Aliases for MESDC2 Gene
External Ids for MESDC2 Gene
Previous GeneCards Identifiers for MESDC2 Gene
GeneCards Summary for MESDC2 Gene
MESDC2 (Mesoderm Development Candidate 2) is a Protein Coding gene. Diseases associated with MESDC2 include Albinism, Oculocutaneous, Type Ii. Among its related pathways are Non-Canonical Wnt Pathway and Wnt / Hedgehog / Notch. GO annotations related to this gene include low-density lipoprotein particle receptor binding.
UniProtKB/Swiss-Prot for MESDC2 Gene
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.