Aliases for MEGF11 Gene
Aliases for MEGF11 Gene
External Ids for MEGF11 Gene
- HGNC: 29635
- Entrez Gene: 84465
- Ensembl: ENSG00000157890
- OMIM: 612454
- UniProtKB: A6BM72
Previous GeneCards Identifiers for MEGF11 Gene
- GC15M061979
- GC15M059286
- GC15M063766
- GC15M063903
- GC15M063974
- GC15M066187
- GC15M043012
Summaries for MEGF11 Gene
GeneCards Summary for MEGF11 Gene
MEGF11 (Multiple EGF Like Domains 11) is a Protein Coding gene. An important paralog of this gene is MEGF10.
UniProtKB/Swiss-Prot for MEGF11 Gene
-
May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).
Additional gene information for MEGF11 Gene
- Monarch Initiative
- Search for MEGF11 at DataMed
- Search for MEGF11 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEGF11 Gene
Genomics for MEGF11 Gene
GeneHancer (GH) Regulatory Elements for MEGF11 Gene
Promoters and enhancers for MEGF11 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH15I066253 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE | 550.8 | +0.0 | 46 | 0.6 | ZNF76 SIN3A ZNF2 ZEB1 ZNF335 GLIS2 ZNF366 ZNF143 EGR2 SP3 | MEGF11 TIPIN LOC105370868 GC15P068669 | |
| GH15I066154 | Promoter/Enhancer | 1.1 | EPDnew dbSUPER | 561.1 | +99.9 | 99889 | 0.1 | SMARCA5 GLIS2 ZFP3 NBN PRDM10 MLLT1 DPF2 BCLAF1 | MEGF11 DIS3L GC15P068669 | |
| GH15I066153 | Enhancer | 1.3 | FANTOM5 ENCODE dbSUPER | 11.1 | +99.6 | 99611 | 0.4 | PKNOX1 ARNT KLF17 BMI1 FEZF1 BATF GLIS2 SCRT2 ATF7 KLF7 | DIS3L MEGF11 GC15P068669 | |
| GH15I066137 | Enhancer | 0.6 | dbSUPER | 20.9 | +114.7 | 114714 | 2.5 | STAT1 ZNF189 FEZF1 OSR2 PRDM6 POLR2A SCRT2 ZNF341 BCL6B | MEGF11 GC15P068669 GC15M066111 | |
| GH15I065954 | Enhancer | 0.9 | ENCODE dbSUPER | 10.4 | +299.2 | 299154 | 1.1 | ZIC2 ETS1 ZFHX2 POLR2A ZNF600 FOS ZBTB20 EGR2 YY2 REST | MEGF11 GC15P069445 LOC105370867 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MEGF11 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MEGF11 Gene
Genomic Locations for MEGF11 Gene
- chr15:65,895,079-66,253,747
- (GRCh38/hg38)
- Size:
- 358,669 bases
- Orientation:
- Minus strand
- chr15:66,187,417-66,546,085
- (GRCh37/hg19)
Genomic View for MEGF11 Gene
Genes around MEGF11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q22.31 by Ensembl
- 15q22.31 by Entrez Gene
- 15q22.31 by HGNC
MEGF11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MEGF11 Gene
Proteins for MEGF11 Gene
-
Protein details for MEGF11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6BM72-MEG11_HUMAN
- Recommended name:
- Multiple epidermal growth factor-like domains protein 11
- Protein Accession:
- A6BM72
- Q17R86
- Q6UXS5
- Q8ND91
- Q96KG6
Protein attributes for MEGF11 Gene
- Size:
- 1044 amino acids
- Molecular mass:
- 110844 Da
- Quaternary structure:
-
- Homopolymer (Probable). Does not interact with MEGF10.
