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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

METTL13 Gene

protein-coding   GIFtS: 52
GCID: GC01P171750

Methyltransferase Like 13

(Previous name: KIAA0859)
(Previous symbol: KIAA0859)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Methyltransferase Like 131 2     feat2
KIAA08591 2 3     Methyltransferase-Like Protein 132
5630401D24Rik2     EC 2.1.1.-3
Antiapoptotic Protein FEAT2     

External Ids:    HGNC: 242481   Entrez Gene: 516032   Ensembl: ENSG000000101657   UniProtKB: Q8N6R03   

Export aliases for METTL13 gene to outside databases

Previous GC identifers: GC01P170018 GC01P142974


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for METTL13 Gene: 
METTL13 (methyltransferase like 13) is a protein-coding gene. Diseases associated with METTL13 include exhibitionism, and smallpox. GO annotations related to this gene include methyltransferase activity.

Gene Wiki entry for METTL13 (KIAA0859) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the METTL13 gene promoter:
         SRF   c-Fos   AP-1   MIF-1   AP-2gamma   Roaz   MZF-1   Zic1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMETTL13 promoter sequence
   Search SABiosciences Chromatin IP Primers for METTL13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat METTL13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24-q25.3   Ensembl cytogenetic band:  1q24.3   HGNC cytogenetic band: 1q24-q25.3

METTL13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL13 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P171750:  view genomic region     (about GC identifiers)

Start:
171,750,761 bp from pter      End:
171,783,163 bp from pter
Size:
32,403 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MET13_HUMAN, Q8N6R0 (See protein sequence)
Recommended Name: Methyltransferase-like protein 13  
Size: 699 amino acids; 78768 Da
Sequence caution: Sequence=BAA74882.2; Type=Erroneous initiation; Sequence=BAD97213.1; Type=Erroneous initiation;
Secondary accessions: A6NFK0 A8K6S5 O94940 Q53EZ6 Q5TGP9 Q5TGQ0 Q8N2P8 Q96J11 Q96SQ0 Q9Y2Z1
Q9Y3M6
Alternative splicing: 5 isoforms:  Q8N6R0-5   Q8N6R0-4   Q8N6R0-3   Q8N6R0-1   Q8N6R0-2   

Explore the universe of human proteins at neXtProt for METTL13: NX_Q8N6R0

Explore proteomics data for METTL13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N6R0

  • METTL13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    METTL13 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001007240.1  NP_055770.1  NP_057019.3  

    ENSEMBL proteins: 
     ENSP00000355393   ENSP00000356711   ENSP00000354920   ENSP00000356710   ENSP00000401955  

    Human Recombinant Protein Products for METTL13: 
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    OriGene MassSpec for METTL13 
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    Novus Biologicals METTL13 Protein
    Novus Biologicals METTL13 Lysate
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for METTL13 


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    LSBio Antibodies in human, mouse, rat for METTL13 

    Assay Products for METTL13: 
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    Cloud-Clone Corp. ELISAs for METTL13 
    Cloud-Clone Corp. CLIAs for METTL13


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR013216 Methyltransf_11

    Graphical View of Domain Structure for InterPro Entry Q8N6R0

    ProtoNet protein and cluster: Q8N6R0

    1 Blocks protein domain: IPB013216 Methyltransferase type 11

    UniProtKB/Swiss-Prot: MET13_HUMAN, Q8N6R0
    Similarity: Belongs to the methyltransferase superfamily


    METTL13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0008168methyltransferase activity IEA--
         
    METTL13 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for METTL13:
     Increased G2M DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for METTL13 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for METTL13

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL13 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL13 

    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate METTL13:
    hsa-miR-668 hsa-miR-3910 hsa-miR-4330 hsa-miR-622
    SwitchGear 3'UTR luciferase reporter plasmidMETTL13 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of METTL13 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL13


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for METTL13

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/589 Interacting proteins for METTL13 (Q8N6R02, 3 ENSP000003549204) via UniProtKB, MINT, STRING, and/or I2D (see all 589)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=2 STRING: ENSP00000367207
    SNW1Q135732, ENSP000002615314MINT-7945693 STRING: ENSP00000261531
    PHKA2P460193I2D: score=4 
    THAP1Q9NVV93I2D: score=1 
    ABCF1Q8NE712MINT-7945693
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    METTL13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for METTL13 (MET13)

    Search CenterWatch for drugs/clinical trials and news about METTL13 / MET13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for METTL13 gene (3 alternative transcripts): 
    NM_001007239.1  NM_014955.2  NM_015935.4  

    Unigene Cluster for METTL13:

    Methyltransferase like 13
    Hs.494705  [show with all ESTs]
    Unigene Representative Sequence: NM_015935
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485629 ENST00000362019(uc001gia.3) ENST00000367737(uc001gib.3)
    ENST00000361735(uc001ghz.3 uc010pml.2) ENST00000367736 ENST00000478330
    ENST00000466643 ENST00000476386 ENST00000458517
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat METTL13
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate METTL13:
    hsa-miR-668 hsa-miR-3910 hsa-miR-4330 hsa-miR-622
    SwitchGear 3'UTR luciferase reporter plasmidMETTL13 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for METTL13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat METTL13
    Clone
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    OriGene clones in human, mouse for METTL13 (see all 16)
    OriGene ORF clones in mouse, rat for METTL13
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    GenScript: all cDNA clones in your preferred vector (see all 3): METTL13 (NM_014955)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL13
    Sirion Biotech Customized lentivirus for stable overexpression of METTL13 
                         Customized lentivirus expression plasmids for stable overexpression of METTL13 
    Primer
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    OriGene qPCR primer pairs and template standards for METTL13
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL13
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL13

