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METTL13 Gene

protein-coding   GIFtS: 54
GCID: GC01P171750

Methyltransferase Like 13

(Previous name: KIAA0859)
(Previous symbol: KIAA0859)
  See METTL13-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Methyltransferase Like 131 2     feat2
KIAA08591 2 3     Methyltransferase-Like Protein 132
5630401D24Rik2     EC 2.1.1.-3
Antiapoptotic Protein FEAT2     

External Ids:    HGNC: 242481   Entrez Gene: 516032   Ensembl: ENSG000000101657   UniProtKB: Q8N6R03   
ORGUL members:         

Export aliases for METTL13 gene to outside databases

Previous GC identifers: GC01P170018 GC01P142974


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for METTL13 Gene:
METTL13 (methyltransferase like 13) is a protein-coding gene. Diseases associated with METTL13 include exhibitionism. GO annotations related to this gene include methyltransferase activity.

Gene Wiki entry for METTL13 (KIAA0859) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the METTL13 gene promoter:
         SRF   c-Fos   AP-1   MIF-1   AP-2gamma   Roaz   MZF-1   Zic1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMETTL13 promoter sequence
   Search Chromatin IP Primers for METTL13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat METTL13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24-q25.3   Ensembl cytogenetic band:  1q24.3   HGNC cytogenetic band: 1q24-q25.3

METTL13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
METTL13 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P171750:  view genomic region     (about GC identifiers)

Start:
171,750,761 bp from pter      End:
171,783,163 bp from pter
Size:
32,403 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MET13_HUMAN, Q8N6R0 (See protein sequence)
Recommended Name: Methyltransferase-like protein 13  
Size: 699 amino acids; 78768 Da
Sequence caution: Sequence=BAA74882.2; Type=Erroneous initiation; Sequence=BAD97213.1; Type=Erroneous initiation;
Secondary accessions: A6NFK0 A8K6S5 O94940 Q53EZ6 Q5TGP9 Q5TGQ0 Q8N2P8 Q96J11 Q96SQ0 Q9Y2Z1
Q9Y3M6
Alternative splicing: 5 isoforms:  Q8N6R0-5   Q8N6R0-4   Q8N6R0-3   Q8N6R0-1   Q8N6R0-2   

Explore the universe of human proteins at neXtProt for METTL13: NX_Q8N6R0

Explore proteomics data for METTL13 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys19, Lys252
  • Modification sites at PhosphoSitePlus

  • See METTL13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001007240.1  NP_055770.1  NP_057019.3  

    ENSEMBL proteins: 
     ENSP00000355393   ENSP00000356711   ENSP00000354920   ENSP00000401955  

    METTL13 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for METTL13

     
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    LSBio Antibodies in human, mouse, rat for METTL13

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    Search eBioscience for ELISAs for METTL13 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR013216 Methyltransf_11

    Graphical View of Domain Structure for InterPro Entry Q8N6R0

    ProtoNet protein and cluster: Q8N6R0

    1 Blocks protein domain: IPB013216 Methyltransferase type 11

    UniProtKB/Swiss-Prot: MET13_HUMAN, Q8N6R0
    Similarity: Belongs to the methyltransferase superfamily


    Find genes that share domains with METTL13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0008168methyltransferase activity IEA--
         
    Find genes that share ontologies with METTL13           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for METTL13:
     Increased G2M DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for METTL13
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for METTL13

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for METTL13
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for METTL13

    miRNA
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    miRTarBase miRNAs that target METTL13:
    hsa-mir-769-3p (MIRT039114), hsa-mir-193b-3p (MIRT041529)

    Block miRNA regulation of human, mouse, rat METTL13 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate METTL13:
    hsa-miR-668 hsa-miR-3910 hsa-miR-4330 hsa-miR-622
    SwitchGear 3'UTR luciferase reporter plasmidMETTL13 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat METTL13

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    Browse ESI BIO Cell Lines and PureStem Progenitors for METTL13 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL13


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    cytoskeleton1
    mitochondrion1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for METTL13
    Interactions:

        Search GeneGlobe Interaction Network for METTL13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for METTL13 (Q8N6R02, 3 ENSP000003549204) via UniProtKB, MINT, STRING, and/or I2D (see all 589)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=2 STRING: ENSP00000367207
    SMARCC1Q929222, ENSP000002544804MINT-7945693 STRING: ENSP00000254480
    SMARCC2Q8TAQ22, ENSP000002670644MINT-7945693 STRING: ENSP00000267064
    SNW1Q135732, ENSP000002615314MINT-7945693 STRING: ENSP00000261531
    PHKA2P460193I2D: score=4 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    Find genes that share ontologies with METTL13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for METTL13 (MET13)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for METTL13 gene (3 alternative transcripts): 
    NM_001007239.1  NM_014955.2  NM_015935.4  

    Unigene Cluster for METTL13:

    Methyltransferase like 13
    Hs.494705  [show with all ESTs]
    Unigene Representative Sequence: NM_015935
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485629 ENST00000362019(uc001gia.3) ENST00000367737(uc001gib.3)
    ENST00000361735(uc001ghz.3 uc010pml.2) ENST00000478330 ENST00000466643
    ENST00000476386 ENST00000458517
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat METTL13 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate METTL13:
    hsa-miR-668 hsa-miR-3910 hsa-miR-4330 hsa-miR-622
    SwitchGear 3'UTR luciferase reporter plasmidMETTL13 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for METTL13
    Predesigned siRNA for gene silencing in human, mouse, rat METTL13
    Clone
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    OriGene clones in human, mouse for METTL13 (see all 19)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): METTL13 (NM_014955)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for METTL13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL13
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    OriGene qPCR primer pairs and template standards for METTL13
    OriGene qSTAR qPCR primer pairs in human, mouse for METTL13
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat METTL13
      QuantiTect SYBR Green Assays in human, mouse, rat METTL13
      QuantiFast Probe-based Assays in human, mouse, rat METTL13

