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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

METTL16 Gene

protein-coding GIFtS: 41
GCID: GC17M002319

Methyltransferase Like 16

(Previous name: methyltransferase 10 domain containing)
(Previous symbol: METT10D)

Search for METTL16
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Methyltransferase Like 16¹ ²		Methyltransferase-Like Protein 16²
METT10D¹ ² ³		Putative Methyltransferase METT10D²
Methyltransferase 10 Domain Containing¹ ²		EC 2.1.1.-³
Methyltransferase 10 Domain-Containing Protein² ³

External Ids:	HGNC: 28484¹	Entrez Gene: 79066²	Ensembl: ENSG00000127804⁷	UniProtKB: Q86W50³

Export aliases for METTL16 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for METTL16 Gene:

METTL16 (methyltransferase like 16) is a protein-coding gene. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: MET16_HUMAN, Q86W50

Function: Probable methyltransferase (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NT_010718.16 NC_018928.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for METTL16
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: METTL16 promoter sequence

Search SABiosciences Chromatin IP Primers for METTL16

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat METTL16

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3

METTL16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL16 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M002319: view genomic region (about GC identifiers)

Start:	2,319,343 bp from pter	End:	2,415,200 bp from pter
Size:	95,858 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MET16_HUMAN, Q86W50 (See protein sequence)

Recommended Name: Methyltransferase-like protein 16

Size: 562 amino acids; 63621 Da

Sequence caution: Sequence=BAB55094.1; Type=Erroneous termination; Positions=505; Note=Translated as Lys;

Sequence=CAD89999.2; Type=Frameshift; Positions=424;

1 PDB 3D structure from and Proteopedia for METTL16:

2H00 (3D)

Secondary accessions: D3DTI8 Q86TE5 Q96T16 Q9BVG7

Alternative splicing: 2 isoforms: Q86W50-1 Q86W50-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for METTL16: NX_Q86W50

Explore proteomics data for METTL16 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q86W50

METTL16 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_076991.3

ENSEMBL proteins:

ENSP00000458710 ENSP00000263092 ENSP00000460775 ENSP00000460207 ENSP00000465733

ENSP00000461546 ENSP00000443633

Human Recombinant Protein Products for METTL16:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

2 InterPro protein domains:

IPR010286 rRNA_lsu_MeTfrase_F-like

IPR017182 S-AdoMet-dep_MeTrfase_Mett10D

Graphical View of Domain Structure for InterPro Entry Q86W50

ProtoNet protein and cluster: Q86W50

UniProtKB/Swiss-Prot: MET16_HUMAN, Q86W50

Similarity: Belongs to the methyltransferase superfamily. METTL16/RlmF family

METTL16 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MET16_HUMAN, Q86W50

Function: Probable methyltransferase (By similarity)

Enzyme Number (IUBMB): EC 2.1.1.-¹

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008168	methyltransferase activity	IEA	--

METTL16 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for METTL16

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for METTL16

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL16

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL16

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat METTL16
		8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate METTL16 (see all 19):
		hsa-miR-644 hsa-miR-100* hsa-miR-607 hsa-miR-19b-2* hsa-miR-3692 hsa-miR-10b* hsa-miR-124 hsa-miR-506

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for METTL16
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL16

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for METTL16

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for METTL16 (Q86W50³ ENSP00000263092⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MEPCE	Q7L2J0³, ENSP00000308546⁴	I2D: score=1 STRING: ENSP00000308546
SYVN1	Q86TM6³	I2D: score=4

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for METTL16 (MET16)

Search CenterWatch for drugs/clinical trials and news about METTL16 / MET16

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for METTL16 gene:

NM_024086.3

Unigene Cluster for METTL16:

Methyltransferase like 16

Hs.632237 [show with all ESTs]

Unigene Representative Sequence: NM_024086

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000574623 ENST00000576155(uc002fut.3 uc002fuu.4 uc002fuv.3)

ENST00000571669(uc010cka.3) ENST00000263092(uc010vqx.1 uc010vqy.1)

ENST00000576556 ENST00000574752 ENST00000571298 ENST00000576976 ENST00000577148

ENST00000538844

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat METTL16
		8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate METTL16 (see all 19):
		hsa-miR-644 hsa-miR-100* hsa-miR-607 hsa-miR-19b-2* hsa-miR-3692 hsa-miR-10b* hsa-miR-124 hsa-miR-506

