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METTL9 Gene

protein-coding   GIFtS: 49
GCID: GC16P021610

Methyltransferase Like 9

  See METTL9-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Methyltransferase Like 91 2     PAP12
DORA Reverse Strand Protein 11 2     Methyltransferase-Like Protein 92
DREV2 3     P53 Activated Protein 12
DREV12 3     DORA Reverse Strand Protein3

External Ids:    HGNC: 245861   Entrez Gene: 511082   Ensembl: ENSG000001970067   OMIM: 6093885   UniProtKB: Q9H1A33   

Export aliases for METTL9 gene to outside databases

Previous GC identifers: GC16P021519 GC16P019992


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL9 Gene:
METTL9 (methyltransferase like 9) is a protein-coding gene. Diseases associated with METTL9 include inflammatory bowel disease 1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_187260.1  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the METTL9 gene promoter:
         HOXA9B   HOXA9   RP58   AML1a   HEN1   Egr-2   SRY   Meis-1a   Meis-1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMETTL9 promoter sequence
   Search Chromatin IP Primers for METTL9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.2   Ensembl cytogenetic band:  16p12.2   HGNC cytogenetic band: 16p12.2

METTL9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL9 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P021610:  view genomic region     (about GC identifiers)

Start:
21,608,539 bp from pter      End:
21,668,794 bp from pter
Size:
60,256 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: METL9_HUMAN, Q9H1A3 (See protein sequence)
Recommended Name: Methyltransferase-like protein 9 precursor  
Size: 318 amino acids; 36536 Da
Sequence caution: Sequence=AAD34076.1; Type=Erroneous initiation;
Secondary accessions: Q8NBT8 Q9BWJ7 Q9H1A2 Q9Y390
Alternative splicing: 2 isoforms:  Q9H1A3-1   Q9H1A3-2   

Explore the universe of human proteins at neXtProt for METTL9: NX_Q9H1A3

Explore proteomics data for METTL9 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys51
  • Glycosylation2 at Asn35
  • Modification sites at PhosphoSitePlus

  • See METTL9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001070648.1  NP_001275588.1  NP_001275589.1  NP_057109.3  

    ENSEMBL proteins: 
     ENSP00000454733   ENSP00000350874   ENSP00000379335   ENSP00000457311   ENSP00000456345  
     ENSP00000454239   ENSP00000455285   ENSP00000455720  

    METTL9 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for METTL9

     
    Search eBioscience for Proteins for METTL9 

     
    antibodies-online proteins for METTL9 (2 products) 

     
    antibodies-online peptides for METTL9

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    antibodies-online antibodies for METTL9 

    METTL9 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for METTL9
    Cloud-Clone Corp. CLIAs for METTL9
    Search eBioscience for ELISAs for METTL9 
    antibodies-online kits for METTL9 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007884 DREV_MeTrfase

    Graphical View of Domain Structure for InterPro Entry Q9H1A3

    ProtoNet protein and cluster: Q9H1A3

    UniProtKB/Swiss-Prot: METL9_HUMAN, Q9H1A3
    Similarity: Belongs to the DREV family


    Find genes that share domains with METTL9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008168methyltransferase activity ----
         
    Find genes that share ontologies with METTL9           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for METTL9:
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for METTL9

    miRNA
    Products:
        
    miRTarBase miRNAs that target METTL9:
    hsa-mir-26b-5p (MIRT029221), hsa-mir-192-5p (MIRT026436), hsa-mir-215-5p (MIRT024304)

    Block miRNA regulation of human, mouse, rat METTL9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL9 (see all 31):
    hsa-miR-3685 hsa-miR-137 hsa-miR-520d-5p hsa-miR-340 hsa-miR-507 hsa-miR-650 hsa-miR-141* hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidMETTL9 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for METTL9
    Predesigned siRNA for gene silencing in human, mouse, rat METTL9

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): METTL9 (NM_016025)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL9

