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Aliases for METTL21EP Gene

Aliases for METTL21EP Gene

  • Methyltransferase Like 21E, Pseudogene 2 3
  • Methyltransferase Like 21C Pseudogene 1 2 3
  • METTL21CP1 3 4
  • EC 2.1.1.- 4

External Ids for METTL21EP Gene

Previous Symbols for METTL21EP Gene

  • METTL21CP1

Summaries for METTL21EP Gene

GeneCards Summary for METTL21EP Gene

METTL21EP (Methyltransferase Like 21E, Pseudogene) is a Pseudogene. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot for METTL21EP Gene

  • Protein-lysine methyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for METTL21EP Gene

Genomics for METTL21EP Gene

Genomic Location for METTL21EP Gene

Start:
102,880,099 bp from pter
End:
102,896,033 bp from pter
Size:
15,935 bases
Orientation:
Plus strand

Genomic View for METTL21EP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for METTL21EP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for METTL21EP Gene

No data available for Regulatory Elements for METTL21EP Gene

Proteins for METTL21EP Gene

  • Protein details for METTL21EP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NDL7-MT21E_HUMAN
    Recommended name:
    Putative methyltransferase-like protein 21E pseudogene
    Protein Accession:
    A6NDL7
    Secondary Accessions:

    Protein attributes for METTL21EP Gene

    Size:
    271 amino acids
    Molecular mass:
    31188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for METTL21EP Gene

Proteomics data for METTL21EP Gene at MOPED

Post-translational modifications for METTL21EP Gene

No Post-translational modifications

No data available for DME Specific Peptides for METTL21EP Gene

Domains for METTL21EP Gene

Protein Domains for METTL21EP Gene

UniProtKB/Swiss-Prot:

MT21E_HUMAN
Family:
  • Belongs to the methyltransferase superfamily. METTL21 family.:
    • A6NDL7
genes like me logo Genes that share domains with METTL21EP: view

No data available for Gene Families for METTL21EP Gene

Function for METTL21EP Gene

Molecular function for METTL21EP Gene

UniProtKB/Swiss-Prot Function: Protein-lysine methyltransferase.

Enzyme Numbers (IUBMB) for METTL21EP Gene

Gene Ontology (GO) - Molecular Function for METTL21EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with METTL21EP: view

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for METTL21EP Gene

Localization for METTL21EP Gene

No data available for Gene Ontology (GO) - Cellular Components for METTL21EP Gene

Pathways for METTL21EP Gene

SuperPathways for METTL21EP Gene

No Data Available

Interacting Proteins for METTL21EP Gene

Gene Ontology (GO) - Biological Process for METTL21EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with METTL21EP: view

No data available for Pathways by source for METTL21EP Gene

Transcripts for METTL21EP Gene

mRNA/cDNA for METTL21EP Gene

(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for METTL21EP Gene

Methyltransferase like 21E, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for METTL21EP Gene

No ASD Table

Relevant External Links for METTL21EP Gene

GeneLoc Exon Structure for
METTL21EP
ECgene alternative splicing isoforms for
METTL21EP

Expression for METTL21EP Gene

mRNA expression in normal human tissues for METTL21EP Gene

mRNA differential expression in normal tissues according to GTEx for METTL21EP Gene

This gene is overexpressed in Muscle - Skeletal (6.8) and Heart - Left Ventricle (5.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for METTL21EP Gene

SOURCE GeneReport for Unigene cluster for METTL21EP Gene Hs.660773

genes like me logo Genes that share expressions with METTL21EP: view

Orthologs for METTL21EP Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for METTL21EP Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Mettl21e 16
Species with no ortholog for METTL21EP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for METTL21EP Gene

ENSEMBL:
Gene Tree for METTL21EP (if available)
TreeFam:
Gene Tree for METTL21EP (if available)

Paralogs for METTL21EP Gene

Selected SIMAP similar genes for METTL21EP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with METTL21EP: view

No data available for Paralogs for METTL21EP Gene

Variants for METTL21EP Gene

Sequence variations from dbSNP and Humsavar for METTL21EP Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs751057 -- 102,878,291(+) CTGTA(C/T)CTTCC upstream-variant-2KB
rs752344 -- 102,879,848(-) AGTTA(C/T)TCTAA upstream-variant-2KB
rs943248 -- 102,879,317(-) GGGAG(A/G)CCAAG upstream-variant-2KB
rs1886087 -- 102,883,478(-) GAGAA(A/T)ATCAG intron-variant
rs2146987 -- 102,895,462(+) GCGGA(C/T)GTGGT nc-transcript-variant

Relevant External Links for METTL21EP Gene

HapMap Linkage Disequilibrium report
METTL21EP

No data available for Structural Variations from Database of Genomic Variants (DGV) for METTL21EP Gene

Disorders for METTL21EP Gene

No disorders were found for METTL21EP Gene.

No data available for UniProtKB/Swiss-Prot for METTL21EP Gene

Publications for METTL21EP Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4

Products for METTL21EP Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate METTL21EP
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for METTL21EP
    • Block miRNA regulation of METTL21EP using miScript Target Protectors

    Sources for METTL21EP Gene

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