- SequenceCaution:
-
- Sequence=BAB47410.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD38994.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for MEGF11 Gene
Post-translational modifications for MEGF11 Gene
- Glycosylation at posLast=270270 and isoforms=2, 3531
Other Protein References for MEGF11 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for MEGF11
- Novus Biologicals Antibodies for MEGF11
- Invitrogen Antibodies for MEGF11
- GeneTex MEGF11 antibody for MEGF11
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MEGF11
- Origene Custom Protein Services for MEGF11
- Novus Biologicals proteins for MEGF11
- antibodies-online: Search results for 6 available MEGF11 Proteins ranked by validation data
- Compare Top MEGF11 Proteins
-
Quality Products:
- Search GeneTex for Proteins for MEGF11
Assay Products
No data available for DME Specific Peptides for MEGF11 Gene
Domains & Families for MEGF11 Gene
Gene Families for MEGF11 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for MEGF11 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MEGF11 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
A6BM72- Family:
-
- Belongs to the MEGF family.
Function for MEGF11 Gene
Molecular function for MEGF11 Gene
- UniProtKB/Swiss-Prot Function:
- May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).
Phenotypes From GWAS Catalog for MEGF11 Gene
Phenotypes for MEGF11 Gene
- MGI mutant phenotypes for MEGF11:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MEGF11:
Animal Models for MEGF11 Gene
- MGI Knock Outs for MEGF11:
-
- Megf11 tm1a(EUCOMM)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for MEGF11 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MEGF11 gene
- Search ViGene Biosciences for MEGF11
CRISPR Products
-
OriGene CRISPR knockouts for MEGF11
- genomics-online: gRNA clones - Search results for 70 available MEGF11 gene related products
- Overview of 70 available MEGF11 gene related products
- Applied Biological Materials CRISPR for MEGF11
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MEGF11
- GenScript: Design CRISPR guide RNA sequences for MEGF11
miRNA for MEGF11 Gene
- miRTarBase miRNAs that target MEGF11
miRNA Products
- Search ViGene Biosciences for MEGF11
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for MEGF11
- Browse OriGene Inhibitory RNA Products For MEGF11
- genomics-online: shRNA clones - Search results for 70 available MEGF11 gene related products
- Overview of 70 available MEGF11 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MEGF11 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Applied Biological Materials Clones for MEGF11
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MEGF11
-
ViGene Biosciences adenoviral particle packaged cDNA for MEGF11 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MEGF11 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MEGF11 gene
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MEGF11 Gene
Localization for MEGF11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MEGF11 Gene
- Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 3 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0016323 | basolateral plasma membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MEGF11 Gene
Pathways & Interactions for MEGF11 Gene
No Data Available
Interacting Proteins for MEGF11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010842 | retina layer formation | ISS | -- |
| GO:0034109 | homotypic cell-cell adhesion | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for MEGF11 Gene
Transcripts for MEGF11 Gene
mRNA/cDNA for MEGF11 Gene
- (7) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (38) Selected AceView cDNA sequences:
- (15) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MEGF11 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MEGF11
- genomics-online: gRNA clones - Search results for 70 available MEGF11 gene related products
- Overview of 70 available MEGF11 gene related products
- Applied Biological Materials CRISPR for MEGF11
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MEGF11
- GenScript: Design CRISPR guide RNA sequences for MEGF11
miRNA Products
- Search ViGene Biosciences for MEGF11
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for MEGF11
- Browse OriGene Inhibitory RNA Products For MEGF11
- genomics-online: shRNA clones - Search results for 70 available MEGF11 gene related products
- Overview of 70 available MEGF11 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MEGF11 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Applied Biological Materials Clones for MEGF11
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
