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Aliases for METTL24 Gene

Aliases for METTL24 Gene

  • Methyltransferase Like 24 2 3
  • C6orf186 3 4
  • Chromosome 6 Open Reading Frame 186 2
  • Methyltransferase-Like Protein 24 3
  • UPF0624 Protein C6orf186 3
  • EC 2.1.1.- 4
  • DJ71D21.2 3

External Ids for METTL24 Gene

Previous Symbols for METTL24 Gene

  • C6orf186

Summaries for METTL24 Gene

GeneCards Summary for METTL24 Gene

METTL24 (Methyltransferase Like 24) is a Protein Coding gene. GO annotations related to this gene include methyltransferase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for METTL24 Gene

Genomics for METTL24 Gene

Genomic Location for METTL24 Gene

Start:
110,245,928 bp from pter
End:
110,358,272 bp from pter
Size:
112,345 bases
Orientation:
Minus strand

Genomic View for METTL24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for METTL24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for METTL24 Gene

No data available for Regulatory Elements for METTL24 Gene

Proteins for METTL24 Gene

  • Protein details for METTL24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JXM2-MET24_HUMAN
    Recommended name:
    Methyltransferase-like protein 24
    Protein Accession:
    Q5JXM2
    Secondary Accessions:
    • Q6ZSU5

    Protein attributes for METTL24 Gene

    Size:
    366 amino acids
    Molecular mass:
    41330 Da
    Quaternary structure:
    No Data Available

neXtProt entry for METTL24 Gene

Proteomics data for METTL24 Gene at MOPED

Post-translational modifications for METTL24 Gene

No Post-translational modifications

Other Protein References for METTL24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for METTL24 Gene

Domains for METTL24 Gene

Protein Domains for METTL24 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

MET24_HUMAN
Family:
  • Belongs to the methyltransferase superfamily.:
    • Q5JXM2
genes like me logo Genes that share domains with METTL24: view

No data available for Gene Families for METTL24 Gene

Function for METTL24 Gene

Enzyme Numbers (IUBMB) for METTL24 Gene

Gene Ontology (GO) - Molecular Function for METTL24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with METTL24: view

Phenotypes for METTL24 Gene

GenomeRNAi human phenotypes for METTL24:
genes like me logo Genes that share phenotypes with METTL24: view

No data available for Molecular function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for METTL24 Gene

Localization for METTL24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for METTL24 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for METTL24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with METTL24: view

Pathways for METTL24 Gene

SuperPathways for METTL24 Gene

No Data Available

Interacting Proteins for METTL24 Gene

Gene Ontology (GO) - Biological Process for METTL24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with METTL24: view

No data available for Pathways by source for METTL24 Gene

Transcripts for METTL24 Gene

mRNA/cDNA for METTL24 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for METTL24 Gene

Methyltransferase like 24:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for METTL24 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9
SP1: -
SP2: - - -
SP3: - -

Relevant External Links for METTL24 Gene

GeneLoc Exon Structure for
METTL24
ECgene alternative splicing isoforms for
METTL24

Expression for METTL24 Gene

mRNA expression in normal human tissues for METTL24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for METTL24 Gene

SOURCE GeneReport for Unigene cluster for METTL24 Gene Hs.722171

genes like me logo Genes that share expressions with METTL24: view

Orthologs for METTL24 Gene

This gene was present in the common ancestor of chordates.

Orthologs for METTL24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia METTL24 36
  • 98 (n)
  • 95.9 (a)
METTL24 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C9H6orf186 36
  • 88.71 (n)
  • 87.43 (a)
C9H6orf186 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia METTL24 36
  • 90.53 (n)
  • 92.42 (a)
METTL24 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mettl24 36
  • 80.94 (n)
  • 81.77 (a)
Mettl24 16
Mettl24 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia METTL24 37
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia METTL24 37
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mettl24 36
  • 81.68 (n)
  • 81.77 (a)
chicken
(Gallus gallus)
Aves C3H6ORF186 36
  • 73.23 (n)
  • 70.75 (a)
METTL24 37
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia METTL24 37
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mettl24 36
  • 62.69 (n)
  • 65.07 (a)
zebrafish
(Danio rerio)
Actinopterygii METTL24 37
  • 39 (a)
OneToOne
Species with no ortholog for METTL24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for METTL24 Gene

ENSEMBL:
Gene Tree for METTL24 (if available)
TreeFam:
Gene Tree for METTL24 (if available)

Paralogs for METTL24 Gene

No data available for Paralogs for METTL24 Gene

Variants for METTL24 Gene

Sequence variations from dbSNP and Humsavar for METTL24 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs714693 -- 110,321,458(+) ATAGT(C/T)CTCAA intron-variant
rs756487 -- 110,353,909(+) TGTAA(C/T)CATAG intron-variant
rs761586 -- 110,332,497(-) ACTGT(A/G)TAGTT intron-variant
rs976471 -- 110,337,982(-) AGCAG(C/T)AAAAC intron-variant
rs997865 -- 110,335,462(+) TCCAT(C/T)CATAA intron-variant

Relevant External Links for METTL24 Gene

HapMap Linkage Disequilibrium report
METTL24

No data available for Structural Variations from Database of Genomic Variants (DGV) for METTL24 Gene

Disorders for METTL24 Gene

No disorders were found for METTL24 Gene.

No data available for UniProtKB/Swiss-Prot for METTL24 Gene

Publications for METTL24 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for METTL24 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate METTL24
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for METTL24
    • Block miRNA regulation of METTL24 using miScript Target Protectors

    Sources for METTL24 Gene

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