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MEIS3 Gene

protein-coding   GIFtS: 43
GCID: GC19M047906

Meis Homeobox 3

(Previous names: Meis1, myeloid ecotropic viral integration site 1 homolog...)
Microbiology & Infectious Diseases Congress
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at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Meis Homeobox 31 2
Meis1-Related Protein 22 3
MRG22 3
Meis1, Myeloid Ecotropic Viral Integration Site 1 Homolog 3 (Mouse)1
Homeobox Protein Meis32
Meis1, Myeloid Ecotropic Viral Integration Site 1 Homolog 32

External Ids:    HGNC: 295371   Entrez Gene: 569172   Ensembl: ENSG000001054197   UniProtKB: Q996873   

Export aliases for MEIS3 gene to outside databases

Previous GC identifers: GC17P016056 GC17P016804 GC17P015633 GC19M052598


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MEIS3 Gene:
MEIS3 (Meis homeobox 3) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription. An important paralog of this gene is MEIS2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MEIS3 gene promoter:
         CREB   USF1   USF-1   NRSF form 1   CUTL1   E4BP4   NRSF form 2   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMEIS3 promoter sequence
   Search Chromatin IP Primers for MEIS3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MEIS3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.32   Ensembl cytogenetic band:  19q13.32   HGNC cytogenetic band: 19q13.32

MEIS3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MEIS3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M047906:  view genomic region     (about GC identifiers)

Start:
47,906,381 bp from pter      End:
47,922,785 bp from pter
Size:
16,405 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MEIS3_HUMAN, Q99687 (See protein sequence)
Recommended Name: Homeobox protein Meis3  
Size: 375 amino acids; 41115 Da
Secondary accessions: A8K1N5 Q6NT73 Q8TC66 Q9NPW2
Alternative splicing: 3 isoforms:  Q99687-1   Q99687-2   Q99687-3   

Explore the universe of human proteins at neXtProt for MEIS3: NX_Q99687

Explore proteomics data for MEIS3 at MOPED


See MEIS3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001009813.1  NP_064545.1  

ENSEMBL proteins: 
 ENSP00000388667   ENSP00000333552   ENSP00000453757   ENSP00000453934   ENSP00000453307  
 ENSP00000454073   ENSP00000452854   ENSP00000475941   ENSP00000453249   ENSP00000476248  

MEIS3 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for MEIS3

MEIS3 Antibody Products:

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LSBio Antibodies in human, mouse, rat for MEIS3

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Cloud-Clone Corp. CLIAs for MEIS3


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
TALE: Homeoboxes / TALE class

3 InterPro protein domains:
 IPR008422 Homeobox_KN_domain
 IPR001356 Homeobox_dom
 IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry Q99687

ProtoNet protein and cluster: Q99687

UniProtKB/Swiss-Prot: MEIS3_HUMAN, Q99687
Similarity: Belongs to the TALE/MEIS homeobox family
Similarity: Contains 1 homeobox DNA-binding domain


MEIS3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:
     Genatlas biochemistry entry for MEIS3:
homeo domain protein,murine Meis1 (myeloid ecotropic viral integration site 1) ortholog,PBX1 related,ubiquitously
expressed,binding DNA cooperatively with the heterodimer E2A/myogenic transcription factors

     Gene Ontology (GO): 5 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
GO:0003677DNA binding ----
GO:0003682chromatin binding IEA--
GO:0003700sequence-specific DNA binding transcription factor activity ----
GO:0043565sequence-specific DNA binding IDA17178831
     
MEIS3 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for MEIS3:
 Increased gamma-H2AX phosphory 

     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Meis3):
 no phenotypic analysis 

MEIS3 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MEIS3
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MEIS3

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MEIS3
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MEIS3

miRNA
Products:
    
miRTarBase miRNAs that target MEIS3:
hsa-mir-335-5p (MIRT016926), hsa-mir-130b-5p (MIRT038310)

Block miRNA regulation of human, mouse, rat MEIS3 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate MEIS3 (see all 11):
hsa-miR-98 hsa-let-7d hsa-let-7c hsa-let-7i hsa-miR-374a* hsa-let-7g hsa-let-7e hsa-miR-499-5p
SwitchGear 3'UTR luciferase reporter plasmidMEIS3 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for MEIS3
Predesigned siRNA for gene silencing in human, mouse, rat MEIS3

Gene Editing
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Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MEIS3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MEIS3

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEIS3


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
MEIS3_HUMAN, Q99687: Nucleus (Probable)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus4
cytosol2
extracellular1
peroxisome1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

