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METTL15 Gene

protein-coding   GIFtS: 44
GCID: GC11P028129

Methyltransferase Like 15

(Previous name: methyltransferase 5 domain containing 1)
(Previous symbol: METT5D1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Methyltransferase Like 151 2     Probable Methyltransferase-Like Protein 152
METT5D11 2 3     Probable S-Adenosyl-L-Methionine-Dependent Methyltransferase METT5D12
Methyltransferase 5 Domain Containing 11 2     Putative S-Adenosyl-L-Methionine-Dependent Methyltransferase METT5D12
Methyltransferase 5 Domain-Containing Protein 12 3     EC 2.1.1.-3

External Ids:    HGNC: 266061   Entrez Gene: 1960742   Ensembl: ENSG000001695197   UniProtKB: A6NJ783   

Export aliases for METTL15 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL15 Gene:
METTL15 (methyltransferase like 15) is a protein-coding gene. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: MET15_HUMAN, A6NJ78
Function: Probable S-adenosyl-L-methionine-dependent methyltransferase (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for METTL15
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMETTL15 promoter sequence
   Search Chromatin IP Primers for METTL15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p14.1   Ensembl cytogenetic band:  11p14.1   HGNC cytogenetic band: 11p14.1

METTL15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL15 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P028129:  view genomic region     (about GC identifiers)

Start:
28,129,795 bp from pter      End:
28,355,054 bp from pter
Size:
225,260 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MET15_HUMAN, A6NJ78 (See protein sequence)
Recommended Name: Probable methyltransferase-like protein 15  
Size: 407 amino acids; 46121 Da
Sequence caution: Sequence=AAH30997.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8MRS5 B7WNU2 Q3MHD3 Q8N601 Q8NBA7
Alternative splicing: 4 isoforms:  A6NJ78-1   A6NJ78-2   A6NJ78-3   A6NJ78-4   

Explore the universe of human proteins at neXtProt for METTL15: NX_A6NJ78

Explore proteomics data for METTL15 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys352, Lys381
  • Modification sites at PhosphoSitePlus

  • See METTL15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001107000.1  NP_689849.2  

    ENSEMBL proteins: 
     ENSP00000385507   ENSP00000385860   ENSP00000396550   ENSP00000384369   ENSP00000307251  
     ENSP00000392806   ENSP00000342259   ENSP00000368497  

    METTL15 Human Recombinant Protein Products:

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    Novus Biologicals METTL15 Protein
    Novus Biologicals METTL15 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for METTL15 

    METTL15 Antibody Products:

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    ThermoFisher Antibodies for METTL15
    LSBio Antibodies in human, mouse, rat for METTL15

    METTL15 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for METTL15 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR023397 SAM-dep_MeTrfase_MraW_recog
     IPR002903 RsmH

    Graphical View of Domain Structure for InterPro Entry A6NJ78

    ProtoNet protein and cluster: A6NJ78

    UniProtKB/Swiss-Prot: MET15_HUMAN, A6NJ78
    Similarity: Belongs to the methyltransferase superfamily. RsmH family


    Find genes that share domains with METTL15           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MET15_HUMAN, A6NJ78
    Function: Probable S-adenosyl-L-methionine-dependent methyltransferase (By similarity)

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity IEA--
         
    Find genes that share ontologies with METTL15           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for METTL15
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for METTL15

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL15
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL15

    miRNA
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    Block miRNA regulation of human, mouse, rat METTL15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate METTL15 (see all 14):
    hsa-miR-3671 hsa-miR-653 hsa-miR-607 hsa-miR-539 hsa-miR-944 hsa-miR-138-2* hsa-miR-4282 hsa-miR-656
    SwitchGear 3'UTR luciferase reporter plasmidMETTL15 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for METTL15
    Predesigned siRNA for gene silencing in human, mouse, rat METTL15

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): METTL15 (NM_001113528)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL15

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for METTL15 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL15


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL15
    Interactions:

        Search GeneGlobe Interaction Network for METTL15

    1 Interacting protein for METTL15 (A6NJ783) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LONRF2Q1L5Z93I2D: score=4 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for METTL15 (MET15)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for METTL15 gene (2 alternative transcripts): 
    NM_001113528.1  NM_152636.2  

    Unigene Cluster for METTL15:

    Methyltransferase like 15
    Hs.243326  [show with all ESTs]
    Unigene Representative Sequence: NM_152636
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000406787(uc001mse.2) ENST00000403099 ENST00000451385 ENST00000407364
    ENST00000303459 ENST00000437814(uc001msf.1) ENST00000468295 ENST00000342303(uc001msg.2 uc001msh.2)
    ENST00000379199
    miRNA
    Products:
         
