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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MFAP1 Gene

protein-coding   GIFtS: 56
GCID: GC15M044096

Microfibrillar-Associated Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Microfibrillar-Associated Protein 11 2

External Ids:    HGNC: 70321   Entrez Gene: 42362   Ensembl: ENSG000001402597   OMIM: 6002155   UniProtKB: P550813   

Export aliases for MFAP1 gene to outside databases

Previous GC identifers: GC15M039463 GC15M036992 GC15M041675 GC15M041812 GC15M041884 GC15M020919


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MFAP1 Gene: 
MFAP1 (microfibrillar-associated protein 1) is a protein-coding gene. Diseases associated with MFAP1 include prostate cancer, and prostatitis, and among its related super-pathways are Molecules associated with elastic fibres and Collagen formation. GO annotations related to this gene include molecular_function.

UniProtKB/Swiss-Prot: MFAP1_HUMAN, P55081
Function: Component of the elastin-associated microfibrils

Gene Wiki entry for MFAP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MFAP1 gene promoter:
         c-Fos   NF-1   NF-1/L   JunB   Fra-1   FosB   JunD   POU2F1   POU2F1a   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMFAP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MFAP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MFAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15-q21   Ensembl cytogenetic band:  15q15.3   HGNC cytogenetic band: 15q15-q21

MFAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MFAP1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M044096:  view genomic region     (about GC identifiers)

Start:
44,096,690 bp from pter      End:
44,117,000 bp from pter
Size:
20,311 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MFAP1_HUMAN, P55081 (See protein sequence)
Recommended Name: Microfibrillar-associated protein 1  
Size: 439 amino acids; 51958 Da
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: Q86TG6

Explore the universe of human proteins at neXtProt for MFAP1: NX_P55081

Explore proteomics data for MFAP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P55081

  • MFAP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MFAP1 Protein Expression
    REFSEQ proteins: NP_005917.2  
    ENSEMBL proteins: 
     ENSP00000267812  
    Reactome Protein details: P55081
    Human Recombinant Protein Products for MFAP1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for MFAP1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for MFAP1
    GenScript Custom Purified and Recombinant Proteins Services for MFAP1
    Novus Biologicals MFAP1 Protein
    Novus Biologicals MFAP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MFAP1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001527microfibril IDA1374398
    GO:0005576extracellular region TAS--

    MFAP1 for ontologies           About GeneDecksing



    MFAP1 Antibody Products: 
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    Abcam antibodies for MFAP1
    Cloud-Clone Corp. Antibodies for MFAP1 
    ThermoFisher Antibodies for MFAP1
    LSBio Antibodies in human, mouse, rat for MFAP1 

    Assay Products for MFAP1: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for MFAP1 
    Cloud-Clone Corp. CLIAs for MFAP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR009730 MFAP1_C

    Graphical View of Domain Structure for InterPro Entry P55081

    ProtoNet protein and cluster: P55081

    UniProtKB/Swiss-Prot: MFAP1_HUMAN, P55081
    Similarity: Belongs to the MFAP1 family


    MFAP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MFAP1_HUMAN, P55081
    Function: Component of the elastin-associated microfibrils

         Genatlas biochemistry entry for MFAP1:
    microfibrillar associated glycoprotein 1,54kDa,located in non elastic fibrils of ocular zonules

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI--
         
    MFAP1 for ontologies           About GeneDecksing


    Phenotypes:
         7 GenomeRNAi human phenotypes for MFAP1:
     Abundance of large cells with   Cell division defect  Decreased cell number, increas  Decreased influenza A virus in 
     Decreased viability of wild-ty  G0/1 arrest  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MFAP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MFAP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MFAP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MFAP1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFAP1
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate MFAP1:
    hsa-miR-520f hsa-miR-581 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidMFAP1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFAP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MFAP1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Elastic fibre formation
    Molecules associated with elastic fibres0.84
    Elastic fibre formation0.84
    2Collagen biosynthesis and modifying enzymes
    Extracellular matrix organization0.39

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3        Reactome Pathways for MFAP1
        Molecules associated with elastic fibres
    Extracellular matrix organization
    Elastic fibre formation



    MFAP1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MFAP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/55 Interacting proteins for MFAP1 (P550812, 3 ENSP000002678124) via UniProtKB, MINT, STRING, and/or I2D (see all 55)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAGP619812, 3, ENSP000003063304MINT-50820 I2D: score=4 STRING: ENSP00000306330
    PRPF3O433952, ENSP000003153794MINT-8331701 MINT-8336419 STRING: ENSP00000315379
    IKQ131232, ENSP000003963014MINT-8332251 MINT-8337409 STRING: ENSP00000396301
    PRPF38AQ8NAV13, ENSP000002571814I2D: score=2 STRING: ENSP00000257181
    SART1O432902, ENSP000003104484MINT-8336573 STRING: ENSP00000310448
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0030198extracellular matrix organization TAS--

    MFAP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MFAP1

    Search CenterWatch for drugs/clinical trials and news about MFAP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MFAP1 gene: 
    NM_005926.2  

    Unigene Cluster for MFAP1:

    Microfibrillar-associated protein 1
    Hs.61418  [show with all ESTs]
    Unigene Representative Sequence: NM_005926
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267812(uc001zth.1) ENST00000484386
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MFAP1
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate MFAP1:
    hsa-miR-520f hsa-miR-581 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidMFAP1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MFAP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MFAP1
    Clone
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    OriGene clones in human, mouse for MFAP1 (see all 7)
    OriGene ORF clones in mouse, rat for MFAP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MFAP1 (NM_005926)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MFAP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MFAP1
    Sirion Biotech Customized lentivirus for stable overexpression of MFAP1 
                         Customized lentivirus expression plasmids for stable overexpression of MFAP1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MFAP1
    OriGene qSTAR qPCR primer pairs in human, mouse for MFAP1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MFAP1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MFAP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFAP1