MEIS3 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MEIS3
Interactions:

    Search GeneGlobe Interaction Network for MEIS3

STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

Selected Interacting proteins for MEIS3 (Q996873 ENSP000003335524) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
InteractantInteraction Details
GeneCardExternal ID(s)
JDP2Q8WYK23, ENSP000002675694I2D: score=1 STRING: ENSP00000267569
PBX4Q9BYU13, ENSP000002512034I2D: score=1 STRING: ENSP00000251203
HOXA13P312713, ENSP000002227534I2D: score=3 STRING: ENSP00000222753
HOXB7ENSP000002391654STRING: ENSP00000239165
MTX2ENSP000002494424STRING: ENSP00000249442
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006355regulation of transcription, DNA-templated ----
GO:0043066negative regulation of apoptotic process ----
GO:0051897positive regulation of protein kinase B signaling IEA--
GO:2001234negative regulation of apoptotic signaling pathway IEA--

MEIS3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MEIS3



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for MEIS3 gene (2 alternative transcripts): 
NM_001009813.2  NM_020160.2  

Unigene Cluster for MEIS3:

Meis homeobox 3
Hs.380923  [show with all ESTs]
Unigene Representative Sequence: NM_020160
14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000561204(uc002pgr.3) ENST00000441740 ENST00000331559(uc002pgs.3 uc002pgt.3 uc010eld.3)
ENST00000560245(uc002pgp.3) ENST00000561096(uc002pgq.3) ENST00000561293
ENST00000560253(uc002pgo.3) ENST00000558555 ENST00000559524 ENST00000607695
ENST00000559338 ENST00000557833 ENST00000607330 ENST00000561040(uc002pgw.3)

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat MEIS3 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate MEIS3 (see all 11):
hsa-miR-98 hsa-let-7d hsa-let-7c hsa-let-7i hsa-miR-374a* hsa-let-7g hsa-let-7e hsa-miR-499-5p
SwitchGear 3'UTR luciferase reporter plasmidMEIS3 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for MEIS3
Predesigned siRNA for gene silencing in human, mouse, rat MEIS3
Clone
Products:
     
OriGene clones in human, mouse for MEIS3 (see all 12)
OriGene ORF clones in mouse, rat for MEIS3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for MEIS3
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MEIS3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MEIS3
Primer
Products:
    
OriGene qPCR primer pairs and template standards for MEIS3
OriGene qSTAR qPCR primer pairs in human, mouse for MEIS3
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MEIS3
  QuantiTect SYBR Green Assays in human, mouse, rat MEIS3
  QuantiFast Probe-based Assays in human, mouse, rat MEIS3

Additional mRNA sequence: 

AB209455.1 AK098710.1 AK289950.1 AY091593.1 BC014430.1 BC025404.1 BC042183.1 BC045741.1 
BC069251.1 

19 DOTS entries:

DT.40215875  DT.95072774  DT.100757358  DT.121502990  DT.97847939  DT.91944163  DT.97847938  DT.101961250 
DT.101981371  DT.121502992  DT.100783117  DT.121503012  DT.91703329  DT.100702575  DT.95179990  DT.97793175 
DT.101960952  DT.91662826  DT.97856979 

Selected AceView cDNA sequences (see all 121):

BM783223 CK821639 BM783530 BM931531 BM783677 AK126593 BX394586 BM758664 
AK098710 CR613863 BM772967 BQ279147 BM783523 CR612502 CR605977 BQ003275 
CR613682 BQ225399 BC025404 BM783116 AA378474 BF726093 BM759933 CR596359 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for MEIS3    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13
SP1:                                                                                                
SP2:        -     -     -                                                                           
SP3:                                                                                                
SP4:                                                                                                
SP5:              -     -                                                                           


ECgene alternative splicing isoforms for MEIS3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MEIS3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGGGCCTGAG
MEIS3 Expression
About this image


MEIS3 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 2) fully expand
 
 Eye (Sensory Organs)
         Retina
 
 Stomach (Gastrointestinal Tract)
MEIS3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MEIS3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.380923
    Custom PCR Arrays for MEIS3
Primer
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OriGene qPCR primer pairs and template standards for MEIS3
OriGene qSTAR qPCR primer pairs in human, mouse for MEIS3
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QuantiFast Probe-based Assays in human, mouse, rat MEIS3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEIS3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for MEIS3 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Meis31 , 5 Meis homeobox 31, 5 86.76(n)1
90.13(a)1
  7 (8.76 cM)5
175371  NM_008627.31  NP_032653.21 
 161750905 
lizard
(Anolis carolinensis)
Reptilia --
--
73(a)
many ↔ many
GL344351.1(8818-12530)
African clawed frog
(Xenopus laevis)
Amphibia MGC525462 similar to myeloid ecotropic viral integration site-related more 76.26(n)    BC044024.1 
zebrafish
(Danio rerio)
Actinopterygii meis36
myeloid ecotropic viral integration site 3
59(a)
1 ↔ 1
15(6727919-6753991) ENSDARG00000002795
fruit fly
(Drosophila melanogaster)
Insecta hth6
homothorax
42(a)
1 → many
3R(6335569-6464386)


