Free for academic non-profit institutions. Other users need a Commercial license

Aliases for METTL21EP Gene

Aliases for METTL21EP Gene

  • Methyltransferase Like 21E, Pseudogene 2 3
  • Methyltransferase Like 21C Pseudogene 1 2 3
  • METTL21CP1 3 4
  • EC 2.1.1.- 4

External Ids for METTL21EP Gene

Previous HGNC Symbols for METTL21EP Gene

  • METTL21CP1

Previous GeneCards Identifiers for METTL21EP Gene

  • GC13P103535

Summaries for METTL21EP Gene

GeneCards Summary for METTL21EP Gene

METTL21EP (Methyltransferase Like 21E, Pseudogene) is a Pseudogene. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot for METTL21EP Gene

  • Protein-lysine methyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for METTL21EP Gene

Genomics for METTL21EP Gene

Genomic Location for METTL21EP Gene

Start:
102,880,099 bp from pter
End:
102,896,033 bp from pter
Size:
15,935 bases
Orientation:
Plus strand

Genomic View for METTL21EP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for METTL21EP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for METTL21EP Gene

No data available for Regulatory Elements for METTL21EP Gene

Proteins for METTL21EP Gene

  • Protein details for METTL21EP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NDL7-MT21E_HUMAN
    Recommended name:
    Putative methyltransferase-like protein 21E pseudogene
    Protein Accession:
    A6NDL7
    Secondary Accessions:

    Protein attributes for METTL21EP Gene

    Size:
    271 amino acids
    Molecular mass:
    31188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for METTL21EP Gene

Proteomics data for METTL21EP Gene at MOPED

Post-translational modifications for METTL21EP Gene

No Post-translational modifications

No data available for DME Specific Peptides for METTL21EP Gene

Domains for METTL21EP Gene

Protein Domains for METTL21EP Gene

Graphical View of Domain Structure for InterPro Entry

A6NDL7

UniProtKB/Swiss-Prot:

MT21E_HUMAN :
  • A6NDL7
Family:
  • Belongs to the methyltransferase superfamily. METTL21 family.
genes like me logo Genes that share domains with METTL21EP: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for METTL21EP Gene

Function for METTL21EP Gene

Molecular function for METTL21EP Gene

UniProtKB/Swiss-Prot Function: Protein-lysine methyltransferase.

Enzyme Numbers (IUBMB) for METTL21EP Gene

Gene Ontology (GO) - Molecular Function for METTL21EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with METTL21EP: view

Animal Model Products

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate METTL21EP
    • Block miRNA regulation of METTL21EP using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for METTL21EP

    In Situ Assay Products

    Flow Cytometry Products

    No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for METTL21EP Gene

    Localization for METTL21EP Gene

    No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for METTL21EP Gene

    Pathways for METTL21EP Gene

    SuperPathways for METTL21EP Gene

    No Data Available

    Interacting Proteins for METTL21EP Gene

    Gene Ontology (GO) - Biological Process for METTL21EP Gene

    GO ID Qualified GO term Evidence PubMed IDs
    GO:0032259 methylation IEA --
    genes like me logo Genes that share ontologies with METTL21EP: view

    No data available for Pathways by source for METTL21EP Gene

    Transcripts for METTL21EP Gene

    mRNA/cDNA for METTL21EP Gene

    (2) Additional mRNA sequences :
    (3) Selected AceView cDNA sequences:
    (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

    Unigene Clusters for METTL21EP Gene

    Methyltransferase like 21E, pseudogene:
    Representative Sequences:

    miRNA Products

    • QIAGEN qRT-PCR Assays for microRNAs that regulate METTL21EP
      • Block miRNA regulation of METTL21EP using miScript Target Protectors

      Inhibitory RNA Products

      • Predesigned siRNA for gene silencing in human,mouse,rat for METTL21EP

      Primer Products

      • QuantiTect SYBR Green Assays in human,mouse,rat
      • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
      • QuantiFast Probe-based Assays in human,mouse,rat

      Flow Cytometry Products

      Alternative Splicing Database (ASD) splice patterns (SP) for METTL21EP Gene

      No ASD Table

      Relevant External Links for METTL21EP Gene

      GeneLoc Exon Structure for
      METTL21EP
      ECgene alternative splicing isoforms for
      METTL21EP

      Expression for METTL21EP Gene

      mRNA expression in normal human tissues for METTL21EP Gene

      mRNA differential expression in normal tissues according to GTEx for METTL21EP Gene

      This gene is overexpressed in Muscle - Skeletal (6.8) and Heart - Left Ventricle (5.9).

      Integrated Proteomics: protein expression from ProteomicsDB and MOPED for METTL21EP Gene

      SOURCE GeneReport for Unigene cluster for METTL21EP Gene Hs.660773

      genes like me logo Genes that share expressions with METTL21EP: view

      In Situ Assay Products

      No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for METTL21EP Gene

      Orthologs for METTL21EP Gene

      This gene was present in the common ancestor of human and mouse.

