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METTL21B Gene

protein-coding   GIFtS: 42
GCID: GC12P058165

Methyltransferase Like 21B

(Previous names: family with sequence similarity 119, member B)
(Previous symbol: FAM119B)
  See METTL21B-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Methyltransferase Like 21B1 2     Hepatocellularcarcinoma-Associated Antigen HCA557a2
FAM119B1 2 3 5     Protein-Lysine Methyltransferase METTL21B2
Family With Sequence Similarity 119, Member B1 2     EC 2.1.1.-3
Hepatocellular Carcinoma-Associated Antigen 557a2 3     HCA557A3
Methyltransferase-Like Protein 21B2 3     

External Ids:    HGNC: 249361   Entrez Gene: 258952   Ensembl: ENSG000001234277   OMIM: 6152585   UniProtKB: Q96AZ13   

Export aliases for METTL21B gene to outside databases

Previous GC identifer: GC12P058168


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL21B Gene:
METTL21B (methyltransferase like 21B) is a protein-coding gene. Diseases associated with METTL21B include hepatocellular carcinoma. GO annotations related to this gene include methyltransferase activity. An important paralog of this gene is METTL21C.

UniProtKB/Swiss-Prot: MT21B_HUMAN, Q96AZ1
Function: Protein-lysine methyltransferase (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for METTL21B
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): METTL21B promoter sequence
   Search Chromatin IP Primers for METTL21B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL21B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q14.1   Ensembl cytogenetic band:  12q14.1   HGNC cytogenetic band: 12q14.1

METTL21B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL21B gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P058165:  view genomic region     (about GC identifiers)

Start:
58,165,275 bp from pter      End:
58,176,324 bp from pter
Size:
11,050 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MT21B_HUMAN, Q96AZ1 (See protein sequence)
Recommended Name: Protein-lysine methyltransferase METTL21B  
Size: 226 amino acids; 24911 Da
Subunit: Interacts with members of the heat shock protein 70 and 90 families and of the TCP-1 chaperonin family,
as well as with HSPD1, STIP1 and tubulin; at least some of these proteins may be methylation substrates
(PubMed:23349634)
Secondary accessions: Q9H749 Q9Y3W2
Alternative splicing: 3 isoforms:  Q96AZ1-1   Q96AZ1-2   Q96AZ1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for METTL21B: NX_Q96AZ1

Explore proteomics data for METTL21B at MOPED


See METTL21B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_056248.2  NP_996797.1  

ENSEMBL proteins: 
 ENSP00000447718   ENSP00000448163   ENSP00000300209   ENSP00000327425  

METTL21B Human Recombinant Protein Products:

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Novus Biologicals METTL21B Protein
Novus Biologicals METTL21B Lysates
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Cloud-Clone Corp. Proteins for METTL21B

 
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antibodies-online proteins for METTL21B (4 products) 

 
Search antibodies-online for peptides for METTL21B

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antibodies-online antibodies for METTL21B (2 products) 

METTL21B Assay Products:

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antibodies-online kits for METTL21B (3 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR019410 Nicotinamide_N-MeTfrase-like

Graphical View of Domain Structure for InterPro Entry Q96AZ1

ProtoNet protein and cluster: Q96AZ1

UniProtKB/Swiss-Prot: MT21B_HUMAN, Q96AZ1
Similarity: Belongs to the methyltransferase superfamily. METTL21 family


Find genes that share domains with METTL21B           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: MT21B_HUMAN, Q96AZ1
Function: Protein-lysine methyltransferase (By similarity)

     Enzyme Number (IUBMB): EC 2.1.1.-1

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008168methyltransferase activity IEA--
     
Find genes that share ontologies with METTL21B           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for METTL21B:
 Increased G1 DNA content 

Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for METTL21B

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat METTL21B using miScript Target Protectors
6 qRT-PCR Assays for microRNAs that regulate METTL21B:
hsa-miR-4251 hsa-miR-133a hsa-miR-4323 hsa-miR-133b hsa-miR-548c-3p hsa-miR-4257
SwitchGear 3'UTR luciferase reporter plasmidMETTL21B 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat METTL21B

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DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL21B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL21B

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL21B


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
MT21B_HUMAN, Q96AZ1: Cytoplasm

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular IDA--
GO:0005737cytoplasm IEA--

Find genes that share ontologies with METTL21B           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL21B
Interactions:

