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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MEGF11 Gene

protein-coding   GIFtS: 51
GCID: GC15M066187

Multiple EGF-Like-Domains 11

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Multiple EGF-Like-Domains 111 2
Multiple EGF-Like Domains Protein 112 3
KIAA17813 5
Multiple Epidermal Growth Factor-Like Domains Protein 112

External Ids:    HGNC: 296351   Entrez Gene: 844652   Ensembl: ENSG000001578907   OMIM: 6124545   UniProtKB: A6BM723   

Export aliases for MEGF11 gene to outside databases

Previous GC identifers: GC15M061979 GC15M059286 GC15M063766 GC15M063903 GC15M063974 GC15M043012


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MEGF11 Gene: 
MEGF11 (multiple EGF-like-domains 11) is a protein-coding gene. Diseases associated with MEGF11 include retinitis, and neuronitis. An important paralog of this gene is SCARF1.

UniProtKB/Swiss-Prot: MEG11_HUMAN, A6BM72
Function: May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal
neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring
that all parts of the visual field have access to a full set of processing elements (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MEGF11 gene promoter:
         GR   FAC1   POU2F1   Pax-5   POU2F1a   GR-alpha   POU6F1 (c2)   CUTL1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMEGF11 promoter sequence
   Search SABiosciences Chromatin IP Primers for MEGF11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MEGF11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.31   Ensembl cytogenetic band:  15q22.31   HGNC cytogenetic band: 15q22.31

MEGF11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MEGF11 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M066187:  view genomic region     (about GC identifiers)

Start:
66,187,417 bp from pter      End:
66,546,085 bp from pter
Size:
358,669 bases      Orientation:
minus strand

1 alternative location:
Chr15-,NW_003315944 5,553-357,692     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MEG11_HUMAN, A6BM72 (See protein sequence)
Recommended Name: Multiple epidermal growth factor-like domains protein 11 precursor  
Size: 1044 amino acids; 110844 Da
Subunit: Homopolymer (Probable). Does not interact with MEGF10
Subcellular location: Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass
type I membrane protein. Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes
firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10
Sequence caution: Sequence=BAB47410.2; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAD38994.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q17R86 Q6UXS5 Q8ND91 Q96KG6
Alternative splicing: 4 isoforms:  A6BM72-1   A6BM72-2   A6BM72-3   A6BM72-4   

Explore the universe of human proteins at neXtProt for MEGF11: NX_A6BM72

Explore proteomics data for MEGF11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A6BM72

  • MEGF11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MEGF11 Protein Expression
    REFSEQ proteins: NP_115821.2  
    ENSEMBL proteins: 
     ENSP00000386908   ENSP00000288745   ENSP00000456118   ENSP00000401400   ENSP00000414475  
     ENSP00000378987   ENSP00000378976   ENSP00000353919  

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    Cloud-Clone Corp. Proteins for MEGF11 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--
    GO:0016323basolateral plasma membrane IEA--

    MEGF11 for ontologies           About GeneDecksing



    MEGF11 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for MEGF11


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR011489 EMI_domain
     IPR002049 EGF_laminin
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry A6BM72

    ProtoNet protein and cluster: A6BM72

    UniProtKB/Swiss-Prot: MEG11_HUMAN, A6BM72
    Similarity: Belongs to the MEGF family
    Similarity: Contains 14 EGF-like domains
    Similarity: Contains 1 EMI domain


    MEGF11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MEG11_HUMAN, A6BM72
    Function: May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal
    neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring
    that all parts of the visual field have access to a full set of processing elements (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    MEGF11 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Megf11):
     nervous system  vision/eye 

    MEGF11 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MEGF11 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MEGF11 
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    SwitchGear 3'UTR luciferase reporter plasmidMEGF11 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MEGF11

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for MEGF11 (A6BM722, 3 ENSP000003869084) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATN1P542592, 3, ENSP000003490764MINT-2877232 MINT-2877251 I2D: score=3 STRING: ENSP00000349076
    GULP1Q9UBP93I2D: score=1 
    SNX2O607493I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010842retina layer formation ISS--
    GO:0034109homotypic cell-cell adhesion ISS--

