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METTL23 Gene

protein-coding   GIFtS: 40
GCID: GC17P074723

Methyltransferase Like 23

(Previous name: chromosome 17 open reading frame 95)
(Previous symbol: C17orf95)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Methyltransferase Like 231 2
C17orf951 2 3 5
Chromosome 17 Open Reading Frame 951
Methyltransferase-Like Protein 232
EC 2.1.1.-3

External Ids:    HGNC: 269881   Entrez Gene: 1245122   Ensembl: ENSG000001810387   OMIM: 6152625   UniProtKB: Q86XA03   

Export aliases for METTL23 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL23 Gene:
METTL23 (methyltransferase like 23) is a protein-coding gene. Diseases associated with METTL23 include malaria. GO annotations related to this gene include methyltransferase activity. An important paralog of this gene is ENSG00000267168.

UniProtKB/Swiss-Prot: MET23_HUMAN, Q86XA0
Function: Probable methyltransferase (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for METTL23
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for METTL23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.2

METTL23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL23 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P074723:  view genomic region     (about GC identifiers)

Start:
74,722,912 bp from pter      End:
74,730,018 bp from pter
Size:
7,107 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MET23_HUMAN, Q86XA0 (See protein sequence)
Recommended Name: Methyltransferase-like protein 23  
Size: 190 amino acids; 21469 Da
Subunit: Interacts with HSPA5, HSP90B1, TUBULIN, UGGT1 and UGGT2
Sequence caution: Sequence=AAH45819.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: H9ZYJ0

Explore the universe of human proteins at neXtProt for METTL23: NX_Q86XA0

Explore proteomics data for METTL23 at MOPED


See METTL23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (6 alternative transcripts): 
NP_001073979.3  NP_001193912.1  NP_001193913.1  NP_001193914.1  NP_001193915.1  NP_001193916.1  

ENSEMBL proteins: 
 ENSP00000464965   ENSP00000466614   ENSP00000467527   ENSP00000468386   ENSP00000466938  
 ENSP00000467503   ENSP00000466203   ENSP00000468704   ENSP00000465890   ENSP00000341543  
 ENSP00000465430   ENSP00000465959   ENSP00000467101  

METTL23 Human Recombinant Protein Products:

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OriGene Custom MassSpec
OriGene Custom Protein Services for METTL23
GenScript Custom Purified and Recombinant Proteins Services for METTL23
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
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Cloud-Clone Corp. Proteins for METTL23

METTL23 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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OriGene Custom Antibody Services for METTL23
Search for Antibodies for METTL23 at Abcam
Cloud-Clone Corp. Antibodies for METTL23
Search ThermoFisher Antibodies for METTL23
Search LSBio for Antibodies for METTL23

METTL23 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for METTL23
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GenScript Custom Assay Services for METTL23
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for METTL23
Cloud-Clone Corp. CLIAs for METTL23


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR019410 Nicotinamide_N-MeTfrase-like

Graphical View of Domain Structure for InterPro Entry Q86XA0

ProtoNet protein and cluster: Q86XA0

UniProtKB/Swiss-Prot: MET23_HUMAN, Q86XA0
Similarity: Belongs to the methyltransferase superfamily. METTL23 family


METTL23 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: MET23_HUMAN, Q86XA0
Function: Probable methyltransferase (By similarity)

     Enzyme Number (IUBMB): EC 2.1.1.-1

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008168methyltransferase activity IEA--
     
METTL23 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for METTL23
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for METTL23

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL23
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL23

miRNA
Products:
    
miRTarBase miRNAs that target METTL23:
hsa-mir-671-5p (MIRT039287), hsa-mir-99a-5p (MIRT048607)

Block miRNA regulation of human, mouse, rat METTL23 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate METTL23:
hsa-miR-590-3p
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for METTL23
Predesigned siRNA for gene silencing in human, mouse, rat METTL23

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for METTL23

Clone
Products:
     
OriGene clones in human, mouse for METTL23 (see all 6)
OriGene ORF clones in mouse, rat for METTL23
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: METTL23 (NM_001080510)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL23
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat METTL23

