METTL1 Gene
protein-coding GIFtS: 56
GCID: GC12M058165
|
|
methyltransferase like 1(Previous name: methyltransferase-like 1 )
(Previous symbol: C12orf1)
| |
Aliases
for METTL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Methyltransferase Like 11 2 | | TRNA(M7G46)-Methyltransferase1 | | C12orf11 2 3 | | TRNA (Guanine(46)-N(7))-Methyltransferase2 3 | | TRM81 2 | | EC 2.1.1.333 8 | | TRMT81 2 | | YDL201w2 | | Methyltransferase-Like 11 2 | | D1075-Like Gene Product2 | | Methyltransferase-Like Protein 12 3 | | TRNA (Guanine-N(7)-)-Methyltransferase2 |
Export aliases for METTL1 gene to outside databasesPrevious GC identifers: GC12M057763 GC12M058305 GC12M057879 GC12M056448 GC12M058163 GC12M055199 |
Summaries
for METTL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for METTL1:
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conservedS-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encodingdifferent protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TRMB_HUMAN, Q9UBP6Function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
Gene Wiki entry for METTL1
|
Genomic Views
for METTL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the METTL1 gene promoter:
CREB deltaCREB C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for METTL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat METTL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q14.1 HGNC cytogenetic band: 12q13METTL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M058165: view genomic region
(about GC identifiers)
Start:
|
58,162,254 bp from pter |
End:
|
58,166,576 bp from pter |
Size:
|
4,323 bases |
Orientation:
|
minus strand |
|
Proteins
for METTL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRMB_HUMAN, Q9UBP6 (See
protein sequence)Recommended Name: tRNA (guanine-N(7)-)-methyltransferase Size: 276 amino acids; 31471 Da
Subunit: Forms a complex with WDR4
Subcellular location: Nucleus
Sequence caution: Sequence=CAA65470.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for METTL1:3CKK (3D)
Secondary accessions: B2RBX1 H7BXF2 Q14105 Q53FS9Alternative splicing: 2 isoforms: Q9UBP6-1 Q9UBP6-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for METTL1: NX_Q9UBP6
Post-translational modifications:
Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR41
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UBP6
4/9 DME Specific Peptides for METTL1 (Q9UBP6) (see all 9)
METTL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_005362.3 NP_075422.3
ENSEMBL proteins: ENSP00000314441 ENSP00000257848 ENSP00000447838 ENSP00000449397 ENSP00000447988 ENSP00000448342
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
METTL1 for ontologies About GeneDecksing
METTL1 Antibody Products:
Assay Products for METTL1: |
Protein
Domains /
Families
for METTL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
METTL1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UBP6ProtoNet protein and cluster: Q9UBP6 2 Blocks protein families: IPB000515 Binding-protein-dependent transport systems inner membrane component IPB003358 Putative methyltransferase
UniProtKB/Swiss-Prot: TRMB_HUMAN, Q9UBP6Similarity: Belongs to the methyltransferase superfamily. TrmB family |
Function
for METTL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TRMB_HUMAN, Q9UBP6Function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNACatalytic activity: S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46)in tRNA Genatlas biochemistry entry for METTL1:methyltransferase-like 1
Enzyme Number (IUBMB): EC 2.1.1.331 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for METTL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for METTL1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for METTL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
METTL1 for ontologies About GeneDecksing
|
Pathways & Interactions
for METTL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
UniProtKB/Swiss-Prot: TRMB_HUMAN, Q9UBP6Pathway: tRNA modification; N(7)-methylguanine-tRNA biosynthesisInteractions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for METTL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/41 Interacting proteins for METTL1 (Q9UBP63 ENSP000003144414) via UniProtKB, MINT, STRING, and/or I2D (see all 41) About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
METTL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for METTL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for METTL1
2 HMDB Compounds for METTL1 About this table
Search CenterWatch for drugs/clinical trials and news about METTL1 / TRMB
|
Transcripts
for METTL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for METTL1 gene (3 alternative transcripts): NM_005371.5 NM_023033.3 NM_023032.1 Unigene Cluster for METTL1: Methyltransferase like 1 Hs.42957 [show with all ESTs]Unigene Representative Sequence: BM8112178 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000324871(uc010ssd.2 uc009zqc.3) ENST00000257848 ENST00000547653
ENST00000548504 ENST00000551117 ENST00000553125 ENST00000548681 ENST00000549773
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for METTL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for METTL1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): METTL1 (NM_005371) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for METTL1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL1 |
Additional cDNA sequence: AK223202.1 AK314851.1 BC000550.1 X96698.1 Y18643.1 8 DOTS entries: DT.316148 DT.95206155 DT.100773472 DT.100773466 DT.101968573 DT.95078060 DT.102841110 DT.95374559 24/201 AceView cDNA sequences (see all 201): AW051280 AB005038 CA308365 BF195899 BM713851 BE293985 Y18643 CA487368 BG391631 BC000550 AA341990 CR595086 BI259784 AA962620 BE887016 BG059068 BM836364 BE294824 BQ678084 NM_000785 BC020267 AF246895 AW195105 BQ651940
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for METTL1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c |