ENSEMBL Gene Tree for MEIS3 (if available)
TreeFam Gene Tree for MEIS3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for MEIS3 gene
MEIS22  TGIF2LY2  PKNOX12  TGIF22  PKNOX22  TGIF2LX2  MEIS12  TGIF12  
12 SIMAP similar genes for MEIS3 using alignment to 9 protein entries:     MEIS3_HUMAN (see all proteins):
HB103    MEIS3P2    MEIS3P1    MEIS1    MEIS2    TGIF2
meis1    TGIF2LY    TGIF1    PKNOX2    PKNOX1    WUGSC

MEIS3 for paralogs           About GeneDecksing


4 Pseudogenes.org Pseudogenes for MEIS3
PGOHUM00000237233 PGOHUM00000262123 PGOHUM00000237290 PGOHUM00000262124


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MEIS3 (see all 515)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1416408491,2
--47906132(+) CAGGCA/GTGCAC 2 -- ds50010--------
rs126108941,2
C,F,H--47906154(+) AGCAAT/CTCGTT 2 -- ds50015Minor allele frequency- C:0.13NA WA EA 364
rs1851554321,2
C--47906234(+) CCACTC/TGCCTT 2 -- ds50010--------
rs2006747721,2
--47906405(+) TCATT-/AAAAAA 2 -- ut310--------
rs18808531,2
C,F,A,H--47906491(+) ACCCTC/ACTTCC 2 -- ut31 ese3 trp37Minor allele frequency- A:0.07NS EA NA MN 604
rs115566371,2
C,F--47906518(+) CCCGTC/GCCTTC 2 -- ut31 ese3 trp32Minor allele frequency- G:0.25NA 4
rs1904064541,2
--47906535(+) CTGGCA/GGCGAG 2 -- ut310--------
rs1812688581,2
--47906586(+) CAGCTC/TGGGTC 2 -- ut310--------
rs126201,2
C,F--47906711(-) CTCAAC/TGCCTA 2 -- ut31 ese33Minor allele frequency- T:0.23MN NA 192
rs1131150681,2
C,F--47906982(+) GTGACG/AAGAAA 2 -- int12Minor allele frequency- A:0.04CSA WA 120

HapMap Linkage Disequilibrium report for MEIS3 (47906381 - 47922785 bp)

Structural Variations
     Database of Genomic Variants (DGV) 7 variations for MEIS3:    About this table    
Variant IDTypeSubtypePubMed ID
nsv517901CNV Loss19592680
esv2479786CNV Loss19546169
nsv912201CNV Loss21882294
nsv428366CNV Loss18775914
nsv9738CNV Gain18304495
nsv521341CNV Gain19592680
dgv1107e1CNV Complex17122850

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MEIS3
DNA2.0 Custom Variant and Variant Library Synthesis for MEIS3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for MEIS3 gene integrated from 10 sources:
(articles sorted by number of sources associating them with MEIS3)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. Identification of a conserved family of Meis1-related homeobox genes. (PubMed id 9049632)1, 2 Steelman S.... Buchberg A.M. (Genome Res. 1997)
  3. Identification of a new family of Pbx-related homeobox genes. (PubMed id 8950991)1, 3 Nakamura T....Copeland N.G. (Oncogene 1996)
  4. An autoinhibitory effect of the homothorax domain of Meis2. (PubMed id 20553494)1 Hyman-Walsh C.... Wotton D. (FEBS J. 2010)
  5. Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon. (PubMed id 17178831)1 Shim S....Park S. (Mol. Cell. Biol. 2007)
  6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
  7. Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction. (PubMed id 15617687)1 Williams T.M....Innis J.W. (Dev. Biol. 2005)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 56917 HGNC: 29537 AceView: MEIS3 Ensembl:ENSG00000105419 euGenes: HUgn56917
ECgene: MEIS3 H-InvDB: MEIS3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MEIS3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MEIS3 gene:
Search GeneIP for patents involving MEIS3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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