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METTL8 Gene

protein-coding   GIFtS: 42
GCID: GC02M172173

Methyltransferase Like 8

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disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Methyltransferase Like 81 2
Tension-Induced/Inhibited Protein1 2
TIP2
Methyltransferase-Like Protein 82
EC 2.1.1.-3

External Ids:    HGNC: 258561   Entrez Gene: 798282   Ensembl: ENSG000001236007   OMIM: 6095255   UniProtKB: Q9H8253   

Export aliases for METTL8 gene to outside databases

Previous GC identifers: GC02M171888 GC02M164059


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL8 Gene:
METTL8 (methyltransferase like 8) is a protein-coding gene. GO annotations related to this gene include methyltransferase activity. An important paralog of this gene is METTL2B.

UniProtKB/Swiss-Prot: METL8_HUMAN, Q9H825
Function: Probable methyltransferase (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the METTL8 gene promoter:
         c-Fos   AP-1   AML1a   HOXA3   Evi-1   S8   PPAR-gamma1   PPAR-gamma2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMETTL8 promoter sequence
   Search Chromatin IP Primers for METTL8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

METTL8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL8 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M172173:  view genomic region     (about GC identifiers)

Start:
172,173,912 bp from pter      End:
172,291,312 bp from pter
Size:
117,401 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: METL8_HUMAN, Q9H825 (See protein sequence)
Recommended Name: Methyltransferase-like protein 8  
Size: 291 amino acids; 33387 Da
Subunit: Interacts with EP300 (By similarity)
Sequence caution: Sequence=AAH25250.1; Type=Erroneous initiation; Sequence=AAX93077.1; Type=Erroneous gene model
prediction;
Secondary accessions: Q53TM9 Q53TQ0
Alternative splicing: 2 isoforms:  Q9H825-1   Q9H825-2   

Explore the universe of human proteins at neXtProt for METTL8: NX_Q9H825

Explore proteomics data for METTL8 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See METTL8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079046.2  
    ENSEMBL proteins: 
     ENSP00000364407   ENSP00000409025   ENSP00000407180   ENSP00000376382   ENSP00000376377  
     ENSP00000404646   ENSP00000411589   ENSP00000411942  

    METTL8 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for METTL8

     
    Search eBioscience for Proteins for METTL8 

     
    antibodies-online proteins for METTL8 (3 products) 

     
    Search antibodies-online for peptides for METTL8

    METTL8 Antibody Products:

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    Search ThermoFisher Antibodies for METTL8
    antibodies-online antibodies for METTL8 (2 products) 

    METTL8 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for METTL8
    Cloud-Clone Corp. CLIAs for METTL8
    Search eBioscience for ELISAs for METTL8 
    antibodies-online kits for METTL8 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026113 MeTrfase

    Graphical View of Domain Structure for InterPro Entry Q9H825

    ProtoNet protein and cluster: Q9H825

    UniProtKB/Swiss-Prot: METL8_HUMAN, Q9H825
    Similarity: Belongs to the methyltransferase superfamily. METL family


    Find genes that share domains with METTL8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: METL8_HUMAN, Q9H825
    Function: Probable methyltransferase (By similarity)

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004402histone acetyltransferase activity ----
    GO:0008168methyltransferase activity IEA--
         
    Find genes that share ontologies with METTL8           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for METTL8

    miRNA
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    Block miRNA regulation of human, mouse, rat METTL8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL8 (see all 116):
    hsa-miR-140-5p hsa-miR-548j hsa-miR-485-3p hsa-miR-605 hsa-miR-128 hsa-miR-138-2* hsa-miR-342-3p hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmidMETTL8 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for METTL8
    Predesigned siRNA for gene silencing in human, mouse, rat METTL8

    Gene Editing
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    Sino Biological Human cDNA Clone for METTL8
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL8

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    Browse ESI BIO Cell Lines and PureStem Progenitors for METTL8 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    METL8_HUMAN, Q9H825: Cytoplasm (By similarity). Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    nucleus2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with METTL8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL8
    Interactions:

        Search GeneGlobe Interaction Network for METTL8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for METTL8 (Q9H8253 ENSP000003644074) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=2 
    HIST1H4BP628053I2D: score=2 
    HIST1H4CP628053I2D: score=2 
    HIST1H4DP628053I2D: score=2 
    HIST1H4EP628053I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007519skeletal muscle tissue development ----
    GO:0008152metabolic process ----
    GO:0016573histone acetylation ----
    GO:0045444fat cell differentiation ----

    Find genes that share ontologies with METTL8           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for METTL8 (METL8)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for METTL8 gene: 
    NM_024770.3  

    Unigene Cluster for METTL8:

    Methyltransferase like 8
    Hs.135146  [show with all ESTs]
    Unigene Representative Sequence: NM_024770
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000375258 ENST00000447486(uc002ugu.4 uc002ugt.4 uc002ugs.4 uc010zdo.2 uc010zdp.2)
    ENST00000483284 ENST00000463392 ENST00000438609 ENST00000392604 ENST00000477130
    ENST00000464491 ENST00000470773 ENST00000460188 ENST00000392599 ENST00000460539
    ENST00000462821 ENST00000442778 ENST00000453846 ENST00000442541
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat METTL8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL8 (see all 116):
    hsa-miR-140-5p hsa-miR-548j hsa-miR-485-3p hsa-miR-605 hsa-miR-128 hsa-miR-138-2* hsa-miR-342-3p hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmidMETTL8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for METTL8
    Predesigned siRNA for gene silencing in human, mouse, rat METTL8
    Clone
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    OriGene clones in human, mouse for METTL8 (see all 9)
    OriGene ORF clones in mouse, rat for METTL8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: METTL8 (NM_024770)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL8
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for METTL8
    OriGene qSTAR qPCR primer pairs in human, mouse for METTL8
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL8
      QuantiTect SYBR Green Assays in human, mouse, rat METTL8
      QuantiFast Probe-based Assays in human, mouse, rat METTL8