| ExUns: | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29a | · | 29b | · | 29c | ^ | 30 | ^ | 31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | |||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||
| SP4: | - | ||||||||||||||||||||
| SP5: | |||||||||||||||||||||
| SP6: | |||||||||||||||||||||
| SP7: | |||||||||||||||||||||
| SP8: |
Expression for MEGF11 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Mature Horizontal Cells Inner Nuclear Layer
- Cholinergic Amacrine Cells Inner Nuclear Layer
- Cholinergic Amacrine Cells Ganglion Cell Layer
-
Neurons
- Mature Horizontal Cells Inner Nuclear Layer
- Cholinergic Amacrine Cells Inner Nuclear Layer
- Cholinergic Amacrine Cells Ganglion Cell Layer
-
Heart (Cardiovascular System)
- Atrioventricular Node Cells Atrioventricular Node
- Brain (Nervous System)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for MEGF11 Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x11.9) and Brain - Cerebellum (x11.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MEGF11 Gene
NURSA nuclear receptor signaling pathways regulating expression of MEGF11 Gene:
MEGF11SOURCE GeneReport for Unigene cluster for MEGF11 Gene:
Hs.712886Evidence on tissue expression from TISSUES for MEGF11 Gene
- Nervous system(4.3)
Primer Products
-
OriGene qPCR primer pairs for MEGF11
- genomics-online: primer clones - Search results for 70 available MEGF11 gene related products
- Overview of 70 available MEGF11 gene related products
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MEGF11 Gene
Orthologs for MEGF11 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MEGF11 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | MEGF11 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | MEGF11 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Megf11 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Megf11 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MEGF11 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MEGF11 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MEGF11 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | megf11 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | megf11 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007256 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | drpr 35 33 34 |
|
||
| CG18172 35 |
|
|
|||
| BG:DS00180.14 35 |
|
|
|||
| worm (Caenorhabditis elegans) |
Secernentea | ced-1 33 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for MEGF11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for MEGF11 Gene
(4) SIMAP similar genes for MEGF11 Gene using alignment to 3 proteins:
Pseudogenes.org Pseudogenes for MEGF11 Gene
Variants for MEGF11 Gene
| SNP ID | Clin | Chr 15 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000006473 | -- | 65,985,287(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000009234 | -- | 66,236,284(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000013188 | -- | 66,122,802(-) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000020435 | -- | 65,899,017(-) | A/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000026551 | -- | 66,026,001(-) | C/T | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1228n106 | CNV | deletion | 24896259 |
| esv1121128 | CNV | insertion | 17803354 |
| esv1421197 | CNV | insertion | 17803354 |
| esv2749788 | CNV | deletion | 23290073 |
| esv2749789 | CNV | deletion | 23290073 |
| esv2760035 | CNV | loss | 17122850 |
| esv2761875 | CNV | gain | 21179565 |
| esv3306749 | CNV | mobile element insertion | 20981092 |
| esv3309331 | CNV | mobile element insertion | 20981092 |
| esv3361194 | CNV | insertion | 20981092 |
| esv3405191 | CNV | duplication | 20981092 |
| esv3429747 | CNV | insertion | 20981092 |
| esv3552585 | CNV | deletion | 23714750 |
| esv3581747 | CNV | loss | 25503493 |
| esv3636762 | CNV | loss | 21293372 |
| esv3636765 | CNV | gain | 21293372 |
| esv3636767 | CNV | loss | 21293372 |
| esv5067 | CNV | loss | 18987735 |
| esv987792 | CNV | deletion | 20482838 |
| esv994579 | CNV | insertion | 20482838 |
| nsv1047176 | CNV | gain | 25217958 |
| nsv1047588 | CNV | loss | 25217958 |
| nsv1055090 | CNV | gain | 25217958 |
| nsv1070704 | CNV | deletion | 25765185 |
| nsv1122977 | CNV | deletion | 24896259 |
| nsv114 | CNV | insertion | 15895083 |
| nsv1152514 | CNV | deletion | 26484159 |
| nsv1571 | CNV | insertion | 18451855 |
| nsv1572 | CNV | deletion | 18451855 |
| nsv1573 | CNV | insertion | 18451855 |
| nsv1574 | CNV | insertion | 18451855 |
| nsv471684 | CNV | gain | 15918152 |
| nsv472137 | CNV | novel sequence insertion | 20440878 |
| nsv472331 | CNV | novel sequence insertion | 20440878 |
| nsv472945 | CNV | novel sequence insertion | 20440878 |