    Search GeneGlobe Interaction Network for METTL21B

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5 Interacting proteins for METTL21B (ENSP000003002094) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
MUS81ENSP000003078534STRING: ENSP00000307853
TMA16ENSP000003513804STRING: ENSP00000351380
ELAVL1ENSP000003852694STRING: ENSP00000385269
FARS2ENSP000002746804STRING: ENSP00000274680
FDXACB1ENSP000002602574STRING: ENSP00000260257
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for METTL21B (MT21B)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for METTL21B gene (2 alternative transcripts): 
NM_015433.2  NM_206914.1  

Unigene Cluster for METTL21B:

Methyltransferase like 21B
Hs.632720  [show with all ESTs]
Unigene Representative Sequence: NM_206914
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000548256 ENST00000551420 ENST00000300209 ENST00000552307 ENST00000333012(uc001sqf.3 uc001sqg.3 uc009zqd.3)

miRNA
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6 qRT-PCR Assays for microRNAs that regulate METTL21B:
hsa-miR-4251 hsa-miR-133a hsa-miR-4323 hsa-miR-133b hsa-miR-548c-3p hsa-miR-4257
SwitchGear 3'UTR luciferase reporter plasmidMETTL21B 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for METTL21B
Predesigned siRNA for gene silencing in human, mouse, rat METTL21B
Clone
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OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): METTL21B (NM_015433)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL21B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL21B
Primer
Products:
    
OriGene qPCR primer pairs and template standards for METTL21B
OriGene qSTAR qPCR primer pairs in human, mouse for METTL21B
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat METTL21B
  QuantiTect SYBR Green Assays in human, mouse, rat METTL21B
  QuantiFast Probe-based Assays in human, mouse, rat METTL21B

Additional mRNA sequence: 

AF455816.1 AK024983.1 AK292276.1 AL050100.1 BC016395.1 BC099841.1 BC103501.1 

7 DOTS entries:

DT.316148  DT.95368030  DT.95187181  DT.100754203  DT.99978072  DT.100829597  DT.75104297 

Selected AceView cDNA sequences (see all 276):

BX117129 AF110399 AW468471 AU143121 BE252419 BU737269 BX386668 BQ923269 
BM048745 AI359125 AL050100 BU618769 BM836337 BE741613 CK823940 AU122778 
CA311578 BM730099 AU119538 AW270975 NM_015433 CR606259 AL556814 BE326609 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for METTL21B    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b
SP1:              -                 -               
SP2:              -           -                     
SP3:                                -               


ECgene alternative splicing isoforms for METTL21B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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METTL21B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
METTL21B Expression
About this image

METTL21B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

METTL21B Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.632720
    Custom PCR Arrays for METTL21B
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QuantiFast Probe-based Assays in human, mouse, rat METTL21B
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL21B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for METTL21B gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Mettl21b5
LOC1005046081
family with sequence similarity 119, member B5
protein FAM119B-like1
86.28(n)1
84.96(a)1
  10 (74.50 cM)5
1005046081  NM_001205036.11  NP_001191965.11 
 1270311825 
chicken
(Gallus gallus)
Aves --
Uncharacterized protein
30(a)
many ↔ many
1(141986530-142004203)
lizard
(Anolis carolinensis)
Reptilia METTL21B6
methyltransferase like 21B
58(a)
1 ↔ 1
2(66950894-66957773)
tropical clawed frog
(Xenopus tropicalis)
Amphibia mettl21b1 methyltransferase like 21B 61.62(n)
60.55(a)
  549414  NM_001016660.2  NP_001016660.1 
zebrafish
(Danio rerio)
Actinopterygii zgc:925186
zgc:92518
34(a)
many ↔ many
1(341477-346622) ENSDARG00000016343
worm
(Caenorhabditis elegans)
Secernentea C42C1.136
Protein C42C1.13, isoform b
32(a)
1 → many
IV(12278767-12279546) WBGene00016591
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes (YBR271W)4 Putative S-adenosylmethionine-dependent methyltransferase more   --   2(744852-746111) 852574  NP_009830.1 


ENSEMBL Gene Tree for METTL21B (if available)
TreeFam Gene Tree for METTL21B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for METTL21B gene
METTL21C2  VCPKMT2  METTL21A2  
2 SIMAP similar genes for METTL21B using alignment to 3 protein entries:     MT21B_HUMAN (see all proteins):
METTL21A    METTL21EP

