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MEIOB Gene

protein-coding   GIFtS: 34
GCID: GC16M001886

Meiosis Specific With OB Domains

(Previous name: chromosome 16 open reading frame 73)
(Previous symbol: C16orf73)
  Search for MEIOB
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Meiosis Specific With OB Domains1 2
C16orf731 2 3
Chromosome 16 Open Reading Frame 731
gs1292
Meiosis-Specific With OB Domain-Containing Protein2
EC 3.1.-.-3

External Ids:    HGNC: 285691   Entrez Gene: 2545282   Ensembl: ENSG000001620397   UniProtKB: Q8N6353   

Export aliases for MEIOB gene to outside databases

Previous GC identifer: GC16M001884


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MEIOB Gene:
MEIOB (meiosis specific with OB domains) is a protein-coding gene.

UniProtKB/Swiss-Prot: MEIOB_HUMAN, Q8N635
Function: Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for
double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not
required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci
after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful
homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for MEIOB
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MEIOB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MEIOB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

MEIOB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MEIOB gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M001886:  view genomic region     (about GC identifiers)

Start:
1,883,984 bp from pter      End:
1,934,295 bp from pter
Size:
50,312 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MEIOB_HUMAN, Q8N635 (See protein sequence)
Recommended Name: Meiosis-specific with OB domain-containing protein  
Size: 442 amino acids; 49313 Da
Subunit: Component of a multiprotein complex with RPA2 and SPATA22 (By similarity)
Sequence caution: Sequence=AAH29829.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAK61296.1; Type=Erroneous gene model prediction;
Secondary accessions: B1AK39 C9J0S1 Q96RY0
Alternative splicing: 2 isoforms:  Q8N635-1   Q8N635-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MEIOB: NX_Q8N635

Explore proteomics data for MEIOB at MOPED


See MEIOB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001157032.1  NP_689977.2  

ENSEMBL proteins: 
 ENSP00000457416   ENSP00000314484   ENSP00000380504   ENSP00000456880   ENSP00000457427  
 ENSP00000390778   ENSP00000391033  

MEIOB Human Recombinant Protein Products:

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Search eBioscience for ELISAs for MEIOB 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR012340 NA-bd_OB-fold

Graphical View of Domain Structure for InterPro Entry Q8N635

ProtoNet protein and cluster: Q8N635

UniProtKB/Swiss-Prot: MEIOB_HUMAN, Q8N635
Similarity: Belongs to the MEIOB family
Similarity: Contains 1 OB DNA-binding domain


Find genes that share domains with MEIOB           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: MEIOB_HUMAN, Q8N635
Function: Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for
double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not
required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci
after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful
homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By
similarity)

     Enzyme Number (IUBMB): EC 3.1.-.-1

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003682chromatin binding ISS--
GO:0003697single-stranded DNA binding ISS--
GO:0008310single-stranded DNA 3'-5' exodeoxyribonuclease activity ISS--
     
Find genes that share ontologies with MEIOB           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MEIOB
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miRNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
MEIOB_HUMAN, Q8N635: Cytoplasm (By similarity). Nucleus (By similarity). Chromosome (By similarity).
Note=Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is
dependent on SPATA22 (By similarity)

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--
GO:0005694chromosome IEA--
GO:0005737cytoplasm ISS--

Find genes that share ontologies with MEIOB           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MEIOB
Interactions:

    Search GeneGlobe Interaction Network for MEIOB

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for MEIOB (ENSP000003805044) via UniProtKB, MINT, STRING, and/or I2D (see all 75)
InteractantInteraction Details
GeneCardExternal ID(s)
DNA2ENSP000003821334STRING: ENSP00000382133
MSH2ENSP000002331464STRING: ENSP00000233146
POLR1AENSP000002638574STRING: ENSP00000263857
MRE11AENSP000003258634STRING: ENSP00000325863
MSH6ENSP000002344204STRING: ENSP00000234420
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Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000712resolution of meiotic recombination intermediates ISS--
GO:0000724double-strand break repair via homologous recombination ISS--
GO:0000738DNA catabolic process, exonucleolytic ISS--
GO:0007129synapsis ISS--
GO:0007140male meiosis ISS--

Find genes that share ontologies with MEIOB           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MEIOB



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for MEIOB gene (2 alternative transcripts): 
NM_001163560.2  NM_152764.2  

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000470044(uc010uvr.2) ENST00000325962 ENST00000397344 ENST00000490154
ENST00000496541 ENST00000460494 ENST00000563416(uc021tal.1) ENST00000412554(uc010uvq.1 uc002cne.2)
ENST00000452149
miRNA
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Primer
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  QuantiFast Probe-based Assays in human, mouse, rat MEIOB

4 AceView cDNA sequences:

NM_152764 BC029829 BG193877 BG187699 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for MEIOB    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
SP1:                                                                                -         
SP2:                                                                                          
SP3:                                                                                          
SP4:        -     -                                                                           
SP5:                                                                                          


ECgene alternative splicing isoforms for MEIOB

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --


MEIOB expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Ovary (Reproductive System)    fully expand to see all 2 entries
         XX Germ Cells Ovigerous Cord
         Ovigerous Cord
 
 Gonad
         XX Germ Cells Ovigerous Cord
 
 Testis (Reproductive System)
MEIOB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MEIOB Protein Expression

UniProtKB/Swiss-Prot: MEIOB_HUMAN, Q8N635
Tissue specificity: In fetal gonads, specifically expressed in the ovary starting at the 14th weeks post
fertilization