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for METTL23
Browse ESI BIO Cell Lines and PureStem Progenitors for METTL23 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL23


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
MET23_HUMAN, Q86XA0: Cytoplasm. Membrane; Single-pass membrane protein (Potential). Note=When overexpressed,
detected in cytoplasmic membrane-like structures

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005737cytoplasm IEA--
GO:0016021integral component of membrane IEA--

METTL23 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL23
Interactions:

    Search GeneGlobe Interaction Network for METTL23

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

Selected Interacting proteins for METTL23 (Q86XA02, 3 ENSP000003415434) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
InteractantInteraction Details
GeneCardExternal ID(s)
BCL2L1Q078172, 3MINT-8249278 I2D: score=2 
TK1P041832, 3MINT-8273015 I2D: score=2 
MUS81ENSP000003078534STRING: ENSP00000307853
TMA16ENSP000003513804STRING: ENSP00000351380
FARS2ENSP000002746804STRING: ENSP00000274680
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for METTL23 (MET23)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for METTL23 gene (6 alternative transcripts): 
NM_001080510.3  NM_001206983.1  NM_001206984.1  NM_001206985.1  NM_001206986.1  NM_001206987.1  

Unigene Cluster for METTL23:

Methyltransferase like 23
Hs.74655  [show with all ESTs]
Unigene Representative Sequence: BM915760
14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000589977 ENST00000591571 ENST00000592849 ENST00000586738 ENST00000588783
ENST00000588563 ENST00000586752 ENST00000588302 ENST00000590964 ENST00000341249(uc021udk.1 uc002jsr.3 uc021udl.1 uc021udm.1 uc002jst.3 uc021udn.1 uc002jsu.3)
ENST00000588822 ENST00000586200 ENST00000589581 ENST00000588964
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat METTL23 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate METTL23:
hsa-miR-590-3p
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for METTL23
Predesigned siRNA for gene silencing in human, mouse, rat METTL23
Clone
Products:
     
OriGene clones in human, mouse for METTL23 (see all 6)
OriGene ORF clones in mouse, rat for METTL23
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: METTL23 (NM_001080510)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL23
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat METTL23
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for METTL23
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL23
  QuantiTect SYBR Green Assays in human, mouse, rat METTL23
  QuantiFast Probe-based Assays in human, mouse, rat METTL23

Additional mRNA sequence: 

BC033998.2 BC045819.1 BC106939.2 JQ313903.1 NR_038193.1 

22 DOTS entries:

DT.97845886  DT.91890924  DT.120924856  DT.451816  DT.120925048  DT.100818660  DT.91750300  DT.100818661 
DT.100818666  DT.117441  DT.100818653  DT.120924815  DT.100818655  DT.100818658  DT.100818665  DT.120925059 
DT.91750309  DT.95125250  DT.100818663  DT.120924831  DT.120924811  DT.92463582 

Selected AceView cDNA sequences (see all 181):

CB151749 CR602837 AA446970 AW272447 AI698701 AA862641 AA767908 AW248931 
CD366688 AI278122 BQ574336 BM762619 AI243833 AI561039 AI926677 AA970390 
AI559530 H80068 BU162021 BI829268 AI078767 BM975884 CA412097 AI922631 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for METTL23 (see all 13)    About this scheme

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e ·
SP1:                                -     -     -     -     -     -     -           -     -                                   -                                 
SP2:                                                        -     -     -                 -                                   -                                 
SP3:                                                              -     -                 -                                   -                                 
SP4:                                -     -     -     -     -     -     -                 -                                                                     
SP5:                                                        -     -     -     -     -     -                                   -                                 

ExUns: 6f · 6g · 6h
SP1:                  
SP2:                  
SP3:                  
SP4:                  
SP5:                  


ECgene alternative splicing isoforms for METTL23

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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METTL23 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGGTCATATA
METTL23 Expression
About this image

METTL23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

METTL23 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.74655
    Custom PCR Arrays for METTL23
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for METTL23
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL23
QuantiTect SYBR Green Assays in human, mouse, rat METTL23
QuantiFast Probe-based Assays in human, mouse, rat METTL23
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL23

