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MEX3D Gene

protein-coding   GIFtS: 47
GCID: GC19M001554

Mex-3 RNA Binding Family Member D

(Previous names: ring finger and KH domain containing 1, mex-3 homolog D...)
(Previous symbol: RKHD1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mex-3 RNA Binding Family Member D1 2     KIAA20313 5
RKHD11 2 3 5     Mex-3 Homolog D (C. Elegans)1
TINO2 3 5     MEX-3D2
Ring Finger And KH Domain Containing 11 2     MEX32
Bcl-2 ARE RNA Binding Protein1 2     OK/SW-cl.42
RNF1932 3     Ring Finger (C3HC4 Type) And KH Domain Containing 12
RING Finger And KH Domain-Containing Protein 12 3     RNA-Binding Protein MEX3D2
RING Finger Protein 1932 3     

External Ids:    HGNC: 167341   Entrez Gene: 3996642   Ensembl: ENSG000001815887   OMIM: 6110095   UniProtKB: Q86XN83   

Export aliases for MEX3D gene to outside databases

Previous GC identifers: GC19M001508 GC19M001328


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MEX3D Gene:
MEX3D (mex-3 RNA binding family member D) is a protein-coding gene. GO annotations related to this gene include AU-rich element binding. An important paralog of this gene is MEX3B.

UniProtKB/Swiss-Prot: MEX3D_HUMAN, Q86XN8
Function: RNA binding protein, may be involved in post-transcriptional regulatory mechanisms (By similarity)

Gene Wiki entry for MEX3D Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_018930.2  NC_000019.9  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the MEX3D gene promoter:
         c-Fos   RP58   AP-1   p53   MyoD   c-Jun   NRSF form 2   ATF6   En-1   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMEX3D promoter sequence
   Search Chromatin IP Primers for MEX3D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MEX3D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

MEX3D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MEX3D gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M001554:  view genomic region     (about GC identifiers)

Start:
1,554,668 bp from pter      End:
1,568,057 bp from pter
Size:
13,390 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MEX3D_HUMAN, Q86XN8 (See protein sequence)
Recommended Name: RNA-binding protein MEX3D  
Size: 651 amino acids; 64883 Da
Sequence caution: Sequence=AAQ04763.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for MEX3D:
2DGR (3D)    
Secondary accessions: A0PJL8 A1L023 E9PAL6 Q71M49
Alternative splicing: 3 isoforms:  Q86XN8-1   Q86XN8-2   Q86XN8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MEX3D: NX_Q86XN8

Explore proteomics data for MEX3D at MOPED

Post-translational modifications: 

  • Phosphorylated (By similarity)1
  • Ubiquitination2 at Lys256
  • Modification sites at PhosphoSitePlus

  • See MEX3D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001167589.1  NP_976049.3  

    ENSEMBL proteins: 
     ENSP00000384398   ENSP00000475059   ENSP00000373476  

    MEX3D Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for MEX3D
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    Novus Biologicals MEX3D Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for MEX3D 

     
    antibodies-online proteins for MEX3D (2 products) 

     
    antibodies-online peptides for MEX3D

    MEX3D Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals MEX3D Antibodies
    Abcam antibodies for MEX3D
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for MEX3D
    antibodies-online antibodies for MEX3D (10 products) 

    MEX3D Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for MEX3D
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for MEX3D 
    antibodies-online kits for MEX3D (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MEX3: Mex-3 homologs
    RNF: RING-type (C3HC4) zinc fingers

    4 InterPro protein domains:
     IPR001841 Znf_RING
     IPR004087 KH_dom
     IPR013083 Znf_RING/FYVE/PHD
     IPR004088 KH_dom_type_1

    Graphical View of Domain Structure for InterPro Entry Q86XN8

    ProtoNet protein and cluster: Q86XN8

    1 Blocks protein domain: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: MEX3D_HUMAN, Q86XN8
    Domain: Binds RNA through its KH domains (By similarity)
    Similarity: Contains 2 KH domains
    Similarity: Contains 1 RING-type zinc finger


    Find genes that share domains with MEX3D           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MEX3D_HUMAN, Q86XN8
    Function: RNA binding protein, may be involved in post-transcriptional regulatory mechanisms (By similarity)