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for METTL16
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat METTL16

Clone Products:		OriGene clones in human, mouse for METTL16 (see all 8) OriGene ORF clones in mouse, rat for METTL16 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Primer Products:		OriGene qPCR primer pairs and template standards for METTL16 OriGene qSTAR qPCR primer pairs in human, mouse for METTL16
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL16
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL16

Additional mRNA sequence:

AK027410.1 AK098286.1 AK294547.1 AK296464.1 AL832612.2 BC001213.1 BC047770.1 BC050603.1

BX647255.1

14 DOTS entries:

DT.100784401 DT.315243 DT.95250220 DT.101982043 DT.120948776 DT.120948777 DT.100023147 DT.99948339

DT.91697169 DT.91711600 DT.100035865 DT.120948768 DT.92419553 DT.120948699

24/198 AceView cDNA sequences (see all 198):

BC050603 AI684986 AA931537 BX281910 AW303538 BM981103 BM838546 F00469

BU195372 BM669313 BX281827 Z39510 BE348790 AI791528 AI298404 AI733038

BF924710 BM456665 D31132 AA505863 AA527563 BX105079 CB215532 F04092

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

METTL16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

See METTL16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for METTL16

SOURCE GeneReport for Unigene cluster: Hs.632237

SABiosciences Custom PCR Arrays for METTL16

Primer Products:		OriGene qPCR primer pairs and template standards for METTL16 OriGene qSTAR qPCR primer pairs in human, mouse for METTL16
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat METTL16
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL16
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL16

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL16

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for METTL16 gene from 7/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mettl16^{1 , 5}	methyltransferase like 16^{1, 5}	86.47(n)¹ 89.49(a)¹		11 (45.76 cM)⁵ 67493¹ NM_026197.3¹ NP_080473.1¹ 74770830⁵
chicken (Gallus gallus)	Aves	METTL16¹	methyltransferase like 16	70.8(n) 77.02(a)		431184 NM_001031602.1 NP_001026773.1
lizard (Anolis carolinensis)	Reptilia	METTL16⁶	Uncharacterized protein	71(a)	1 ↔ 1	6(66088934-66115751)
African clawed frog (Xenopus laevis)	Amphibia	Xl.7647²	Xenopus laevis transcribed sequence with moderate similarity to protein refNP_076991.1 (H.sapiens) hypothetical protein MGC3329 [Homo sapiens] less	79(n)		BU913728.1
zebrafish (Danio rerio)	Actinopterygii	mettl16¹	methyltransferase like 16	70.52(n) 77.56(a)		445217 NM_001003611.1 NP_001003611.1
fruit fly (Drosophila melanogaster)	Insecta	CG7544¹	CG7544	51.18(n) 45.39(a)		36680 NM_001169685.1 NP_001163156.1
worm (Caenorhabditis elegans)	Secernentea	mett-10¹	Protein METT-10	48.75(n) 42.64(a)		191526 NM_066846.3 NP_499247.2

ENSEMBL Gene Tree for METTL16 (if available)
TreeFam Gene Tree for METTL16 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11868221^1,2	H	--	2320798(+)	`ATTCTC/TTGGAA`	1	--	ut3¹		4		NS EA	418
rs192036644^1,2		--	2320808(+)	`AATCCC/TTACGA`	1	--	ut3¹		0	--	--	--	--
rs75810416^1,2	C,F	--	2320839(+)	`CTGTGC/TCTGAA`	1	--	ut3¹		1		WA	118
rs145555412^1,2		--	2320857(+)	`TTGAAC/TAGGCA`	1	--	ut3¹		0	--	--	--	--
rs148911190^1,2		--	2321027(+)	`AACACA/GCCAAT`	1	--	ut3¹		0	--	--	--	--
rs76292112^1,2	C	--	2321106(+)	`CAAATC/TTTTAA`	1	--	ut3¹		0	--	--	--	--
rs181669474^1,2		--	2321176(+)	`GAATGA/TATAGT`	1	--	ut3¹		0	--	--	--	--
rs186521395^1,2		--	2321224(+)	`AACTAC/GGTTTG`	1	--	ut3¹		0	--	--	--	--
rs5015342^1,2	C,F,A,H	--	2321253(+)	`AATGTA/GATATT`	1	--	ut3¹		31		NS EA NA WA CSA	2922
rs190915768^1,2		--	2321392(+)	`ACATGA/TATGCT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for METTL16 (2319343 - 2415200 bp)

