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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

METTL14 Gene

protein-coding   GIFtS: 49
GCID: GC04P119621

Methyltransferase Like 14

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Methyltransferase Like 141 2
Methyltransferase-Like Protein 142
EC 2.1.1.-3
KIAA16273

External Ids:    HGNC: 293301   Entrez Gene: 577212   Ensembl: ENSG000001453887   UniProtKB: Q9HCE53   

Export aliases for METTL14 gene to outside databases

Previous GC identifers: GC04P119825 GC04P119607 GC04P115328


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for METTL14 Gene: 
METTL14 (methyltransferase like 14) is a protein-coding gene. Diseases associated with METTL14 include alcohol dependence, and alcoholism. GO annotations related to this gene include mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity.

UniProtKB/Swiss-Prot: MET14_HUMAN, Q9HCE5
Function: Probable methyltransferase (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the METTL14 gene promoter:
         LHX3b/Lhx3b   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   Cdc5   NF-AT   NF-AT4   NF-AT2   NF-AT3   NF-AT1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for METTL14

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat METTL14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q26   Ensembl cytogenetic band:  4q26   HGNC cytogenetic band: 4q26

METTL14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL14 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P119621:  view genomic region     (about GC identifiers)

Start:
119,606,523 bp from pter      End:
119,633,806 bp from pter
Size:
27,284 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MET14_HUMAN, Q9HCE5 (See protein sequence)
Recommended Name: Methyltransferase-like protein 14  
Size: 456 amino acids; 52150 Da
Sequence caution: Sequence=BAB13453.1; Type=Erroneous initiation;
Secondary accessions: A6NIG1 Q969V2

Explore the universe of human proteins at neXtProt for METTL14: NX_Q9HCE5

Explore proteomics data for METTL14 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9HCE5

  • METTL14 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    METTL14 Protein Expression
    REFSEQ proteins: NP_066012.1  
    ENSEMBL proteins: 
     ENSP00000373474   ENSP00000424111   ENSP00000425460  

    Human Recombinant Protein Products for METTL14: 
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    OriGene Protein Over-expression Lysate for METTL14
    OriGene MassSpec for METTL14 
    OriGene Custom Protein Services for METTL14
    GenScript Custom Purified and Recombinant Proteins Services for METTL14
    Novus Biologicals METTL14 Protein
    Novus Biologicals METTL14 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for METTL14 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    METTL14 for ontologies           About GeneDecksing



    METTL14 Antibody Products: 
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    Cloud-Clone Corp. Antibodies for METTL14 
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    LSBio Antibodies in human, mouse, rat for METTL14 

    Assay Products for METTL14: 
    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for METTL14 
    Cloud-Clone Corp. CLIAs for METTL14


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007757 MT-A70-like

    Graphical View of Domain Structure for InterPro Entry Q9HCE5

    ProtoNet protein and cluster: Q9HCE5

    1 Blocks protein domain: IPB007757 MT-A70

    UniProtKB/Swiss-Prot: MET14_HUMAN, Q9HCE5
    Similarity: Belongs to the MT-A70-like family


    METTL14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MET14_HUMAN, Q9HCE5
    Function: Probable methyltransferase (By similarity)

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity ----
    GO:0016422mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity ISS--
         
    METTL14 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for METTL14:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for METTL14 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for METTL14

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL14 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL14 

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate METTL14:
    hsa-miR-146a* hsa-miR-549
    SwitchGear 3'UTR luciferase reporter plasmidMETTL14 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for METTL14
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    Gene Editing
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    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for METTL14 (see all 7)
    OriGene ORF clones in mouse, rat for METTL14
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: METTL14 (NM_020961)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL14
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                         Customized lentivirus expression plasmids for stable overexpression of METTL14 

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    Search LifeMap BioReagents cell lines for METTL14
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL14


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for METTL14

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/17 Interacting proteins for METTL14 (Q9HCE53 ENSP000003734744) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    METTL3Q86U443, ENSP000002987174I2D: score=5 STRING: ENSP00000298717
    NUB1Q9Y5A73I2D: score=5 
    RASSF8Q8NHQ83I2D: score=5 
    RHOT1Q8IXI23I2D: score=5 
    PRPF3O433953I2D: score=4 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001510RNA methylation ISS--
    GO:0006139nucleobase-containing compound metabolic process ----

    METTL14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for METTL14 (MET14)

    Search CenterWatch for drugs/clinical trials and news about METTL14 / MET14

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for METTL14 gene: 
    NM_020961.2  

    Unigene Cluster for METTL14:

    Methyltransferase like 14
    Hs.657806  [show with all ESTs]
    Unigene Representative Sequence: BC007449
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000388822(uc003icf.3) ENST00000506780 ENST00000508801 ENST00000502564

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat METTL14
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate METTL14:
    hsa-miR-146a* hsa-miR-549
    SwitchGear 3'UTR luciferase reporter plasmidMETTL14 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for METTL14
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat METTL14
    Clone
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    OriGene clones in human, mouse for METTL14 (see all 7)
    OriGene ORF clones in mouse, rat for METTL14
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: METTL14 (NM_020961)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL14
    Sirion Biotech Customized lentivirus for stable overexpression of METTL14 
                         Customized lentivirus expression plasmids for stable overexpression of METTL14 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for METTL14
    OriGene qSTAR qPCR primer pairs in human, mouse for METTL14
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL14
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL14