    Additional mRNA sequence: 

    AB020666.2 AB242174.1 AB242175.1 AF132936.1 AK001172.1 AK027552.1 AK027621.1 AK027886.1 
    AK074552.1 AK129561.1 AK223493.1 AK291740.1 AK304471.1 AL049669.1 BC006814.1 BC029083.1 

    13 DOTS entries:

    DT.100791536  DT.95227710  DT.95227707  DT.99933323  DT.315359  DT.97848272  DT.95133741  DT.100791534 
    DT.121462685  DT.121462755  DT.100728579  DT.121462695  DT.121462742 

    Selected AceView cDNA sequences (see all 296):

    NM_015935 BQ434990 CR594527 BU171924 AB020666 AI799181 AA991436 AK094818 
    AI608613 CB270219 BU616752 CB529141 BU844583 CB126290 AK027621 AL049669 
    BE302190 AI274346 BQ691144 BU521756 BQ940791 BU931456 AA600908 F37160 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for METTL13 (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c
    SP1:                                                                                                                          -                     
    SP2:                                -     -                                                                                   -                     
    SP3:                                                        -     -     -                                                     -                     
    SP4:                                                                                                        -                                       
    SP5:                                                                                                        -                 -                     


    ECgene alternative splicing isoforms for METTL13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    METTL13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGACCTCCAG
    METTL13 Expression
    About this image

    METTL13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    METTL13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.494705
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for METTL13 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mettl131 , 5 methyltransferase like 131, 5 87.57(n)1
    90.24(a)1
      1 (70.29 cM)5
    714491  NM_144877.11  NP_659126.11 
     1625321275 
    chicken
    (Gallus gallus)
    Aves METTL131 methyltransferase like 13 71.14(n)
    69.83(a)
      100857481  XM_004943192.1  XP_004943249.1 
    lizard
    (Anolis carolinensis)
    Reptilia METTL136
    methyltransferase like 13
    64(a)
    1 ↔ 1
    GL343300.1(1168244-1183995)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480358952   -- 77.22(n)    48035895 
    zebrafish
    (Danio rerio)
    Actinopterygii mettl131 methyltransferase like 13 57.12(n)
    55.26(a)
      557908  NM_001044769.3  NP_001038234.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG26141 CG2614 52.81(n)
    46.25(a)
      35326  NM_136201.5  NP_610045.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_C01B10.81 CELE_C01B10.8 43.97(n)
    37.16(a)
      177431  NM_068623.3  NP_501024.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G317401 AT2G31740 45.25(n)
    36.21(a)
      817731  NM_179840.1  NP_850171.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g03793001 Os04g0379300 44.51(n)
    35.01(a)
      4335621  NM_001059123.1  NP_001052588.1 


    ENSEMBL Gene Tree for METTL13 (if available)
    TreeFam Gene Tree for METTL13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for METTL13 gene
    1 SIMAP similar gene for METTL13 using alignment to 2 protein entries:     MET13_HUMAN (see all proteins):
    feat

    Find genes that share paralogs with METTL13           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for METTL13 (see all 489)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1157603031,2
    C,F--171748766(+) AGAGGG/AAGTCT 3 -- us2k11Minor allele frequency- A:0.04WA 118
    rs109136511,2
    C,F,A--171748774(+) TCTCCC/TTCTGT 3 -- us2k1 tfbs310Minor allele frequency- T:0.43NA WA EA 372
    rs1467283351,2
    C--171748817(+) TGGCTC/TACTGC 3 -- us2k10--------
    rs1403168461,2
    C--171748904(+) ACGCTC/TGGCTA 3 -- us2k10--------
    rs1454510311,2
    C--171749024(+) CAGGCA/GTGAGC 3 -- us2k10--------
    rs1464669431,2
    --171749102(+) TCCTCC/TGCTCT 3 -- us2k10--------
    rs1490547701,2
    C--171749166(+) TGTAGA/TAGCTG 3 -- us2k10--------
    rs1913801821,2
    --171749195(+) CTCCTC/TCTCTT 3 -- us2k10--------
    rs566926201,2
    C,F--171749353(+) AACAGC/TGGTTC 3 -- us2k11Minor allele frequency- T:0.50WA 2
    rs759299261,2
    F--171749377(+) GTTCCG/AGGACC 3 -- us2k12Minor allele frequency- A:0.08CSA WA 120

    HapMap Linkage Disequilibrium report for METTL13 (171750761 - 171783163 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for METTL13:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv518222CNV Loss19592680
    nsv872545CNV Loss21882294
    nsv522889CNV Loss19592680
    esv5613CNV Gain19470904

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing METTL13
    DNA2.0 Custom Variant and Variant Library Synthesis for METTL13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for METTL13:    
    About MalaCards
    exhibitionism

    1 disease from the University of Copenhagen DISEASES database for METTL13:
    Exhibitionism

    Find genes that share disorders with METTL13           About GenesLikeMe

    Genetic Association Database (GAD): METTL13

    Export disorders for METTL13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for METTL13 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with METTL13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    7. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    10. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51603 HGNC: 24248 AceView: CGI-01 Ensembl:ENSG00000010165 euGenes: HUgn51603
    ECgene: METTL13 H-InvDB: METTL13

    (According to HUGE)
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    HUGE: KIAA0859

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for METTL13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for METTL13 gene:
    Search GeneIP for patents involving METTL13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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