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MEST intronic transcript 1, antisense RNA(Previous names: MEST intronic transcript 1, antisense RNA (non-protein...)
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Aliases
for MESTIT1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): non-coding RNA
Quality score for this RNA gene is 2
| Aliases |
|---|
| MEST Intronic Transcript 1, Antisense RNA1 2 | | MEST-IT2 | | MEST-AS11 2 | | MEST-IT12 | | NCRNA000401 2 | | PEG1-AS2 | | MEST Intronic Transcript 1, Antisense RNA (Non-Protein Coding)1 | | |
Export aliases for MESTIT1 gene to outside databasesPrevious GC identifers: GC07U900012 GC07M124489 |
Summaries
for MESTIT1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MESTIT1:
This gene encodes a non-protein coding antisense RNA that is imprinted, and preferentially expressed from the paternalallele. It is located in an intron of MEST gene in the opposite orientation, and shares the promoter region in commonwith one of the promoters (P2) of MEST gene. The antisense RNA is expressed predominantly in testis and mature motilespermatozoa, suggesting that it may be involved in the regulation of MEST expression during development.(provided byRefSeq, Oct 2010)
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Genomic Views
for MESTIT1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MESTIT1 gene promoter:
USF1 AML1a HTF XBP-1 LUN-1 LCR-F1 AREB6 USF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MESTIT1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MESTIT1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q32.2 HGNC cytogenetic band: 7q32.2MESTIT1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M130126: view genomic region
(about GC identifiers)
Start:
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130,126,898 bp from pter |
End:
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130,131,013 bp from pter |
Size:
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4,116 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 129,512,301-129,516,416 |
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Proteins
for MESTIT1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB: --
|
Protein
Domains /
Families
for MESTIT1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for MESTIT1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MESTIT1 |
|
Pathways & Interactions
for MESTIT1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MESTIT1
|
Drugs & Compounds
for MESTIT1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MESTIT1
Search CenterWatch for drugs/clinical trials and news about MESTIT1 
|
Transcripts
for MESTIT1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for MESTIT1: MEST intronic transcript 1, antisense RNA Hs.627349 [show with all ESTs]Unigene Representative Sequence: NR_004382
Additional cDNA sequence: NR_004382.1 1 DOTS entry: DT.95269672
GeneLoc Exon Structure
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Expression
for MESTIT1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for MESTIT1:none
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
SOURCE GeneReport for Unigene cluster: Hs.627349
SABiosciences Custom PCR Arrays for MESTIT1
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MESTIT1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MESTIT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MESTIT1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MESTIT1 |
Orthologs
for MESTIT1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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--
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Paralogs
for MESTIT1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MESTIT1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for MESTIT1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MESTIT1 for disorders About GeneDecksing
OMIM gene information: 607794
OMIM disorders: --
1  disease for MESTIT1: About MalaCardssilver-russell syndrome
Export disorders for MESTIT1 gene to outside databases
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Publications
for MESTIT1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MESTIT1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MESTIT1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32. (PubMed id 12095916)1, 3 Nakabayashi K....Scherer S.W. (2002)
- Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST- flanking region at human chromosome 7q32. (PubMed id 14962666)1 Yamada T.... Kishino T. (2004)
- Searching for genomic variants in the MESTIT1 transcript in Silver-Russell syndrome patients. (PubMed id 12746419)1 Meyer E....Eggermann T. (2003)
- An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa. (PubMed id 11821432)1 Li T....Hoffman A.R. (2002)
- The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver- Russell syndrome. (PubMed id 12676894)9 Bentley L.... Moore G.E. (2003)
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External Searches for MESTIT1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing MESTIT1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MESTIT1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MESTIT1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MESTIT1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for MESTIT1 gene:
Search GeneIP for patents involving MESTIT1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MESTIT1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MESTIT1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MESTIT1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MESTIT1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MESTIT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MESTIT1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MESTIT1 |
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| | | | Search Tocris compounds for MESTIT1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MESTIT1 |
|  |  |  | | | | Search ThermoFisher Antibodies for MESTIT1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MESTIT1 |
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