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Aliases for MEIOC Gene

Aliases for MEIOC Gene

  • Meiosis Specific With Coiled-Coil Domain 2 3 5
  • Meiosis-Specific With Coiled-Coil Domain Protein 3 4
  • C17orf104 3 4
  • Chromosome 17 Open Reading Frame 104 2
  • Uncharacterized Protein C17orf104 3

External Ids for MEIOC Gene

Previous HGNC Symbols for MEIOC Gene

  • C17orf104

Summaries for MEIOC Gene

GeneCards Summary for MEIOC Gene

MEIOC (Meiosis Specific With Coiled-Coil Domain) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEIOC Gene

Genomics for MEIOC Gene

Regulatory Elements for MEIOC Gene

Enhancers for MEIOC Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MEIOC on UCSC Golden Path with GeneCards custom track

Genomic Location for MEIOC Gene

Chromosome:
17
Start:
44,656,394 bp from pter
End:
44,690,308 bp from pter
Size:
33,915 bases
Orientation:
Plus strand

Genomic View for MEIOC Gene

Genes around MEIOC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MEIOC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MEIOC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MEIOC Gene

Proteins for MEIOC Gene

  • Protein details for MEIOC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUB1-MEIOC_HUMAN
    Recommended name:
    Meiosis-specific coiled-coil domain-containing protein MEIOC
    Protein Accession:
    A2RUB1
    Secondary Accessions:
    • B4DXJ2
    • B5MD93
    • B9EGQ6
    • C4AM97
    • Q4G0Y1
    • Q8IVZ7
    • Q8NA45

    Protein attributes for MEIOC Gene

    Size:
    952 amino acids
    Molecular mass:
    107559 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH35159.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI32823.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI36643.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for MEIOC Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MEIOC Gene

Proteomics data for MEIOC Gene at MOPED

Post-translational modifications for MEIOC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MEIOC Gene

No data available for DME Specific Peptides for MEIOC Gene

Domains & Families for MEIOC Gene

Protein Domains for MEIOC Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MEIOC: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MEIOC Gene

Function for MEIOC Gene

genes like me logo Genes that share phenotypes with MEIOC: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MEIOC Gene

Localization for MEIOC Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MEIOC Gene

Pathways & Interactions for MEIOC Gene

SuperPathways for MEIOC Gene

No Data Available

Interacting Proteins for MEIOC Gene

Gene Ontology (GO) - Biological Process for MEIOC Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MEIOC Gene

Drugs & Compounds for MEIOC Gene

No Compound Related Data Available

Transcripts for MEIOC Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MEIOC Gene

No ASD Table

Relevant External Links for MEIOC Gene

GeneLoc Exon Structure for
MEIOC
ECgene alternative splicing isoforms for
MEIOC

Expression for MEIOC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expression patterns with MEIOC: view

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MEIOC Gene

Orthologs for MEIOC Gene

This gene was present in the common ancestor of animals.

Orthologs for MEIOC Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C19H17orf104 35
  • 92.29 (n)
  • 90.85 (a)
C17orf104 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H17orf104 35
  • 92.69 (n)
  • 90.73 (a)
C17orf104 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm1564 35
  • 90.61 (n)
  • 88.64 (a)
Meioc 16
Gm1564 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf104 35
  • 99.54 (n)
  • 98.95 (a)
C17orf104 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563746 35
  • 90.71 (n)
  • 88.85 (a)
oppossum
(Monodelphis domestica)
Mammalia C17orf104 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C17orf104 36
  • 55 (a)
OneToOne
chicken
(Gallus gallus)
Aves C27H17ORF104 35
  • 67.91 (n)
  • 58.51 (a)
C17orf104 36
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf104 36
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496184 35
  • 56.51 (n)
  • 42.05 (a)
zebrafish
(Danio rerio)
Actinopterygii C17orf104 36
  • 29 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y39A1A.9 36
  • 26 (a)
OneToOne
Species with no ortholog for MEIOC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MEIOC Gene

ENSEMBL:
Gene Tree for MEIOC (if available)
TreeFam:
Gene Tree for MEIOC (if available)

Paralogs for MEIOC Gene

No data available for Paralogs for MEIOC Gene

Variants for MEIOC Gene

Sequence variations from dbSNP and Humsavar for MEIOC Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs8073475 - 44,666,842(+) CAGAG(A/T)TGTTT reference, missense
rs9907151 - 44,666,870(+) ATACA(A/C/G)TGAAA reference, missense
rs3897489 -- 44,676,505(-) TTCTA(C/T)GGTAA intron-variant
rs3897490 -- 44,676,022(-) TTACA(C/T)GGATT intron-variant, downstream-variant-500B
rs6416902 -- 44,674,239(+) ATATA(C/T)CAAGA intron-variant, utr-variant-3-prime

Variation tolerance for MEIOC Gene

Residual Variation Intolerance Score: 63.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.51; 77.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MEIOC Gene

HapMap Linkage Disequilibrium report
MEIOC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MEIOC Gene

Disorders for MEIOC Gene

Relevant External Links for MEIOC

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MEIOC
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MEIOC

No disorders were found for MEIOC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MEIOC Gene

Publications for MEIOC Gene

  1. Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. (PMID: 26742488) Abby E. … Livera G. (Nat Commun 2016) 2 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier L.D. … Marra M. (Genome Res. 1996) 3

Products for MEIOC Gene

Sources for MEIOC Gene

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