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    Browse ESI BIO Cell Lines and PureStem Progenitors for METTL9 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    extracellular1
    lysosome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL9
    Interactions:

        Search GeneGlobe Interaction Network for METTL9

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for METTL9 (Q9H1A33 ENSP000003508744) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHMP6Q96FZ73, ENSP000003174684I2D: score=1 STRING: ENSP00000317468
    UBCENSP000003448184STRING: ENSP00000344818
    CACFD1ENSP000003171214STRING: ENSP00000317121
    MCTP1ENSP000003089574STRING: ENSP00000308957
    MCTP2ENSP000003503774STRING: ENSP00000350377
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    Find genes that share ontologies with METTL9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for METTL9 (METL9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for METTL9 gene (4 alternative transcripts): 
    NM_001077180.2  NM_001288659.1  NM_001288660.1  NM_016025.4  

    Unigene Cluster for METTL9:

    Methyltransferase like 9
    Hs.279583  [show with all ESTs]
    Unigene Representative Sequence: NM_016025
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563026 ENST00000567404 ENST00000358154(uc002dje.3 uc002djf.3)
    ENST00000396014 ENST00000562379 ENST00000570074 ENST00000562961 ENST00000568826
    ENST00000569290 ENST00000564733
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat METTL9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL9 (see all 31):
    hsa-miR-3685 hsa-miR-137 hsa-miR-520d-5p hsa-miR-340 hsa-miR-507 hsa-miR-650 hsa-miR-141* hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidMETTL9 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for METTL9
    Predesigned siRNA for gene silencing in human, mouse, rat METTL9
    Clone
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    OriGene clones in human, mouse for METTL9 (see all 13)
    OriGene ORF clones in mouse, rat for METTL9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): METTL9 (NM_016025)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL9
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for METTL9
    OriGene qSTAR qPCR primer pairs in human, mouse for METTL9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL9
      QuantiTect SYBR Green Assays in human, mouse, rat METTL9
      QuantiFast Probe-based Assays in human, mouse, rat METTL9

    Additional mRNA sequence: 

    AF151839.1 AF497245.1 AJ278577.1 AJ278578.1 AK025565.1 AK074529.1 AK075022.1 AK075237.1 
    AK313077.1 AY093608.1 BC000195.1 

    23 DOTS entries:

    DT.87017121  DT.100770714  DT.100812844  DT.92045174  DT.456420  DT.95308339  DT.120658264  DT.100812841 
    DT.95111096  DT.100812843  DT.95158150  DT.92441608  DT.120658529  DT.100008218  DT.65285197  DT.97763971 
    DT.101962552  DT.120658330  DT.120658472  DT.120658672  DT.120658963  DT.92441604  DT.95158149 

    Selected AceView cDNA sequences (see all 525):

    BI060129 AV711284 BG574285 BG574044 AI088472 BM977500 BU742661 AA157874 
    AA713660 AA186627 AA452616 AK025565 BU621488 CA312474 NM_016025 BM013572 
    BU069216 BE219011 BF057346 BM975260 AW162568 AA450002 BC000195 CD678055 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for METTL9 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d
    SP1:        -     -     -     -     -                                                               
    SP2:        -     -     -     -     -                                                               
    SP3:                                                                                                
    SP4:                                -                                                               
    SP5:                                -     -     -                                                   


    ECgene alternative splicing isoforms for METTL9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    METTL9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTAATAAACT
    METTL9 Expression
    About this image

