Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MEG8 Gene

Subcategory (RNA class) for MEG8 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for MEG8 Gene

  • Maternally Expressed 8 (Non-Protein Coding) 2 3 5
  • Long Intergenic Non-Protein Coding RNA 24 2 3
  • RNA Imprinted And Accumulated In Nucleus 2 3
  • Maternally Expressed (In Callipyge) 8 2 3
  • Imprinted RNA Near Meg3/Gtl2 2 3
  • Non-Protein Coding RNA 24 2
  • NCRNA00024 3
  • LINC00024 3
  • Rian 3
  • Bsr 3
  • Irm 3

External Ids for MEG8 Gene

Previous GeneCards Identifiers for MEG8 Gene

  • GC00U990903
  • GC14U900551
  • GC14P101361
  • GC14P081542
  • GC14P101227
  • GC14P101799

Summaries for MEG8 Gene

Entrez Gene Summary for MEG8 Gene

  • This gene is located in a cluster of imprinted genes on chromosome 14q32.3. It encodes a a non-protein coding transcript that is preferentially expressed from the maternal allele in skeletal muscle, and appears to be coordinately regulated with other imprinted genes in this region. [provided by RefSeq, Oct 2010]

GeneCards Summary for MEG8 Gene

MEG8 (Maternally Expressed 8 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEG8 Gene

Genomics for MEG8 Gene

Regulatory Elements for MEG8 Gene

Enhancers for MEG8 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MEG8 on UCSC Golden Path with GeneCards custom track

Genomic Location for MEG8 Gene

100,894,770 bp from pter
100,935,999 bp from pter
41,230 bases
Plus strand

Genomic View for MEG8 Gene

Genes around MEG8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MEG8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MEG8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MEG8 Gene

Proteins for MEG8 Gene

Post-translational modifications for MEG8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MEG8 Gene

Domains & Families for MEG8 Gene

Gene Families for MEG8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MEG8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MEG8 Gene

Function for MEG8 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MEG8 Gene

Localization for MEG8 Gene

Subcellular locations from

Jensen Localization Image for MEG8 Gene COMPARTMENTS Subcellular localization image for MEG8 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MEG8 Gene

Pathways & Interactions for MEG8 Gene

SuperPathways for MEG8 Gene

No Data Available

Interacting Proteins for MEG8 Gene

Gene Ontology (GO) - Biological Process for MEG8 Gene


No data available for Pathways by source and SIGNOR curated interactions for MEG8 Gene

Drugs & Compounds for MEG8 Gene

No Compound Related Data Available

Transcripts for MEG8 Gene

mRNA/cDNA for MEG8 Gene

(1) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MEG8 Gene

Maternally expressed 8 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MEG8 Gene

No ASD Table

Relevant External Links for MEG8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MEG8 Gene

mRNA expression in normal human tissues for MEG8 Gene

mRNA differential expression in normal tissues according to GTEx for MEG8 Gene

This gene is overexpressed in Pituitary (x12.1) and Adrenal Gland (x4.0).

SOURCE GeneReport for Unigene cluster for MEG8 Gene Hs.655789

genes like me logo Genes that share expression patterns with MEG8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MEG8 Gene

Orthologs for MEG8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MEG8 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SNORD112 36
  • 86 (a)
SNORD112 36
  • 75 (a)
(Canis familiaris)
Mammalia SNORD112 36
  • 91 (a)
(Pan troglodytes)
Mammalia SNORD112 36
  • 100 (a)
Species with no ortholog for MEG8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MEG8 Gene

Gene Tree for MEG8 (if available)
Gene Tree for MEG8 (if available)

Paralogs for MEG8 Gene

No data available for Paralogs for MEG8 Gene

Variants for MEG8 Gene

Sequence variations from dbSNP and Humsavar for MEG8 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs7140293 -- 100,893,817(+) AGGCC(C/T)TGGGA upstream-variant-2KB
rs752041 -- 100,900,995(-) CGGCC(C/T)TGGCA intron-variant
rs755488 -- 100,892,840(-) ATCAC(A/G)CCTGA upstream-variant-2KB
rs755830 -- 100,903,313(-) CTCAC(G/T)CTTGG intron-variant
rs7146460 -- 100,895,541(+) AAGCT(C/T)TTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MEG8 Gene

Variant ID Type Subtype PubMed ID
nsv902241 CNV Loss 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MEG8 Gene

Disorders for MEG8 Gene

Relevant External Links for MEG8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MEG8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MEG8 Gene

Publications for MEG8 Gene

  1. Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region. (PMID: 12045206) CavaillAc J. … Bachellerie J.P. (Hum. Mol. Genet. 2002) 2 3 67
  2. Human-ovine comparative sequencing of a 250-kb imprinted domain encompassing the callipyge (clpg) locus and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8. (PMID: 11337479) Charlier C. … Georges M. (Genome Res. 2001) 2 3
  3. Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening. (PMID: 11481034) Hatada I. … Kono T. (J. Biochem. 2001) 2 3
  4. Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants. (PMID: 12107410) Wistow G. … Peterson K. (Mol. Vis. 2002) 3

Products for MEG8 Gene

Sources for MEG8 Gene