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0017091AU-rich element binding IDA14769789
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with MEX3D           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for MEX3D:
     Decreased Wnt reporter activit  Wnt reporter downregulated 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MEX3D

    miRNA
    Products:
        
    miRTarBase miRNAs that target MEX3D:
    hsa-mir-744-5p (MIRT037573)

    Block miRNA regulation of human, mouse, rat MEX3D using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MEX3D (see all 61):
    hsa-miR-142-5p hsa-miR-548j hsa-miR-3938 hsa-miR-3607-3p hsa-miR-3616-5p hsa-miR-548k hsa-miR-106a hsa-miR-3653
    SwitchGear 3'UTR luciferase reporter plasmidMEX3D 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MEX3D
    Predesigned siRNA for gene silencing in human, mouse, rat MEX3D

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MEX3D

    Clone
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    OriGene clones in human, mouse for MEX3D (see all 9)
    OriGene ORF clones in mouse, rat for MEX3D
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MEX3D (NM_203304)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MEX3D
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MEX3D

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for MEX3D 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEX3D


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MEX3D_HUMAN, Q86XN8: Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly expressed in the
    cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2
    extracellular1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA14769789
    GO:0048471perinuclear region of cytoplasm IDA14769789

    Find genes that share ontologies with MEX3D           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including MEX3D: 
              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for MEX3D

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for MEX3D (Q86XN83 ENSP000003843984) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCL2L11O435213I2D: score=1 
    BCL2ENSP000003296234STRING: ENSP00000329623
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    NDUFS8ENSP000003157744STRING: ENSP00000315774
    UBCENSP000003448184STRING: ENSP00000344818
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010609mRNA localization resulting in posttranscriptional regulation of gene expression NAS14769789
    GO:0061157mRNA destabilization NAS14769789

    Find genes that share ontologies with MEX3D           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MEX3D



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MEX3D gene (2 alternative transcripts): 
    NM_001174118.1  NM_203304.3  

    Unigene Cluster for MEX3D:

    Mex-3 homolog D (C. elegans)
    Hs.436495  [show with all ESTs]
    Unigene Representative Sequence: NM_203304
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000402693(uc010dsn.3) ENST00000605173 ENST00000388824(uc021uml.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MEX3D using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MEX3D (see all 61):
    hsa-miR-142-5p hsa-miR-548j hsa-miR-3938 hsa-miR-3607-3p hsa-miR-3616-5p hsa-miR-548k hsa-miR-106a hsa-miR-3653
    SwitchGear 3'UTR luciferase reporter plasmidMEX3D 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MEX3D
    Predesigned siRNA for gene silencing in human, mouse, rat MEX3D
    Clone
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    OriGene clones in human, mouse for MEX3D (see all 9)
    OriGene ORF clones in mouse, rat for MEX3D
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MEX3D (NM_203304)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MEX3D
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MEX3D
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MEX3D
    OriGene qSTAR qPCR primer pairs in human, mouse for MEX3D
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MEX3D
      QuantiTect SYBR Green Assays in human, mouse, rat MEX3D
      QuantiFast Probe-based Assays in human, mouse, rat MEX3D

    Additional mRNA sequence: 

    AB062435.1 AB107353.1 AF458084.1 AY950680.1 BC113384.1 BC113741.1 DQ225272.1 DQ225273.1 

    3 DOTS entries:

    DT.448151  DT.99955540  DT.75103215 

    Selected AceView cDNA sequences (see all 84):

    BF057375 CK904458 BQ102327 AI360101 AF458084 AI220266 AI245905 BM741563 
    AW663970 AW293848 AI831413 BF059255 NM_203304 BF057619 BF058170 AI650529 
    AW449796 AB107353 CK822929 AW452132 AI768365 CD674037 AI570632 BM023498 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MEX3D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACTGCGCCG
    MEX3D Expression
    About this image

    MEX3D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MEX3D Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.436495

    UniProtKB/Swiss-Prot: MEX3D_HUMAN, Q86XN8
    Tissue specificity: Ubiquitously expressed in all the cell lines and tissues tested