    METTL9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    METTL9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.279583
        Custom PCR Arrays for METTL9
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for METTL9 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mettl91 , 5 methyltransferase like 91, 5 92.87(n)1
    97.17(a)1
      7 (65.07 cM)5
    590521  NM_021554.21  NP_067529.21 
     1210344455 
    chicken
    (Gallus gallus)
    Aves METTL91 methyltransferase like 9 83.07(n)
    87.94(a)
      416623  NM_001006172.1  NP_001006172.1 
    lizard
    (Anolis carolinensis)
    Reptilia METTL96
    methyltransferase like 9
    85(a)
    1 ↔ 1
    GL343507.1(4786-30440)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC538362 hypothetical protein MGC53836 75.39(n)    BC045080.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mettl91 methyltransferase like 9 58.2(n)
    56.76(a)
      768200  NM_001077342.1  NP_001070810.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG53391 CG5339 46.35(n)
    39.45(a)
      37794  NM_138002.3  NP_611846.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T03G11.61 T03G11.6 49.43(n)
    41.44(a)
      188034  NM_076479.5  NP_508880.2 


    ENSEMBL Gene Tree for METTL9 (if available)
    TreeFam Gene Tree for METTL9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for METTL9 gene
    1 SIMAP similar gene for METTL9 using alignment to 7 protein entries:     METL9_HUMAN (see all proteins):
    PAP1

    Find genes that share paralogs with METTL9           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for METTL9 (see all 782)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs735458671,2
    C,F--21608939(+) CACTCT/CATAGC 2 -- us2k12Minor allele frequency- C:0.09WA 120
    rs1915752711,2
    --21609055(+) TGACAC/GAGTTG 2 -- us2k10--------
    rs1407064551,2
    --21609060(+) GAGTTG/TCTTTG 2 -- us2k10--------
    rs1829788001,2
    --21609125(+) GTTATC/TGGACT 2 -- us2k10--------
    rs1459146231,2
    --21609160(+) ACTTGA/GGCCAG 2 -- us2k10--------
    rs1945491,2
    C,H--21609377(+) CTAATA/GAAAGA 2 -- us2k115Minor allele frequency- G:0.00NS NA WA CSA EA 553
    rs559389931,2
    --21609631(+) AGCCAC/TTGCAC 2 -- us2k10--------
    rs1945501,2
    C--21609793(+) CAAAAG/TGCTTA 2 -- us2k12Minor allele frequency- T:0.07NA EA 122
    rs1945511,2
    C--21609840(+) TTCTGG/ATGCAG 2 -- us2k14Minor allele frequency- A:0.05MN NA EA 1802
    rs1929197091,2
    --21609904(+) TCCCAC/TGAAAT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for METTL9 (21608539 - 21668794 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for METTL9 (see all 36):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv348n27CNV Loss19166990
    dgv2n29CNV Loss16826518
    nsv471086CNV Loss18288195
    dgv2644n71CNV Loss21882294
    dgv116e55CNV Loss17911159
    dgv2642n71CNV Loss21882294
    esv2751552CNV Loss17911159
    nsv457460CNV Loss19166990
    esv34544CNV Gain17911159
    dgv2643n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing METTL9
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609388    OMIM disorders: --

    1 disease for METTL9:    
    About MalaCards
    inflammatory bowel disease 1


    Find genes that share disorders with METTL9           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: METTL9 (2 documents)

    Export disorders for METTL9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for METTL9 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with METTL9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function. (PubMed id 11132146)1, 2, 3 Bates E.E.M.... Lebecque S. (Immunogenetics 2000)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    3. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    5. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    6. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    7. Effects of exogenous p53 transfection on the gene expression in the human brain glioma cell line U251. (PubMed id 16413759)1 Shu K.X.... Wei J.M. (Colloids Surf. B Biointerfaces 2006)
    8. Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development. (PubMed id 16837177)1 Shu K.X....Li B. (Colloids Surf B Biointerfaces 2006)
    9. A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. (PubMed id 16730941)1 Tsang H.T.H....Sanderson C.M. (Genomics 2006)
    10. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (DNA Res. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51108 HGNC: 24586 AceView: DREV1 Ensembl:ENSG00000197006 euGenes: HUgn51108
    ECgene: METTL9 H-InvDB: METTL9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for METTL9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for METTL9 gene:
    Search GeneIP for patents involving METTL9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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