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METTL16 Gene

protein-coding   GIFtS: 42
GCID: GC17M002316

Methyltransferase Like 16

(Previous name: methyltransferase 10 domain containing)
(Previous symbol: METT10D)
  See related disease
at
MalaCards
 

Aliases
for METTL16 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Methyltransferase Like 161 2     Methyltransferase-Like Protein 162
METT10D1 2 3     Putative Methyltransferase METT10D2
Methyltransferase 10 Domain Containing1 2     EC 2.1.1.-3
Methyltransferase 10 Domain-Containing Protein2 3     

External Ids:    HGNC: 284841   Entrez Gene: 790662   Ensembl: ENSG000001278047   UniProtKB: Q86W503   
ORGUL members:         

Export aliases for METTL16 gene to outside databases

Previous GC identifer: GC17M002319


Summaries
for METTL16 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL16 Gene:
METTL16 (methyltransferase like 16) is a protein-coding gene. Diseases associated with METTL16 include malaria. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: MET16_HUMAN, Q86W50
Function: Probable methyltransferase (By similarity)




Genomic Views
for METTL16 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010718.17  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for METTL16
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: METTL16 promoter sequence
   Search Chromatin IP Primers for METTL16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.3   HGNC cytogenetic band: 17p13.3

METTL16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL16 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M002316:  view genomic region     (about GC identifiers)

Start:
 2,308,856 bp from pter      End:
 2,415,200 bp from pter
Size:
 106,345 bases      Orientation:
 minus strand

Proteins
for METTL16 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MET16_HUMAN, Q86W50 (See protein sequence)
Recommended Name: Methyltransferase-like protein 16  
Size: 562 amino acids; 63621 Da
Sequence caution: Sequence=BAB55094.1; Type=Erroneous termination; Positions=505; Note=Translated as Lys;
Sequence=CAD89999.2; Type=Frameshift; Positions=424;
1 PDB 3D structure from and Proteopedia for METTL16:
2H00 (3D)    
Secondary accessions: D3DTI8 Q86TE5 Q96T16 Q9BVG7
Alternative splicing: 2 isoforms:  Q86W50-1   Q86W50-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for METTL16: NX_Q86W50

Explore proteomics data for METTL16 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See METTL16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_076991.3  
    ENSEMBL proteins: 
     ENSP00000263092   ENSP00000460775   ENSP00000460207   ENSP00000465733   ENSP00000461546  
     ENSP00000443633  

    METTL16 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for METTL16
    OriGene Protein Over-expression Lysate for METTL16
    OriGene MassSpec for METTL16
    OriGene Custom Protein Services for METTL16
    GenScript Custom Purified and Recombinant Proteins Services for METTL16
    Novus Biologicals METTL16 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    METTL16 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for METTL16
    OriGene Custom Antibody Services for METTL16
    Novus Biologicals METTL16 Antibodies
    Search for Antibodies for METTL16 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for METTL16
    LSBio Antibodies in human, mouse, rat for METTL16

    METTL16 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for METTL16
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for METTL16
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.

    Domains /
    Families
    for METTL16 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 2 InterPro protein domains:
     IPR010286 rRNA_lsu_MeTfrase_F-like
     IPR017182 S-AdoMet-dep_MeTrfase_Mett10D

    Graphical View of Domain Structure for InterPro Entry Q86W50

    ProtoNet protein and cluster: Q86W50

    UniProtKB/Swiss-Prot: MET16_HUMAN, Q86W50
    Similarity: Belongs to the methyltransferase superfamily. METTL16/RlmF family


    METTL16 for domains           About GeneDecksing


    Function
    for METTL16 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MET16_HUMAN, Q86W50
    Function: Probable methyltransferase (By similarity)

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    METTL16 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for METTL16
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for METTL16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL16

    miRNA
    Products:            		miRTarBase miRNAs that target METTL16:
    hsa-mir-92a-3p (MIRT049235), hsa-mir-26b-5p (MIRT029350), hsa-mir-193b-3p (MIRT041591), hsa-mir-423-3p (MIRT042576)