    MEGF11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MEGF11 (MEG11)

    Search CenterWatch for drugs/clinical trials and news about MEGF11 / MEG11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MEGF11 gene: 
    NM_032445.2  

    Unigene Cluster for MEGF11:

    Multiple EGF-like-domains 11
    Hs.712886  [show with all ESTs]
    Unigene Representative Sequence: NM_032445
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409699(uc002apn.1) ENST00000288745(uc002apl.2) ENST00000478721
    ENST00000490495 ENST00000489275 ENST00000562154 ENST00000493192 ENST00000478590
    ENST00000564573 ENST00000455812 ENST00000484618 ENST00000474398 ENST00000469917
    ENST00000422354(uc002apm.2) ENST00000395625 ENST00000395614 ENST00000360698

    miRNA
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    8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate MEGF11 (see all 53):
    hsa-miR-376b hsa-let-7d hsa-miR-188-5p hsa-miR-128 hsa-let-7a-2* hsa-miR-624 hsa-miR-578 hsa-miR-488
    SwitchGear 3'UTR luciferase reporter plasmidMEGF11 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MEGF11
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MEGF11

    Additional mRNA sequence: 

    AB058677.1 AB300051.1 AK090663.1 BC029999.1 BC117419.1 BC126313.1 

    9 DOTS entries:

    DT.75193995  DT.121080094  DT.91944360  DT.40129195  DT.101978329  DT.403184  DT.406166  DT.91717542 
    DT.121080092 

    24/38 AceView cDNA sequences (see all 38):

    BM723031 BM677486 BC029999 AY358226 AB058677 AW131768 NM_032445 AA496110 
    AK090663 AL834326 AA293781 AA861104 AI027310 BM563529 BF529240 AA398355 
    AA496109 AW293834 AW103176 BX090443 AL044960 AI919451 BF529771 AI936445 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for MEGF11 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21a · 21b · 21c ^ 22 ^ 23 ^
    SP1:                    -     -                 -                                                                 -                 -           -     -     -   
    SP2:                                                                                                                                -           -     -     -   
    SP3:                                                                                                                                            -     -     -   
    SP4:                                                                                                                                                        -   
    SP5:                                                                                                                                                            

    ExUns: 24 ^ 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29a · 29b · 29c ^ 30 ^ 31
    SP1:  -     -     -     -     -           -     -     -               
    SP2:  -                                                               
    SP3:              -           -                 -     -               
    SP4:  -                                                               
    SP5:                                                                  


    ECgene alternative splicing isoforms for MEGF11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MEGF11 expression in normal human tissues (normalized intensities)      MEGF11 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MEGF11 Expression
    About this image


    MEGF11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Eye (Sensory Organs)    fully expand to see all 3 entries
             Mature Horizontal Cells Inner Nuclear Layer
     
     Brain (Nervous System)    fully expand to see all 2 entries
             cerebellum   
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
     
     Testis (Reproductive System)

    See MEGF11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MEGF11

    SOURCE GeneReport for Unigene cluster: Hs.712886
        SABiosciences Custom PCR Arrays for MEGF11
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MEGF11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MEGF11 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Megf111 , 5 multiple EGF-like-domains 111, 5 87.12(n)1
    90.59(a)1
      9 (34.67 cM)5
    2140581  NM_001134399.11  NP_001127871.11 
     643856265 
    chicken
    (Gallus gallus)
    Aves MEGF111 multiple EGF-like-domains 11 75.3(n)
    77.96(a)
      415545  XM_413915.3  XP_413915.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    84(a)
    72(a)
    (see all 3)
    possible ortholog
    1 ↔ many
    (see all 3)
    GL343921.1(27207-93585)
    GL343930.1(34104-87478)
    zebrafish
    (Danio rerio)
    Actinopterygii megf111 multiple EGF-like-domains 11 70.44(n)
    69.24(a)
      563468  XM_001921905.3  XP_001921940.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG181723
    drpr1
    draper1 44(a)
    (best of 3)3
    51.97(n)1
    41.18(a)1
      382181  NM_167911.21  NP_728660.21 
    worm
    (Caenorhabditis elegans)
    Secernentea ced-11 Protein CED-1 47.7(n)
    40.74(a)
      173064  NM_001026601.2  NP_001021772.1 


