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MELK Gene

protein-coding GIFtS: 62

GC09P036562

maternal embryonic leucine zipper kinase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 2.7.11.1 ^³
HPK38 ^²
KIAA0175 ^¹, ², ³, ⁵
OTTHUMP00000046113 ^²
hMELK ^³
hPK38 ^³

Descriptions
Protein kinase PK38 ^³
maternal embryonic leucine zipper kinase ^²
pEg3 kinase ^²

External Ids
HGNC: 16870¹
Entrez Gene: 9833²
UniProtKB: Q14680³
Ensembl: ENSG00000165304⁷

Search outside databases for aliases for MELK gene

Previous GC identifers: GC09P036885 GC09P036742

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MELK_HUMAN, Q14680

Function: Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be

involved in the inhibition of spliceosome assembly during mitosis

Gene Wiki entry for MELK

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MELK gene

Entrez Gene cytogenetic band: 9p13.2 Ensembl cytogenetic band: 9p13.2 HGNC cytogenetic band: 9p13.1

MELK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09P036562: (about GC identifiers)

Start:	36,562,873 bp from pter
End:	36,667,679 bp from pter
Size:	104,807 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000009.10 NT_008413.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: MELK_HUMAN, Q14680 (See protein sequence)

Recommended Name: Maternal embryonic leucine zipper kinase

Size: 651 amino acids; 74642 Da

Subunit: Interacts with ZNF622 and PPP1R8

Subcellular location: Cytoplasm (Potential)

Secondary accessions: B1AMQ6 Q7L3C3

Post-translational modifications:

Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8

(Probable)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_055606.1

ENSEMBL proteins:

ENSP00000298048

Human Recombinant Proteins

	Invitrogen human recombinant proteins for MELK
	Millipore Purified and/or Recombinant MELK Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MELK)
	Human Recombinant Proteins from Abnova (MELK)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

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Antibodies for MELK:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of MELK
	Sigma-Aldrich Antibodies for MELK
	R&D Systems Antibodies for MELK
	Cell Signaling Technology (CST) Antibodies for MELK
	Antibodies from Abcam (MELK), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MELK)
	Novus Biologicals Antibodies for MELK

Assays for MELK:

	Invitrogen Assays for MELK
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q14680

ProtoNet protein and cluster: Q14680

1 Blocks protein family: IPB001772 Kinase-associated

UniProtKB/Swiss-Prot: MELK_HUMAN, Q14680

Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1

subfamily

Similarity: Contains 1 KA1 (kinase-associated) domain

Similarity: Contains 1 protein kinase domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MELK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MELK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014791

Applied Biosystems Silencer® siRNAs for MELK

Sigma-Aldrich siRNA and siRNA Panels for MELK

Sigma-Aldrich shRNA Panels and shRNA for MELK

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_014791
Myc/DDK tagged cDNA clone in CMV expression vector: NM_014791
untagged cDNA clones in CMV expression vector (see all 2): NM_014791

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_014791

UniProtKB/Swiss-Prot: MELK_HUMAN, Q14680

Function: Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be

involved in the inhibition of spliceosome assembly during mitosis

Catalytic activity: ATP + a protein = ADP + a phosphoprotein

Enzyme Number (IUBMB): EC 2.7.11.1

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0004674	protein serine/threonine kinase activity	IEA	--
GO:0005515	protein binding	IPI	17280616
GO:0005524	ATP binding	IEA	--
GO:0016740	transferase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for MELK

4 Interacting proteins for MELK (ENSP00000298048³ Q14680¹) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
BCL2L14	Q9BZR8¹	STRING (score=.845) EBI-1046702, EBI-1385773
ZNF622	ENSP00000310042³	STRING (score=.992)
MYBL2	ENSP00000217026³	STRING (score=.954)
PPP1R8	ENSP00000311677³	STRING (score=.819)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	protein amino acid phosphorylation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MELK
1 Novoseek chemical compound relationship for MELK gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
leucine	66.60	9	17280616 (2), 17722061 (2), 17960622 (2), 16216881 (1) (see all 6)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MELK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MELK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014791

Sigma-Aldrich siRNA and siRNA Panels for MELK

Sigma-Aldrich shRNA Panels and shRNA for MELK

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014791

REFSEQ mRNAs for MELK gene:

NM_014791.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014791

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014791
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_014791
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_014791