    Block miRNA regulation of human, mouse, rat METTL16 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL16 (see all 19):
    hsa-miR-644 hsa-miR-100* hsa-miR-607 hsa-miR-19b-2* hsa-miR-3692 hsa-miR-10b* hsa-miR-124 hsa-miR-506
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for METTL16
    Predesigned siRNA for gene silencing in human, mouse, rat METTL16

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for METTL16

    Clone
    Products:             		 OriGene clones in human, mouse for METTL16 (see all 8)
    OriGene ORF clones in mouse, rat for METTL16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: METTL16 (NM_024086)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL16

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for METTL16
    Browse ESI BIO Cell Lines and PureStem Progenitors for METTL16 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL16


    Localization
    for METTL16 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Pathways & Interactions
    for METTL16 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL16
    Interactions:

        Search GeneGlobe Interaction Network for METTL16

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for METTL16 (Q86W503 ENSP000002630924) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MEPCEQ7L2J03, ENSP000003085464I2D: score=1 STRING: ENSP00000308546
    SYVN1Q86TM63I2D: score=4 
    About this table

    Drugs & Compounds
    for METTL16 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for METTL16 (MET16)



    Transcripts
    for METTL16 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for METTL16 gene: 
    NM_024086.3  

    Unigene Cluster for METTL16:

    Methyltransferase like 16
    Hs.632237  [show with all ESTs]
    Unigene Representative Sequence: NM_024086
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000571332(uc002fus.3) ENST00000381977 ENST00000574623 ENST00000571669(uc010cka.3)
    ENST00000263092(uc010vqx.1 uc010vqy.1) ENST00000576556 ENST00000574752
    ENST00000571298 ENST00000576976 ENST00000577148 ENST00000538844
    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat METTL16 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL16 (see all 19):
    hsa-miR-644 hsa-miR-100* hsa-miR-607 hsa-miR-19b-2* hsa-miR-3692 hsa-miR-10b* hsa-miR-124 hsa-miR-506
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for METTL16
    Predesigned siRNA for gene silencing in human, mouse, rat METTL16
    Clone
    Products:             		 OriGene clones in human, mouse for METTL16 (see all 8)
    OriGene ORF clones in mouse, rat for METTL16
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: METTL16 (NM_024086)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL16
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for METTL16
    OriGene qSTAR qPCR primer pairs in human, mouse for METTL16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL16
      QuantiTect SYBR Green Assays in human, mouse, rat METTL16
      QuantiFast Probe-based Assays in human, mouse, rat METTL16

    Additional mRNA sequence: 

    AK027410.1 AK098286.1 AK294547.1 AK296464.1 AL832612.2 BC001213.1 BC047770.1 BC050603.1 
    BX647255.1 

    14 DOTS entries:

    DT.100784401  DT.315243  DT.95250220  DT.101982043  DT.120948776  DT.120948777  DT.100023147  DT.99948339 
    DT.91697169  DT.91711600  DT.100035865  DT.120948768  DT.92419553  DT.120948699 

    Selected AceView cDNA sequences (see all 198):

    AA594447 D31132 BM456665 AA831347 AL045793 CB215532 F04092 AI684986 
    AA931537 BX281910 AW303538 BM981103 BM838546 F00469 BU195372 BM669313 
    BX281827 Z39510 BE348790 AI791528 AI298404 AI733038 BM717274 BU162348 

    GeneLoc Exon Structure


    Expression
    for METTL16 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    METTL16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    METTL16 Expression
    About this image

    METTL16 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    METTL16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632237
        Custom PCR Arrays for METTL16
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for METTL16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL16
    QuantiTect SYBR Green Assays in human, mouse, rat METTL16
    QuantiFast Probe-based Assays in human, mouse, rat METTL16
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL16