|---|
|
| SP1: | | | | | - | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | - | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP5: | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for METTL1
|
Expression
for METTL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| METTL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATATGTGTA
About this image
See METTL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for METTL1
SOURCE GeneReport for Unigene cluster: Hs.42957
UniProtKB/Swiss-Prot: TRMB_HUMAN, Q9UBP6Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for METTL1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for METTL1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat METTL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL1 |
Orthologs
for METTL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for METTL1 gene from 9/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mettl11 , 5 |
methyltransferase like 11, 5 |
86.89(n)1
90.64(a)1 |
|
10 (74.50 cM)5
172991 NM_010792.11 NP_034922.11
1270414145 |
lizard
(Anolis carolinensis) |
Reptilia |
METTL16 |
-- |
78(a) |
1 ↔ 1 |
2(66916065-66933801) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.110512 |
Transcribed sequence with moderate similarity to protein more |
77.06(n) |
|
142003409 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.283332 |
Transcribed sequence with weak similarity to protein more |
75.9(n) |
|
CF595110.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
EG:22E5.43
CG40451 |
CG40451 |
59(a)3
64.25(n)1
64.53(a)1 |
|
2C103
311761 NM_130622.31 NP_569978.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
W02B12.101 , 3 |
Protein W02B12.101 |
59(a)3
63.19(n)1
64.78(a)1 |
|
II(11472135-11473657)3
1747531 NM_064047.21 NP_496448.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
TRM8(YDL201W)4
TRM81 |
Subunit of a tRNA methyltransferase complex composed more4
Trm8p1 |
57.71(n)1
60.74(a)1 |
|
4(99561-100421)4
8513261, 4 NP_010080.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G248401 |
tRNA (guanine-N(7)-)-methyltransferase |
59.28(n)
56.09(a) |
|
832553 NM_122393.3 NP_197866.1 |
rice
(Oryza sativa) |
Liliopsida |
Os06g02369001 |
hypothetical protein |
62.87(n)
63.29(a) |
|
4340601 NM_001063779.1 NP_001057244.1 |
ENSEMBL Gene Tree for METTL1 (if available)
TreeFam Gene Tree for METTL1 (if available) |
Paralogs
for METTL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for METTL1 gene
METTL1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for METTL1
PGOHUM00000260902
|
Genomic Variants
for METTL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for METTL1 (58162254 - 58166576 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for METTL1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing METTL1 |
|
Disorders
/ Diseases
for METTL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
METTL1 for disorders About GeneDecksing
OMIM gene information: 604466
OMIM disorders: --
5  diseases for METTL1: About MalaCardsmultiple sclerosis hypercalciuria hypercalcemia homocysteine
malaria
Human Genome Epidemiology (HuGE) Navigator: METTL1 (5 documents)
Export disorders for METTL1 gene to outside databases
|
Publications
for METTL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for METTL1 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with METTL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular analysis of METTL1, a novel human methyltransferase-like gene with a high degree of phylogenetic conservation. (PubMed id 10329009)1, 2, 3, 9 Bahr A.... Schmidt E.R. (1999)
- The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. (PubMed id 15861136)1, 2, 3 Cartlidge R.A....Cohen P. (2005)
- Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. (PubMed id 12403464)1, 2, 9 Alexandrov A.... Phizicky E.M. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1 Guey L.T....Malats N. (2010)
- Infantile hypercalcemia and hypercalciuria: new insig hts into a vitamin D-dependent mechanism and response to ketoconazole treatment . (PubMed id 20394945)1 Nguyen M....Garabedian M. (2010)
|
External Searches for METTL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing METTL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing METTL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing METTL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for METTL1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for METTL1 gene:
Search GeneIP for patents involving METTL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for METTL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for METTL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for METTL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for METTL1 | | | OriGene Protein Over-expression Lysate for METTL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for METTL1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for METTL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for METTL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for METTL1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for METTL1 | | OriGene Custom Protein Services for METTL1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat METTL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing METTL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat METTL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat METTL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat METTL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat METTL1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for METTL1 |
| |  |  |  |  | | | | | | Recombinant Protein for METTL1 |
|
 |
 |
 |
 | | | METTL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for METTL1 |
|  |  |  | | | | ThermoFisher Antibodies for METTL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat METTL1 |
|
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|