Additional cDNA sequence:

AB183427.1 AB183428.1 AB267395.1 AK222811.1 AK293284.1 AK293423.1 AK293447.1 AK296820.1

AK299164.1 AK300761.1 AK300821.1 AK301131.1 AK302374.1 AK309470.1 BC014039.2 CR605252.1

D79997.1

12 DOTS entries:

DT.212642 DT.121191407 DT.121191399 DT.121191419 DT.91711226 DT.100777414 DT.100777416 DT.102828545

DT.91742966 DT.97843505 DT.97843506 DT.100777415

24/99 AceView cDNA sequences (see all 99 ):

BM927868 BQ650221 BM851510 BU622206 BC014039 CR605252 NM_014791 AI637653

D79997 AA307070 CF141336 BQ071315 BQ064763 AI753377 AA835959 AL135150

BM823308 AU124892 AL554470 BM787111 BP383349 BM754132 AI870210 BQ221427

highest scoring ESTs for MELK:

D79997 AA460956 AA587220 AA664563 AA744782 AA744784 AA767453 AA768291 AA835959 AA903137

Unigene Cluster for MELK:

Maternal embryonic leucine zipper kinase

Hs.184339 [show with all ESTs]

Unigene Representative Sequence: NM_014791

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MELK (see all 6 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4	^	5	^	6a	·	6b	·	6c	·	6d	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20
SP1:									-		-										-		-
SP2:											-										-		-
SP3:											-				-						-		-
SP4:
SP5:											-

About this scheme

ECgene alternative splicing isoforms for MELK

1 Ensembl transcript including schematic representation:

ENST00000298048

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MELK expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MELK

¹ / ² / ³

3 probe-sets matching MELK gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
38847_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	D79997	1.00	1.00	1.00	1
204825_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_014791	0.60	1.00	0.82	1
204825_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGGTTTTGTA

SOURCE GeneReport for Unigene cluster: Hs.184339
Expression variation in blood from EXPOLDB for MELK
UniProtKB/Swiss-Prot: MELK_HUMAN, Q14680
Tissue specificity: Expressed in placenta, kidney, thymus, testis, ovary and intestine

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MELK gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MELK¹	--	maternal embryonic leucine zipper kinase	92.73(n) 91.71(a)	481608 XM_538730.2 XP_538730.2
chimpanzee (Pan troglodytes)	MELK¹	--	maternal embryonic leucine zipper kinase	99.44(n) 99.54(a)	465095 XM_001168960.1 XP_001168960.1
cow (Bos taurus)	MELK¹	--	maternal embryonic leucine zipper kinase	91.08(n) 89.69(a)	520088 XM_598320.3 XP_598320.2
rat (Rattus norvegicus)	Melk¹	--	maternal embryonic leucine zipper kinase	84.86(n) 84.6(a)	362510 XM_342828.3 XP_342829.1
mouse (Mus musculus)	Melk^{1, 5}	4 (26.70 cM)⁵	maternal embryonic leucine zipper kinase^{1, 5}	84.24(n)¹ 84.29(a)¹	17279¹ NM_010790.2¹ NP_034920.2¹ AI327312⁵ AK010498⁵ (see all 26)

About this table Species with no ortholog for MELK

ENSEMBL Gene Tree for MELK

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MELK gene

NUAK2² NUAK1² MGC42105²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/553 NCBI SNPs in MELK are shown (see all 553 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 117)

AB	SNP ID	Valid	Chr 9 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs12347708^1,2	C,F,H	36667608(+)	`TATGTG/AAATGT`	1	--	ut3¹		7	EU EA WA NA	562
	rs13440297^1,2	F,H	36573668(+)	`CTGGAG/TAGATG`	1	E/X	non¹		4	EU EA WA	406
	rs12685407^1,2	C,H	36667421(+)	`AAGTTC/AATTGG`	1	--	ut3¹ ese³		4	EU EA WA	418
	rs34655121^1,2	C,F	36641819(+)	`TTTAAG/AGCTTT`	1	K/R	mis¹		4	EU EA WA	420
	rs35142210^1,2	C,F	36597660(+)	`ATACAA/GGAAGA`	1	K/R	mis¹		4	EU EA WA	420
	rs35233455^1,2	C	36579555(+)	`CAAAAC/TGGAGA`	1	T/M	mis¹		4	EU EA WA	420
	rs2068826^1,2	H	36661008(-)	`CAATTC/ACACTG`	1	X/E	non¹ ese³		4	EU EA WA	420
	rs2274473^1,2	A,C,F,H,O	36664842(-)	`GTCACA/GTTATA`	1	N/N	syn¹		16	EU EA WA NA	1472
	rs1137377^1,2	H	36641829(+)	`TCTTCT/CTTCTC`	1	S/S	syn¹ ese³ trp³		4	EU EA WA	412
	rs2483640^1,2	A,C,F,H,O	36632191(+)	`ATAACG/AATCGT`	1	--	int¹		11	NA EU EA WA	922