    ENSEMBL Gene Tree for MEGF11 (if available)
    TreeFam Gene Tree for MEGF11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MEGF11 gene
    SCARF12  PEAR12  MEGF102  SCARF22  
    4 SIMAP similar genes for MEGF11 using alignment to 3 protein entries:     MEG11_HUMAN (see all proteins):
    MEGF10    PEAR1    MEGF6    EGFEM1P

    MEGF11 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MEGF11
    PGOHUM00000246825


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/7750 SNPs in MEGF11 are shown (see all 7750)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs577899291,2
    C--43321544(+) AAAAT-/AAAATAAAATAAAAT/AAA
    ATAAAATAAAATAAAATAAAAT
    CATCA
    2 -- int1 cds11NA 2
    rs350246921,2
    C,F--43349296(+) TTGGGT/ATTTTT 1 -- int12Minor allele frequency- A:0.50NA 4
    rs714478891,2
    C--43349296(+) TTGGG-/TT/TTT
            
    TTTTT
    1 -- int11NA 2
    rs718601531,2
    C--46332468(+) TACCCCT/-CTCTT 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs783923621,2
    C--46383312(+) TTTTG-/GATTT 
            
    ATTTA
    1 -- int10--------
    rs1929009001,2
    --66187140(+) TGGTGC/TGATCT 1 -- ds50010--------
    rs1488173321,2
    C--66187234(+) CACCAC/GGCCCG 1 -- ds50010--------
    rs1434635491,2
    C--66187238(+) AGGCCC/TGGCTA 1 -- ds50010--------
    rs1850545661,2
    --66187245(+) GCTAAG/TTTTTT 1 -- ds50010--------
    rs169490831,2
    C,F,H--66188031(+) CTCCTC/GTGTAT 1 -- ut31 ese3 trp38Minor allele frequency- G:0.03NA NS EA WA 678

    HapMap Linkage Disequilibrium report for MEGF11 (66187417 - 66437417 bp, first 250kb of MEGF11)

    Structural Variations
         Database of Genomic Variants (DGV) 10/21 variations for MEGF11 (see all 21):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv5067CNV Deletion18987735
    esv987792CNV Deletion20482838
    esv2749789CNV Deletion23290073
    esv2749788CNV Deletion23290073
    nsv1574CNV Insertion18451855
    esv273604CNV Insertion20981092
    esv1121128CNV Insertion17803354
    esv994579CNV Insertion20482838
    esv1421197CNV Insertion17803354
    nsv509572CNV Insertion20534489


    Human Gene Mutation Database (HGMD): MEGF11
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MEGF11
    DNA2.0 Custom Variant and Variant Library Synthesis for MEGF11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612454    OMIM disorders: --

    2 diseases for MEGF11:    About MalaCards
    retinitis    neuronitis


    MEGF11 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MEGF11
    Human Genome Epidemiology (HuGE) Navigator: MEGF11 (2 documents)

    Export disorders for MEGF11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MEGF11 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with MEGF11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (2001)
    2. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    3. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    4. The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern. (PubMed id 17498693)1, 2 Suzuki E. and Nakayama M. (2007)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    6. A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study. (PubMed id 17903305)4 Murabito J.M....Hwang S.J. (2007)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    9. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84465 HGNC: 29635 AceView: MEGF11 Ensembl:ENSG00000157890 euGenes: HUgn84465
    ECgene: MEGF11 H-InvDB: MEGF11

    (According to HUGE)
    About This Section
    HUGE: KIAA1781

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MEGF11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MEGF11 gene:
    Search GeneIP for patents involving MEGF11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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