        Pathway & Disease-focused RT2 Profiler PCR Array including MEX3D: 
              Ubiquitin Ligases in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEX3D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MEX3D gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mex3d1 , 5 mex3 homolog D (C. elegans)1, 5 80.25(n)1
    83.05(a)1
      10 (39.72 cM)5
    2374001  NM_198615.21  NP_941017.21 
     803803555 
    chicken
    (Gallus gallus)
    Aves MEX3D1 mex-3 homolog D (C. elegans) 74.94(n)
    72.26(a)
      420082  XM_418202.3  XP_418202.3 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mex3d1 mex-3 RNA binding family member D 60.28(n)
    67.44(a)
      100144717  NM_001123472.1  NP_001116944.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005347221 RNA-binding protein MEX3B-like 61.88(n)
    62.13(a)
      100534722  XM_003201716.2  XP_003201764.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG113606
    --
    30(a)
    1 → many
    4(691768-711276)
    worm
    (Caenorhabditis elegans)
    Secernentea mex-36
    Protein MEX-3, isoform b
    33(a)
    1 → many
    I(127297-134065) WBGene00003229


    ENSEMBL Gene Tree for MEX3D (if available)
    TreeFam Gene Tree for MEX3D (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MEX3D gene
    MEX3B2  MEX3A2  MEX3C2  
    4 SIMAP similar genes for MEX3D using alignment to 2 protein entries:     MEX3D_HUMAN (see all proteins):
    RKHD1    MEX3B    MEX3C    MEX3A

    Find genes that share paralogs with MEX3D           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MEX3D (see all 300)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1429783251,2
    C--1554218(+) CCATG-/TGTC  
            
    TGTCA
    2 -- int10--------
    rs762847961,2
    C,F--1554468(+) GGGGAG/AGACCT 2 -- int14Minor allele frequency- A:0.10CSA WA 124
    rs1121729421,2
    C,F--1554508(+) CCCTCC/TCCCAC 2 -- int12Minor allele frequency- T:0.02CSA NA 122
    rs1491985211,2
    --1554573(+) TGGACC/GACGGA 2 -- int10--------
    rs1146633421,2
    C--1554643(+) GCCCAC/TCCCCC 2 -- int10--------
    rs606364881,2
    C--1554912(+) AAAAAA/-TTAAA 2 -- ut311Minor allele frequency- -:0.00NA 2
    rs1485868871,2
    C--1555033(+) CCCTG-/CCCCCC 2 -- ut310--------
    rs621285241,2
    C--1555042(+) CCTCCA/C/GGCCGC 4 -- ut311CSA 1
    rs115572721,2
    C--1555073(-) AACCAT/CTTATG 2 -- ut312Minor allele frequency- C:0.00NA 4
    rs1922488531,2
    --1555131(+) TGTGCA/GGCCTG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for MEX3D (1554668 - 1568057 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MEX3D (see all 16):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3589n71CNV Loss21882294
    dgv3608n71CNV Loss21882294
    nsv517758CNV Loss19592680
    dgv3607n71CNV Loss21882294
    dgv3601n71CNV Loss21882294
    nsv910292CNV Loss21882294
    nsv910540CNV Loss21882294
    dgv3610n71CNV Loss21882294
    dgv3603n71CNV Loss21882294
    nsv910499CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MEX3D
    DNA2.0 Custom Variant and Variant Library Synthesis for MEX3D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611009    OMIM disorders: --


    Find genes that share disorders with MEX3D           About GenesLikeMe


    Export disorders for MEX3D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MEX3D gene integrated from 10 sources:
    (articles sorted by number of sources associating them with MEX3D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies. (PubMed id 17267406)1, 2, 3 Buchet-Poyau K.... Billaud M. (Nucleic Acids Res. 2007)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein. (PubMed id 14769789)1, 2 Donnini M.... Schiavone N. (J. Biol. Chem. 2004)
    4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    6. Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules. (PubMed id 18779327)1 Courchet J.... Billaud M. (J. Biol. Chem. 2008)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 399664 HGNC: 16734 AceView: RKHD1 Ensembl:ENSG00000181588 euGenes: HUgn399664
    ECgene: MEX3D H-InvDB: MEX3D

    (According to HUGE)
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    HUGE: KIAA2031

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MEX3D Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MEX3D gene:
    Search GeneIP for patents involving MEX3D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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