    Additional mRNA sequence: 

    AK312867.1 BC023557.2 BC050742.1 U04209.1 

    11 DOTS entries:

    DT.412514  DT.100794705  DT.95376398  DT.91754608  DT.95328562  DT.100794701  DT.100794707  DT.121064892 
    DT.86852240  DT.95376395  DT.97771513 

    24/185 AceView cDNA sequences (see all 185):

    BM681969 BU554087 AW304783 BQ055022 AI969757 AI753612 BM807546 BC050742 
    BP372999 BE504960 AI608759 BX283092 BE467592 BU161359 BG116731 BP349583 
    BU624797 BE348695 BM754487 BM716875 BF197395 CR603002 BM662222 BM550744 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MFAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAAGAAATA
    MFAP1 Expression
    About this image


    See MFAP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MFAP1

    SOURCE GeneReport for Unigene cluster: Hs.61418
        SABiosciences Custom PCR Arrays for MFAP1
    Primer
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    OriGene qPCR primer pairs and template standards for MFAP1
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MFAP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MFAP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MFAP1 gene from 9/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mfap1a1 , 5 microfibrillar-associated protein 1A1, 5 91.19(n)1
    99.54(a)1
      2 (60.40 cM)5
    675321  NM_026220.41  NP_080496.11 
     1214919115 
    chicken
    (Gallus gallus)
    Aves MFAP11 microfibrillar-associated protein 1 80.56(n)
    94.99(a)
      415586  XM_413954.2  XP_413954.2 
    lizard
    (Anolis carolinensis)
    Reptilia MFAP16
    microfibrillar-associated protein 1
    93(a)
    1 ↔ 1
    GL343759.1(177289-186315)
    African clawed frog
    (Xenopus laevis)
    Amphibia mfap1-prov2 microfibrillar-associated protein 1 77.38(n)    BC044036.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc565512 similar to microfibrillar-associated protein 1 76.89(n)   393992  BC052118.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG10173
    Mfap11
    Microfibril-associated protein 11 60(a)3
    60.46(n)1
    61.15(a)1
      62B113
    382561  NM_139422.21  NP_647679.11 
    worm
    (Caenorhabditis elegans)
    Secernentea F43G9.103
    mfap-11
    MICROFIBRILLAR-ASSOCIATED PROTEIN 1
    (ASSOCIATED more3
    Protein MFAP-11
    52(a)3
    54.94(n)1
    48.06(a)1
      I(8646658-8648295)3
    1726611  NM_059939.41  NP_492340.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G085801 microfibrillar-associated protein-like protein 51.7(n)
    44.64(a)
      826419  NM_116927.4  NP_192598.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g02801001 hypothetical protein 52.98(n)
    47.1(a)
      4329017  NM_001053088.1  NP_001046553.1 


    ENSEMBL Gene Tree for MFAP1 (if available)
    TreeFam Gene Tree for MFAP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MFAP1 gene

    MFAP1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MFAP1
    PGOHUM00000248352


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/413 SNPs in MFAP1 are shown (see all 413)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1379442121,2
    --44096256(+) AGGCAC/TTCTAG 1 -- ds50010--------
    rs2002270021,2
    C--44096287(+) CTTTA-/AAAC  
            
    AAACA
    1 -- ds50010--------
    rs720655481,2
    C--44096303(+) CAAAC-/AAAAAA 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs762387601,2
    C,F--44096454(+) TACCTG/ATGTTC 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1841339661,2
    --44096466(+) TCTTTA/GTGTAT 1 -- ds50010--------
    rs1444294121,2
    C--44096520(+) ACACT-/AAACTA 1 -- ds50010--------
    rs1432117411,2
    --44096731(+) TTAATA/TCTTGT 1 -- ds50010--------
    rs1387541821,2
    --44096781(+) TCCTTG/TTTGTG 1 -- ut310--------
    rs10485251,2
    C,H--44096787(-) GAATCA/CCACAA 1 -- ut313Minor allele frequency- C:0.01NS NA 174
    rs774291341,2
    C,F--44096862(+) CAAGCA/GAAAAT 1 -- ut311Minor allele frequency- G:0.02WA 118

    HapMap Linkage Disequilibrium report for MFAP1 (44096690 - 44117000 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MFAP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv742e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MFAP1
    DNA2.0 Custom Variant and Variant Library Synthesis for MFAP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600215    OMIM disorders: --

    2 diseases for MFAP1:    About MalaCards
    prostate cancer    prostatitis


    MFAP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MFAP1
    Human Genome Epidemiology (HuGE) Navigator: MFAP1 (3 documents)

    Export disorders for MFAP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MFAP1 gene, integrated from 9 sources (see all 39):
    (articles sorted by number of sources associating them with MFAP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure of the human gene encoding the associated microfibrillar protein (MFAP1) and localization to chromosome 15q15-q21. (PubMed id 7835894)1, 2, 3 Yeh H.... Rosenbloom J. (1994)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    7. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Dynamic protein-protein interaction wiring of the huma n spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (2012)
    10. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PubMed id 21319273)1 Neganova I....Lako M. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4236 HGNC: 7032 AceView: MFAP1 Ensembl:ENSG00000140259 euGenes: HUgn4236
    ECgene: MFAP1 H-InvDB: MFAP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MFAP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MFAP1 gene:
    Search GeneIP for patents involving MFAP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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