    Orthologs
    for METTL16 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for METTL16 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Mettl161 , 5 methyltransferase like 161, 5 86.47(n)1
    89.49(a)1    		   11 (45.76 cM)5
    674931  NM_026197.31  NP_080473.11 
     747708305 
    chicken
    (Gallus gallus)    		 Aves METTL161 methyltransferase like 16 71.15(n)
    77.02(a)    		   431184  NM_001031602.1  NP_001026773.1 
    lizard
    (Anolis carolinensis)    		 Reptilia METTL166
    		 methyltransferase like 16
    		 71(a)
    		 1 ↔ 1
    		 6(66088934-66115751)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.76472 Xenopus laevis transcribed sequence with moderate similarity to protein refNP_076991.1 (H.sapiens) hypothetical protein MGC3329 [Homo sapiens] less 79(n)    BU913728.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii mettl161 methyltransferase like 16 71.84(n)
    80.37(a)    		   445217  NM_001003611.1  NP_001003611.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG75441 CG7544 51(n)
    45.23(a)    		   36680  NM_137171.4  NP_611015.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea mett-101 mett-10 48.71(n)
    42.26(a)    		   191526  NM_066846.4  NP_499247.2 


    ENSEMBL Gene Tree for METTL16 (if available)
    TreeFam Gene Tree for METTL16 (if available)

    Paralogs
    for METTL16 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Genomic Variants
    for METTL16 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for METTL16 (see all 1927)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs118682211,2
    		H--2320798(+) ATTCTC/TTGGAA 1 -- ut314Minor allele frequency- T:0.00NS EA 418
    rs1920366441,2
    		--2320808(+) AATCCC/TTACGA 1 -- ut310--------
    rs758104161,2
    		C,F--2320839(+) CTGTGC/TCTGAA 1 -- ut311Minor allele frequency- T:0.07WA 118
    rs1455554121,2
    		--2320857(+) TTGAAC/TAGGCA 1 -- ut310--------
    rs1489111901,2
    		--2321027(+) AACACA/GCCAAT 1 -- ut310--------
    rs762921121,2
    		C--2321106(+) CAAATC/TTTTAA 1 -- ut310--------
    rs1816694741,2
    		--2321176(+) GAATGA/TATAGT 1 -- ut310--------
    rs1865213951,2
    		--2321224(+) AACTAC/GGTTTG 1 -- ut310--------
    rs50153421,2
    		C,F,A,H--2321253(+) AATGTA/GATATT 1 -- ut3131Minor allele frequency- G:0.48NS EA NA WA CSA 2922
    rs1909157681,2
    		--2321392(+) ACATGA/TATGCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for METTL16 (2308856 - 2415200 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for METTL16:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669015CNV Deletion23128226
    esv2675053CNV Deletion23128226
    nsv907532CNV Loss21882294
    nsv819217CNV Loss19587683
    esv22012CNV Loss19812545
    nsv833338CNV Loss17160897
    nsv111844CNV Loss16902084
    nsv907538CNV Loss21882294
    nsv907539CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing METTL16
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL16

    Disorders / Diseases
    for METTL16 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for METTL16:    
    About MalaCards
    malaria


    METTL16 for disorders           About GeneDecksing


    Export disorders for METTL16 gene to outside databases

    Publications
    for METTL16 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for METTL16 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with METTL16)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel. (PubMed id 18021804)1, 3 Sergiev P.V....Dontsova O.A. (J. Mol. Biol. 2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities. (PubMed id 20602751)1 Docherty S.J....Plomin R. (BMC Genet. 2010)
    7. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (Mol. Cell 2008)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    9. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1 Jeronimo C.... Coulombe B. (Mol. Cell 2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

    External Searches for METTL16 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
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    Genome Databases showing METTL16 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 79066 HGNC: 28484 AceView: MGC3329 Ensembl:ENSG00000127804 euGenes: HUgn79066
    ECgene: METTL16 H-InvDB: METTL16

    Other Databases showing METTL16 gene

    (According to HUGE)
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    Specialized Databases showing METTL16 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for METTL16 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for METTL16 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for METTL16 gene:
    Search GeneIP for patents involving METTL16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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