Structural Variations
Database of Genomic Variants (DGV) 9 variations for METTL16: About this table

Variant ID	Type	Subtype	PubMed ID
esv2669015	CNV	Deletion	23128226
esv2675053	CNV	Deletion	23128226
nsv907532	CNV	Loss	21882294
nsv819217	CNV	Loss	19587683
esv22012	CNV	Loss	19812545
nsv833338	CNV	Loss	17160897
nsv111844	CNV	Loss	16902084
nsv907538	CNV	Loss	21882294
nsv907539	CNV	Gain	21882294

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing METTL16

DNA2.0 Custom Variant and Variant Library Synthesis for METTL16

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for METTL16 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with METTL16)

Utopia: connect your pdf to the dynamic
world of online information

The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel. (PubMed id 18021804)^{1, 3} Sergiev P.V....Dontsova O.A. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Generalist genes analysis of DNA markers associated w ith mathematical ability and disability reveals shared influence across ages an d abilities. (PubMed id 20602751)¹ Docherty S.J....Plomin R. (2010)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)² Daub H.... Mann M. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)¹ Jeronimo C.... Coulombe B. (2007)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 79066	HGNC: 28484	AceView: MGC3329	Ensembl:ENSG00000127804	euGenes: HUgn79066
ECgene: METTL16	H-InvDB: METTL16

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for METTL16	Pharmacogenomics, SNPs, Pathways

Intellectual Property for METTL16 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for METTL16 gene:
Search GeneIP for patents involving METTL16

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


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	OriGene Antibodies for METTL16		OriGene RNAi products in human, mouse, rat for METTL16
	OriGene qPCR primer pairs and template standards for METTL16		OriGene Protein Over-expression Lysate for METTL16
	OriGene MassSpec something-or-other for METTL16		OriGene clones in human, mouse for METTL16
	OriGene qSTAR qPCR primer pairs in human, mouse for METTL16		OriGene Purified Protein for METTL16
	OriGene ORF clones in mouse, rat for METTL16		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for METTL16		OriGene Custom Protein Services for METTL16

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat METTL16
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing METTL16
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat METTL16
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat METTL16
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL16
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL16

	GenScript Custom Purified and Recombinant Proteins Services for METTL16		GenScript cDNA clones with any tag delivered in your preferred vector for METTL16
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	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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ThermoFisher Antibodies for METTL16

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL16

	inGenious Targeting Laboratory - Custom generated mouse model solutions for METTL16
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for METTL16

Customized:

	lentivirus for stable overexpression of METTL16
	lentivirus expression plasmids for stable overexpression of METTL16
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LSBio Antibodies in human, mouse, rat for METTL16

Customized transgenic rodents for:

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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes METTL16 gene at Home site.

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METTL16 Gene

Methyltransferase Like 16

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for METTL16 gene

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Export list of displayed genes

METTL16 Gene

Methyltransferase Like 16

Aliasesfor METTL16 gene

Summariesfor METTL16 gene

Genomic Viewsfor METTL16 gene

Proteinsfor METTL16 gene

Protein Domains /Familiesfor METTL16 gene

Functionfor METTL16 gene

Pathways & Interactionsfor METTL16 gene

Drugs & Compoundsfor METTL16 gene

Transcriptsfor METTL16 gene

Expression for METTL16 gene

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for METTL16 gene

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for METTL16 gene

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for METTL16 gene

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for METTL16 gene

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Families
for METTL16 gene

Function
for METTL16 gene

Pathways & Interactions
for METTL16 gene

Drugs & Compounds
for METTL16 gene

Transcripts
for METTL16 gene

Expression
for METTL16 gene

Orthologs
for METTL16 gene

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for METTL16 gene

Genomic Variants
for METTL16 gene

Disorders / Diseases
for METTL16 gene

Publications
for METTL16 gene

Intellectual Property
for METTL16 gene

Products
for METTL16 gene