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    Selected qRT-PCR Assays for microRNAs that regulate METTL15 (see all 14):
    hsa-miR-3671 hsa-miR-653 hsa-miR-607 hsa-miR-539 hsa-miR-944 hsa-miR-138-2* hsa-miR-4282 hsa-miR-656
    SwitchGear 3'UTR luciferase reporter plasmidMETTL15 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for METTL15
    Predesigned siRNA for gene silencing in human, mouse, rat METTL15
    Clone
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    OriGene clones in human, mouse for METTL15 (see all 12)
    OriGene ORF clones in mouse, rat for METTL15
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): METTL15 (NM_001113528)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL15
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for METTL15
    OriGene qSTAR qPCR primer pairs in human, mouse for METTL15
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL15
      QuantiTect SYBR Green Assays in human, mouse, rat METTL15
      QuantiFast Probe-based Assays in human, mouse, rat METTL15

    Additional mRNA sequence: 

    AK091261.1 AK091298.1 AL832668.1 BC030997.1 BC066900.1 BC105287.1 

    10 DOTS entries:

    DT.100021392  DT.40308369  DT.309227  DT.100745155  DT.402985  DT.430789  DT.99993289  DT.99971248 
    DT.120841679  DT.97777549 

    Selected AceView cDNA sequences (see all 66):

    AW615337 AI569925 AA398002 BM477529 AI004348 AL558515 AA778108 AL713720 
    CR601005 AI433420 BM550252 AW081066 BE709976 AA251906 AK091298 BI035258 
    CB048279 BU615554 AK091261 BU615240 BC066900 AI637581 BG721730 BC030997 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for METTL15    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b
    SP1:                          -     -     -                 -           -               
    SP2:                          -     -     -                                             
    SP3:                          -     -     -                             -               
    SP4:                                                                                    


    ECgene alternative splicing isoforms for METTL15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    METTL15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGTTGGAA
    METTL15 Expression
    About this image

    METTL15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    METTL15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.243326
        Custom PCR Arrays for METTL15
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL15

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for METTL15 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mettl151 , 5 methyltransferase like 151, 5 80.79(n)1
    78.82(a)1
      2 (56.52 cM)5
    768941  NM_029790.31  NP_084066.21 
     1090922975 
    chicken
    (Gallus gallus)
    Aves METTL151 methyltransferase like 15 70.77(n)
    67.84(a)
      421606  NM_001199422.1  NP_001186351.1 
    lizard
    (Anolis carolinensis)
    Reptilia METTL156
    methyltransferase like 15
    76(a)
    1 ↔ 1
    GL343314.1(841533-853481)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.39632 Xenopus laevis transcribed sequence with weak similarity more 75.19(n)    BX843120.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5605731 probable methyltransferase-like protein 15-like 60.5(n)
    58.81(a)
      560573  XM_002662836.2  XP_002662882.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG146831 CG14683 51.38(n)
    47.08(a)
      41278  NM_176455.2  NP_788632.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G109101 AT5G10910 47.04(n)
    37.75(a)
      830958  NM_121129.3  NP_196652.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01376001 Os02g0137600 45.99(n)
    35.44(a)
      4328239  NM_001052366.1  NP_001045831.1 


    ENSEMBL Gene Tree for METTL15 (if available)
    TreeFam Gene Tree for METTL15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for METTL15 gene
    1 SIMAP similar gene for METTL15 using alignment to 3 protein entries:     MET15_HUMAN (see all proteins):
    METTL15P1

    Find genes that share paralogs with METTL15           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for METTL15
    PGOHUM00000239484 PGOHUM00000250267 PGOHUM00000241663


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for METTL15 (see all 3785)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1911656941,2
    --28131776(+) GCGGAA/GCCAAA 2 -- ut510--------
    rs1821780411,2
    C--28131793(+) CGGTCC/GTCAGT 2 -- ut510--------
    rs1395726771,2
    --28131883(+) AGGTTC/GTCCTG 2 -- ut510--------
    rs1879449401,2
    --28132043(+) GAGCAA/GAAGAA 2 -- int10--------
    rs1443066381,2
    --28132052(+) AAAAAC/TACGCC 2 -- int10--------
    rs773630661,2
    C,F--28132109(+) AGTTTC/TCGAAT 2 -- int11Minor allele frequency- T:0.06EA 120
    rs1465446661,2
    --28132250(+) TTCAAA/GCAGGA 2 -- int10--------
    rs1409631951,2
    --28132262(+) TTCCCA/TGCCAG 2 -- int10--------
    rs1499511531,2
    --28132372(+) TGGCAA/GTTTTA 2 -- int10--------
    rs1925820151,2
    --28132400(+) AGTGAA/GCTTTG 2 -- int10--------

    HapMap Linkage Disequilibrium report for METTL15 (28129795 - 28355054 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for METTL15:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670715CNV Deletion23128226
    dgv1057n71CNV Loss21882294
    nsv897150CNV Loss21882294
    nsv38603CNV Loss16902084
    nsv832096CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing METTL15
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for METTL15 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with METTL15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (Nature 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 196074 HGNC: 26606 AceView: FLJ33979 Ensembl:ENSG00000169519 euGenes: HUgn196074
    ECgene: METTL15 H-InvDB: METTL15

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for METTL15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for METTL15 gene:
    Search GeneIP for patents involving METTL15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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