)   
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
             Normal Human osteoblasts (NHOST)   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Uncategorized (Uncategorized)    fully expand to see all 2 entries
             PureStem Progenitor E72

    See MFAP5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MFAP5

    SOURCE GeneReport for Unigene cluster: Hs.512842
        SABiosciences Custom PCR Arrays for MFAP5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFAP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MFAP5 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mfap51 , 5 microfibrillar associated protein 51, 5 82.52(n)1
    81.1(a)1
      6 (57.61 cM)5
    505301  NM_015776.21  NP_056591.11 
     1225058455 
    chicken
    (Gallus gallus)
    Aves MFAP51 microfibrillar associated protein 5 57.08(n)
    49.02(a)
      418256  XM_416482.3  XP_416482.2 
    lizard
    (Anolis carolinensis)
    Reptilia MFAP56
    Uncharacterized protein
    45(a)
    1 ↔ 1
    2(81436029-81459930)
    zebrafish
    (Danio rerio)
    Actinopterygii mfap56
    microfibrillar associated protein 5
    30(a)
    1 ↔ 1
    16(14421237-14440378)


    ENSEMBL Gene Tree for MFAP5 (if available)
    TreeFam Gene Tree for MFAP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MFAP5 gene
    MFAP22  
    2 SIMAP similar genes for MFAP5 using alignment to 9 protein entries:     MFAP5_HUMAN (see all proteins):
    MAGP2    MFAP2

    MFAP5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/493 SNPs in MFAP5 are shown (see all 493)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0364304
    A breast cancer sample4--see VAR_0364302 V D mis40--------
    rs123210161,2
    C,F,A,H--8798128(+) AAAAAT/CATATT 1 -- ds500111Minor allele frequency- C:0.08NS EA NA WA CSA 772
    rs1874970421,2
    --8798267(+) TCAAGC/TGATTC 1 -- ds50010--------
    rs1932032521,2
    --8798368(+) TATCAC/TGTTGG 1 -- ds50010--------
    rs1846685461,2
    --8798409(+) TGATCC/TGCCCA 1 -- ds50010--------
    rs1884047741,2
    --8798458(+) CACCAC/TGCCCG 1 -- ds50010--------
    rs1473885771,2
    C--8798466(+) CCGGCC/TGATAC 1 -- ds50010--------
    rs1401255991,2
    C--8798579(+) ATTGG-/AAAAAA 1 -- ut310--------
    rs1927390751,2
    --8798731(+) GTTTCC/TCTAAA 1 -- ut310--------
    rs1835266241,2
    --8798811(+) AGATTA/GTATGC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MFAP5 (8789942 - 8815484 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MFAP5:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2667162CNV Deletion23128226

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MFAP5
    DNA2.0 Custom Variant and Variant Library Synthesis for MFAP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601103    OMIM disorders: --

    3 diseases for MFAP5:    About MalaCards
    marfan syndrome    scleroderma    endotheliitis


    MFAP5 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for MFAP5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    skin fibrosis 83.5 1 15934076 (1)


    Export disorders for MFAP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MFAP5 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MFAP5)
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    1. The exon structure of the human MAGP-2 gene. Similarity with the MAGP-1 gene is confined to two exons encoding a cysteine-rich region. (PubMed id 9792630)1, 2, 3, 9 Hatzinikolas G. and Gibson M.A. (1998)
    2. Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25). (PubMed id 8557636)1, 2, 3 Gibson M.A.... Cleary E.G. (1996)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Microfibril-associate glycoprotein-2 (MAGP-2) promotes angiogenic cell sprouting by blocking notch signaling in endothelial cells. (PubMed id 18417156)1, 9 Albig A.R....Schiemann W.P. (2008)
    5. A gene signature predictive for outcome in advanced o varian cancer identifies a survival factor: microfibril-associated glycoprotein 2. (PubMed id 19962670)1, 9 Mok S.C....Birrer M.J. (2009)
    6. NLF2 gene expression in the endometrium of patients wi th implantation failure after IVF treatment. (PubMed id 22885067)1 Turkyilmaz E....Menevse S. (2012)
    7. Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD. (PubMed id 22171320)2 Halim A.... Larson G. (2011)
    8. Identification of the chondrocyte lineage using micro fibril-associated glycoprotein-2, a novel marker that distinguishes chondrocyte s from synovial cells. (PubMed id 20345228)1 Rapko S....Duguay S. (2010)
    9. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
    10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8076 HGNC: 29673 AceView: MFAP5 Ensembl:ENSG00000197614 euGenes: HUgn8076
    ECgene: MFAP5 H-InvDB: MFAP5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MFAP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MFAP5 gene:
    Search GeneIP for patents involving MFAP5

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