    Additional mRNA sequence: 

    AK023396.1 AK024046.1 AK055616.1 AK093218.1 AK124092.1 AK292108.1 AK297141.1 BC025250.1 

    22 DOTS entries:

    DT.86997009  DT.407185  DT.101982024  DT.97838592  DT.95101199  DT.92024775  DT.100022235  DT.70104232 
    DT.100782997  DT.120951382  DT.100727664  DT.100782995  DT.100782998  DT.120951406  DT.120951413  DT.121021771 
    DT.97791154  DT.97838593  DT.100782996  DT.306237  DT.91639184  DT.95190643 

    Selected AceView cDNA sequences (see all 46):

    AK124092 CB127485 CR614132 CR612022 AI273419 CR595622 BU528736 AL560412 
    BG193942 AA041347 BM553092 AX747996 AU143384 BP376293 AL543410 AV721082 
    NM_024770 AK093218 BC025250 AA888485 AI096740 CB113524 AK024046 BP342737 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for METTL8    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:                    -                       -                                 
    SP2:                    -                       -     -                           
    SP3:                                            -                                 
    SP4:                                                                              
    SP5:              -     -     -                                                   


    ECgene alternative splicing isoforms for METTL8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    METTL8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGTGGTTC
    METTL8 Expression
    About this image

    METTL8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    METTL8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.135146
        Custom PCR Arrays for METTL8
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for METTL8 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mettl81 , 5 methyltransferase like 81, 5 79.5(n)1
    75.19(a)1
      2 (42.34 cM)5
    2280191  NM_145524.31  NP_663499.21 
     709645615 
    chicken
    (Gallus gallus)
    Aves METTL81 methyltransferase like 8 72.35(n)
    67.94(a)
      424154  XM_004942739.1  XP_004942796.1 
    lizard
    (Anolis carolinensis)
    Reptilia METTL86
    methyltransferase like 8
    56(a)
    1 ↔ 1
    GL343353.1(987461-1023210)
    zebrafish
    (Danio rerio)
    Actinopterygii mettl81 methyltransferase like 8 60.12(n)
    59.51(a)
      100148927  NM_001007336.1  NP_001007337.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta metl6
    methyltransferase-like
    40(a)
    1 → many
    3L(1637942-1639235)
    worm
    (Caenorhabditis elegans)
    Secernentea Y53F4B.426
    Protein Y53F4B.42 (Y53F4B.42) mRNA, complete cds
    40(a)
    1 → many
    II(14969902-14971652) WBGene00044720
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ABP1406
    AdoMet-dependent tRNA methyltransferase and actin ...
    18(a)
    1 → many
    XV(784857-786744) YOR239W


    ENSEMBL Gene Tree for METTL8 (if available)
    TreeFam Gene Tree for METTL8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for METTL8 gene
    METTL2B2  METTL62  METTL2A2  
    4 SIMAP similar genes for METTL8 using alignment to 7 protein entries:     METL8_HUMAN (see all proteins):
    FLJ13984    METTL2B    METTL2A    METTL6

    Find genes that share paralogs with METTL8           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for METTL8
    PGOHUM00000239359


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for METTL8 (see all 2196)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1887302231,2
    --172173453(+) CGATCA/GCATTC 1 -- ds50010--------
    rs1932973851,2
    --172173471(+) CAAGCA/GTTCTG 1 -- ds50010--------
    rs1842154651,2
    --172173563(+) GTTGCA/TTGTGC 1 -- ds50010--------
    rs1883592601,2
    --172173609(+) CCCCAC/TTAATG 1 -- ds50010--------
    rs1431203901,2
    --172173731(+) TTTTGA/GAACAA 1 -- ds50010--------
    rs1811713431,2
    --172173740(+) AACCAA/GCACTT 1 -- ds50010--------
    rs1841937711,2
    --172173752(+) ATATAC/TAAAGG 1 -- ds50010--------
    rs739761421,2
    C,F--172173785(+) TCTGCG/ATTTTC 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1889177451,2
    --172173977(+) CCCGCC/TCTGGG 1 -- ut310--------
    rs1816988221,2
    --172174026(+) AAAGAA/TAAAGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for METTL8 (172173912 - 172291312 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for METTL8: --
    Human Gene Mutation Database (HGMD): METTL8
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing METTL8
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609525    OMIM disorders: --


    Find genes that share disorders with METTL8           About GenesLikeMe


    Export disorders for METTL8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for METTL8 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with METTL8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation. (PubMed id 15992539)1, 3 Jakkaraju S....Schuger L. (Dev. Cell 2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Multiple loci influencing hippocampal degeneration identified by genome scan. (PubMed id 22745009)1 Melville S.A....Farrer L.A. (Ann. Neurol. 2012)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    7. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79828 HGNC: 25856 AceView: FLJ13984 Ensembl:ENSG00000123600 euGenes: HUgn79828
    ECgene: METTL8 H-InvDB: METTL8

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for METTL8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for METTL8 gene:
    Search GeneIP for patents involving METTL8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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