| nsv472962 | CNV | novel sequence insertion | 20440878 |
| nsv472973 | CNV | novel sequence insertion | 20440878 |
| nsv473041 | CNV | novel sequence insertion | 20440878 |
| nsv473945 | CNV | novel sequence insertion | 20440878 |
| nsv474014 | CNV | novel sequence insertion | 20440878 |
| nsv474229 | CNV | novel sequence insertion | 20440878 |
| nsv474598 | CNV | novel sequence insertion | 20440878 |
| nsv474666 | CNV | novel sequence insertion | 20440878 |
| nsv474732 | CNV | novel sequence insertion | 20440878 |
| nsv474744 | CNV | novel sequence insertion | 20440878 |
| nsv475266 | CNV | novel sequence insertion | 20440878 |
| nsv475280 | CNV | novel sequence insertion | 20440878 |
| nsv475304 | CNV | novel sequence insertion | 20440878 |
| nsv475465 | CNV | novel sequence insertion | 20440878 |
| nsv475611 | CNV | novel sequence insertion | 20440878 |
| nsv475839 | CNV | novel sequence insertion | 20440878 |
| nsv476899 | CNV | novel sequence insertion | 20440878 |
| nsv476959 | CNV | novel sequence insertion | 20440878 |
| nsv476984 | CNV | novel sequence insertion | 20440878 |
| nsv478528 | CNV | novel sequence insertion | 20440878 |
| nsv478701 | CNV | novel sequence insertion | 20440878 |
| nsv478881 | CNV | novel sequence insertion | 20440878 |
| nsv478949 | CNV | novel sequence insertion | 20440878 |
| nsv478995 | CNV | novel sequence insertion | 20440878 |
| nsv479083 | CNV | novel sequence insertion | 20440878 |
| nsv479116 | CNV | novel sequence insertion | 20440878 |
| nsv479138 | CNV | novel sequence insertion | 20440878 |
| nsv479150 | CNV | novel sequence insertion | 20440878 |
| nsv479270 | CNV | novel sequence insertion | 20440878 |
| nsv479473 | CNV | novel sequence insertion | 20440878 |
| nsv479495 | CNV | novel sequence insertion | 20440878 |
| nsv480211 | CNV | novel sequence insertion | 20440878 |
| nsv480318 | CNV | novel sequence insertion | 20440878 |
| nsv480420 | CNV | novel sequence insertion | 20440878 |
| nsv480483 | CNV | novel sequence insertion | 20440878 |
| nsv480647 | CNV | novel sequence insertion | 20440878 |
| nsv480927 | CNV | novel sequence insertion | 20440878 |
| nsv480928 | CNV | novel sequence insertion | 20440878 |
| nsv481129 | CNV | novel sequence insertion | 20440878 |
| nsv481168 | CNV | novel sequence insertion | 20440878 |
| nsv481173 | CNV | novel sequence insertion | 20440878 |
| nsv481299 | CNV | novel sequence insertion | 20440878 |
| nsv481347 | CNV | novel sequence insertion | 20440878 |
| nsv509572 | CNV | insertion | 20534489 |
| nsv516488 | CNV | gain+loss | 19592680 |
| nsv569793 | CNV | gain | 21841781 |
| nsv833044 | CNV | loss | 17160897 |
| nsv957990 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
86.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
12.64;
94.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MEGF11 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MEGF11 Gene
Disorders for MEGF11 Gene
Additional Disease Information for MEGF11
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for MEGF11 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MEGF11 Gene
Publications for MEGF11 Gene
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2001) 2 3 4 58
- Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M … Yamada Y (American journal of hypertension 2010) 3 44 58
- Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T … Yamada Y (International journal of molecular medicine 2010) 3 44 58
- The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern. (PMID: 17498693) Suzuki E … Nakayama M (Experimental cell research 2007) 3 4 58
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4 58
Products for MEGF11 Gene
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for MEGF11
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MEGF11
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- Browse Antibodies at Cloud-Clone Corp.
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- Invitrogen Antibodies for MEGF11
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online: Search results for 14 available MEGF11 Antibodies ranked by validation data
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- antibodies-online: Search results for available MEGF11 related products ranked by validation data
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- Quality Products:
- GeneTex MEGF11 antibody for MEGF11
- Search GeneTex for Proteins for MEGF11
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- genomics-online: cdna clones - Search results for 70 available MEGF11 gene related products
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Sources for MEGF11 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew