Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MESTIT1 Gene

Subcategory (RNA class) for MESTIT1 Gene

antisense

Quality Score for this RNA gene is

3

Aliases for MESTIT1 Gene

  • MEST Intronic Transcript 1, Antisense RNA 2 3
  • MEST Intronic Transcript 1, Antisense RNA (Non-Protein Coding) 2 3
  • MEST Antisense RNA 1 (Non-Protein Coding) 2 3
  • MEST Intronic Transcript 1 (Non-Protein Coding) 3
  • Paternally Expressed Gene, Antisense Transcript 3
  • MEST Intronic Transcript (Non-Protein Coding) 3
  • Non-Protein Coding RNA 40 2
  • NCRNA00040 3
  • MEST-AS1 3
  • MEST-IT1 3
  • MEST-IT 3
  • PEG1-AS 3

External Ids for MESTIT1 Gene

ORGUL Members for MESTIT1 Gene

Previous GeneCards Identifiers for MESTIT1 Gene

  • GC07U900012
  • GC07M130126
  • GC07M124489

Summaries for MESTIT1 Gene

Entrez Gene Summary for MESTIT1 Gene

  • This gene encodes a non-protein coding antisense RNA that is imprinted, and preferentially expressed from the paternal allele. It is located in an intron of MEST gene in the opposite orientation, and shares the promoter region in common with one of the promoters (P2) of MEST gene. The antisense RNA is expressed predominantly in testis and mature motile spermatozoa, suggesting that it may be involved in the regulation of MEST expression during development.[provided by RefSeq, Oct 2010]

GeneCards Summary for MESTIT1 Gene

MESTIT1 (MEST Intronic Transcript 1, Antisense RNA) is an RNA Gene, and is affiliated with the antisense RNA class.

fRNAdb sequence ontologies for MESTIT1 Gene

  • antisense_RNA: Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MESTIT1 Gene

Genomics for MESTIT1 Gene

Regulatory Elements for MESTIT1 Gene

Genomic Location for MESTIT1 Gene

Start:
130,487,057 bp from pter
End:
130,491,172 bp from pter
Size:
4,116 bases
Orientation:
Minus strand

Genomic View for MESTIT1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MESTIT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MESTIT1 Gene

Proteins for MESTIT1 Gene

Post-translational modifications for MESTIT1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MESTIT1 Gene

Domains for MESTIT1 Gene

Gene Families for MESTIT1 Gene

HGNC:
  • LNCRNA :Long non-coding RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MESTIT1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MESTIT1 Gene

Function for MESTIT1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MESTIT1 Gene

Localization for MESTIT1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MESTIT1 Gene

Pathways for MESTIT1 Gene

SuperPathways for MESTIT1 Gene

No Data Available

Interacting Proteins for MESTIT1 Gene

Gene Ontology (GO) - Biological Process for MESTIT1 Gene

None

No data available for Pathways by source for MESTIT1 Gene

Transcripts for MESTIT1 Gene

mRNA/cDNA for MESTIT1 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MESTIT1 Gene

MEST intronic transcript 1, antisense RNA:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MESTIT1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MESTIT1 Gene

No ASD Table

Relevant External Links for MESTIT1 Gene

GeneLoc Exon Structure for
MESTIT1
ECgene alternative splicing isoforms for
MESTIT1

Expression for MESTIT1 Gene

SOURCE GeneReport for Unigene cluster for MESTIT1 Gene Hs.627349

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MESTIT1 Gene

Orthologs for MESTIT1 Gene

Evolution for MESTIT1 Gene

ENSEMBL:
Gene Tree for MESTIT1 (if available)
TreeFam:
Gene Tree for MESTIT1 (if available)

No data available for Orthologs for MESTIT1 Gene

Paralogs for MESTIT1 Gene

No data available for Paralogs for MESTIT1 Gene

Variants for MESTIT1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MESTIT1 Gene

Variant ID Type Subtype PubMed ID
nsv831130 CNV Loss 17160897
nsv831131 CNV Loss 17160897

Relevant External Links for MESTIT1 Gene

HapMap Linkage Disequilibrium report
MESTIT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MESTIT1 Gene

Disorders for MESTIT1 Gene

No disorders were found for MESTIT1 Gene.

No data available for UniProtKB/Swiss-Prot for MESTIT1 Gene

Publications for MESTIT1 Gene

  1. Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32. (PMID: 12095916) Nakabayashi K. … Scherer S.W. (Hum. Mol. Genet. 2002) 2 3
  2. Searching for genomic variants in the MESTIT1 transcript in Silver-Russell syndrome patients. (PMID: 12746419) Meyer E. … Eggermann T. (J. Med. Genet. 2003) 3
  3. Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST- flanking region at human chromosome 7q32. (PMID: 14962666) Yamada T. … Kishino T. (Genomics 2004) 3
  4. The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver- Russell syndrome. (PMID: 12676894) Bentley L. … Moore G.E. (J. Med. Genet. 2003) 23
  5. An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa. (PMID: 11821432) Li T. … Hoffman A.R. (J. Biol. Chem. 2002) 3

Products for MESTIT1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MESTIT1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MESTIT1
    • Block miRNA regulation of MESTIT1 using miScript Target Protectors

    Sources for MESTIT1 Gene

    Back to Top

    Content