    Additional mRNA sequence: 

    AB046847.1 AK055555.1 AK296056.1 BC006565.2 BC007449.2 

    8 DOTS entries:

    DT.40130889  DT.100696203  DT.100733526  DT.97802869  DT.102825324  DT.95272285  DT.95272288  DT.103999 

    24/127 AceView cDNA sequences (see all 127):

    AB046847 CB116300 BP369273 BU507384 BC007449 BM720882 AA789116 AA886975 
    BX105605 BF111931 BQ718849 BC006565 NM_020961 AW138164 AA779066 CR614338 
    AL598989 AA866199 BP356614 AA354181 BU078213 BG184673 CA391921 BX951390 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for METTL14    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:              -                                                           -     -                           
    SP2:                                                                                                            
    SP3:              -                       -                                                                     
    SP4:                                                                                                            


    ECgene alternative splicing isoforms for METTL14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    METTL14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTAGTGCTGA
    METTL14 Expression
    About this image


    See METTL14 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for METTL14

    SOURCE GeneReport for Unigene cluster: Hs.657806
        SABiosciences Custom PCR Arrays for METTL14
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for METTL14 gene from 9/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mettl141 , 5 methyltransferase like 141, 5 91.23(n)1
    98.68(a)1
      3 (53.96 cM)5
    2105291  NM_201638.21  NP_964000.21 
     1233646455 
    chicken
    (Gallus gallus)
    Aves METTL141 methyltransferase like 14 83.11(n)
    94.74(a)
      422684  NM_001031148.1  NP_001026319.1 
    lizard
    (Anolis carolinensis)
    Reptilia METTL146
    methyltransferase like 14
    93(a)
    1 ↔ 1
    5(140373875-140396560)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.76342 Xenopus laevis transcribed sequence with weak similarity more 77.58(n)    BU901089.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mettl141 methyltransferase like 14 72.71(n)
    84.96(a)
      404603  NM_207071.1  NP_996954.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG78181 CG7818 58.85(n)
    66.49(a)
      34138  NM_135361.2  NP_609205.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes KAR46
    Transcription factor required for gene regulation ...
    26(a)
    1 ↔ 1
    III(27929-28936)
    soybean
    (Glycine max)
    eudicotyledons Gma.104862 Transcribed sequence with strong similarity to protein more 74.08(n)    BM188576.1 
    rice
    (Oryza sativa)
    Liliopsida Os.225082 Oryza sativa (japonica cultivar-group) cDNA clone0 more 73.03(n)    AK065023.1 


    ENSEMBL Gene Tree for METTL14 (if available)
    TreeFam Gene Tree for METTL14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/536 SNPs in METTL14 are shown (see all 536)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs782706391,2
    C,F--115326344(+) GAGCAA/CAAAGG 1 -- us2k11Minor allele frequency- C:0.08EA 120
    rs1139884201,2
    F--115326454(+) GCAAAC/TTCACT 1 -- us2k12Minor allele frequency- T:0.50CSA 4
    rs1860843211,2
    --115326502(+) GAGGGG/TCTGCT 1 -- us2k10--------
    rs2989831,2
    C,F,A--115326544(-) AGAGCA/GATGAC 1 -- us2k111Minor allele frequency- G:0.41NA WA CSA EA 374
    rs1464942161,2
    --115326603(+) TTCCAC/TCTTTT 1 -- us2k10--------
    rs1399622831,2
    --115326637(+) GGGCAA/GAGTCT 1 -- us2k10--------
    rs1152063711,2
    C--115326734(+) AGTATA/GGGGTT 1 -- us2k10--------
    rs2989821,2
    C,F,O,A,H--115326751(-) CTTGCC/TTGTAA 1 -- us2k1 tfbs319Minor allele frequency- T:0.26EA NA NS WA CSA 1004
    rs98849781,2
    C,F,A--115326786(+) AAAAAG/AAAAAA 1 -- us2k1 trp36Minor allele frequency- A:0.30NA WA 144
    rs2009713181,2
    --115326786(+) AAAAA-/GAAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for METTL14 (119606523 - 119633806 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for METTL14:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv519017CNV Loss19592680
    essv11621CNV CNV17122850
    dgv1668e1CNV Complex17122850


    Human Gene Mutation Database (HGMD): METTL14
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing METTL14
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for METTL14:    About MalaCards
    alcohol dependence    alcoholism


    METTL14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): METTL14
    Human Genome Epidemiology (HuGE) Navigator: METTL14 (1 document)

    Export disorders for METTL14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for METTL14 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with METTL14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1, 4 Kalsi G....Riley B.P. (2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57721 HGNC: 29330 AceView: KIAA1627 Ensembl:ENSG00000145388 euGenes: HUgn57721
    ECgene: METTL14 H-InvDB: METTL14

    (According to HUGE)
    About This Section
    HUGE: KIAA1627

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for METTL14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for METTL14 gene:
    Search GeneIP for patents involving METTL14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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