      Orthologs for METTL21EP Gene

      Organism Taxonomy Gene Similarity Type Details
      mouse
      (Mus musculus)
      Mammalia Mettl21e 16
      Species with no ortholog for METTL21EP:
      • A. gosspyii yeast (Ashbya gossypii)
      • Actinobacteria (Mycobacterium tuberculosis)
      • African clawed frog (Xenopus laevis)
      • African malaria mosquito (Anopheles gambiae)
      • Alicante grape (Vitis vinifera)
      • alpha proteobacteria (Wolbachia pipientis)
      • amoeba (Dictyostelium discoideum)
      • Archea (Pyrococcus horikoshii)
      • baker's yeast (Saccharomyces cerevisiae)
      • barley (Hordeum vulgare)
      • beta proteobacteria (Neisseria meningitidis)
      • bread mold (Neurospora crassa)
      • chicken (Gallus gallus)
      • chimpanzee (Pan troglodytes)
      • Chromalveolata (Phytophthora infestans)
      • common water flea (Daphnia pulex)
      • corn (Zea mays)
      • cow (Bos Taurus)
      • dog (Canis familiaris)
      • E. coli (Escherichia coli)
      • filamentous fungi (Aspergillus nidulans)
      • Firmicute bacteria (Streptococcus pneumoniae)
      • fission yeast (Schizosaccharomyces pombe)
      • fruit fly (Drosophila melanogaster)
      • green algae (Chlamydomonas reinhardtii)
      • honey bee (Apis mellifera)
      • K. lactis yeast (Kluyveromyces lactis)
      • lizard (Anolis carolinensis)
      • loblloly pine (Pinus taeda)
      • malaria parasite (Plasmodium falciparum)
      • medicago trunc (Medicago Truncatula)
      • moss (Physcomitrella patens)
      • oppossum (Monodelphis domestica)
      • orangutan (Pongo pygmaeus)
      • pig (Sus scrofa)
      • platypus (Ornithorhynchus anatinus)
      • rainbow trout (Oncorhynchus mykiss)
      • rat (Rattus norvegicus)
      • rice (Oryza sativa)
      • rice blast fungus (Magnaporthe grisea)
      • schistosome parasite (Schistosoma mansoni)
      • sea anemone (Nematostella vectensis)
      • sea squirt (Ciona intestinalis)
      • sea squirt (Ciona savignyi)
      • sea urchin (Strongylocentrotus purpuratus)
      • sorghum (Sorghum bicolor)
      • soybean (Glycine max)
      • stem rust fungus (Puccinia graminis)
      • sugarcane (Saccharum officinarum)
      • thale cress (Arabidopsis thaliana)
      • tomato (Lycopersicon esculentum)
      • toxoplasmosis (Toxoplasma gondii)
      • Trichoplax (Trichoplax adhaerens)
      • tropical clawed frog (Silurana tropicalis)
      • wheat (Triticum aestivum)
      • worm (Caenorhabditis elegans)
      • zebrafish (Danio rerio)

      Evolution for METTL21EP Gene

      ENSEMBL:
      Gene Tree for METTL21EP (if available)
      TreeFam:
      Gene Tree for METTL21EP (if available)

      Paralogs for METTL21EP Gene

      Selected SIMAP similar genes for METTL21EP Gene using alignment to 1 proteins:

      genes like me logo Genes that share paralogs with METTL21EP: view

      No data available for Paralogs for METTL21EP Gene

      Variants for METTL21EP Gene

      Sequence variations from dbSNP and Humsavar for METTL21EP Gene

      SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
      rs751057 -- 102,878,291(+) CTGTA(C/T)CTTCC upstream-variant-2KB
      rs752344 -- 102,879,848(-) AGTTA(C/T)TCTAA upstream-variant-2KB
      rs943248 -- 102,879,317(-) GGGAG(A/G)CCAAG upstream-variant-2KB
      rs1886087 -- 102,883,478(-) GAGAA(A/T)ATCAG intron-variant
      rs2146987 -- 102,895,462(+) GCGGA(C/T)GTGGT nc-transcript-variant

      Relevant External Links for METTL21EP Gene

      HapMap Linkage Disequilibrium report
      METTL21EP

      No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for METTL21EP Gene

      Disorders for METTL21EP Gene

      No disorders were found for METTL21EP Gene.

      No data available for UniProtKB/Swiss-Prot for METTL21EP Gene

      Publications for METTL21EP Gene

      1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
      2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3
      3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4

      Products for METTL21EP Gene

      • QIAGEN qRT-PCR Assays for microRNAs that regulate METTL21EP
        • QuantiTect SYBR Green Assays in human,mouse,rat
        • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
        • QuantiFast Probe-based Assays in human,mouse,rat
        • Predesigned siRNA for gene silencing in human,mouse,rat for METTL21EP
        • Block miRNA regulation of METTL21EP using miScript Target Protectors

        Sources for METTL21EP Gene

        Back to Top

        Content