Find genes that share paralogs with METTL21B           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for METTL21B (see all 137)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1874265761,2
--58167985(+) CTAGCC/TGGGCG 2 -- int10--------
rs108770161,2
C,F,A,H--58167992(+) GGCGCA/GGTGGC 2 -- int115Minor allele frequency- G:0.35NS EA NA 1982
rs1394418931,2
C--58168030(+) AGGCCA/GAGGTG 2 -- int10--------
rs73161091,2
C--58168065(+) ttgagA/Gccagc 2 -- int10--------
rs1127492161,2
F--58168119(+) TTAGCC/TGAGCA 2 -- int11Minor allele frequency- T:0.50CSA 2
rs1487858201,2
--58168187(+) GAACCC/TGGGAG 2 -- int10--------
rs124274121,2
H--58168234(+) ctccaA/Gcctgg 2 -- int10--------
rs1424668021,2
--58168246(+) CAACAA/GGAGTG 2 -- int10--------
rs2002125991,2
C--58168491(+) TGTGGA/TCATGC 3 G int1 syn11Minor allele frequency- T:0.00EU 1269
rs1498836881,2
C--58168493(+) TGGACA/GTGCTC 3 H R int1 mis11Minor allele frequency- G:0.00NA 4544

HapMap Linkage Disequilibrium report for METTL21B (58165275 - 58176324 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for METTL21B:    About this table    
Variant IDTypeSubtypePubMed ID
nsv899121CNV Loss21882294
nsv510601CNV Loss20534489
nsv470296CNV Loss18288195
nsv470297CNV Gain18288195

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing METTL21B
DNA2.0 Custom Variant and Variant Library Synthesis for METTL21B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 615258    OMIM disorders: --

1 disease for METTL21B:    
About MalaCards
hepatocellular carcinoma


Find genes that share disorders with METTL21B           About GenesLikeMe


Export disorders for METTL21B gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for METTL21B gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with METTL21B)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1, 2 Cloutier P.... Coulombe B. (PLoS Genet. 2013)
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  3. The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. (PubMed id 20190274)1 Gandhi K.S....Booth D.R. (Hum. Mol. Genet. 2010)
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
  5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
  6. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  9. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (Genome Res. 2004)
  10. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1 Simpson J.C.... Wiemann S. (EMBO Rep. 2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 25895 HGNC: 24936 AceView: TSFMandDKFZP586D0919 Ensembl:ENSG00000123427 euGenes: HUgn25895
ECgene: METTL21B H-InvDB: METTL21B

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for METTL21B Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for METTL21B gene:
Search GeneIP for patents involving METTL21B

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for METTL21B  
 OriGene qPCR primer pairs and template standards for METTL21B   OriGene Protein Over-expression Lysate for METTL21B  
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 OriGene Custom Antibody Services for METTL21B   OriGene Custom Protein Services for METTL21B  

 
 
 Block miRNA regulation of human, mouse, rat METTL21B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing METTL21B
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL21B Predesigned siRNA for gene silencing in human, mouse, rat METTL21B
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 Custom PCR Arrays for METTL21B Search Chromatin IP Primers for METTL21B
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat METTL21B  Search GeneGlobe Interaction Network for METTL21B
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 GenScript Custom Purified and Recombinant Proteins Services for METTL21B GenScript cDNA clones with any tag delivered in your preferred vector for METTL21B
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 Search Tocris compounds for METTL21B (MT21B)
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 METTL21B antibodies
 METTL21B proteins
 METTL21B lysates
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 See all of Abcam's Antibodies, Kits and Proteins for METTL21B
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for METTL21B
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 Browse ESI BIO Cell Lines and PureStem Progenitors for METTL21B
 Gene Synthesis
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 Variant Library Synthesis
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 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL21B
 SwitchGear 3'UTR luciferase reporter plasmids for METTL21B
 SwitchGear Promoter luciferase reporter plasmids for METTL21B
 Search ThermoFisher Antibodies for METTL21B
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL21B
 Browse compounds at ApexBio
 Search Addgene for plasmids for METTL21B
  Search eBioscience for proteins for METTL21B
  Search eBioscience for elisas for METTL21B
  eBioscience FlowRNA Probe Sets
 genOway: Develop your customized and physiologically relevant rodent model for METTL21B
 antibodies-online antibodies for METTL21B (2 products)
 antibodies-online kits for METTL21B (3 products)
  Search antibodies-online for peptides for METTL21B
 antibodies-online proteins for METTL21B (4 products)
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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