    Additional mRNA sequence: 

    AB020666.2 AB242174.1 AB242175.1 AF132936.1 AK001172.1 AK027552.1 AK027621.1 AK027886.1 
    AK074552.1 AK129561.1 AK223493.1 AK291740.1 AK304471.1 AL049669.1 BC006814.1 BC029083.1 

    13 DOTS entries:

    DT.100791536  DT.95227710  DT.95227707  DT.99933323  DT.315359  DT.97848272  DT.95133741  DT.100791534 
    DT.121462685  DT.121462755  DT.100728579  DT.121462695  DT.121462742 

    24/296 AceView cDNA sequences (see all 296):

    BU931456 AK094818 BQ940791 AL049669 CD656212 AI608613 BC006814 CB270219 
    AI799181 NM_015935 BM661479 BE048500 H89315 BU844583 AI824580 CR595608 
    CB529141 BM472207 F27871 AA885715 AB020666 AA600908 CB133991 CB126290 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for METTL13 (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c
    SP1:                                                                                                                          -                     
    SP2:                                -     -                                                                                   -                     
    SP3:                                                        -     -     -                                                     -                     
    SP4:                                                                                                        -                                       
    SP5:                                                                                                        -                 -                     


    ECgene alternative splicing isoforms for METTL13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    METTL13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGACCTCCAG
    METTL13 Expression
    About this image


    See METTL13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for METTL13

    SOURCE GeneReport for Unigene cluster: Hs.494705
        SABiosciences Custom PCR Arrays for METTL13
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for METTL13 gene from 9/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mettl131 , 5 methyltransferase like 131, 5 87.57(n)1
    90.24(a)1
      1 (70.29 cM)5
    714491  NM_144877.11  NP_659126.11 
     1625321275 
    chicken
    (Gallus gallus)
    Aves METTL131 methyltransferase like 13 71.14(n)
    69.93(a)
      100857481  XM_003641654.1  XP_003641702.1 
    lizard
    (Anolis carolinensis)
    Reptilia METTL136
    Uncharacterized protein
    64(a)
    1 ↔ 1
    GL343300.1(1168244-1183995)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480358952   -- 77.22(n)    48035895 
    zebrafish
    (Danio rerio)
    Actinopterygii mettl131 methyltransferase like 13 57.77(n)
    56.11(a)
      557908  NM_001044769.2  NP_001038234.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG26141 CG2614 53.03(n)
    46.71(a)
      35326  NM_136201.4  NP_610045.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_C01B10.81 Protein C01B10.8 44.04(n)
    37.36(a)
      177431  NM_068623.2  NP_501024.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G317401 S-adenosylmethionine-dependent methyltransferase domain-containing more 45.34(n)
    36.79(a)
      817731  NM_179840.1  NP_850171.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g03793001 hypothetical protein 45(n)
    35.76(a)
      4335621  NM_001059123.1  NP_001052588.1 


    ENSEMBL Gene Tree for METTL13 (if available)
    TreeFam Gene Tree for METTL13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for METTL13 gene
    1 SIMAP similar gene for METTL13 using alignment to 3 protein entries:     MET13_HUMAN (see all proteins):
    feat

    METTL13 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/489 SNPs in METTL13 are shown (see all 489)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0647304
    ----see VAR_0647302 Y C mis40--------
    rs1157603031,2
    C,F--171748766(+) AGAGGG/AAGTCT 3 -- us2k11Minor allele frequency- A:0.04WA 118
    rs109136511,2
    C,F,A--171748774(+) TCTCCC/TTCTGT 3 -- us2k1 tfbs310Minor allele frequency- T:0.43NA WA EA 372
    rs1467283351,2
    C--171748817(+) TGGCTC/TACTGC 3 -- us2k10--------
    rs1403168461,2
    C--171748904(+) ACGCTC/TGGCTA 3 -- us2k10--------
    rs1454510311,2
    C--171749024(+) CAGGCA/GTGAGC 3 -- us2k10--------
    rs1464669431,2
    --171749102(+) TCCTCC/TGCTCT 3 -- us2k10--------
    rs1490547701,2
    C--171749166(+) TGTAGA/TAGCTG 3 -- us2k10--------
    rs1913801821,2
    --171749195(+) CTCCTC/TCTCTT 3 -- us2k10--------
    rs566926201,2
    C,F--171749353(+) AACAGC/TGGTTC 3 -- us2k11Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for METTL13 (171750761 - 171783163 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for METTL13:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv518222CNV Loss19592680
    nsv872545CNV Loss21882294
    nsv522889CNV Loss19592680
    esv5613CNV Gain19470904

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing METTL13
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for METTL13:    About MalaCards
    exhibitionism    smallpox    gastric cancer

    1 disease from the University of Copenhagen DISEASES database for METTL13:
    Exhibitionism

    METTL13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): METTL13

    Export disorders for METTL13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for METTL13 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with METTL13)
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    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T....Ohara O. (1998)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    7. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. A novel potent tumour promoter aberrantly overexpresse d in most human cancers. (PubMed id 22355534)1 Takahashi A....Tani K. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51603 HGNC: 24248 AceView: CGI-01 Ensembl:ENSG00000010165 euGenes: HUgn51603
    ECgene: METTL13 H-InvDB: METTL13

    (According to HUGE)
    About This Section
    HUGE: KIAA0859

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for METTL13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for METTL13 gene:
    Search GeneIP for patents involving METTL13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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