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for METTL23 gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Mettl231 , 5 RIKEN cDNA 1110005A03 gene5
methyltransferase like 231
85.96(n)1
89.47(a)1
  11 (81.49 cM)5
743191  NM_028865.31  NP_083141.31 
 1168432785 
chicken
(Gallus gallus)
Aves METTL231 methyltransferase like 23 71.84(n)
71.12(a)
  100859394  XM_003642337.2  XP_003642385.1 
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
51(a)
1 → many
2(111637172-111644030)
tropical clawed frog
(Xenopus tropicalis)
Amphibia mettl231 methyltransferase like 23 66.84(n)
66.67(a)
  100496624  XM_002935924.2  XP_002935970.1 
zebrafish
(Danio rerio)
Actinopterygii si:ch73-366l1.21 si:ch73-366l1.2 63.64(n)
62.57(a)
  337849  XM_003198198.2  XP_003198246.1 
fruit fly
(Drosophila melanogaster)
Insecta CG50131 CG5013 55.37(n)
49.44(a)
  41951  NM_142263.4  NP_650520.1 
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G638551 AT1G63855 53.39(n)
47.66(a)
  842689  NM_202356.1  NP_974085.1 
rice
(Oryza sativa)
Liliopsida Os02g01203001 Os02g0120300 54.03(n)
41.18(a)
  4328111  NM_001052243.1  NP_001045708.1 


ENSEMBL Gene Tree for METTL23 (if available)
TreeFam Gene Tree for METTL23 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for METTL23 gene
ENSG000002671682  
1 SIMAP similar gene for METTL23 using alignment to 10 protein entries:     MET23_HUMAN (see all proteins):
C17orf95

METTL23 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for METTL23 (see all 134)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 17 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1488197381,2
--74724914(+) TCTGTC/TGCCCA 7 -- int10--------
rs65019211,2
C,F,H--74725171(+) ccaccG/Acgccc 7 -- int115Minor allele frequency- A:0.06EA NS NA WA CSA 1030
rs80696391,2
C,F,A,H--74725196(+) gaaacA/Gtagtc 7 -- int18Minor allele frequency- G:0.46NA EA 254
rs80696571,2
C,H--74725237(+) gcgcaA/Gtctcg 7 -- int18Minor allele frequency- G:0.00NA WA CSA 17
rs1931818301,2
--74725452(+) GTCACC/TGTGCC 7 -- int10--------
rs1410770001,2
--74725492(+) TTGCTC/TGTTGC 7 -- int10--------
rs1833589101,2
--74725498(+) GTTGCC/TTCTCT 7 -- int10--------
rs1448911441,2
--74725670(+) GCTGCC/GATTTT 7 -- int10--------
rs3692387061,2
C--74725788(+) CCAGTA/GTGGAA 7 -- ut51 int10--------
rs2022054101,2
C--74725796(+) GAATGT/CATGTT 10 /H /Y mis1 int11Minor allele frequency- C:0.00EU 593

HapMap Linkage Disequilibrium report for METTL23 (74722912 - 74730018 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for METTL23:    About this table    
Variant IDTypeSubtypePubMed ID
nsv833550CNV Loss17160897
nsv908833CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing METTL23
DNA2.0 Custom Variant and Variant Library Synthesis for METTL23

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 615262    OMIM disorders: --

1 disease for METTL23:    
About MalaCards
malaria


METTL23 for disorders           About GeneDecksing


Export disorders for METTL23 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for METTL23 gene integrated from 10 sources:
(articles sorted by number of sources associating them with METTL23)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1, 2 Cloutier P.... Coulombe B. (PLoS Genet. 2013)
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  3. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  5. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
  6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  7. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
  8. (PubMed id )2 

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 124512 HGNC: 26988 AceView: LOC124512 Ensembl:ENSG00000181038 euGenes: HUgn124512
ECgene: METTL23 H-InvDB: METTL23

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for METTL23 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for METTL23 gene:
Search GeneIP for patents involving METTL23

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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