About this table

HapMap Linkage Disequilibrium images for MELK (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 607025

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/21 PubMed articles for MELK gene (see all 21 ):

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)^{2, 3, 4} Nagase T....Nomura N. (1996)
Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1. (PubMed id 14699119)^{1, 3, 4} Vulsteke V.... Bollen M. (2004)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Phosphorylation of a novel zinc-finger-like protein, ZPR9, by murine protein serine/threonine kinase 38 (MPK38). (PubMed id 11802789)^{3, 4} Seong H.-A.... Ha H. (2002)
New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo. (PubMed id 9136115)^{2, 3} Heyer B.S....Ackerman S.L. (1997)
Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas. (PubMed id 17960622)^{1, 3} Marie S.K....Caballero O.L. (2008)
Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. (PubMed id 17722061)^{1, 3} Nakano I....Kornblum H.I. (2008)
Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family. (PubMed id 17280616)^{1, 3} Lin M.L....Katagiri T. (2007)
Human pEg3 kinase associates with and phosphorylates CDC25B phosphatase: a potential role for pEg3 in cell cycle regulation. (PubMed id 12400006)^{1, 3} Davezac N....Tassan J.P. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9833	HGNC: 16870	AceView: MELK	Ensembl:ENSG00000165304	euGenes: HUgn9833
ECgene: MELK	H-InvDB: MELK

(According to HUGE)
About This Section

HUGE: KIAA0175

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for MELK
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MELK:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MELK-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MELK		Antibodies for MELK
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MELK		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MELK)
	Antibodies (MELK)
	Chimera RNAi (MELK)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for MELK

	Recombinant Proteins (MELK)
	Antibodies (MELK)

Search OriGene for MELK

Search Tocris compounds for MELK

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for MELK

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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MELK Gene at Home site.
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MELK Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for MELK

Summaries
for MELK

Genomic Location
for MELK

Proteins
for MELK

Protein Domains/
Families
for MELK

Gene Function
for MELK

Pathways & Interactions
for MELK

Drugs & Compounds
for MELK

Transcripts
for MELK

Expression
for MELK

Orthologs
for MELK

Paralogs
for MELK

SNPs/Variants
for MELK

Disorders & Mutations
for MELK

Medical News
for MELK

Publications
for MELK

Search for MELK

Genome Databases showing MELK

Other Databases showing MELK

Specialized Databases showing MELK

Licensable Technologies
for MELK

Services
for MELK

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MELK Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor MELK

Summariesfor MELK

Genomic Locationfor MELK

Proteinsfor MELK

Protein Domains/Familiesfor MELK

Gene Functionfor MELK

Pathways & Interactionsfor MELK

Drugs & Compoundsfor MELK

Transcriptsfor MELK

Expression for MELK

Orthologsfor MELK

Paralogsfor MELK

SNPs/Variantsfor MELK

Disorders & Mutationsfor MELK

Medical Newsfor MELK

Publicationsfor MELK

Search for MELK

Genome Databases showing MELK

Other Databases showing MELK

Specialized Databases showing MELK

Licensable Technologiesfor MELK

Servicesfor MELK

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MELK

Summaries
for MELK

Genomic Location
for MELK

Proteins
for MELK

Protein Domains/
Families
for MELK

Gene Function
for MELK

Pathways & Interactions
for MELK

Drugs & Compounds
for MELK

Transcripts
for MELK

Expression
for MELK

Orthologs
for MELK

Paralogs
for MELK

SNPs/Variants
for MELK

Disorders & Mutations
for MELK

Medical News
for MELK

Publications
for MELK

Licensable Technologies
for MELK

Services
for MELK