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEIOB

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for MEIOB gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Meiob1 , 5 RIKEN cDNA 4930528F23 gene5
meiosis specific with OB domains1
86.78(n)1
84.86(a)1
  17 (12.53 cM)5
751781  NM_029197.11  NP_083473.11 
 248043825 
chicken
(Gallus gallus)
Aves C14H16ORF731 chromosome 14 open reading frame, human C16orf73 73.06(n)
69.72(a)
  416539  XM_414840.4  XP_414840.4 
lizard
(Anolis carolinensis)
Reptilia MEIOB6
meiosis specific with OB domains
68(a)
1 ↔ 1
GL343263.1(1368304-1379303)
tropical clawed frog
(Xenopus tropicalis)
Amphibia meiob1 meiosis specific with OB domains 68.16(n)
65.02(a)
  100489575  XM_002935865.2  XP_002935911.2 
zebrafish
(Danio rerio)
Actinopterygii meiob1 meiosis specific with OB domains 58.91(n)
51.66(a)
  101882335  XM_005156169.1  XP_005156226.1 
fruit fly
(Drosophila melanogaster)
Insecta hdm1 hold'em 40.3(n)
29.21(a)
  31705  NM_132194.1  NP_572422.1 


ENSEMBL Gene Tree for MEIOB (if available)
TreeFam Gene Tree for MEIOB (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for MEIOB gene
1 SIMAP similar gene for MEIOB using alignment to 4 protein entries:     MEIOB_HUMAN (see all proteins):
C16orf73

Find genes that share paralogs with MEIOB           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MEIOB (see all 937)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs25753551,2
C--1849068(+) caaagT/Gttgca 1 -- us2k17Minor allele frequency- G:0.07NA WA 14
rs118639401,2
C,F,H--1890793(+) tgatcT/Cacctg 2 -- int11Minor allele frequency- C:0.00NA 2
rs620384251,2
C,F--1890841(+) CCACCG/ACGCCC 2 -- int12Minor allele frequency- A:0.50NA WA 4
rs1874940531,2
--1890843(+) ACCACA/GCCCAG 2 -- int10--------
rs1390145851,2
--1890997(+) GGAGT-/TTAC  
        
TTTCT
2 -- int10--------
rs615053581,2
F--1891019(+) TTTTTC/TTTTTT 2 -- int11Minor allele frequency- T:0.50NA 4
rs1929608871,2
--1891049(+) TTTCAC/TTCTTC 2 -- int10--------
rs1499234661,2
C--1891096(+) CACCGC/TGACCT 2 -- int10--------
rs116428941,2
H--1891162(+) acaggG/Tgcccg 2 -- int10--------
rs558298671,2
C--1891166(+) GTGCCC/TGCCAC 2 -- int11Minor allele frequency- T:0.50WA 2

HapMap Linkage Disequilibrium report for MEIOB (1883984 - 1934295 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for MEIOB: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MEIOB
DNA2.0 Custom Variant and Variant Library Synthesis for MEIOB

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for MEIOB gene integrated from 10 sources:
(articles sorted by number of sources associating them with MEIOB)
    Utopia: connect your pdf to the dynamic
world of online information

  1. MEIOB targets single-strand DNA and is necessary for meiotic recombination. (PubMed id 24068956)1, 2 Souquet B.... Livera G. (PLoS Genet. 2013)
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  3. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (Hum. Mol. Genet. 2001)
  4. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  6. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 254528 HGNC: 28569 AceView: MGC35212 Ensembl:ENSG00000162039 euGenes: HUgn254528
ECgene: MEIOB H-InvDB: MEIOB

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MEIOB Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MEIOB gene:
Search GeneIP for patents involving MEIOB

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MEIOB  
 OriGene qPCR primer pairs and template standards for MEIOB   OriGene Protein Over-expression Lysate for MEIOB  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for MEIOB  
 OriGene qSTAR qPCR primer pairs in human, mouse for MEIOB   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for MEIOB   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for MEIOB   OriGene Custom Protein Services for MEIOB  

 
 
 Block miRNA regulation of human, mouse, rat MEIOB using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MEIOB
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MEIOB Predesigned siRNA for gene silencing in human, mouse, rat MEIOB
 QuantiFast Probe-based Assays in human, mouse, rat MEIOB QuantiTect SYBR Green Assays in human, mouse, rat MEIOB
 Custom PCR Arrays for MEIOB Search Chromatin IP Primers for MEIOB
 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MEIOB Search GeneGlobe Interaction Network for MEIOB
 Search Regulatory tfbs for MEIOB
 GenScript Custom Purified and Recombinant Proteins Services for MEIOB GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for MEIOB
 GenScript Custom Assay Services for MEIOB GenScript Custom overexpressing Cell Line Services for MEIOB
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for MEIOB
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 MEIOB antibodies
 Antibodies for MEIOB
 See all of Abcam's Antibodies, Kits and Proteins for MEIOB
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for MEIOB
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEIOB
 SwitchGear 3'UTR luciferase reporter plasmids for MEIOB
 Browse SwitchGear Promoter luciferase reporter plasmids for MEIOB
 Search ThermoFisher Antibodies for MEIOB
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MEIOB
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MEIOB
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MEIOB
 LSBio Antibodies in human, mouse, rat for MEIOB
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for MEIOB
  Search eBioscience for proteins for MEIOB
  Search eBioscience for elisas for MEIOB
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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